. . Sanghavi is a vivid and effortless teller of human tales and quite evidently a special doctor, too." —Atul Gawande, author of ComplicationsIn this compelling book, Dr. Darshak Sanghavi takes the reader on a dramatic tour of a child's eight vital organs, beginning with the lungs and proceeding through the heart, blood, bones, brain, skin, gonads, and gut.Along the way, we meet children and families in extraordinary circumstances—a premature baby named Adam Flax who was born with undeveloped lungs, a teenage boy with a positive pregnancy test, and a young girl who keeps losing weight despite her voracious appetite. In a deeply personal narrative, Sanghavi provides a richly detailed—and humanized—portrait of how the pediatric body functions in both sickness and health.

    The key to achieving HYPERGROWTH is being customer-driven. So if you’re ready to start putting your customers first, keep reading... What You’ll Learn: A New Approach to Product Management and Developing SaaS Products People Love Today, there’s no excuse for not communicating with customers on a daily basis. Messaging has exploded, new generations are focused on 1:1 communication by default, and artificial intelligence is finally coming so we can deliver 1:1 at scale. So why would you build a product, or a company, without leaning into the advantages of that ecosystem? In his new book, HYPERGROWTH, serial entrepreneur and Drift co-founder/CEO David Cancel shares a modern approach for building products and structuring teams that makes customer communication a central priority. The book tells the story of how Cancel’s customer-driven approach started out as a test with a product team (Performable), transformed an entire organization (HubSpot), and sparked a new movement (Drift). What’s Inside: Practical Advice and Frameworks for Becoming Customer-Driven and Growing Your Business Responsive Development (RD): a new approach to building products that adds the customer back into the equation The Burndown Framework: a framework for implementing Responsive Development that’s faster and more flexible than Agile. The Three-Person Team: the customer-driven way to structure engineering teams. Each team consists of a tech lead who manages two other engineers. Getting Rid of Roadmaps: through building a culture of transparency and accountability and working closely with internal customers, you can release product updates more rapidly and iteratively. The Spotlight Framework: a framework for helping you focus on the right parts of customer feedback so you can take the appropriate next steps. The framework breaks feedback down into three main categories: user experience issues, product marketing issues, and positioning issues. Who This Book Is For: Entrepreneurs, Startup Founders, Product Managers, Product Teams, Marketing Teams … Entire Companies! Every part of your business can benefit from being customer-driven. With the rise of SaaS and the on-demand economy, customer expectations have changed. Customers expect their voices to be heard. They find value in being part of a community, and being part of that journey of creating the product. So stop running your business like we’re still living in the 2000s. It’s time to take a customer-driven approach. Here’s what people are saying about the book: “David Cancel is one of the best when it comes to building products that customers love. And now he’s sharing his wisdom and writing the book explaining how he does it. This is a must read for any entrepreneur or business owner.” -MARK ROBERGE Senior Lecturer, Harvard Business School, Former SVP of Sale and Services at HubSpot ”When it comes to building business software, there’s no one better than David Cancel, and I saw fi

    Now in its sixth edition, this classic text continues its long-standing tradition of offering unparalleled guidance in the development of pharmaceutical care plans. The book provides a unique process of thinking about pharmacotherapy the process which uses evidence-based approaches to the drug treatment of diseases. Features: *FREE Online Resource Center for professors and students - study materials, web chapters, questions and answers, and updates *NEW Key Concepts begin each chapter *Excellent use of algorithms, tables, and charts - provides clear recommendations *"Clinical Controversies" in the treatment sections of disease-oriented chapters

    For many, it is as if they are traveling to someplace entirely new and they must go there alone, with only faded directions back to their old lives. Often, even their loved ones can only guess at what they must be experiencing.The Lonely Patient is a clear-eyed and deeply affecting examination of the inner life of those grappling with illness. It looks into the chasm between the well and the sick by exploring and giving voice to the often unarticulated aspects of illness, offering people with illness—and their family and friends—a frank and intelligent discussion of how to negotiate the psychological and emotional aspects of what they are going through.Michael Stein, M.D., a professor of medicine at Brown University Medical School as well as an acclaimed novelist, uses the stories of a number of patients, including that of his beloved, terminally ill brother-in-law, Richard, to consider the personal narrative of sickness. What sets Stein's book apart is his intimate scrutiny of the uniqueness of each patient's experience, which he breaks into four parts—betrayal, terror, loss, and loneliness—and renders each in such a way that he opens a dialogue about our expectations of health and, after its shocking disappearance, of illness.Beautifully written and keenly insightful, The Lonely Patient is a valuable book for patients and their caregivers—as well as a probing inquiry into a universal experience.

