The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    In this title, the treatment is made easy-to-follow by giving step-by-step derivations, explanations and by avoiding advanced mathematics unfamiliar to students. It covers: math and physics thorough review sections; and worked examples, followed by a practice exercise.

    This practical text reviews basic microbiology and how to approach the pharmacotherapy of a patient with a presumed infection. It also contains concise Drug Class Reviews with an explanation of the characteristics of various classes of antibacterial drugs and antifungal drugs. Antibiotics Simplified, Third Edition simplifies learning infectious disease pharmacotherapy and condenses the many facts that are taught about antibiotics into one quick reference guide. This guide will help students learn the characteristics of antibiotics and why an antibiotic is useful for an indication. With an understanding of the characteristics of the antibiotics, students will be able to make a logical choice to treat an infection more easily. With helpful figures and flow charts, Drug Class Reviews, a Spectra of Activity chart, and an index for reference, this is an ideal handbook for students as well as practicing pharmacists, physicians, and other clinicians!

    Some chapters have been rewritten, making topics such as conjugation and nucleophilic substitution more accessible. Problems are provided which challenge the readers' understanding. read.

    Based on the author’s 27 years of teaching experience, Genetics: A Conceptual Approach, Third Edition, builds upon features that have made past editions so successful:  an engaging writing style; relevant applications; an accessible and instructive art program; an emphasis on problem-solving; and, most importantly, a strong focus on concepts and connections.  To bring these key concepts into sharper focus, Ben Pierce has selectively reduced the amount of detail and has streamlined coverage to focus on essential concepts.

    With the assistance of a co-author, this popular student textbook has now been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course.

    These transitions include the origin of life itself, the first eukaryotic cells, reproduction by sexual means, the appearance ofmulticellular plants and animals, the emergence of cooperation and of animal societies, and the unique language ability of humans. This ambitious book provides the first unified discussion of the full range of these transitions. The authors highlight the similarities between differenttransitions--between the union of replicating molecules to form chromosomes and of cells to form multicellular organisms, for example--and show how understanding one transition sheds light on others. They trace a common theme throughout the history of evolution: after a major transition someentities lose the ability to replicate independently, becoming able to reproduce only as part of a larger whole. The authors investigate this pattern and why selection between entities at a lower level does not disrupt selection at more complex levels. Their explanation encompasses a compellingtheory of the evolution of cooperation at all levels of complexity. Engagingly written and filled with numerous illustrations, this book can be read with enjoyment by anyone with an undergraduate training in biology. It is ideal for advanced discussion groups on evolution and includes accessiblediscussions of a wide range of topics, from molecular biology and linguistics to insect societies.

    Course Lecture Titles1. Biology and BehaviorAn Introduction 2. The Basic Cells of the Nervous System 3. How Two Neurons Communicate 4. Learning and Synaptic Plasticity 5. The Dynamics of Interacting Neurons 6. The Limbic System 7. The Autonomic Nervous System (ANS) 8. The Regulation of Hormones by the Brain 9. The Regulation of the Brain by Hormones 10. The Evolution of Behavior 11. The Evolution of BehaviorSome Examples 12. Cooperation, Competition, and Neuroeconomics 13. What Do Genes Do? Microevolution of Genes 14. What Do Genes Do? Macroevolution of Genes 15. Behavior Genetics 16. Behavior Genetics and Prenatal Environment 17. An Introduction to Ethology 18. Neuroethology 19. The Neurobiology of Aggression I 20. The Neurobiology of Aggression II 21. Hormones and Aggression 22. Early Experience and Aggression 23. Evolution, Aggression, and Cooperation 24. A Summary

    Annotated references are also included.

    Carroll at his very best.--Bill Bryson, author of The Body: A Guide for Occupants From acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the worldWhy is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.Like every other species, we humans are here by accident. But it is shocking just how many things--any of which might never have occurred--had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death.This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

    So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.

    Hansen, PhD. Using this interactive coloring workbook, you can trace arteries, veins, and nerves through their courses and bifurcations...reinforce your understanding of muscle origins and insertions from multiple views and dissection layers...and develop a better understanding of the integration of individual organs in the workings of each body system throughout the human form. Online access to Student Consult-where you'll find the complete contents of the book and much more-further enhances your study and exponentially boosts your reference power. Whether you are taking an anatomy course or just curious about how the body works, let the art of Netter guide you!Provides multiple views, magnifications, and dissection layers that strengthen your understanding of 3-D anatomical relationships.Presents each topic in two-page spreads-with Netter anatomical illustrations accompanied by high-yield information-that gives context to the structures.Features illustrations small enough for quick coloring, but large enough to provide you with important details.Offers tips for coloring key structures that emphasize how a coloring exercise can reinforce learning.Uses Key Points to cover functional and clinical relevance and relationships.Contains tables that review muscle attachments, innervation, action, and blood supply.Features Clinical Notes which highlight the importance of anatomy in medicine.Includes online access to Student Consult where you can search the complete contents of the book, print additional copies of the coloring pages, view completed coloring pages for reference, access Integration Links to bonus content in other Student Consult titles...and much more...to further enhance your study and exponentially boost your reference power.

    The presentation stresses analytical methods, concrete examples, and geometric intuition. A unique feature of the book is its emphasis on applications. These include mechanical vibrations, lasers, biological rhythms, superconducting circuits, insect outbreaks, chemical oscillators, genetic control systems, chaotic waterwheels, and even a technique for using chaos to send secret messages. In each case, the scientific background is explained at an elementary level and closely integrated with mathematical theory.About the Author:Steven Strogatz is in the Center for Applied Mathematics and the Department of Theoretical and Applied Mathematics at Cornell University. Since receiving his Ph.D. from Harvard university in 1986, Professor Strogatz has been honored with several awards, including the E.M. Baker Award for Excellence, the highest teaching award given by MIT.

    It splits the mechanical properties chapter into two separate chapters in order to provide additional and expanded coverage of such topics as fatigue, crack propagation and stress, rupture time, and temperature relationships in creep, to name just a few. In addition, all new topics are accompanied by new problems for a stronger understanding of recent developments in the field.

    Written by an author team, including a Noble Prize winner, this text presents the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the molecular discoveries that have changed the way the field of genetics is viewed.