It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.

    Several resources exist for individual pieces of this data science stack, but only with the Python Data Science Handbook do you get them all—IPython, NumPy, Pandas, Matplotlib, Scikit-Learn, and other related tools.Working scientists and data crunchers familiar with reading and writing Python code will find this comprehensive desk reference ideal for tackling day-to-day issues: manipulating, transforming, and cleaning data; visualizing different types of data; and using data to build statistical or machine learning models. Quite simply, this is the must-have reference for scientific computing in Python.With this handbook, you’ll learn how to use: * IPython and Jupyter: provide computational environments for data scientists using Python * NumPy: includes the ndarray for efficient storage and manipulation of dense data arrays in Python * Pandas: features the DataFrame for efficient storage and manipulation of labeled/columnar data in Python * Matplotlib: includes capabilities for a flexible range of data visualizations in Python * Scikit-Learn: for efficient and clean Python implementations of the most important and established machine learning algorithms

    These areas of knowledge have converged into a modern theory of epidemiology that has been slow to penetrate into textbooks, particularly at the introductory level. Epidemiology: An Introduction closes the gap. It begins with a brief, lucid discussion of causal thinking and causal inference and then takes the reader through the elements of epidemiology, focusing on the measures of disease occurrence and causal effects. With these building blocks in place, the reader learns how to design, analyze and interpret problems that epidemiologists face, including confounding, the role of chance, and the exploration of interactions. All these topics are layered on the foundation of basic principles presented in simple language, with numerous examples and questions for further thought.

    Over years of groundbreaking experiments, he has distilled remarkable discoveries significant enough to become the bedrock of a whole new scientific field: social physics. Humans have more in common with bees than we like to admit: We’re social creatures first and foremost. Our most important habits of action—and most basic notions of common sense—are wired into us through our coordination in social groups. Social physics is about idea flow, the way human social networks spread ideas and transform those ideas into behaviors. Thanks to the millions of digital bread crumbs people leave behind via smartphones, GPS devices, and the Internet, the amount of new information we have about human activity is truly profound. Until now, sociologists have depended on limited data sets and surveys that tell us how people say they think and behave, rather than what they actually do. As a result, we’ve been stuck with the same stale social structures—classes, markets—and a focus on individual actors, data snapshots, and steady states. Pentland shows that, in fact, humans respond much more powerfully to social incentives that involve rewarding others and strengthening the ties that bind than incentives that involve only their own economic self-interest. Pentland and his teams have found that they can study patterns of information exchange in a social network without any knowledge of the actual content of the information and predict with stunning accuracy how productive and effective that network is, whether it’s a business or an entire city. We can maximize a group’s collective intelligence to improve performance and use social incentives to create new organizations and guide them through disruptive change in a way that maximizes the good. At every level of interaction, from small groups to large cities, social networks can be tuned to increase exploration and engagement, thus vastly improving idea flow.  Social Physics will change the way we think about how we learn and how our social groups work—and can be made to work better, at every level of society. Pentland leads readers to the edge of the most important revolution in the study of social behavior in a generation, an entirely new way to look at life itself.

    The Seventh Edition updates and revises material to reflect current advances in respiratory science but does not stray from the proven formula students and faculty have enjoyed since 1974.New updates include physiology of pulmonary capillaries, hypoxic pulmonary vasoconstriction, pulmonary edema, surface tension, elastic properties of the lung and chest wall, metabolic functions of the lung, and perinatal respiration. Ample illustrations and pedagogical features help clarify important equations and concepts. USMLE-style review questions at the end of each chapter help students review for class or boards.

    Even after more than three centuries and the revolutions of Einsteinian relativity and quantum mechanics, Newtonian physics continues to account for many of the phenomena of the observed world, and Newtonian celestial dynamics is used to determine the orbits of our space vehicles.This completely new translation, the first in 270 years, is based on the third (1726) edition, the final revised version approved by Newton; it includes extracts from the earlier editions, corrects errors found in earlier versions, and replaces archaic English with contemporary prose and up-to-date mathematical forms. Newton's principles describe acceleration, deceleration, and inertial movement; fluid dynamics; and the motions of the earth, moon, planets, and comets. A great work in itself, the Principia also revolutionized the methods of scientific investigation. It set forth the fundamental three laws of motion and the law of universal gravity, the physical principles that account for the Copernican system of the world as emended by Kepler, thus effectively ending controversy concerning the Copernican planetary system.The illuminating Guide to the Principia by I. Bernard Cohen, along with his and Anne Whitman's translation, will make this preeminent work truly accessible for today's scientists, scholars, and students.

    The material is arranged chronologically beginning with archaic origins and covers Egyptian, Mesopotamian, Greek, Chinese, Indian, Arabic and European contributions done to the nineteenth century and present day. There are revised references and bibliographies and revised and expanded chapters on the nineteeth and twentieth centuries.

    But building a machine learning system requires that you make practical decisions: Should you collect more training data? Should you use end-to-end deep learning? How do you deal with your training set not matching your test set? and many more. Historically, the only way to learn how to make these "strategy" decisions has been a multi-year apprenticeship in a graduate program or company. This is a book to help you quickly gain this skill, so that you can become better at building AI systems.

    Social Network Analysis: Methods and Applications reviews and discusses methods for the analysis of social networks with a focus on applications of these methods to many substantive examples. As the first book to provide a comprehensive coverage of the methodology and applications of the field, this study is both a reference book and a textbook.

    The book teaches a range of design and analysis techniques for problems that arise in computing applications. The text encourages an understanding of the algorithm design process and an appreciation of the role of algorithms in the broader field of computer science.

    A wealth of accompanying figures and exercises illustrate and develop the material in more depth. They describe what a quantum computer is, how it can be used to solve problems faster than familiar "classical" computers, and the real-world implementation of quantum computers. Their book concludes with an explanation of how quantum states can be used to perform remarkable feats of communication, and of how it is possible to protect quantum states against the effects of noise.

    

    Authors Drew Conway and John Myles White help you understand machine learning and statistics tools through a series of hands-on case studies, instead of a traditional math-heavy presentation.Each chapter focuses on a specific problem in machine learning, such as classification, prediction, optimization, and recommendation. Using the R programming language, you'll learn how to analyze sample datasets and write simple machine learning algorithms. "Machine Learning for Hackers" is ideal for programmers from any background, including business, government, and academic research.Develop a naive Bayesian classifier to determine if an email is spam, based only on its textUse linear regression to predict the number of page views for the top 1,000 websitesLearn optimization techniques by attempting to break a simple letter cipherCompare and contrast U.S. Senators statistically, based on their voting recordsBuild a "whom to follow" recommendation system from Twitter data

    Lavishly illustrated with engravings, woodcuts, and original drawings and diagrams, Sciencia will inspire readers of all ages to take an interest in the interconnected knowledge of the modern sciences.Beautifully produced in thirteen different colors of ink, Sciencia is an essential reference and an elegant gift.Wooden Books was founded in 1999 by designer John Martineau near Hay-on-Wye. The aim was to produce a beautiful series of recycled books based on the classical philosophies, arts and sciences. Using the Beatrix Potter formula of text facing picture pages, and old-styles fonts, along with hand-drawn illustrations and 19th century engravings, the books are designed not to date. Small but stuffed with information. Eco friendly and educational. Big ideas in a tiny space. There are over 1,000,000 Wooden Books now in print worldwide and growing.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.