      You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated—and gives you too many forms to fill out. But the central problem is that too much medical care has too little value. Dr. H. Gilbert Welch is worried about too much medical care. It’s not to deny that some people get too little medical care, rather that the conventional concern about “too little” needs to be balanced with a concern about “too much”: too many people being made to worry about diseases they don’t have—and are at only average risk to get; too many people being tested and exposed to the harmful effects of the testing process; too many people being subjected to treatments they don’t need—or can’t benefit from. The American public has been sold the idea that seeking medical care is one of the most important steps to maintain wellness. Surprisingly, medical care is not, in fact, well correlated with good health. So more medicine does not equal more health; in reality the opposite may be true. The general public harbors assumptions about medical care that encourage overuse, assumptions like it’s always better to fix the problem, sooner (or newer) is always better, or it never hurts to get more information. Less Medicine, More Health pushes against established wisdom and suggests that medical care can be too aggressive. Drawing on his twenty-five years of medical practice and research, Dr. Welch notes that while economics and lawyers contribute to the excesses of American medicine, the problem is essentially created when the general public clings to these powerful assumptions about the value of tests and treatments—a number of which are just plain wrong. By telling fascinating (and occasionally amusing) stories backed by reliable data, Dr. Welch challenges patients and the health-care establishment to rethink some very fundamental practices. His provocative prescriptions hold the potential to save money and, more important, improve health outcomes for us all.

    Maybe you’re stuck in a boring industry. Maybe your boss likes to slam doors. The truth is that many smart, motivated people would quit in a heartbeat if they weren’t afraid of the financial risks…and, well, the unknown. Whether you want to upgrade your 9-5 or start your own company, Robbie Abed presents a foolproof strategy to find a better job—without stressing, worrying your family, or losing money. You’re talented. Talent is in high demand. You just have to know where to look. In this accessible handbook, full of anecdotes, stories, and tips, you’ll learn how to reconnect with your interests, sharpen your talents, build a network, experiment with ideas for next steps, elicit job offers, and negotiate for higher salaries than your last. Oh, and how to quit your job with aplomb (goodbye email template included). You’ve been miserable for long enough. Look at it this way: hating your job might be the best thing that could’ve happened to you. It’s a kick in the pants to learn survival skills for the coming jobpocalypse. As our machines get smarter, robots, cognitive machines, and the simple software on your computer will render old jobs obsolete. In other words, there is no such thing as job security. The goal of this book is twofold: to help you get out before the music stops, and to teach you skills to find a job you love. Not just once, but anytime, anywhere, in any economic climate, with almost any salary goal. You didn’t hear that wrong.

    If we’re not climbing the corporate ladder, building our side hustle, preparing home-cooked meals, tucking the kids in at night, meditating daily, and scheduling playdates, date nights, and girls’ nights every week, we feel like we’re not living our best lives. Yet traditional productivity books—written by men—barely touch the tangle of cultural pressures that women feel when facing down a to-do list. Finally, in the first productivity book by a woman in a decade, Erin Falconer will show you how to do less—a lot less. In fact, How to Get Sh*t Done will teach you how to zero in on the three areas of your life where you want to excel, and then it will show you how to off-load, outsource, or just stop giving a damn about the rest. As the founder of two technology start-ups and one of Refinery29’s Top 10 Women Changing the Digital Landscape for Good, Erin has seen what happens when women chase an outdated, patriarchal model of productivity, and in How to Get Sh*t Done she shows how even the most perfectionistic among us can tap into our inner free spirit and learn to feel like badasses, rather than drudges. Packed with real-life advice, honest stories from Erin’s successful career, and dozens of actionable resources, How to Get Sh*t Done will forever reframe productivity so that you can stop doing everything for everyone and start doing what matters to you.

