For two decades, historian Alice Dreger has led a life of extraordinary engagement, combining activist service to victims of unethical medical research with defense of scientists whose work has outraged identity politics activists. With spirit and wit, Dreger offers in Galileo’s Middle Finger an unforgettable vision of the importance of rigorous truth seeking in today’s America, where both the free press and free scholarly inquiry struggle under dire economic and political threats.This illuminating chronicle begins with Dreger’s own research into the treatment of people born intersex (once called hermaphrodites). Realization of the shocking surgical and ethical abuses conducted in the name of “normalizing” intersex children’s gender identities moved Dreger to become an internationally recognized patient rights’ activist. But even as the intersex rights movement succeeded, Dreger began to realize how some fellow progressive activists were employing lies and personal attacks to silence scientists whose data revealed uncomfortable truths about humans. In researching one such case, Dreger suddenly became the target of just these kinds of attacks.Troubled, she decided to try to understand more—to travel the country to ferret out the truth behind various controversies, to obtain a global view of the nature and costs of these battles. Galileo’s Middle Finger describes Dreger’s long and harrowing journeys between the two camps for which she felt equal empathy: social justice activists determined to win and researchers determined to put hard truths before comfort. Ultimately what emerges is a lesson about the intertwining of justice and of truth—and a lesson of the importance of responsible scholars and journalists to our fragile democracy.

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

    But a very different civil rights history evolved at the Ionia State Hospital for the Criminally Insane in Ionia, Michigan. In The Protest Psychosis, psychiatrist and cultural critic Jonathan Metzl tells the shocking story of how schizophrenia became the diagnostic term overwhelmingly applied to African American protesters at Ionia—for political reasons as well as clinical ones. Expertly sifting through a vast array of cultural documents, Metzl shows how associations between schizophrenia and blackness emerged during the tumultuous decades of the 1960s and 1970s—and he provides a cautionary tale of how anxieties about race continue to impact doctor-patient interactions in our seemingly postracial America.From the Trade Paperback edition.

