For more than twenty years, Kitty Dukakis battled severe depression with every medication and treatment available. But it wasn't until she tried electroconvulsive therapy- ECT-that she began getting her life back for good. Written with award-winning medical reporter Larry Tye, "Shock" is both the personal story of how ECT dramatically changed Kitty Dukakis's life as well as a captivating look at the science behind ECT, the controversy surrounding it, and the history of its intriguing rebirth in this country. "Shock" explores the stigma afflicting ECT-still a treatment that many hospitals do not administer-and debunks long-held misconceptions about how it is performed. Though some continue to view ECT as a dangerous, even barbaric, procedure, as this book explains there is no scientific evidence to suggest that ECT damages the brain. It can cause side effects like memory loss, but they generally are not far-reaching or long-lasting, especially when newer, lower-impact techniques are employed. In fact, the U.S. surgeon general and the National Institutes of Health agree that for severe depression ECT is safe, and often more effective than antidepressants or psychotherapy. An eye-opening and powerful book about one of the most contentious medical treatments in history, Shock demystifies ECT and brings to life-through Kitty Dukakis's moving account -its impressive capacity to heal. For the millions who suffer from depression, bipolar disorder, and other mental illnesses, it offers real information, practical guidance, and hope.

    The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Renowned writer Meghan O’Rourke delivers a revelatory investigation into this elusive category of “invisible” illness that encompasses autoimmune diseases, post-treatment Lyme disease syndrome, and now long COVID, synthesizing the personal and the universal to help all of us through this new frontier. Drawing on her own medical experiences as well as a decade of interviews with doctors, patients, researchers, and public health experts, O’Rourke traces the history of Western definitions of illness, and reveals how inherited ideas of cause, diagnosis, and treatment have led us to ignore a host of hard-to-understand medical conditions, ones that resist easy description or simple cures. And as America faces this health crisis of extraordinary proportions, the populations most likely to be neglected by our institutions include women, the working class, and people of color. Blending lyricism and erudition, candor and empathy, O’Rourke brings together her deep and disparate talents and roles as critic, journalist, poet, teacher, and patient, synthesizing the personal and universal into one monumental project arguing for a seismic shift in our approach to disease. The Invisible Kingdom offers hope for the sick, solace and insight for their loved ones, and a radical new understanding of our bodies and our health.

    Wade identified abortion as a constitutional right over 40 years ago, it bears stigma--a proverbial scarlet A--in the United States. Millions participate in or benefit from an abortion, but few want to reveal that they have done so. Approximately one in five pregnancies in the US ends in abortion. Why is something so common, which has been legal so long, still a source of shame and secrecy? Why is it so regularly debated by politicians, and so seldom divulged from friend to friend, or loved one to loved one? This book explores the personal stigma that prevents many from sharing their abortion experiences with friends and family in private conversation, and the structural stigma that keeps it that way. It argues persuasively that America would benefit from working to reverse such stigma, providing readers with tools that may help them model ways of doing so.Our silence around private experience with abortion has distorted our public discourse. Both proponents and opponents of abortion's legality tend to focus on the extraordinary cases. This tendency keeps the public discourse polarized and contentious, and keeps the focus on the cases that occur the least. Katie Watson focuses instead on the remaining 95% of abortion cases. The book gives the reflective reader a more accurate impression of what the majority of American abortion practice really looks like. It explains why this public/private disjuncture exists, what it costs us, and what can be gained by including ordinary abortion in public debate.As Scarlet A explains, abortion has been a constitutional right for nearly 45 years, and it should remain one. What we need now are productive conversations about abortion ethics: how could or should people decide whether to exercise this right? Watson paints a rich, rarely seen picture of how patients and doctors currently think and act, and ultimately invites readers to draw their own conclusions.

