Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns.The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

    In the past, discoveries often had to wait for the rise of the next generation to see questions in a new light and let go of old truisms. Today, in a world that is defined by a rapid rate of change, staying on the cutting edge has as much to do with shedding outdated notions as adopting new ones. In this spirit, John Brockman, publisher of the online salon Edge.org ("the world's smartest website"—The Guardian), asked 175 of the world's most influential scientists, economists, artists, and philosophers: What scientific idea is ready for retirement?Jared Diamond explores the diverse ways that new ideas emerge * Nassim Nicholas Taleb takes down the standard deviation * Richard Thaler and novelist Ian McEwan reveal the usefulness of "bad" ideas * Steven Pinker dismantles the working theory of human behavior * Richard Dawkins renounces essentialism * Sherry Turkle reevaluates our expectations of artificial intelligence * Physicist Andrei Linde suggests that our universe and its laws may not be as unique as we think * Martin Rees explains why scientific understanding is a limitless goal * Alan Guth rethinks the origins of the universe * Sam Harris argues that our definition of science is too narrow * Nobel Prize winner Frank Wilczek disputes the division between mind and matter * Lawrence Krauss challenges the notion that the laws of physics were preordained * plus contributions from Daniel Goleman, Mihaly Csikszentmihalyi, Nicholas Carr, Rebecca Newberger Goldstein, Matt Ridley, Stewart Brand, Sean Carroll, Daniel C. Dennett, Helen Fisher, Douglas Rushkoff, Lee Smolin, Kevin Kelly, Freeman Dyson, and others.

    Included are step-by-step instructions on how to carry out Bayesian data analyses.Download Link : readbux.com/download?i=0124058884            0124058884 Doing Bayesian Data Analysis: A Tutorial with R, JAGS, and Stan PDF by John Kruschke

    

    It provides comprehensive coverage of the subject from basic principles to state-of-art concepts and applications. The objective is to give the reader a sound understanding of the principles and the basis for applying them in a variety of both product and nonproduct situations. While statistical techniques are emphasized throughout, the book has a strong engineering and management orientation. Guidelines are given throughout the book for selecting the proper type of statistical technique to use in a wide variety of product and nonproduct situations. By presenting theory, and supporting the theory with clear and relevant examples, Montgomery helps the reader to understand the big picture of important concepts. Updated to reflect contemporary practice and provide more information on management aspects of quality improvement.

    For real.If you're like most people, geometry is a sterile and dimly remembered exercise you gladly left behind in the dust of ninth grade, along with your braces and active romantic interest in pop singers. If you recall any of it, it's plodding through a series of miniscule steps only to prove some fact about triangles that was obvious to you in the first place. That's not geometry. Okay, it is geometry, but only a tiny part, which has as much to do with geometry in all its flush modern richness as conjugating a verb has to do with a great novel.Shape reveals the geometry underneath some of the most important scientific, political, and philosophical problems we face. Geometry asks: Where are things? Which things are near each other? How can you get from one thing to another thing? Those are important questions. The word "geometry," from the Greek for "measuring the world." If anything, that's an undersell. Geometry doesn't just measure the world—it explains it. Shape shows us how.

    Our intimate connection with the world, skin protects us while advertising our health, our identity, and our individuality. This dazzling synthetic overview, written with a poetic touch and taking many intriguing side excursions, is a complete guidebook to the pliable covering that makes us who we are. Skin: A Natural History celebrates the evolution of three unique attributes of human skin: its naked sweatiness, its distinctive sepia rainbow of colors, and its remarkable range of decorations. Jablonski begins with a look at skin's structure and functions and then tours its three-hundred-million-year evolution, delving into such topics as the importance of touch and how the skin reflects and affects emotions. She examines the modern human obsession with age-related changes in skin, especially wrinkles. She then turns to skin as a canvas for self-expression, exploring our use of cosmetics, body paint, tattooing, and scarification. Skin: A Natural History places the rich cultural canvas of skin within its broader biological context for the first time, and the result is a tremendously engaging look at ourselves.

