Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

    

    It offers complete coverage of the basics of hematologic morphology, including examination of the peripheral blood smear, basic maturation of the blood cell lines, and discussions of a variety of clinical disorders. Over 400 photomicrographs, schematic diagrams, and electron micrographs visually clarify hematology from normal cell maturation to the development of various pathologies.Normal Newborn Peripheral Blood Morphology chapter covers the unique normal cells found in neonatal blood.A variety of high-quality schematic diagrams, photomicrographs, and electron micrographs visually reinforce your understanding of hematologic cellular morphology.Spiral binding and compact size make this book easy to use in a laboratory setting.Coverage of common cytochemical stains, along with a summary chart for interpretation, aids in classifying malignant and benign leukoproliferative disorders.Morphologic abnormalities are presented in chapters on erythrocytes and leukocytes, along with a schematic description of each cell, to provide correlations to various disease states.Body Fluids chapter covers the other fluids found in the body besides blood, using images from cytocentrifuged specimens.Updated information on the subtypes of chronic lymphocytic leukemia (CLL) helps you recognize variant forms of CLL you may encounter in the lab.

    The role reversal involved is emotionally and intellectually demanding, and many caregivers find themselves unprepared to undertake such a difficult task. In Trading Places: Becoming My Mother’s Mother, author Sandra Bullock Smith shares her personal experiences spending ten years caring for her ailing mother. This heartfelt look at the trials and tribulations of that decade offers powerful insight and encouragement for anyone entering into a similar period of life. Smith’s touching stories share the heartbreaking, and sometimes comical, moments she experienced while providing assistance to her aging parent—and how they mirrored similar events from her own childhood. In a very real sense, the two women traded places. Smith found herself uttering phrases she heard all too often as a child, such as, “Don’t give your food to the dog” and, “You’ve had enough sugar today.” Smith began jotting down the things she said, and thus this charming book was born. Filled with respect, compassion, and love, this uplifting and amusing memoir is for anyone involved in elder care or who may face the role in the future.

    Why, specifically?”“I like to build things.”As of the time of writing, more than ten million copies of E L James’ “Fifty Shades of Grey” have been sold worldwide. Whether you find this notion inspiring or terrifying, there’s no escaping the fact that, as literary events go, “Fifty Shades of Grey” is at least...significant. And books that are...significant...deserve to be subjected to thorough critical and textual analysis. By taking it apart into teeny tiny small pieces and put those pieces under a spiteful and mean-spirited microscope, we may all just learn something about the elusive nature of the bestseller,“Lighter Shades of Grey” is a chapter-by-chapter dissection of “Fifty Shades of Grey”, cataloguing unusual leaps of logic, surprising deductions, exciting exchanges of dialogue, recurrent motifs and stand-out moments, that will allow you to better appreciate / enjoyably ruin for others the “Fifty Shades” experience. It also provides definitive answers to questions such as “How often does Ana say ’oh my’?”, “How often do people’s mouths fall open in surprise?” and “Is Christian Grey a diagnosable psychopath?”Building on the viral hit blog-entry, “Fifty Things That Annoy Me About Fifty Shades Of Grey”, “Lighter Shades of Grey” is the perfect snarky companion to this year’s most inexplicable blockbuster. (Approximately 31,000 words; 30 pictures)

    But then she didn't count on having a gypsy wedding...It's rare for a 'gorger', or non-traveller, to marry into the gypsy community. But after a shocking childhood tragedy, Sam found the comfort she needed from an unxpected source - Patrick and his family of travellers.Gypsy Bride is the heartwarming true story of how an ordinary girl finds herself discovering an extraordinary world. A place where 'grabbing' is a sign a boy fancies you, six-year-olds get spray tans, and christenings, weddings and funerals are jaw-droppingly flamboyant.This love story is more than boy meets girl. It's about a girl who falls in love with a whole race of people and their wonderful ways.

    I also hope that it will serve as a useful reference too for the many workers engaged in one type of solid state research activity or another, who may be without formal training in the subject.

    Personal stories combine with staff experiences to reveal hidden truths about the operating room and illustrate the quirky, strange, and bizarre occurrences that shape a regular hospital day. Answering questions such as What do doctors talk about during surgery? If a surgical instrument falls to the floor, is the five-second rule observed? and Is real life just like ER, Grey’s Anatomy, and House?, this is a must-read for the curiosity seeker and anyone who has or will be on the operating-room table.

    It gives clear descriptions of linear systems and uses mathematics not only to prove axiomatic theory, but also to enhance physical and intuitive understanding.

    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.

    Paradoxical portraits of seven neurological patients, including a surgeon consumed by the compulsive tics of Tourette's syndrome unless he is operating; an artist who loses all sense of color in a car accident, but finds new creative power in black & white; & others.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Kinesiology of the Musculoskeletal System is the most comprehensive, research-based, reader-friendly text on kinesiology ever published. Beautifully and abundantly illustrated in two-color, this dynamic, accessible resource presents complex scientific information in an approach designed to draw the reader in and explore the fundamental principles of kinesiology of the trunk and extremities as well as in relation to joints, muscles, and biomechanics.Comprehensive coverage - not only of kinesiology of the trunk and extremitites, but also of the underlaying principles of kinesiology with respect to joints, muscles and biomechanics - explains the 'why?' as well as the 'how?'A definitive chapter on the kinesiology of human gait!Clear and reader-friendly, which is great for study and revision for students of all levelsSpecial Focus boxes throughout the text provide abundant clinical examples and gives the students a chance to probe deeper into the topicTopics at a Glanceat the beginning of each chapter, allow students with less time to quickly locate the essential informationOver 550 superb line-drawings - making difficult kinesiologic concepts easier to graspAppendices include glossary of key terms - a handy reference toolThe author has many years of experience in physical therapy - specifically kinesiology - and is a teacher, clinician and researcher.

    The key to every biological problem must finally be sought in the cell, for every living organism is, or at sometime has been, a cell."