    These three Great Untruths are part of a larger philosophy that sees young people as fragile creatures who must be protected and supervised by adults. But despite the good intentions of the adults who impart them, the Great Untruths are harming kids by teaching them the opposite of ancient wisdom and the opposite of modern psychological findings on grit, growth, and antifragility. The result is rising rates of depression and anxiety, along with endless stories of college campuses torn apart by moralistic divisions and mutual recriminations. This is a book about how we got here. First Amendment expert Greg Lukianoff and social psychologist Jonathan Haidt take us on a tour of the social trends stretching back to the 1980s that have produced the confusion and conflict on campus today, including the loss of unsupervised play time and the birth of social media, all during a time of rising political polarization. This is a book about how to fix the mess. The culture of “safety” and its intolerance of opposing viewpoints has left many young people anxious and unprepared for adult life, with devastating consequences for them, for their parents, for the companies that will soon hire them, and for a democracy that is already pushed to the brink of violence over its growing political divisions. Lukianoff and Haidt offer a comprehensive set of reforms that will strengthen young people and institutions, allowing us all to reap the benefits of diversity, including viewpoint diversity. This is a book for anyone who is confused by what’s happening on college campuses today, or has children, or is concerned about the growing inability of Americans to live and work and cooperate across party lines.

    As he walks with us through dark territories, he points out the significant and reflects on its meaning.”—Mary Pipher, Ph.D., author of Reviving OpheliaThe passage from adolescence to adulthood was once clear. Today, growing up has become more complex and confusing, as young men drift casually through college and beyond—hanging out, partying, playing with tech toys, watching sports. But beneath the appearance of a simple extended boyhood, a more dangerous social world has developed, far away from the traditional signposts and cultural signals that once helped boys navigate their way to manhood—a territory Michael Kimmel has identified as "Guyland."In mapping the troubling social world where men are now made, Kimmel offers a view into the minds and times of America's sons, brothers, and boyfriends, and he works toward redefining what it means to be a man today—and tomorrow. Only by understanding this world and this life stage can we enable young men to chart their own paths, stay true to themselves, and emerge safely from Guyland as responsible and fully formed male adults.

    Although it is usually seen as an unqualified success, the Battle for Normandy was actually a much more closely fought affair. In The D-Day Deception the author and journalist Alex Gerlis explores whether it would have been won at all without the Allied deception operation. It was not until the 1970s that details began to emerge the Allies’ top secret and audacious deception plan. Operation Fortitude succeeded in confusing the Germans about where the Allies were going to land: would it be Normandy, or the Pas de Calais? The D-Day Deception looks at the part the deception played in the eventual Allied victory and asks to what extent it may have been helped by those in the German High Command and intelligence organizations who by 1944 wanted to see a swift end to the war. Alex Gerlis was born in Grimsby, Lincolnshire and now lives with his family in West London. He was a BBC journalist for over 25 years, leaving in 2011 to concentrate on his writing. He is the author of The Best of Our Spies, a highly acclaimed espionage thriller based on D-Day and especially the deception operation that played a big part in its success. The Best of Our Spies was published in December 2012, since when it has featured prominently in the Amazon Kindle Spy best-selling lists and has over 180 Amazon reviews.

    Nashef tells heart-stopping stories of transplants, bypasses, coronary artery repair, and cardiac arrest. He also delivers humane advice about medical realities rarely observed: the futility of obsessing over diet, the necessity of calculating risks, the role of decision making, the resilience of doctor and patient alike, and the threadbare brilliance of the NHS.Nashef is a magnificently warm and likeable doctor and writer; and he has the best imaginable bedside manner.