    Kennedy delivered an historic speech on mental illness and retardation. He described sweeping new programs to replace "the shabby treatment of the many millions of the mentally disabled in custodial institutions" with treatment in community mental health centers. This movement, later referred to as "deinstitutionalization," continues to impact mental health care. Though he never publicly acknowledged it, the program was a tribute to Kennedy's sister Rosemary, who was born mildly retarded and developed a schizophrenia-like illness. Terrified she'd become pregnant, Joseph Kennedy arranged for his daughter to receive a lobotomy, which was a disaster and left her severely retarded. Fifty years after Kennedy's speech, E. Fuller Torrey's book provides an inside perspective on the birth of the federal mental health program. On staff at the National Institute of Mental Health when the program was being developed and implemented, Torrey draws on his own first-hand account of the creation and launch of the program, extensive research, one-on-one interviews with people involved, and recently unearthed audiotapes of interviews with major figures involved in the legislation. As such, this book provides historical material previously unavailable to the public. Torrey examines the Kennedys' involvement in the policy, the role of major players, the responsibility of the state versus the federal government in caring for the mentally ill, the political maneuverings required to pass the legislation, and how closing institutions resulted not in better care - as was the aim - but in underfunded programs, neglect, and higher rates of community violence. Many now wonder why public mental illness services are so ineffective. At least one-third of the homeless are seriously mentally ill, jails and prisons are grossly overcrowded, largely because the seriously mentally ill constitute 20 percent of prisoners, and public facilities are overrun by untreated individuals. As Torrey argues, it is imperative to understand how we got here in order to move forward towards providing better care for the most vulnerable.

    You cannot afford to be apolitical at work if you have any aspirations for advancement. The only way to avoid politics is to avoid people—by finding an out-of-the-way corner where you can do your job. Of course, it’s the same job you’ll likely be doing for the rest of your career.In any job, when you reach a certain level of technical competence, politics is what makes all the difference with regard to success. At that point, it is indeed all politics. Everyday brilliant people take a backseat to their politically adept colleagues by failing to win crucial support for their ideas. Sometimes politics involves going around or bending rules, but more typically it’s about positioning your ideas in a favorable light, and knowing what to say, and how and when to say it.…Keep in mind that people benefit from perpetuating the image of politics as something you either know or you don’t. Ignore them. Political acumen is largely learned from observation. And then it’s a matter of practice, practice, practice. When a journalist suggested that golfing great Gary Player was very lucky, he replied: “It’s funny, but the more I practice, the luckier I get.” The same is true of politics.An indispensable guide to mastering the ins and outs of office politics—the single most important factor in getting ahead in your careerAs management professor and consultant Kathleen Reardon explains in her new book, It's All Politics, talent and hard work alone will not get you to the top. What separates the winners from the losers in corporate life is politics.As Reardon explains, the most talented and accomplished employees often take a backseat to their politically adept coworkers, losing ground in the race to get ahead—sometimes even losing their jobs. Why? Because they’ve failed to manage the important relationships with the people who can best reward their creativity and intelligence. To determine whether you need a crash course in Office Politics 101, ask yourself the following questions:Do I get credit for my ideas?Do I know how to deal with a difficult colleague?Do I get the plum assignments?Do I have a mentor?Do I say no gracefully and pick my battles wisely?Am I in the loop?Reardon has interviewed hundreds of employees, from successful veterans to aspiring hopefuls, examining why some people who work hard and effectively at their jobs fall behind, while those who are adept at “reading the office tea leaves” forge ahead. Being politically savvy doesn’t mean being unethical or devious. At heart, it’s about listening to and relating to others, and making choices that advance everyone’s goals. Like it or not, when it comes to work, it’s all politics. And politics is all about knowing what to say, when to say it, and who to say it to.

    They will enable you to sculpt your body while improving your flexibility and sense of well-being. The results are visible after only a few sessions.

