Harlen Bretz walked the dry scabland channels of eastern Washington in the 1920s, it dawned on him that he was viewing a landscape sculpted by water. Lots of water. A flood of catastrophic proportions. Glacial Lake Missoula and Its Humongous Floods tells the gripping tale of a huge Ice Age lake that drained suddenly--not just once but repeatedly--and reshaped the landscape of the Northwest. The narrative follows the path of the floodwaters as they raged from western Montana across the Idaho Panhandle, then scoured through eastern Washington and down the Columbia Gorge to the Pacific Ocean. This is also the story of geologists grappling with scientific controversy--"of how personalities, pride, and prejudice sometimes superseded scientific evidence."

    We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

    Updated and enhanced, it provides insight on contemporary research and trends in oral histology, embryology, physiology, oral biology, and postnatal growth and development essential to your success in dentistry!Topics for Consideration boxes present expert perspectives on current trends and encourage additional research.Content outlines provide quick reference to specific topics within chapters.Logical organization enhances your understanding of chapter content and helps you review more effectively.Up-to-date recommended readings direct you to additional sources of relevant information.Concise, user-friendly writing style makes complex concepts easier to grasp.Companion CD includes over 300 multiple choice questions and over 100 labeling exercises that help you assess your comprehension and prepare for Part I of the board exam.Hundreds of full-color illustrations visually acquaint you with the oral structures and microscopic anatomy you'll encounter in dental care.Electronic image collection included on the companion CD is now in full-color, giving you clear, vibrant visual references for convenient study and review.

    Completely revised and updated, the 7th Edition consistently emphasizes the clinical aspects by using a wealth of case studies, clinical correlations, and hundreds of outstanding illustrations.Features a wealth of clinical case studies-and hundreds of color photgraphs-enabling readers to relate what they are learning to clinical practice.Contains a chapter on birth defects that can be used as a mini textbook on the subject.Integrates the molecular aspects of embryonic development, including information on stem cells - homeobox genes - gamete formation - regulation control and the molecules/receptors involved - gene activity and expression - and more.Includes illustrations of new diagnostic procedures, including sonographs, MRIs, electron micrographs, 3D images, and clinical photographs.Includes the new terminology developed for embryology-the Terminoligica Embryologica.Presents completely revised and updated Clinically Oriented Questions and Answers based on the current requirements of the USMLE Step 1.Has been reviewed by leading geneticists and pediatricians to ensure that all of the information reflects the realities of clinical practice.

    They impact thousands upon thousands of metabolic reactions inside the human body. But calculating the specific influence of each of these chemicals isn’t nearly sufficient to explain the effect of the apple as a whole. Because almost every chemical can affect every other chemical, there is an almost infinite number of possible biological consequences.And that’s just from an apple.Nutritional science, long stuck in a reductionist mindset, is at the cusp of a revolution. The traditional "gold standard” of nutrition research has been to study one chemical at a time in an attempt to determine its particular impact on the human body. These sorts of studies are helpful to food companies trying to prove there is a chemical in milk or pre-packaged dinners that is "good” for us, but they provide little insight into the complexity of what actually happens in our bodies or how those chemicals contribute to our health.In The China Study, T. Colin Campbell (alongside his son, Thomas M. Campbell) revolutionized the way we think about our food with the evidence that a whole food, plant-based diet is the healthiest way to eat. Now, in Whole, he explains the science behind that evidence, the ways our current scientific paradigm ignores the fascinating complexity of the human body, and why, if we have such overwhelming evidence that everything we think we know about nutrition is wrong, our eating habits haven’t changed.Whole is an eye-opening, paradigm-changing journey through cutting-edge thinking on nutrition, a scientific tour de force with powerful implications for our health and for our world.

    Known for its carefully developed, thoroughly integrated, step-by-step approach to problem solving, General Chemistry helps students master quantitative skills and build a lasting conceptual understanding of key chemical concepts. The Ninth Edition retains this hallmark approach and builds upon the conceptual focus through key new features and revisions.

