Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    Mike Israetel, PhD in Sport Physiology and professor of Exercise Science at the University of Central Missouri, handles the nutrition of top athletes in strength and physique sports and created The Renaissance Diet to help you perform better and get the body that you want.Along with Dr. Mike’s expertise, Dr. Jennifer Case and Dr. James Hoffmann lend their expertise to create a comprehensive guide on how much to eat, what to eat and when to eat it, to maximize your performance and have a physique to match your strength.The Renaissance Diet will help you…-Understand how many calories you need to eat to maximize performance and burn fat.-Correctly balance your macronutrient intake for your training and physique goals.-Time your meals to get the most out of your nutrition.-Select optimal foods to fuel performance.-Understand which supplements actually work and why.-Improve your health with proper micronutrient intake and hydration.-Periodize your diet for long term effectiveness.-Dispel common diet myths and fads-Improve your training with the included ‘Trinity Powerlifting Templates’-Understand your nutritional priorities from Dr. Mike's hour long video presentation from Juggernaut's Become Unstoppable Seminar 3With so much information and misinformation available now about nutrition, you need sources you can trust. The authors of The Renaissance Diet combine scientific expertise with practical knowledge.Dr. Israetel, Dr. Case and Dr. Hoffman not only have PhDs and are actively serving as professors and researchers, they are also high level competitors and coaches in powerlifting, bodybuilding, rugby, and combat sports. This combination of scientific knowledge and practical experience is the best in helping you achieve your goals.The Renaissance Diet: A Scientific Approach to Getting Leaner and Building Muscle is your ultimate guide to learning how to more effectively and efficiently fuel your body for improved performance and a better physique. Let these experts take the guesswork out of your nutrition and starting reaching your goals now.

    The implications of their discoveries form tomorrow's headlines, yet Angier writes about the scientists themselves and not merely theri successes. 4-page photo insert.

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    The most current information on the mechanisms, manifestations, and treatments of disease are clearly and concisely presented. Accessible writing, numerous illustrations in full-color, and complete and separate treatment of pediatric pathophysiology are the hallmarks of this popular and respected text. The new third edition features extensively revised and updated content and an enhanced art program.The book is divided into two parts. Part One presents the general principles of pathophysiology, including cell injury and repair; genetics; fluids and electrolytes, acids and bases; immunity, inflammation, and infection; stress; and cancer. Part Two is organized by body system, and for each system it covers normal anatomy and physiology, alterations of function in adults, and alterations of function in children.• Complete but concise coverage provides a thorough discussion of general pathophysiology and specific disease processes. • Outstanding full-color art program illustrates normal anatomy and physiology, disease processes, and clinical manifestations of disease. • Pediatric content is presented in 9 separate chapters to provide thorough coverage of how disease processes specifically affect children. • Health Alert boxes present brief discussions of new research, diagnostic studies, preventative care, treatments, or other developments related to health or specific diseases. • Quick Check questions appear at the end of major sections of text and are designed to promote critical thinking. Suggested answers to the questions are found on the CD companion included with the text. • Risk Factor boxes illustrate how certain risk factors are associated with specific diseases. • Did You Understand? chapter summaries provide students with a comprehensive review of the major concepts presented in each chapter. • Aging content is identified with a special icon within the adult chapters. • Algorithms are used throughout the text to illustrate normal and compensatory physiology and pathophysiology. • Key terms are boldface in text and listed with page numbers at the end of each chapter for easy reference and chapter review.• Approximately 250 new full-color drawings have been added. • An Introduction to Pathophysiology included in the front matter defines pathophysiology — and related terms such as etiology and epidemiology — and explains why it is important. • Extensive updates, based on the most current research, have been made throughout the book. • To reflect the latest developments, the Biology of Cancer chapter has been completely rewritten. • Several chapters, including Fluids and Electrolytes, Acids and Bases and Alterations of the Reproductive Systems have been extensively edited.

