It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    Alongside remarkable stories of people who have lost these abilities but adapted with courage, resilience and ingenuity, there is an added, personal element: one day in late 2005, Sacks became aware of a dazzling, flashing light in one part of his visual field; it was not the familiar migraine aura he had experienced since childhood, and just two days later a malignant tumor in one eye was diagnosed. In subsequent journal entries - some of which are included in The Mind's Eye - he chronicled the experience of living with cancer, recording both the effects of the tumor itself, and radiation therapy. In turning himself into a case history, Sacks has given us perhaps his most intimate, impressive and insightful (no pun intended) book yet.

    Drawing on an awesome breadth of research, he shows how, long ago, the narrowness of the newly bipedal human female's pelvis and the increasing size of infants' heads precipitated a crisis for the species. Natural selection allowed for the adaptation of the human female to this environmental stress by reconfiguring her hormonal cycles, entraining them with the periodicity of the moon. The results, however, did much more than ensure our existence; they imbued women with the concept of time, and gave them control over sex--a power that males sought to reclaim. And the possibility of achieving immortality through heirs drove men to construct patriarchal cultures that went on to dominate so much of human history.From the nature of courtship to the evolution of language, Shlain's brilliant and wide-ranging exploration stimulates new ways of thinking about very old matters."A masterpiece of ideas and a unique contribution to our understanding of gender and history, sexuality and evolution." -- Jean Houston[Note: includes Reader's Guide]

    Tackling subjects like addiction, fertility, feminism and sexual violence, and where these subjects intersect with legislation, these beautifully written essays are at once fascinating and funny, intimate and searingly honest. Honest, raw, brave and new, Notes to Self breaks new ground in the field of personal essays.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    Before our names, before we have likes and dislikes - before we, or anyone else, has any idea who we are. And two years ago, as Juno Dawson went to tell her mother she was (and actually, always had been) a woman, she started to realise just how wrong we've been getting it.Gender isn't just screwing over trans people, it's messing with everyone. From little girls who think they can't be doctors to teenagers who come to expect street harassment. From exclusionist feminists to 'alt-right' young men. From men who can't cry to the women who think they shouldn't. As her body gets in line with her mind, Juno tells not only her own story, but the story of everyone who is shaped by society's expectations of gender - and what we can do about it. Featuring insights from well-known gender, feminist and trans activists including Rebecca Root, Laura Bates, Gemma Cairney, Anthony Anaxagorou, Hannah Witton, Alaska Thunderfuck and many more, The Gender Games is a frank, witty and powerful manifesto for a world in which everyone can truly be themselves.

    Why? Because without the power to make decisions about our own bodies, there is no democracy." —Gloria Steinem “Dr. Diana Greene Foster brings what is too often missing from the public debate around abortion: science, data, and the real-life experiences of people from diverse backgrounds…This should be required reading for every judge, member of Congress, and candidate for office—as well as anyone who hopes to better understand this complex and important issue.” —Cecile Richards, cofounder of Supermajority, former president of Planned Parenthood, and author of Make Trouble A groundbreaking and illuminating look at the state of abortion access in America and the first long-term study of the consequences—emotional, physical, financial, professional, personal, and psychological—of receiving versus being denied an abortion on women’s lives.What happens when a woman seeking an abortion is turned away? Diana Greene Foster, PhD, decided to find out. With a team of scientists—psychologists, epidemiologists, demographers, nursing scholars, and public health researchers—she set out to discover the effect of receiving versus being denied an abortion on women’s lives. Over the course of a ten-year investigation that began in 2007, she and her team followed a thousand women from more than twenty states, some of whom received their abortions, some of whom were turned away. Now, for the first time, the results of this landmark study—the largest of its kind to examine women’s experiences with abortion and unwanted pregnancy in the United States—have been gathered together in one place. Here Foster presents the emotional, physical, and socioeconomic outcomes for women who received their abortion and those who were denied. She analyzes the impact on their mental and physical health, their careers, their romantic lives, their professional aspirations, and even their existing and future children—and finds that women who received an abortion were almost always better off than women who were denied one. Interwoven with these findings are ten riveting first-person narratives by women who share their candid stories. As the debate about abortion rights intensifies, The Turnaway Study offers an in-depth examination of the real-world consequences for women of being denied abortions and provides evidence to refute the claim that abortion harms women. With brilliant synthesis and startling statistics—that thousands of American women are unable to access abortions; that 99% of women who receive an abortion do not regret it five years later—The Turnaway Study is a necessary and revelatory look at the impact of abortion access on people’s lives.

