But the story of the vaccine has a dark side, one that has never been fully told before...Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans.But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.

    Today we can see a recreation of the making of the Laetoli footprints at the American Museum of Natural History, in a stunning diorama which depicts two of our human forebears walking side by side through a snowy landscape of volcanic ash. But how do we know what these three-million-year-old relatives looked like? How have we reconstructed the eons-long journey from our first ancient steps to where we stand today? In short, how do we know what we think we know about human evolution? In The Fossil Trail, Ian Tattersall, the head of the Anthropology Department at the American Museum of Natural History, takes us on a sweeping tour of the study of human evolution, offering a colorful history of fossil discoveries and a revealing insider's look at how these finds have been interpreted--and misinterpreted--through time. All the major figures and discoveries are here. We meet Lamarck and Cuvier and Darwin (we learn that Darwin's theory of evolution, though a bombshell, was very congenial to a Victorian ethos of progress), right up to modern theorists such as Niles Eldredge and Stephen Jay Gould. Tattersall describes Dubois's work in Java, the many discoveries in South Africa by pioneers such as Raymond Dart and Robert Broom, Louis and Mary Leakey's work at Olduvai Gorge, Don Johanson's famous discovery of Lucy (a 3.4 million-year-old female hominid, some 40% complete), and the more recent discovery of the Turkana Boy, even more complete than Lucy, and remarkably similar to modern human skeletons. He discusses the many techniques available to analyze finds, from fluorine analysis (developed in the 1950s, it exposed Piltdown as a hoax) and radiocarbon dating to such modern techniques as electron spin resonance and the analysis of human mitochondrial DNA. He gives us a succinct picture of what we presently think our family tree looks like, with at least three genera and perhaps a dozen species through time (though he warns that this greatly underestimates the actual diversity of hominids over the past two million or so years). And he paints a vivid, insider's portrait of paleoanthropology, the dogged work in the broiling sun, searching for a tooth, or a fractured corner of bone, amid stone litter and shadows, with no guarantee of ever finding anything. And perhaps most important, Tattersall looks at all these great researchers and discoveries within the context of their social and scientific milleu, to reveal the insidious ways that the received wisdom can shape how we interpret fossil findings, that what we expect to find colors our understanding of what we do find. Refreshingly opinionated and vividly narrated, The Fossil Trail is the only book available to general readers that offers a full history of our study of human evolution. A fascinating story with intriguing turns along the way, this well-illustrated volume is essential reading for anyone curious about our human origins.

    Between 1953 and 1966 he made and led a revolution in biology by discovering, quite literally, the secret of life: the digital cipher at the heart of heredity that distinguishes living from non-living things -- the genetic code. His own discoveries -- though he always worked with one other partner and did much of his thinking in conversation -- include not only the double helix but the whole mechanism of protein synthesis, the three-letter nature of the code, and much of the code itself.Matt Ridley's biography traces Crick's life from middle-class mediocrity in the English Midlands, through a lackluster education and six years designing magnetic mines for the Royal Navy, to his leap into biology at the age of thirty-one. While at Cambridge, he suddenly began to display the unique visual imagination and intense tenacity of thought that would allow him to see the solutions to several great scientific conundrums -- and to see them long before most biologists had even conceived of the problems. Having set out to determine what makes living creatures alive and having succeeded, he immigrated at age sixty to California and turned his attention to the second question that had fascinated him since his youth: What makes conscious creatures conscious? Time ran out before he could find the answer.

    In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

    Illustrated with hundreds of photographs, this visual documentary of Michael Jackson presents all the facts and includes his records, concerts, videos and awards, his public appearances and performances, memorabilia and records you never knew existed.

    The easy kind, practiced by ants, shrimp, Welsh corgis -- and us -- is innate. What innate calculating skills do we humans have? Leaving aside built-in mathematics, such as the visual system, ordinary people do just fine when faced with mathematical tasks in the course of the day. Yet when they are confronted with the same tasks presented as "math," their accuracy often drops. But if we have innate mathematical ability, why do we have to teach math and why do most of us find it so hard to learn? Are there tricks or strategies that the ordinary person can do to improve mathematical ability? Can we improve our math skills by learning from dogs, cats, and other creatures that "do math"? The answer to each of these questions is a qualified yes. All these examples of animal math suggest that if we want to do better in the formal kind of math, we should see how it arises from natural mathematics. From NPR's "Math Guy" -- The Math Instinct will provide even the most number-phobic among us with confidence in our own mathematical abilities.