    Some system of authority is a requirement of all communal living, and it is only the man dwelling in isolation who is not forced to respond, through defiance or submission, to the commands of others. Obedience, as a determinant of behavior is of particular relevance to our time. It has been reliably established that from 1933 to 1945 millions of innocent people were systematically slaughtered on command. Gas chambers were built, death camps were guarded, daily quotas of corpses were produced with the same efficiency as the manufacture of appliances. These inhumane policies may have originated in the mind of a single person, but they could only have been carried out on a massive scale if a very large number of people obeyed orders.Obedience is the psychological mechanism that links individual action to political purpose. It is the dispositional cement that binds men to systems of authority. Facts of recent history and observation in daily life suggest that for many people obedience may be a deeply ingrained behavior tendency, indeed, a prepotent impulse overriding training in ethics, sympathy, and moral conduct. C. P. Snow (1961) points to its importance when he writes:When you think of the long and gloomy history of man, you will find more hideous crimes have been committed in the name of obedience than have ever been committed in the name of rebellion. If you doubt that, read William Sbirer's 'Rise and Fall of the Third Reich.' The German Officer Corps were brought up in the most rigorous code of obedience . . . in the name of obedience they were party to, andassisted in, the most wicked large scale actions in the history of the world. (p. 24)The Nazi extermination of European Jews is the most extremeinstance of abhorrent immoral acts carried out by thousands ofpeople in the name of obedience. Yet in lesser degree this type ofthing is constantly recurring: ordinary citizens are ordered todestroy other people, and they do so because they consider ittheir duty to obey orders. Thus, obedience to authority, longpraised as a virtue, takes on a new aspect when it serves amalevolent cause; far from appearing as a virtue, it is transformedinto a heinous sin. Or is it?The moral question of whether one should obey when commands conflict with conscience was argued by Plato, dramatized in "Antigone," and treated to philosophic analysis in every historical epoch Conservative philosophers argue that the very fabric of society is threatened by disobedience, and even when the act prescribed by an authority is an evil one, it is better to carry out the act than to wrench at the structure of authority. Hobbes stated further that an act so executed is in no sense the responsibility of the person who carries it out but only of the authority that orders it. But humanists argue for the primacy of individual conscience in such matters, insisting that the moral judgments of the individual must override authority when the two are in conflict.The legal and philosophic aspects of obedience are of enormous import, but an empirically grounded scientist eventually comes to the point where he wishes to move from abstract discourse to the careful observation of concrete instances. In order to take a close look at the act of obeying, I set up a simple experimentat Yale University. Eventually, the experiment was to involve more than a thousand participants and would be repeated at several universities, but at the beginning, the conception was simple. A person comes to a psychological laboratory and is told to carry out a series of acts that come increasingly into conflict with conscience. The main question is how far the participant will comply with the experimenter's instructions before refusing to carry out the actions required of him.But the reader needs to know a little more detail about the experiment. Two people come to a psychology laboratory to take part in a study of memory and learning. One of them is designated as a "teacher" and the other a "learner." The experimenter explains that the study is concerned with the effects of punishment on learning. The learner is conducted into a room, seated in a chair, his arms strapped to prevent excessive movement, and an electrode attached to his wrist. He is told that he is to learn a list of word pairs; whenever he makes an error, be will receive electric shocks of increasing intensity.The real focus of the experiment is the teacher. After watching the learner being strapped into place, he is taken into the main experimental room and seated before an impressive shock generator. Its main feature is a horizontal line of thirty switches, ranging from 15 volts to 450 volts, in 15-volt increments. There are also verbal designations which range from Slight SHOCK to Danger--Severe SHOCK. The teacher is told that he is to administer the learning test to the man in the other room. When the learner responds correctly, the teacher moves on to the next item; when the other man gives an incorrectanswer, the teacher is to give him an electric shock. He is to start at the lowest shock level ( 15 volts) and to increase the level each time the man makes an error, going through 30 volts, 45 volts, and so on.The "teacher" is a genuinely naive subject who has come to the laboratory to participate in an experiment. The learner, or victim, is an actor who actually receives no shock at all. The point of the experiment is to see how far a person will proceed in a concrete and measurable situation in which he is ordered to inflict increasing pain on a protesting victim.

    Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?In this humane and illuminating challenge to defect models of depression, psychologist Jonathan Rottenberg argues that depression is a particularly severe outgrowth of our natural capacity for emotion. In other words, it is a low mood gone haywire. Drawing on recent developments in the science of mood—and his own harrowing depressive experience as a young adult—Rottenberg explains depression in evolutionary terms, showing how its dark pull arises from adaptations that evolved to help our ancestors ensure their survival. Moods, high and low, evolved to compel us to more efficiently pursue rewards. While this worked for our ancestors, our modern environment—in which daily survival is no longer a sole focus—makes it all too easy for low mood to slide into severe, long-lasting depression.Weaving together experimental and epidemiological research, clinical observations, and the voices of individuals who have struggled with depression, The Depths offers a bold new account of why depression endures—and makes a strong case for de-stigmatizing this increasingly common condition. In so doing, Rottenberg offers hope in the form of his own and other patients’ recovery, and points the way towards new paths for treatment.

    Warnings that depressive disorder is a leading cause of worldwide disability have been accompanied by a massive upsurge in the consumption of antidepressant medication, widespread screening for depression in clinics and schools, and a push to diagnose depression early, on the basis of just a few symptoms, in order to prevent more severe conditions from developing.In The Loss of Sadness, Allan V. Horwitz and Jerome C. Wakefield argue that, while depressive disorder certainly exists and can be a devastating condition warranting medical attention, the apparent epidemic in fact reflects the way the psychiatric profession has understood and reclassified normal human sadness as largely an abnormal experience. With the 1980 publication of the landmark third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), mental health professionals began diagnosing depression based on symptoms—such as depressed mood, loss of appetite, and fatigue—that lasted for at least two weeks. This system is fundamentally flawed, the authors maintain, because it fails to take into account the context in which the symptoms occur. They stress the importance of distinguishing between abnormal reactions due to internal dysfunction and normal sadness brought on by external circumstances. Under the current DSM classification system, however, this distinction is impossible to make, so the expected emotional distress caused by upsetting events—for example, the loss of a job or the end of a relationship—could lead to a mistaken diagnosis of depressive disorder. Indeed, it is this very mistake that lies at the root of the presumed epidemic of major depression in our midst.