    He was told—like his entire generation—that his problem was caused by a chemical imbalance in his brain. As an adult, trained in the social sciences, he began to investigate this question—and he learned that almost everything we have been told about depression and anxiety is wrong. Across the world, Hari discovered social scientists who were uncovering the real causes—and they are mostly not in our brains, but in the way we live today. Hari’s journey took him from the people living in the tunnels beneath Las Vegas, to an Amish community in Indiana, to an uprising in Berlin—all showing in vivid and dramatic detail these new insights. They lead to solutions radically different from the ones we have been offered up until now.Just as Chasing the Scream transformed the global debate about addiction, with over twenty million views for his TED talk and the animation based on it, Lost Connections will lead us to a very different debate about depression and anxiety—one that shows how, together, we can end this epidemic.

    Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?In a swift and breathtaking narrative, Cahalan tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that nearly didn’t happen.

    His book explains carefully and convincingly why--and how--men can become part of the solution, and work with women to build a world in which everyone is safer." --Michael Kimmel, author of Manhood in America, spokesperson, National Organization for Men Against Sexism (NOMAS)"If only men would read Katz's book, it could serve as a potent form of male consciousness-raising."--Publishers Weekly"This book leaves no man behind when it comes to taking violence against women personally....After reading this book you can see how important it is to be a stand-up guy and not a standy-by guy, no matter what race or culture you come from."--Alfred L. McMichael, 14th Sergeant Major of the Marine Corps and now serving as the Sergeant Major of NATO"A candid look at the cultural factors that lend themselves to tolerance of abuse and violence against women."--Booklist"These pages will empower both men and women to end the scourge of male violence and abuse. Katz knows how to cut to the core of the issues, demonstrating undeniably that stopping the degradation of women should be every man's priority."--Lundy Bancroft, author of Why Does He Do That?: Inside the Minds of Angry and Controlling Men

    This is the book that brought gender differences in ways of speaking to the forefront of public awareness. With a rare combination of scientific insight and delightful, humorous writing, Tannen shows why women and men can walk away from the same conversation with completely different impressions of what was said.Studded with lively and entertaining examples of real conversations, this book gives you the tools to understand what went wrong -- and to find a common language in which to strengthen relationships at work and at home. A classic in the field of interpersonal relations, this book will change forever the way you approach conversations.

    Vulnerable yet tough, she eventually ended up a victim of commercial sexual exploitation. It took time and incredible resilience, but finally, with the help of a local church community, she broke free of her pimp and her past. Three years later, Lloyd arrived in the United States to work with adult women in the sex industry and soon founded her own nonprofit— GEMS, Girls Educational and Mentoring Services—to meet the needs of other girls with her history. She also earned her GED and won full scholarships to college and a graduate program. Today Lloyd is executive director of GEMS in New York City and has turned it into one of the nation's most groundbreaking nonprofit organizations. In Girls Like Us, Lloyd reveals the dark, secretive world of her past in stunning cinematic detail. And, with great humanity, she lovingly shares the stories of the girls whose lives she has helped—; small victories that have healed her wounds and made her whole. Revelatory, authentic, and brave, Girls Like Us is an unforgettable memoir.

    Shameful to talk about and often misunderstood, loneliness is everywhere, from the most major of metropolises to the smallest of towns.In Seek You, Kristen Radtke's wide-ranging exploration of our inner lives and public selves, Radtke digs into the ways in which we attempt to feel closer to one another, and the distance that remains. Through the lenses of gender and violence, technology and art, Radtke ushers us through a history of loneliness and longing, and shares what feels impossible to share.Ranging from the invention of the laugh-track to the rise of Instagram, the bootstrap-pulling cowboy to the brutal experiments of Harry Harlow, Radtke investigates why we engage with each other, and what we risk when we turn away. With her distinctive, emotionally charged drawings and deeply empathetic prose, Kristen Radtke masterfully shines a light on some of our most vulnerable and sublime moments, and asks how we might keep the spaces between us from splitting entirely.

    But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.