Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns.The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

    Guyton & Hall's Textbook of Medical Physiology covers all of the major systems in the human body, while emphasizing system interaction, homeostasis, and pathophysiology. This very readable, easy-to-follow, and thoroughly updated, 11th Edition features a new full-color layout, short chapters, clinical vignettes, and shaded summary tables that allow for easy comprehension of the material.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Presents short, easy-to-read chapters in keeping with the Guyton and Hall tradition.Provides shaded summary tables for easy reference.Includes clinical vignettes, which allow readers to see core concepts applied to real-life situations.Offers specific discussions of pathophysiology in most clinical areas of medicine.Ensures a strong grasp of physiology concepts through well-illustrated discussions of the most essential principles.Now in full color! Offers access to the full text and other valuable features online via the STUDENT CONSULT website.Uses full-color illustrations throughout, including 486 figures, 277 charts and graphs, 100 brand-new line drawings, and 36 ECGs.Features a new full-color design that makes information more engaging and even easier to read.Updated throughout to reflect the latest knowledge in the field.

    In an overcrowded, underfunded medical system, she explores how more of us can be healthier, and how listening carefully to a patient’s experience can be as important as prescribing a pill. These dazzling essays show Hitchcock to be one of the most fearless and illuminating medical thinkers of our time – reasonable, insightful and deeply humane.

    From Mary Lamb, sister of Charles, who in the throes of a nervous breakdown turned on her mother with a kitchen knife, to Freud, Jung, and Lacan, who developed the new women-centered therapies, Lisa Appignanesi’s research traces how more and more of the inner lives and emotions of women have become a matter for medics and therapists. Here too is the story of how over the years symptoms and diagnoses have developed together to create fashions in illness and how treatments have succeeded or sometimes failed. Mad, Bad, and Sad takes us on a fascinating journey through the fragile, extraordinary human mind.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    Now in The Undiscovered Mind he focuses on the single most important scientific enterprise of all -- the effort to understand the human mind. Horgan takes us inside laboratories, hospitals, and universities to meet neuro-scientists, Freudian analysts, electroshock therapists, behavioral geneticists, evolutionary psychologists, artificial intelligence engineers, and philosophers of consciousness. He looks into the persistent explanatory gap between mind and body that Socrates pondered and shows that it has not been bridged. He investigates what he calls the "Humpty Dumpty dilemma," the fact that neuroscientists can break the brain and mind into pieces but cannot put the pieces back together again. He presents evidence that the placebo effect is the primary ingredient of psychotherapy, Prozac, and other treatments for mental disorders. As Horgan shows, the mystery of human consciousness, of why and how we think, remains so impregnable that to expect the attempts of scientific method and technology to penetrate it anytime soon is absurd.

    Daniel Mierlak, a psychiatrist for twenty-five years, on a journey to the stranger corners of human experience. Here you’ll meet: Tony, chauffeur to the fabulously rich, who overcomes crippling anxiety only to find himself descend into a homicidal rage following a botched cosmetic procedure. Amanda, hospitalized for mania, who sees a change to her medicine as an assassination attempt, and then stalks her doctor for a year after discharge. James, a schizophrenic hearing voices telling him to kill himself, whose piano playing leads to a shocking secret about his past. Psychiatric treatment is normally a private encounter and often misunderstood. In describing twelve of his most challenging cases, Dr. Mierlak brings you into his sessions, into his patients’ lives, and into the world of psychiatry. Get ready for some surprises.

    Our intimate connection with the world, skin protects us while advertising our health, our identity, and our individuality. This dazzling synthetic overview, written with a poetic touch and taking many intriguing side excursions, is a complete guidebook to the pliable covering that makes us who we are. Skin: A Natural History celebrates the evolution of three unique attributes of human skin: its naked sweatiness, its distinctive sepia rainbow of colors, and its remarkable range of decorations. Jablonski begins with a look at skin's structure and functions and then tours its three-hundred-million-year evolution, delving into such topics as the importance of touch and how the skin reflects and affects emotions. She examines the modern human obsession with age-related changes in skin, especially wrinkles. She then turns to skin as a canvas for self-expression, exploring our use of cosmetics, body paint, tattooing, and scarification. Skin: A Natural History places the rich cultural canvas of skin within its broader biological context for the first time, and the result is a tremendously engaging look at ourselves.

    The new edition from Chopra includes many topics encompassing the theory of structural dynamics and the application of this theory regarding earthquake analysis, response, and design of structures. No prior knowledge of structural dynamics is assumed and the manner of presentation is sufficiently detailed and integrated, to make the book suitable for self-study by students and professional engineers.

