In this Very Short Introduction, eminent biologist and popular science writer Dorothy Crawford offers a fascinating portrait of these infinitesimally small but often highly dangerous creatures. Crawford first relates how viruses were discovered and she unravels the intricate structures of tiny parasites that are by far the most abundant life forms on the planet. Analyzing the threat of viral infections, Crawford recounts stories of renowned killer viruses such as Ebola and rabies as well as the less known bat-borne Nipah and Hendra viruses. She identifies wild animals as the source of the most recent pandemics, detailing the reasons behind the present increase in potentially fatal infections, and evaluating the evidence that suggests that long term viruses can eventually lead to cancer. Finally, Crawford looks to the future to ask whether we can ever live in harmony with viruses, and considers ways to prevent the emergence of new and devastating viruses.

    In fact, it’s amazing that it doesn’t get us sooner: we fight off millions of disease-causing germs every day.So how come we’re not dead yet? In this lively and accessible book, Idan Ben-Barak tells us why. He explores the immune system and what keeps it running, how germs are destroyed, and why we develop immunities to certain disease-causing agents. He also examines the role of antibiotics and vaccines, and looks at what the future holds for our collective chances of not being dead.This is entertaining and thoughtful science writing to inspire the student interested in a career in medicine or immunology, or to inform the reader who just wants to understand more about their body while having a laugh along the way.

    Beginning in the 1950s when doctors still paid house calls but regularly withheld the truth from their patients, Amy Gutmann and Jonathan D. Moreno explore an unprecedented revolution in health care and explain the problem with America’s wanting everything that medical science has to offer without debating its merits and its limits. The result: Americans today pay far more for health care while having among the lowest life expectancies and highest infant mortality of any affluent nation.Gutmann and Moreno—“incisive, influential, and pragmatic thinkers” (Arthur Caplan)—demonstrate that the stakes have never been higher for prolonging and improving life. From health care reform and death-with-dignity to child vaccinations and gene editing, they explain how bioethics came to dominate the national spotlight, leading and responding to a revolution in doctor-patient relations, a burgeoning world of organ transplants, and new reproductive technologies that benefit millions but create a host of legal and ethical challenges.With striking examples, the authors show how breakthroughs in cancer research, infectious disease, and drug development provide Americans with exciting new alternatives, yet often painful choices. They address head-on the most fundamental challenges in American health care: Why do we pay so much for health care while still lacking universal coverage? How can medical studies adequately protect individuals who volunteer for them? What’s fair when it comes to allocating organs for transplants in truly life-and-death situations?A lucid and provocative blend of history and public policy, this urgent work exposes the American paradox of wanting to have it all without paying the price.

    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

    You will learn how in this timely, urgent, and compassionate work by a world-renowned critical care doctor.Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive. You will experience the world of critical care through the eyes of a physician who drastically changed his clinical practice to offer person-centered health care, and through cutting-edge research convinced others to do the same. For decades, ICU survivors left the hospital with disabling symptoms including newly acquired dementia, depression, PTSD, and nerve damage, all now recognized as Post Intensive Care Syndrome, or PICS. Dr. Ely’s groundbreaking investigations advanced the understanding of PICS and introduced crucial changes that reshaped intensive care: minimizing sedation, maximizing mobility, listening to the family, and providing supportive aftercare. Dr. Ely shows that there are ways to bring humanity into the ICU and that “technology plus touch” is the future of health care and is a proven path toward returning ICU patients to the lives they had before their hospital stay. An essential resource for anyone who will be affected by illness—which is all of us—Ely’s “personal, passionate return to the ethical heart of the Hippocratic oath…[offers] meaningful, thought-provoking insight into the world of critical care” (Kirkus Reviews).

    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s.One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline.In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

    Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.

    The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    Our stories are marbled into their marrow.Drawing upon her years of research and a wealth of remarkable experience, the world-renowned forensic anthropologist Professor Dame Sue Black takes us on a journey of revelation. From skull to feet, via the face, spine, chest, arms, hands, pelvis and legs, she shows that each part of us has a tale to tell. What we eat, where we go, everything we do leaves a trace, a message that waits patiently for months, years, sometimes centuries, until a forensic anthropologist is called upon to decipher it.Some of this information is easily understood, some holds its secrets tight and needs scientific cajoling to be released. But by carefully piecing together the evidence, the facts of a life can be rebuilt. Limb by limb, case by case – some criminal, some historical, some unaccountably bizarre – Sue Black reconstructs with intimate sensitivity and compassion the hidden stories in what we leave behind.

    You’ve had a martini or three, and you mingle through the crowd, wondering how long you need to stay before going out for pizza. Suddenly you’re introduced to someone new, Dr. Nice Tomeetya. You forget the pizza. Now is the perfect time to bring up all those strange questions you’d like to ask during an office visit with your own doctor but haven’t had the guts (or more likely the time) to do so. You’re filled with liquid courage . . . now is your chance! If you’ve ever wanted to ask a doctor . . .•How do people in wheelchairs have sex?•Why do I get a killer headache when I suck down my milkshake too fast?•Can I lose my contact lens inside my head forever?•Why does asparagus make my pee smell?•Why do old people grow hair on their ears?•Is the old adage “beer before liquor, never sicker, liquor before beer . . .” really true? . . . then Why Do Men Have Nipples? is the book for you.Compiled by Billy Goldberg, an emergency medicine physician, and Mark Leyner, bestselling author and well-known satirist, Why Do Men Have Nipples? offers real factual and really funny answers to some of the big questions about the oddities of our bodies.