Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    For example, the common cold, measles, chicken pox, herpes and mumps, rubella, as well as less familiar examples, such as rabies, breakbone’ fever, hemorrhagic fevers like Ebola, and virus-induced cancers. Along the way, readers will learn about the behaviors and ultimate goals of viruses, gaining a deeper understanding of their importance in relation to the origins and the evolution of life, as well as they ways viruses have changed us at the most intimate level, to help make us quintessentially human.

    Gerber, bestselling author of The E-Myth Revisited shares his powerful insights to lead independent physicians to successful practices and enriched lives.Michael Gerber has dedicated much of his professional life to the study of entrepreneurship and business dynamics. His E-Myth Academy is renown in the entrepreneurial world for its business insight and guidance as well as its inspirational advice.In the E-Myth Physician, bestselling author Gerber returns to his roots in order to provide indispensable advice to doctors who own and run their own practices. Gerber provides excellent business insights into topics such as streamlining systems, effective small-business management practices, healthy patient relations and managing cash flow, all with the goal of freeing physicians from the daily grind of running a business and leading them to a happier and more productive life while doing the job they love - practising medicine.

    We all hurt and need true, lasting healing. The trouble, according to bestselling author Andrew Farley and Bart Millard, lead singer of MercyMe, is that we don't know where to find it.Inspired by MercyMe's #1 hit song of the same name, The Hurt & The Healer reveals exactly how God can be the gentle healer of all our hurts. Writing from the pain they've experienced in their lives, Millard and Farley reveal how their own struggles caused them to feel they had disappointed God. Through their biblical guidance, readers will see that God wants them to be open and honest about their pain. Only then can they discover how to exchange destructive thinking patterns for God's view of them and watch as God's perfect love casts away all their fears.

    A full pharmacopoeia of natural remedies for common ailments and injuries, it also contains sections on homeopathy for children and pets.It covers the history and use of homeopathy in the home. It covers a wide variety of aspects of illness and homeopathy and chapters cover the following:What is Homeopathy?A Homeopathic Physician at WorkYour Home Remedy KitWhat to Do for AccidentsIn Case of EmergencyHow to Prevent and Treat Colds, Coughs and EarachesRemedies for Stomach and Bowel ProblemsA Happier Baby with Homeopathic CareYour Growing ChildWhat Homeopathy Can Do for WomenKeeping Your Pets HealthyRemedies and their AbbreviationsMini-RepertoryMateria Medica

    They had been on the hamster wheel of diets from long before they met. From the time of their wedding in 2003, they ate their way through a decade plagued by massive weight gain until 2014, at which point they topped out at well over 500 pounds combined. First Ryan began a weight loss effort, then Kim followed suit, eventually leading them both to intermittent fasting as outlined in Gin Stephens’ “Delay, Don’t Deny: Living an Intermittent Fasting Lifestyle.” At this point, Ryan and Kim have lost a collective 220 pounds. The journey transformed not only their connection to food, but to themselves and to each other. Their lives are filled with a peaceful joy that they hope to share with others. The Smiths specifically hope to reach couples who feel their separate issues with food are magnified in the context of their relationship. They run a busy Facebook support group called Fasting, Feasting, FREEDOM with Kim & Ryan. Updates about their lives can always be found at www.fastingfeastingfreedom.com.

    We're all looking for new ways of thinking that can bring about real solutions to modern problems, from the pursuit of inner serenity to solving world conflicts. In Do You QuantumThink? author Dianne Collins shares her ingenious discovery that reveals a critical missing link to make sense of our changing times. Her discovery provides us with the understanding and methodology to rise above problems of today by laying the foundation for an entirely new way to think.Part science, part philosophy, part spirituality, Do You QuantumThink? draws on a wide spectrum of sources, from cutting edge innovations in the sciences to the insights of the world's greatest spiritual leaders. This book will make you laugh, free you from limiting ideas, and introduce you to the most advanced principles and practical methods for living. Do You QuantumThink? will rock your world in the best of ways as you experience one revelation after another.

    Siracusa's overview, wrap-up, and critique of everything new in OS X 10.10 Yosemite.

    The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    Great for the newest member and seasoned practitioners. --sgi-usa.org

    His family broke down the door to find him unconscious on the floor. None of their lives were ever the same again. Christopher was diagnosed with epilepsy.A Smell of Burning tells the remarkable story of this strange and misunderstood disorder. How certain people, at a particular moment in their life, start to suffer seizures, often preceded by an aura, of which a smell of burning is one of the most common.For many years epilepsy was associated with mental illness or even possession by devils. People with epilepsy were forbidden to marry or have children. Many became victims of Nazi eugenics programmes. To this day many people with epilepsy – sixty million worldwide – still live in fear of exposure.Grant’s book traces the history of the condition and the pioneering doctors whose extraordinary breakthroughs finally helped gain an understanding of how the brain works. He tells the stories of famous people with epilepsy like Julius Caesar, Joan of Arc, Fyodor Dostoevsky and Vincent Van Gogh, and through the tragic tale of his brother, he considers the effect of epilepsy on his own life.

    Will take 25-35 days

    

    In this delightful and compelling exploration of our most neglected sense, veteran science reporter Bob Holmes shows us just how much we’re missing.Considering every angle of flavor from our neurobiology to the science and practice of modern food production, Holmes takes readers on a journey to uncover the broad range of factors that can affect our appreciation of a fine meal or an exceptional glass of wine. He peers over the shoulders of some of the most fascinating food professionals working today, from cutting-edge chefs to food engineers to mathematicians investigating the perfect combination of pizza toppings. He talks with flavor and olfactory scientists, who describe why two people can experience remarkably different sensations from the same morsel of food, and how something as seemingly unrelated as cultural heritage can actually impact our sense of smell.Along the way, even more surprising facts are revealed: that cake tastes sweetest on white plates; that wine experts’ eyes can fool their noses; and even that language can affect our sense of taste. Flavor expands our curiosity and understanding of one of our most intimate sensations, while ultimately revealing how we can all sharpen our senses and our enjoyment of the things we taste.Certain to fascinate everyone from gourmands and scientists to home cooks and their guests, Flavor will open your mind—and palette—to a vast, exciting sensory world.

    Then it spreads. Even though an MRI finds a “mass” on her brainstem, it takes two more years for Meredith O’Brien to learn what is causing that numbness. Months after her 65-year-old mother dies from a fast-moving cancer, weeks after her father is hospitalized and she experiences an unexpected job change, she learns she has multiple sclerosis.Suddenly, Meredith, a married mother of three teens, has to figure out how to move forward into a life she no longer recognizes. Reimagining her life as a writer and an educator, as a mother and a spouse, she has to adjust to the restrictions MS imposes on her. It is a life, altered.