Just ask biotechnologist Matti Leisola. It all started when a student loaned the Finnish scientist a book criticizing evolutionary theory. Leisola reacted angrily, and set out to defend evolution, but found his efforts raised more questions than they answered. He soon morphed into a full-on Darwin skeptic, even as he was on his way to becoming a leading bio-engineer.Heretic is the story of Leisola's adventures making waves-and many friends and enemies-at major research labs and universities across Europe. Tracing his investigative path, the book draws on Leisola's expertise in molecular biology to show how the evidence points more strongly than ever to the original biotechnologist-a designing intelligence whose skill and reach dwarf those of even our finest bioengineers, and leave blind evolution in the dust.Endorsements "Award-winning Finnish biotechnologist Matti Leisola has written a fascinating account of what happens when a scientist follows the evidence wherever it leads. Leisola's account of how he succeeded should inspire up-and-coming scientists who face the same challenge." Biologist Jonathan Wells, PhD, author of Icons of Evolution and Zombie Science "Scientists, like all other intellectuals, have ideas about what constitutes and what does not constitute reality. However, they are often not aware-and sometimes not ready to admit-that such ideas represent the principles of their philosophy. Leisola and Witt's Heretic is a unique first-hand account of the life-long adventures of a scientist who dared to challenge philosophical principles of colleague scientists. In my opinion, the outcome shows that to many scientists their philosophy is dearer than their science." Biochemist and inventor Branko Kozulic, PhD "This book is an exciting story about how a scientist's relentless search for truth makes him a heretic in the eyes of a cultural community more concerned about prestige than principle." Tapio Puolimatka, PhD and EdD, University of Jyvaskyla, Finland "This book is a personal, strong, and motivated plea for intelligent design (ID) and 'swims against the current' of Darwinian evolution, now generally accepted in scientific circles and society. I personally do not endorse ID, but I am a good friend of the author, whom I also highly respect as a scientist active in academia and in the biotech industry over so many years. Heretic inspires readers to think critically and to open up a civilized discussion on neo-Darwinism versus ID. It covers the science and philosophical parts adequately; it is accessible to a large readership; and statements are underpinned by relevant research and literature data. Its value lies in the author's lifelong engagement and personal crusade to stimulate the public debate among scientists as well as laymen over Darwinism (chance/random mutation and natural selection) versus ID, a vision that Leisola strongly advocates." Dr. Erick J. Vandamme, Emeritus Professor of Bioscience Engineering, Ghent University, Belgium "Matti Leisola has written the exciting story of almost the entire spectrum of aberrant motives, absurd fears, and unreasonable reactions to intelligent design (ID) by evolutionary scientists, clergymen, and church institutions alike, notably during his career as a scientist over the last some forty years. I would add a word on the fears of so many critics that accepting ID also means accepting the dogmata of some 1700 years of church history. ID is thoroughly neutral concerning such topics. So, the reader is invited to carefully check the historical and, what is more, the enormous wealth of scientific data Matti Leisola has presented in the present book: Test them carefully with an open mind and form your own independent opinion!" Dr. Wolf-Ekkehard Lonnig, geneticist, Cologne,

    The book begins with relevant scientific fundamentals and progresses through an exploration of the solar system, stars, galaxies, and cosmology. The Astronomy textbook builds student understanding through the use of relevant analogies, clear and non-technical explanations, and rich illustrations. Mathematics is included in a flexible manner to meet the needs of individual instructors.