    The newly revised Fifth Edition has been significantly updated throughout and features substantially revised art and Running Problems in the book and on the reader Companion Website. Recognized as an extraordinary educator and active learning enthusiast, Dr. Silverthorn incorporates time-tested classroom techniques throughout the book and presents thorough, up-to-date coverage of new scientific discoveries, biotechnology techniques, and treatments of disorders. Dr. Silverthorn also co-authored the accompanying Student Workbook and Instructor Manual, ensuring that these ancillaries reinforce the pedagogical approach of the book.The Fifth Edition includes access to Interactive Physiology(R) 10-System Suite (IP-10), PhysioEx(TM) 8.0, A&P Flix animations in 3D, and The Physiology Place Companion Website. Key Topics: Introduction to Physiology, Molecular Interactions, Compartmentation: Cells and Tissues, Energy and Cellular Metabolism, Membrane Dynamics, Communication, Integration, Homeostasis, Introduction to the Endocrine System, Neurons: Cellular and Network Properties, The Central Nervous System, Sensory Physiology, Efferent Division: Autonomic and Somatic Motor Control, Muscles, Integrative Physiology I: Control of Body Movement, Cardiovascular Physiology, Blood Flow and the Control of Blood Pressure, Blood, Mechanics of Breathing, Gas Exchange and Transport, The Kidneys, Integrative Physiology II: Fluid and Electrolyte Balance, Digestion, Energy Balance and Metabolism, Endocrine Control of Growth and Metabolism, The Immune System, Integrative Physiology III: Exercise, Reproduction and DevelopmentMarket: Intended for those interested in learning the basics of human physiology

    The largest of them, the Siberian tiger, is today almost entirely confined to the little-populated Russian Far East, a region that may offer the species' best hope for survival. But the implosion of the Soviet Union intensified poaching and habitat depredation, prompting a group of Russian researchers and U.S. wildlife biologists led by Maurice Hornocker to join forces to stave off extinction.Peter Matthiessen brings to the Siberian tiger the deep knowledge of and feeling for the natural world that have made classics of his previous books. Accompanying researchers into the field, he allows the reader to participate vicariously in the battle for the tiger's future. Along the way, he tells how the species evolved and evokes its crucial, often totemic role in human cultures and mythologies. He has made of the tiger's dilemma a drama-underscored by Hornocker's one-of-a-kind photographs-that conveys powerfully what a loss to our collective imagination the disappearance of these great cats would be.

    A. Foley, Antiquity), The Human Career has proved to be an indispensable tool in teaching human origins since its publication in 1989. This substantially revised edition retains Richard Klein's innovative approach and incorporates new findings from the past decade.The Human Career chronicles the evolution of people from the earliest primates through the emergence of fully modern humans within the past 200,000 years. Its comprehensive treatment stresses recent advances in knowledge, including, for example, ever more abundant evidence that fully modern humans originated in Africa and spread from there, replacing the Neanderthals in Europe and equally archaic people in Asia. With its coverage of both the fossil record and the archeological record over the 2.5 million years for which both are available, Klein emphasizes that human morphology and behavior evolved together. Throughout the text, Klein presents evidence for alternative points of view, but also does not hesitate to take a position.In addition to outlining the broad pattern of human evolution, The Human Career details the kinds of data that support this pattern, including information on archeological sites, artifacts, fossils, and methods for establishing dates in geological time. With abundant references and hundreds of illustrations, charts, and diagrams, this new edition is unparalleled in its usefulness for teaching human evolution.

    At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    Hundreds of thousands of pianos are bought and sold each year, yet most people buy a piano with only the vaguest idea of what to look for as they make this major purchase. The Piano Book evaluates and compares every brand and style of piano sold in the United States. There is information on piano moving and storage, inspecting individual new and used pianos, the special market for Steinways, and sales gimmicks to watch out for. An annual supplement, sold separately, lists current prices for more than 2,500 new piano models.

    It provides up to date information on structural properties, the processing of materials and their applications.

    Constable Wood was a disaster waiting to happen. He was the sort of cop who was happier helping little old ladies across the street (even when they were quite content where they were) than pursuing the perpetrators of dreadful deeds. But if he failed to strike fear into the hearts of the criminal underworld, his superiors had a real problem on their hands. Never before had they been forced to deal with such a well-meaning but accident-prone officer and they hoped, fervently, never to see his like again. From his early encounters with a less-than-impressed public, through the terrifying days of the Springbok Tour riots, to the gradual realisation that perhaps he wasn’t cut out for life on the beat, this is the hilarious story of a young cop who created a severe disturbance in the force.

    Thus, the literature on speciation, as well as the number of researchers and students working in this area, has grown explosively. Despite thesedevelopments, there has been no book-length treatment of speciation in many years. As a result, both the seasoned scholar and the newcomer to evolutionary biology had no ready guide to the recent literature on speciation--a body of work that is enormous, scattered, and increasingly technical.Although several excellent symposium volumes have recently appeared, these collections do not provide a unified, critical, and up-to-date overview of the field. Speciation is designed to fill this gap.Aimed at professional biologists, graduate students, and advanced undergraduates, Speciation covers both plants and animals (the first book on this subject to do so), and deals with all relevant areas of research, including biogeography, field work, systematics, theory, and genetic and molecularstudies. It gives special emphasis to topics that are either controversial or the subject of active research, including sympatric speciation, reinforcement, the role of hybridization in speciation, the search for genes causing reproductive isolation, and mounting evidence for the role of natural andsexual selection in the origin of species. The authors do not hesitate to take stands on these and other controversial issues. This critical and scholarly book will be invaluable to researchers in evolutionary biology and is also ideal for a graduate-level course on speciation.

    The authors bring to life Darwin's reckless student days in Cambridge, his epic five-year voyage on the Beagle, and his grueling struggle to develop his theory of evolution.Adrian Desmond and James Moore's gripping narrative reveals the great personal cost to Darwin of pursuing inflammatory truths—telling the whole story of how he came to his epoch-making conclusions.