    It provides the background needed to understand related drugs currently on the market, as well as drugs yet to be released. In simplifying a complex subject, this text focuses on the essentials of pharmacology. Large print is used to show need-to-know information, and small print is used for nice to know material. At the end of each chapter, a summary of major nursing implications helps in applying the material to real-world situations. This edition includes a new companion CD-ROM featuring NCLEX(R) examination-style review questions, a variety of electronic calculators, and animations depicting drug mechanisms and effects.Uses a prototype drug approach that places a strong emphasis on understanding over memorization - equipping students with the knowledge to learn not only about related drugs currently on the market, but also about those drugs that will be released once the student begins practice.Summaries of Major Nursing Implications at the end of each chapter provide an in-depth look at assessment, implementation, and ongoing evaluations.Utilizes large print for essential information and small print for nice-to-know information to help both faculty and students focus their limited classroom and study time on understanding the essentials.Concise drug summary tables present detailed information on individual drugs, including class, generic and trade names, dosages, routes, and indications.Key Points at the end of each chapter summarize content in a bulleted format to help students review important concepts.Prototype drug discussions employ a clear and consistent format with separate headings for Mechanism of Action; Pharmacologic Effects; Pharmacokinetics; Therapeutic Uses; Adverse Effects; Drug Interactions; and Preparations, Dosage, and Administration.An attractive full-color design adds visual interest, highlights key information, and facilitates student learning.Drugs for Multiple Sclerosis and Drugs for Hemophilia chapters.Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia chapter covers newsworthy drugs such as Viagra and Levitra.Special Interest Topics boxes on current issues in pharmacology, such as Medication-Overuse Headache: Too Much of a Good Thing and Face Time with Botox.Adult Immunization appendix summarizes the latest information on immunizations.Numerous new illustrations show drug mechanisms and effects, and depict topics such as histologic changes in Alzheimer's disease and the movement of drugs following GI absorption.

    Furthermore, the current epidemic of chronic illness demands a new care standard that can break down the existing structural barriers to full resolution. It requires functional medicine. The Evolution of Medicine provides step-by-step instruction for building a successful "community micropractice," one that engages both the patient and practitioner in a therapeutic partnership focused on the body as a whole rather than isolated symptoms. This invaluable handbook will awaken health professionals to exciting new career possibilities. At the same time, it will alleviate the fear of abandoning a conventional medical system that is bad for doctors, patients, and payers, as well as being ineffectual in the treatment of chronic ailments. Welcome to a new world of modern medical care, delivered in a community setting. It's time to embrace the Evolution of Medicine and reignite your love for the art of healing.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    It documents the scale of devastation, the likely causes and consequences, and the resilience with which people faced those pandemics.The book also provides the first comprehensive coverage of the world's greatest demographic disaster ever to descend upon a country in a short period of time - the influenza pandemic in India in 1918, which claimed more lives than all the battle casualties of World War I. And it shows the continuing relevance of learning from those times to tackle contemporary challenges, such as COVID-19.

    But what does the brain have to say about the way we carry our hearts? As technology advances to allow us more focused examination of the intricate dance our brains do with our environment, we can use science to shed new light on humanity’s oldest question, “What is this thing called love?”In each chapter of this lively, edgy adventure through the romantic brain, Kayt Sukel dives into the latest neuroscientific research concerning love and sex (even getting her brain scanned while having an orgasm) and what it really means for the way we approach our relationships. Dirty Minds asks age-old questions such as: What parts of the brain are involved with love? Is there really a “seven-year itch”? Why do good girls like bad boys? Is monogamy practical? How thin is that line between love and hate? Do mothers have a stronger bond with children than their fathers do? How do our childhood experiences affect our emotional control and who is at risk for love addiction? Yet this book offers an entirely fresh approach, explaining all the ways the brain can make or break us in love.

    Here, lead author Joseph Tobin—along with new collaborators Yeh Hsueh and Mayumi Karasawa—revisits his original research to discover how two decades of globalization and sweeping social transformation have affected the way these three cultures educate and care for their youngest pupils. Putting their subjects’ responses into historical perspective, Tobin, Hsueh, and Karasawa analyze the pressures put on schools to evolve and to stay the same, discuss how the teachers adapt to these demands, and examine the patterns and processes of continuity and change in each country. Featuring nearly one hundred stills from the videotapes, Preschool in Three Cultures Revisited artfully and insightfully illustrates the surprising, illuminating, and at times entertaining experiences of four-year-olds—and their teachers—on both sides of the Pacific.

    The authors' accompanying history of both societal and psychiatric standards for women reveals the degree to which the prevailing societal conventions could reinforce the perception that these women were mad.