    Kelly A. Turner, founder of the Radical Remission Project, uncovers nine factors that can lead to a spontaneous remission from cancer—even after conventional medicine has failed.While getting her Ph.D. at the University of California, Berkley, Dr. Turner, a researcher, lecturer, and counselor in integrative oncology, was shocked to discover that no one was studying episodes of radical (or unexpected) remission—when people recover against all odds without the help of conventional medicine, or after conventional medicine has failed.  She was so fascinated by this kind of remission that she embarked on a ten month trip around the world, traveling to ten different countries to interview fifty holistic healers and twenty radical remission cancer survivors about their healing practices and techniques. Her research continued by interviewing over 100 Radical Remission survivors and studying over 1000 of these cases.  Her evidence presents nine common themes that she believes may help even terminal patients turn their lives around.

    This gloriously illustrated volume provides comprehensive college-level information about birds and their environments in a style accessible to nonscientists and teachers the world over.The "Handbook of Bird Biology" covers all major topics, from anatomy and physiology to ecology, behavior, and conservation biology. One full chapter addresses vocal communication and is accompanied by a CD of bird vocalizations. Produced by the Cornell Laboratory of Ornithology's world-renowned Macaulay Library of Natural Sounds, the CD illustrates key elements of bioacoustics.The book's text was written by 12 leading ornithologists and illustrated by respected photographers and acclaimed artist John Schmitt. It includes an extensive glossary and index, a list of the common and scientific names of all birds mentioned in the text, author profiles, suggested readings following each chapter, and a complete reference section.The "Handbook" serves as the backbone of the Lab's popular Home Study Course in Bird Biology, a self-paced course that can be taken from anywhere in the world, by anyone with a serious interest in birds who would like guidance from professional ornithologists. Comprehensive and readable guide covering all major topicsFree CD of bird vocalizations enclosedExtensive glossary and indexList of all common and scientific namesSuggested readingsComplete reference sectionCompanion to the Cornell Laboratory of Ornithology's popular Home Study Course in Bird Biology

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

    Despite decades of research and millions of dollars invested in uncovering the causes and developing treatments for this devastating illness, progress has been slow, with each new "blockbuster" drug proving to be as big a disappointment as the ones that went before it. Today, an Alzheimer's diagnosis is a death sentence.However, there may be ways to prevent, delay, and possibly even reverse the course of this crippling neurodegenerative disease. In The Alzheimer's Antidote, Certified Nutrition Specialist Amy Berger presents a multi-pronged nutrition and lifestyle intervention to combat Alzheimer's disease at its roots. Berger's research shows that Alzheimer's results from a fuel shortage in the brain: As neurons become unable to harness energy from glucose, they atrophy and die, leading to classic symptoms like memory loss and behavioral changes.This is a revolutionary approach--one that has been discussed in the scientific literature for years but has only recently been given credence in clinical settings, thanks to extremely promising studies wherein Alzheimer's patients have experienced complete reversals of the condition. Medical and scientific journals are full of research showing alternate ways to fuel the starving brain, but no one has been bringing this essential information to the people who need it most--until now.In a culture obsessed with miracle medications, the pharmaceutical route for tackling Alzheimer's has been a massive failure. Pills and potions don't address underlying causes, and regarding Alzheimer's, they typically fail to improve even the symptoms. As a metabolic problem, the only effective way to treat Alzheimer's may be a multifaceted approach that fundamentally reprograms energy generation in the brain. The good news is, the secret is as simple as switching to a low-carb, high-fat diet.The Alzheimer's Antidote shows us that cognitive decline is not inevitable, but if it does occur, we don't have to sit idly by and wait helplessly while it progresses and worsens. Amy Berger empowers loved ones and caregivers of Alzheimer's sufferers, and offers hope and light against this otherwise unnavigable labyrinth of darkness.

