We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Charles Bernstein here proves them alive and well in poems elegiac, defiant, and resilient to the point of approaching song. Heir to the democratic and poetic sensibilities of Walt Whitman and Allen Ginsberg, Bernstein has always crafted verse that responds to its historical moment, but no previous collection of his poems so specifically addresses the events of its time as Girly Man, whichfeatures works written on the evening of September 11, 2001, and in response to the war in Iraq. Here, Bernstein speaks out, combining self-deprecating humor with incisive philosophical and political thinking. Composed of works of very different forms and moods—etchings from moments of acute crisis, comic excursions, formal excavations, confrontations with the cultural illogics of contemporary political consciousness—the poems work as an ensemble, each part contributing something necessary to an unrealizable and unrepresentable whole. Indeed, representation—and related claims to truth and moral certainty—is an active concern throughout the book. The poems of Girly Man may be oblique, satiric, or elusive, but their sense is emphatic. Indeed, Bernstein’s poetry performsits ideas so that they can be experienced as well as understood. A passionate defense of contingency, resistance, and multiplicity, Girly Man is a provocative and aesthetically challenging collection of radical verse from one of America’s most controversial poets.

    In other words, by all of us."--Dr. Bernie Siegel, author of Love, Medicine and MiraclesRule One for the neurologist in residence: "You ain't never the same when the air hits your brain." In this fascinating book, Dr. Frank Vertosick brings that fact to life through intimate portraits of patients and unsparing yet gripping descriptions of brain surgery.With insight, humor, and poignancy, Dr. Vertosick chronicles his remarkable evolution from naive young intern to world-class neurosurgeon, where he faced, among other challenges, a six week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22 caliber bullet lodged in his skull. In candid detail, WHEN THE AIR HITS YOUR BRAIN illuminates both the mysteries of the mind and the realities of the operating room."Riveting."--Publishers Weekly

    A simple muscle test can tell you what stimuli can strengthen or weaken you--how your body responds to stress, posture, specific foods, emotions, and your entire social and physical environments. Based on the role of the thymus gland in regulating body energy, this laboratory-tested method can guide you into a more vital, healthier way of life. Begin benefiting now from Dr. John Diamond's unique, personal synthesis of developments in psychiatry, preventive medicine, kinesiology, nutrition, and music therapy.

     Do surgeons talk about their sex lives while cutting a heart open? How do surgeons respond to death? How do they react when asked to save the life of an abuser, criminal, or addict? Since its debut, the ABC medical drama Grey's Anatomy has asked such questions. With an emphasis on the personal lives of the surgical interns, residents, and attending physicians, the show has generated interest in how these professionals survive this rigorous educational program. How much of its drama is entertainment, and how much is accurate? Here, a medical journalist provides answers. He examines a group of new surgical residents in the Pacific Northwest as they tackle long hours, fascinating procedures, and emotional ups and downs that comprise the life of a student of surgery.

    An elderly Chinese immigrant sacrifices his demented wife's well-being to his son's authority. A busy Latina physician's eldest daughter's need for more attention has disastrous consequences. A young veteran's injuries become a metaphor for the rest of his life. A gay doctor learns very different lessons about family from his life and his work, and a psychiatrist who advocates for the underserved may herself be crazy. Together, these honest and compassionate stories introduce a striking new literary voice and provide a view of what it means to be a doctor and a patient unlike anything we've read before. In the tradition of Oliver Sacks and Abraham Verghese, Aronson's writing is based on personal experience and addresses topics of current social relevance. Masterfully told, A History of the Present Illness explores the role of stories in medicine and creates a world pulsating with life, speaking truths about what makes us human.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    Caroline's revelation will change the way you think. This book is the owner's manual for how our brains work."--Matthew and Laurie Crouch, Trinity Broadcasting Network"Caroline Leaf has given us a real jewel, translating modern brain science into language accessible to everyone."--David I. Levy, MD, neurosurgeon, author of Gray Matter"[Caroline] explains how our choices work scientifically, but in a practical way that makes something that is really hard to do much easier and more tangible."--Christine Caine, founder of the A21 Campaign; director of Equip and Empower Ministries; author of Undaunted"We encourage you to act on the wisdom found in Switch On Your Brain and begin the incredible journey of thinking God's way."--Robert and Debbie Morris, pastors of Gateway Church; authors of The Blessed Life, The Blessed Marriage, and The Blessed Woman"Dr. Leaf's teaching is not only life changing but life saving as it makes the renewing of the mind so real. I am so very grateful for the wisdom contained within these pages."--Darlene Zschech, singer-songwriter; author of The Art of Mentoring"Each of us is full of untapped potential when it comes to our ability to think and process our way through life. I pray that Caroline's years of research and passion in this realm of unfolding science will be a blessing to you."--Bobbie Houston, senior pastor, Hillsong Church