    Learn about the components of a BI architecture, how to choose the appropriate tools and technologies, and how to roll out a BI strategy throughout the organisation.

    Why are so many RNs dropping out of health care's largest profession? How will the lack of skilled, experienced caregivers affect patients? These are some of the questions addressed by Suzanne Gordon's definitive account of the world's nursing crisis. In Nursing against the Odds, one of North America's leading health care journalists draws on in-depth interviews, research studies, and extensive firsthand reporting to help readers better understand the myriad causes of and possible solutions to the current crisis.Gordon examines how health care cost cutting and hospital restructuring undermine the working conditions necessary for quality care. She shows how the historically troubled workplace relationships between RNs and physicians become even more dysfunctional in modern hospitals. In Gordon's view, the public image of nurses continues to suffer from negative media stereotyping in medical shows on television and from shoddy press coverage of the important role RNs play in the delivery of health care.Gordon also identifies the class and status divisions within the profession that hinder a much-needed defense of bedside nursing. She explains why some policy panaceas--hiring more temporary workers, importing RNs from less-developed countries--fail to address the forces that drive nurses out of their workplaces. To promote better care, Gordon calls for a broad agenda that includes safer staffing, improved scheduling, and other policy changes that would give nurses a greater voice at work. She explores how doctors and nurses can collaborate more effectively and what medical and nursing education must do to foster such cooperation. Finally, Gordon outlines ways in which RNs can successfully take their case to the public while campaigning for health care system reform that actually funds necessary nursing care.

    This concise introduction shows you how to perform statistical analysis computationally, rather than mathematically, with programs written in Python.You'll work with a case study throughout the book to help you learn the entire data analysis process—from collecting data and generating statistics to identifying patterns and testing hypotheses. Along the way, you'll become familiar with distributions, the rules of probability, visualization, and many other tools and concepts.Develop your understanding of probability and statistics by writing and testing codeRun experiments to test statistical behavior, such as generating samples from several distributionsUse simulations to understand concepts that are hard to grasp mathematicallyLearn topics not usually covered in an introductory course, such as Bayesian estimationImport data from almost any source using Python, rather than be limited to data that has been cleaned and formatted for statistics toolsUse statistical inference to answer questions about real-world data

    Gigabytes, exabytes (that’s one quintillion bytes) of data are sitting on servers across the world. So how can we start to access this explosion of information, this “big data,” and what can it tell us?   Erez Aiden and Jean-Baptiste Michel are two young scientists at Harvard who started to ask those questions. They teamed up with Google to create the Ngram Viewer, a Web-based tool that can chart words throughout the massive Google Books archive, sifting through billions of words to find fascinating cultural trends. On the day that the Ngram Viewer debuted in 2010, more than one million queries were run through it.   On the front lines of Big Data, Aiden and Michel realized that this big dataset—the Google Books archive that contains remarkable information on the human experience—had huge implications for looking at our shared human history. The tool they developed to delve into the data has enabled researchers to track how our language has evolved over time, how art has been censored, how fame can grow and fade, how nations trend toward war. How we remember and how we forget. And ultimately, how Big Data is changing the game for the sciences, humanities, politics, business, and our culture.

    Difficult issues need to be figured out, such as scalability, consistency, reliability, efficiency, and maintainability. In addition, we have an overwhelming variety of tools, including relational databases, NoSQL datastores, stream or batch processors, and message brokers. What are the right choices for your application? How do you make sense of all these buzzwords?In this practical and comprehensive guide, author Martin Kleppmann helps you navigate this diverse landscape by examining the pros and cons of various technologies for processing and storing data. Software keeps changing, but the fundamental principles remain the same. With this book, software engineers and architects will learn how to apply those ideas in practice, and how to make full use of data in modern applications. Peer under the hood of the systems you already use, and learn how to use and operate them more effectively Make informed decisions by identifying the strengths and weaknesses of different tools Navigate the trade-offs around consistency, scalability, fault tolerance, and complexity Understand the distributed systems research upon which modern databases are built Peek behind the scenes of major online services, and learn from their architectures