    However, according to Hofstadter, the formal system that underlies all mental activity transcends the system that supports it. If life can grow out of the formal chemical substrate of the cell, if consciousness can emerge out of a formal system of firing neurons, then so too will computers attain human intelligence. Gödel, Escher, Bach is a wonderful exploration of fascinating ideas at the heart of cognitive science: meaning, reduction, recursion, and much more.

    It is also a lucid exposition of the nature and methods of genuine science. The book begins with a concise introduction to evolutionary theory for non-scientists and closes with a rebuttal of the charge that this theory undermines religious and moral values. It will astonish many readers that this case must still be made in the 1980s, but since it must, Philip Kitcher makes it irresistibly and forcefully.Not long ago, a federal court struck down an Arkansas law requiring that scientific Creationism be taught in high school science classes. Contemporary Creationists may have lost one legal battle, but their cause continues to thrive. Their efforts are directed not only at state legislatures but at local school boards and textbook publishers. As Kitcher argues in this rigorous but highly readable book, the integrity of science is under attack. The methods of inquiry used in evolutionary biology are those which are used throughout the sciences. Moreover, modern biology is intertwined with other fields of science--physics, chemistry, astronomy, and geology. Creationists hope to persuade the public that education in science should be torn apart to make room for a literal reading of Genesis.Abusing Science refutes the popular complaint that the scientific establishment is dogmatic and intolerant, denying academic freedom to the unorthodox. It examines Creationist claims seriously and systematically, one by one, showing clearly just why they are at best misguided, at worst ludicrous.

    It remains an elementary and non-mathematical introduction to molecular spectroscopy that emphasizes the overall unity of the subject and offers a pictorial perception rather than a mathematical description of the principles of spectroscopy.

    The first abnormal psychology book to present a thoroughly integrated multicultural perspective--based on the authors' view that cross-cultural comparisons can greatly enhance the understanding of disorders--the text provides extensive coverage and integration of multicultural models, explanations, and concepts. The book also helps you gain an understanding of abnormal behavior as scientific and clinical endeavors, while providing insight into the tools that mental health professionals use to study and treat disorders.

    Stephen Hawking’s phenomenal, multimillion-copy bestseller, A Brief History of Time, introduced the ideas of this brilliant theoretical physicist to readers all over the world.Now, in a major publishing event, Hawking returns with a lavishly illustrated sequel that unravels the mysteries of the major breakthroughs that have occurred in the years since the release of his acclaimed first book.

    The book takes us from the Greeks' earliest scientific observations through Einstein and beyond in an inspiring celebration of human curiosity. It ends with the quest for the Higgs boson, nicknamed the God Particle, which scientists hypothesize will help unlock the last secrets of the subatomic universe. With a new preface by Lederman, The God Particle will leave you marveling at our continuing pursuit of the infinitesimal.

    

    In The Anatomy of Violence, Raine dissects the criminal mind with a fascinating, readable, and far-reaching scientific journey into the body of evidence that reveals the brain to be a key culprit in crime causation.  Raine documents from genetic research that the seeds of sin are sown early in life, giving rise to abnormal physiological functioning that cultivates crime. Drawing on classical case studies of well-known killers in history—including Richard Speck, Ted Kaczynski, and Henry Lee Lucas—Raine illustrates how impairments to brain areas controlling our ability to experience fear, make good decisions, and feel guilt predispose us to violence. He contends that killers can actually be coldhearted: something as simple as a low resting heart rate can give rise to violence. But arguing that biology is not destiny, he also sketches out provocative new biosocial treatment approaches that can change the brain and prevent violence.  Finally, Raine tackles the thorny legal and ethical dilemmas posed by his research, visualizing a futuristic brave new world where our increasing ability to identify violent offenders early in life might shape crime-prevention policies, for good and bad. Will we sacrifice our notions of privacy and civil rights to identify children as potential killers in the hopes of helping both offenders and victims? How should we punish individuals with little to no control over their violent behavior? And should parenting require a license? The Anatomy of Violence offers a revolutionary appraisal of our understanding of criminal offending, while also raising provocative questions that challenge our core human values of free will, responsibility, and punishment.From the Hardcover edition.