    It is a symptom.Recent years have seen a shocking increase in antidepressant use the world over, with 1 in 4 women starting their day with medication. These drugs have steadily become the panacea for everything from grief, irritability, panic attacks, to insomnia, PMS, and stress.  But the truth is, what women really need can’t be found at a pharmacy.According to Dr. Kelly Brogan, antidepressants not only overpromise and underdeliver, but their use may permanently disable the body’s self-healing potential. We need a new paradigm: The best way to heal the mind is to heal the whole body.In this groundbreaking, science-based and holistic approach, Dr. Brogan shatters the mythology conventional medicine has built around the causes and treatment of depression. Based on her expert interpretation of published medical findings, combined with years of experience from her clinical practice, Dr. Brogan illuminates the true cause of depression: it is not simply a chemical imbalance, but a lifestyle crisis that demands a reset. It is a signal that the interconnected systems in the body are out of balance – from blood sugar, to gut health, to thyroid function– and inflammation is at the root.A Mind of Your Own offers an achievable, step-by-step 30-day action plan—including powerful dietary interventions, targeted nutrient support, detoxification, sleep, and stress reframing techniques—women can use to heal their bodies, alleviate inflammation, and feel like themselves again without a single prescription.Bold, brave, and revolutionary, A Mind of Your Own takes readers on a journey of self-empowerment for radical transformation that goes far beyond symptom relief.

    The set includes thirty-one 30-minute MCAT practice exams with answers and explanations and more than 1,600 MCAT questions.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    In fact, one in eight Americans--a shocking 43 million people--do not have any health care insurance at all. One Nation, Uninsured offers a vividly written history of America's failed efforts to address the health care needs of its citizens. Covering the entire twentieth century, Jill Quadagno shows how each attempt to enact national health insurance was met with fierce attacks by powerful stakeholders, who mobilized their considerable resources to keep the financing of health care out of the government's hands. Quadagno describes how at first physicians led the anti-reform coalition, fearful that government entry would mean government control of the lucrative private health care market. Doctors lobbied legislators, influenced elections by giving large campaign contributions to sympathetic candidates, and organized grassroots protests, conspiring with other like-minded groups to defeat reform efforts. As the success of Medicare and Medicaid in the mid-century led physicians and the AMA to start scaling back their attacks, the insurance industry began assuming a leading role against reform that continues to this day. One Nation, Uninsured offers a sweeping history of the battles over health care. It is an invaluable read for anyone who has a stake in the future of America's health care system.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Otis Brawley is the chief medical and scientific officer of The American Cancer Society, an oncologist with a dazzling clinical, research, and policy career. How We Do Harm pulls back the curtain on how medicine is really practiced in America. Brawley tells of doctors who select treatment based on payment they will receive, rather than on demonstrated scientific results; hospitals and pharmaceutical companies that seek out patients to treat even if they are not actually ill (but as long as their insurance will pay); a public primed to swallow the latest pill, no matter the cost; and rising healthcare costs for unnecessary—and often unproven—treatments that we all pay for. Brawley calls for rational healthcare, healthcare drawn from results-based, scientifically justifiable treatments, and not just the peddling of hot new drugs.Brawley's personal history – from a childhood in the gang-ridden streets of black Detroit, to the green hallways of Grady Memorial Hospital, the largest public hospital in the U.S., to the boardrooms of The American Cancer Society—results in a passionate view of medicine and the politics of illness in America - and a deep understanding of healthcare today. How We Do Harm is his well-reasoned manifesto for change.

    Whether you work in emergency medicine, or just want to be prepared, this book will be your essential guide.Following the latest clinical guidelines and evidence, written and reviewed by experts, this handbook will ensure you are up-to-date and have the confidence to deal with all emergency presentations, practices, and procedures. Following the latest developments in the field, such as infection control, DNR orders, advanced directives and learning disability. The book also includes new sections specifically outlining patient advice and information, as well as new and revised vital information on paediatrics and psychiatry. For all junior doctors, specialist nurses, paramedics, clinical students, GPs and other allied health professionals, this rapid-reference handbook will become a vital companion for both study and practice.