    

    Do you want your students to just take psychology or to experience psychology? Laura King's approach to introductory psychology embodies a balanced consideration of functioning behavior as well as dysfunction and a view of psychology as an integrated whole.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    With the stock market sinking and soaring from day to day, retirement plans becoming less certain, and a longer life expectancy in retirement, more people are looking for some control over their investments. If you're one of them, Investing Online For Dummies, 6th Edition might be just what you're looking for. The Internet brings a world of investment resources to your desktop, but how do you find your way through the dizzying array of investment possibilities? The Dummies Way, of course! This book helps you set reasonable expectations, assess your risk tolerance, choose an asset allocation, analyze and select investments, and maximize your financial success. You'll discover how toDetermine how much you can afford to invest Choose an online broker Research, trade, and track investments online Measure the potential return of a stock Maximize your investment knowledge and build a profitable portfolio Buy bonds online Understand options, commodities, and IPOs If you've decided to take control of your investments but don't want to make it your full-time job, Investing Online For Dummies, 6th Edition gives you the important information that will also give you confidence. Completely updated to cover all the new online tools and resources, it even provides some bonus assistance on the companion Web site.

     The Science Book covers every area of science--astronomy, biology, chemistry, geology, math, and physics, and brings the greatest scientific ideas to life with fascinating text, quirky graphics, and pithy quotes.

    Learn the Alphabet and pronunciation as well as useful phrases in 8 categories, such as greetings, travel and directions, making friends to business and emergencies. Download, read and enjoy your vacation like never before.

    Focused on helping students understand and construct proofs and expanding their mathematical maturity, this best-selling text is an accessible introduction to discrete mathematics. Johnsonbaugh's algorithmic approach emphasizes problem-solving techniques. The Seventh Edition reflects user and reviewer feedback on both content and organization.

    It explains all this and much more. It discloses the best time to have a sex change, how to have a virgin birth, when to seduce your sisters or eat your lover. Quirky and brilliant, it takes as its starting point all creatures great and small worried about their bizarre sex lives, and the letters they write to the wise Dr Tatiana, the only agony aunt in all creation with a prodigious knowledge of both natural history and evolutionary biology.

    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

    The book is organized by body system and covers standard scope and sequence requirements. Its lucid text, strategically constructed art, career features, and links to external learning tools address the critical teaching and learning challenges in the course. The web-based version of Anatomy and Physiology also features links to surgical videos, histology, and interactive diagrams.

    Designed primarily for undergraduates, this self-help manual offers straightforward solutions to common problems and an overview of the diversity of writing tasks faced by professional biologists.

    Is the yeti just a phantasm of our imagination, or is it a real creature? A survivor from our own savage ancestry? This is the mystery that Bryan Sykes set out to unlock.Three hair samples from the remote Himalayan kingdom of Bhutan are the cause of the investigation. The hair samples were from the miogi, the Bhutanese yeti, that legendary creature of the high snows that has haunted the imagination of travellers for centuries. Professor Sykes was asked to identify the hairs using DNA analysis. The miogi hairs did not surrender their secrets easily, but eventually two were identified as known species of bear. The third remained a mystery. Ten years later two scientific developments caused the migoi to enter Professor Sykes' thoughts again. The first, a purely technical improvement, meant that it was now possible to get a very good DNA signal from a single hair. The second development came from the surprising conclusion of an article published in 2010. This paper contained the details of the DNA sequence from another human species, Homo neanderthalensis, the Neanderthals, widely thought to be extinct. One of the many theories to account for the yeti legend is that there were small groups of Neanderthals that had managed to survive until recent times, or maybe even until the present day. If so, would it be possible to detect recent interbreeding between our own species and Neanderthals in the genomes of indigenous people living in remote regions. Locations where the yeti legends are strongest and the sightings most numerous?Professor Sykes set a goal to locate and analyse as many hair samples as possible, with links the yeti. In doing so Professor Sykes found himself entering a strange world of mystery and sensationalism, fraud and obsession and even the supernatural. Protected by the ruthless vigour of genetic analysis he was able to listen to the stories of the yeti without having to form an opinion. The only opinion that mattered was the DNA.Two years on the project is almost complete, and there have been some surprising and significant discoveries. The yeti remains an enigma. There is something out there. But what?

    The new edition maintains the scope and expertise that made the book so popular while incorporating the latest research and updating the exquisite program of drawings.