    Chapters parallel most standard pathology texts and each chapter ends with a review test. Topics covered include general and basic pathology, major concepts of disease processes, and systemic pathology surveying principal disorders of each organ system. A comprehensive examination at the end of the book contains 500 USMLE-format questions. USMLE questions have all been updated to current USMLE format.The text is written in outline format for effective review. Icons indicate high-yield information that correlates with key pathology concepts.

    Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer's outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer's brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

    Coverage includes basic procedures such as spays, castrations, and declaws, as well as more advanced surgeries that might be referred to specialists such as craniotomy, ventral slots, and lung lobectomy. Discussions of general surgical procedures include sterile technique, surgical instrumentation, suturing, preoperative care, and antibiotic use. Key sections provide clinically relevant coverage of soft tissue surgery, orthopedic surgery, and neurosurgery.Over 1500 full color illustrations provide exceptionally clear representations of anatomy and currently accepted surgical techniques, including approaches and closure.Over 600 full color photographs and radiographs offer clear images of specific disorders, diseases, and procedures.Information on the most efficient and cost-saving sterilization techniques including scrubless and waterless preparation solutions.General considerations and clinically relevant pathophysiology sections provide practical information for case management.Step-by-step instructions for surgical techniques are presented in italicized blue type for quick and easy reference.Special icons identify advanced procedures that should be referred to an experienced surgeon or specialist.Color-coded tables and boxes call attention to specific data, offering at-a-glance access to key information such as drug dosages, clinical signs, and analgesic protocols.Anesthesia Protocols provide quick and easy access to recommendations for anesthetizing animals with particular diseases or disorders.A new chapter on Fundamentals of Physical Rehabilitation details the basics of physical rehabilitation for practitioners who want to integrate physical therapy into practice.A new chapter on Principles of Minimally Invasive Surgery that describes the principles of performing surgery with the least instrumentation possible, including instrument selection and care and basic techniques.A new chapter on Surgery of the Eye that discusses diseases and disorders of the eye, their medical management, and corrective surgical procedures.Expanded coverage of perioperative multimodal analgesic therapy.Updated coverage of arthroscopy, canine elbow dysplasia, joint replacement, and management of osteoarthritis.The latest information on state-of-the-art radiologic techniques.

    It has become known for its engaging writing style, instructional art program and focus on active learning. We are so excited to offer a robust learning program with student-focused learning activities, allowing the student to manage their learning while you easily manage their assessment. Detailed reports show how your assignments measure various learning objectives from the book (or input your own!), levels of Bloom's Taxonomy or other categories, and how your students are doing. The Cowan Learning program will save you time and improve your student's success in this course.

    Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    Psychiatrist and psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they’ve transformed - people whose mental limitations or brain damage were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

    The problem is that an overhydrated athlete is at a performance disadvantage and at risk of exercise-associated hyponatremia (EAH)--a potentially fatal condition.Dr. Tim Noakes takes you inside the science of athlete hydration for a fascinating look at the human body's need for water and how it uses the liquids it ingests. He also chronicles the shaky research that reported findings contrary to results in nearly all of Noakes' extensive and since-confirmed studies.In Waterlogged, Noakes sets the record straight, exposing the myths surrounding dehydration and presenting up-to-date hydration guidelines for endurance sport and prolonged training activities. Enough with oversold sports drinks and obsessing over water consumption before, during, and after every workout, he says. Time for the facts--and the prevention of any more needless fatalities.

    But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    This trusted classic delivers comprehensive coverage of the field's must-know basic science and clinical topics in a clear, easy-to-understand presentation. Indispensable for coursework, exam review, and as a clinical refresher, this trusted text has been extensively updated to reflect the latest research and developments.Here's why Clinical Anesthesiology is the best anesthesiology resource:NEW full-color presentationNEW chapters on the most pertinent topics in anesthesiology, including anesthesia outside of the operating room and a revamped peripheral nerve blocks chapter that details ultrasound-guided regional anesthesiaUp-to-date discussion of all relevant areas within anesthesiology, including equipment, pharmacology, regional anesthesia, pathophysiology, pain management, and critical careCase discussions promote application of the concepts to real-world practiceNumerous tables and figures encapsulate important information and facilitate memorization