    In The Anatomy of Violence, Raine dissects the criminal mind with a fascinating, readable, and far-reaching scientific journey into the body of evidence that reveals the brain to be a key culprit in crime causation.  Raine documents from genetic research that the seeds of sin are sown early in life, giving rise to abnormal physiological functioning that cultivates crime. Drawing on classical case studies of well-known killers in history—including Richard Speck, Ted Kaczynski, and Henry Lee Lucas—Raine illustrates how impairments to brain areas controlling our ability to experience fear, make good decisions, and feel guilt predispose us to violence. He contends that killers can actually be coldhearted: something as simple as a low resting heart rate can give rise to violence. But arguing that biology is not destiny, he also sketches out provocative new biosocial treatment approaches that can change the brain and prevent violence.  Finally, Raine tackles the thorny legal and ethical dilemmas posed by his research, visualizing a futuristic brave new world where our increasing ability to identify violent offenders early in life might shape crime-prevention policies, for good and bad. Will we sacrifice our notions of privacy and civil rights to identify children as potential killers in the hopes of helping both offenders and victims? How should we punish individuals with little to no control over their violent behavior? And should parenting require a license? The Anatomy of Violence offers a revolutionary appraisal of our understanding of criminal offending, while also raising provocative questions that challenge our core human values of free will, responsibility, and punishment.From the Hardcover edition.

    Full of advice on how surgeons should use their heads as well as their hands - how to think, plan, and improvise - when, for example, operating on a massively bleeding trauma patient. Starts with general principles, continues with specific injuries to abdomen, chest, neck, and peripheral vessels. Generously illustrated throughout, with drawings produced specifically for this book. For residents, general surgeons with an interest in trauma, and for surgeons operating on badly wounded patients in isolated military, rural, or humanitarian settings. Asher Hirshberg and Kenneth L Mattox are trauma surgeons at the Ben Taub General Hospital, Houston, and professors at the Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA. Kenneth L Maddox is famous as the lead editor of McGraw Hill's classic text, Trauma, now in its fifth edition. This is going to be a GREAT book!

    Significantly revised and updated content throughout this edition brings you the latest information on the etiology, clinical features, histopathology, treatment, and prognosis of each disease entity, as well as cutting-edge topics such as bisphosphonate osteonecrosis, the oral complications associated with methamphetamine abuse, solitary fibrous tumors, gene mutation, and plasminogen deficiency.Over 1,300 clinical photos and radiographs, most in full color, facilitate identification and classification of lesions.Current concepts of pathogenesis and disease management help you understand the diseases that affect the oral and maxillofacial structures, formulate an accurate diagnosis, and institute proper treatment.Each chapter is logically organized by body system or disease group, enabling you to easily identify a specific condition.A comprehensive appendix of differential diagnosis among oral and maxillofacial disease processes helps you rule out invalid diagnoses.The bibliography divided by topic presented at the end of each chapter enables you to pursue supplemental literature.Highly accomplished authors and contributors with a broad range of clinical and classroom teaching experience provide well-balanced coverage of the entire subject.Chapter outlines at the beginning of each chapter allow immediate access to specific topics.Over 200 new illustrations have been added to this popular, visual reference.A new section on bisphosphonate-associated osteonecrosis thoroughly explores and illustrates this recently identified complication resulting from medications used to prevent bone loss in patients with multiple myeloma, metastatic tumors, and osteoporosis.A new section about the oral complications of methamphetamine abuse details characteristic oral manifestations such as meth mouth caries" and factitial injuries.Expanded coverage of oral piercings, intraoral tattoos, and other body modifications includes unusual entities such as tongue splitting and charm needles.A new section on transient lingual papillitis sheds light on this common cause of transitory tongue irritation.A new section on solitary fibrous tumors familiarizes you with this popular designation for certain benign fibrous neoplasms.A new section on hypoplasminogenemia (ligneous conjunctivitis), or plasminogen deficiency, includes images from a patient case that illustrate the characteristic gingival lesions associated with this rare but fascinating systemic condition.A new section on hereditary mucoepithelial dysplasia describes the characteristic oral manifestations that can lead you to accurately diagnose this condition, potentially preventing a woman with this disorder from having cytologically unusual cells misdiagnosed as carcinoma on her cervical PAP smears.A new section discusses the clinical and microscopic features of chronic ulcerative stomatitis, an immune-mediated condition of the oral mucosa that presents with erosive lesions and is often mistaken for lichen planus.The chapter on Forensic Dentistry has been thoroughly revised and updated by leading forensic odontology author, Dr. Edward Herschaft, to include the latest information on this fascinating topic.Several chapters have been updated to include the most current knowledge of specific gene mutations associated with hereditary oral disorders.

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?

    Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.

    Dr. William Owens explains, in clear language, the basics of respiratory failure and mechanical ventilation. This is a guide to keep in your jacket pocket, call room, or in the ICU. The second edition includes new chapters on capnography and acid-base problem solving, ventilator weaning protocols, and is updated to reflect current medical evidence. Conventional and unconventional modes of ventilation are examined and explained. PEEP, flow, ventilator liberation, and the care of the patient with prolonged respiratory failure are also covered. The goal of "The Ventilator Book" is to make difficult concepts easy to understand. Conventional medical textbooks are great references, but they are heavy and can't be easily carried around by clinicians who are busy taking care of patients. They also are written to be an exhaustive, authoritative reference, which means that they often contain far more information than what you need at the bedside to help with a difficult case. "The Ventilator Book" has enough information to teach anyone about mechanical ventilation, but not so much that reading it becomes intimidating.