    Becoming Ageless presents a three-month, detailed diet and exercise plan to create a leaner, more muscular and happier you. Developed by business mogul and fitness buff Strauss Zelnick--founder of the private equity firm Zelnick Media Capital and president and CEO of Take-Two Interactive, the company behind blockbuster video games such as Grand Theft Auto and NBA2K-- the strategies contained in Becoming Ageless are the same tactics that allowed Zelnick to evolve from a skinny, out-of-shape business executive (a workaholic wunderkind who headed the film studio 20th Century Fox in his early 30s) to one of the world's fittest and most physically active executives who reached his best-ever shape in his late 50s! "If you believe my fitness buddies," Zelnick writes, "I have a body that's aging in reverse...And Becoming Ageless is filled with the amazing tips and unique principles you'd find if you trained with me."

    If you suffer from ailments your doctors can’t seem to diagnose or help—mysterious rashes, unpredictable digestive problems, debilitating headaches, mood and energy swings, constant tiredness—nerve compression is the likely cause. Over the years, Dr. Richard Jacoby has treated thousands of patients with peripheral neuropathy. Now, he shares his insights as well as the story of how he connected the dots to determine how sugar is the common denominator of many chronic diseases. In Sugar Crush, he offers a unique holistic approach to understanding the exacting toll sugar and carbs take on the body. Based on his clinical work, he breaks down his highly effective methods, showing how dietary changes reducing sugar and wheat, coinciding with an increase of good fats, can dramatically help regenerate nerves and rehabilitate their normal function.Sugar Crush includes a quiz to assess your nerve damage, practical dietary advice, and the latest thinking on ways to prevent and reverse neuropathy. If you have diabetes, this essential guide will help you understand the dangers and give you the tools you need to make a difference beyond your doctor’s prescriptions. If you have the metabolic syndrome or prediabetes, or are just concerned about your health, it will help you reverse and prevent nerve damage.

    The Tao of Healthy Eating illuminates the theory and practice of Chinese dietary therapy with emphasis on the concerns and attitudes of Westerners. Commonsense metaphors explain basic Chinese medical theories and their application in preventive and remedial dietary therapy. It features a clear description of the Chinese medical understanding of digestion and all the practical implications of this day-to-day diet. Issues of Western interest are discussed, such as raw versus cooked foods, high cholesterol, food allergies, and candidiasis. It includes the Chinese medical descriptions of 200 Western foods and similar information on vitamins, minerals, and amino acids.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

    You see the smokers, the overeaters, the bottle-feeders, and affirm your own health in the process. In these and countless other instances, the perception of your own health depends in part on your value judgments about others, and appealing to health allows for a set of moral assumptions to fly stealthily under the radar.Against Health argues that health is a concept, a norm, and a set of bodily practices whose ideological work is often rendered invisible by the assumption that it is a monolithic, universal good. And, that disparities in the incidence and prevalence of disease are closely linked to disparities in income and social support. To be clear, the book's stand against health is not a stand against the authenticity of people's attempts to ward off suffering. Against Health instead claims that individual strivings for health are, in some instances, rendered more difficult by the ways in which health is culturally configured and socially sustained.The book intervenes into current political debates about health in two ways. First, Against Health compellingly unpacks the divergent cultural meanings of health and explores the ideologies involved in its construction. Second, the authors present strategies for moving forward. They ask, what new possibilities and alliances arise? What new forms of activism or coalition can we create? What are our prospects for well-being? In short, what have we got if we ain't got health? Against Health ultimately argues that the conversations doctors, patients, politicians, activists, consumers, and policymakers have about health are enriched by recognizing that, when talking about health, they are not all talking about the same thing. And, that articulating the disparate valences of "health" can lead to deeper, more productive, and indeed more healthy interactions about our bodies.

    In this book, the 24-year history of this event is covered in detail, with all known runners and their results listed. Numerous photographs, charts, and maps are included. The runners have had some interesting experiences out there during the Barkley races. Some of those experiences have been humorous, some dramatic and harrowing. Many physical and psychological obstacles have been incorporated into the design of the event to test the limits of human endurance. The result is that most runners fail to finish the race. The stories in this book describe the epic struggles of the Barkley contestants, including some of the world's best endurance runners, against this extreme challenge. Tales From Out There will captivate the reader with true stories of both heartbreaking failures and awe-inspiring victories.