    In Letters to a Young Therapist, Dr. Pipher shares what she has learned in thirty years as a therapist, helping warring families, alienated adolescents, and harried professionals restore peace and beauty to their lives. Letters to a Young Therapist gives voice to her practice with an exhilarating mix of storytelling and sharp-eyed observation. And while her letters are addressed to an imagined young therapist, every one of us can take something away from them. Long before "positive psychology" became a buzzword, Dr. Pipher practiced a refreshingly inventive therapy--fiercely optimistic, free of dogma or psychobabble, and laced with generous warmth and practical common sense. But not until now has this gifted healer described her unique perspective on how therapy can help us revitalize our emotional landscape in an increasingly stressful world. Whether she's recommending daily swims for a sluggish teenager, encouraging a timid husband to become bolder, or simply bearing witness to a bereaved parent's sorrow, Dr. Pipher's compassion and insight shine from every page of this thoughtful and engaging book.

    Through the eyes of her naive and inexperienced younger self, Byron shares remarkable stories inspired by the people she had the privilege to treat. Gripping, poignant, and full of daring black humor, this book reveals the frightening and challenging induction all mental health staff face and highlights their incredible commitment to their patients. It shares the tales of ordinary people with an amazing resilience to life's challenges.

    In a book of unprecedented scope, McGilchrist draws on a vast body of recent brain research, illustrated with case histories, to reveal that the difference is profound—not just this or that function, but two whole, coherent, but incompatible ways of experiencing the world. The left hemisphere is detail oriented, prefers mechanisms to living things & is inclined to self-interest. The right hemisphere has greater breadth, flexibility & generosity. This division helps explain the origins of music & language, & casts new light on the history of philosophy, as well as on some mental illnesses. The 2nd part of the book takes a journey thru the history of Western culture, illustrating the tension between these two worlds as revealed in the thought & belief of thinkers & artists, from Aeschylus to Magritte. He argues that, despite its inferior grasp of reality, the left hemisphere is increasingly taking precedence in the modern world, with potentially disastrous consequences.List of IllustrationsAcknowledgmentsIntroductionAsymmetry and the brain --What do the two hemispheres 'do'? --Language, truth and music --The nature of the two worlds --The primacy of the right hemisphere --The triumph of the left hemisphere --Imitation and the evolution of culture --The ancient world --The Renaissance and the Reformation --The Enlightenment --Romanticism and the Industrial Revolution --The modern and post-modern worldsConclusionNotes BibliographyIndex

    Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself.Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system.In Pain in America is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

    Randall never gave sleep much thought. That is, until he began sleepwalking. One midnight crash into a hallway wall sent him on an investigation into the strange science of sleep.In Dreamland, Randall explores the research that is investigating those dark hours that make up nearly a third of our lives. Taking readers from military battlefields to children’s bedrooms, Dreamland shows that sleep isn't as simple as it seems. Why did the results of one sleep study change the bookmakers’ odds for certain Monday Night Football games? Do women sleep differently than men? And if you happen to kill someone while you are sleepwalking, does that count as murder?This book is a tour of the often odd, sometimes disturbing, and always fascinating things that go on in the peculiar world of sleep. You’ll never look at your pillow the same way again.

    Daniel Goleman's brilliant report from the frontiers of psychology and neuroscience offers startling new insight into our "two minds"—the rational and the emotional—and how they together shape our destiny.Through vivid examples, Goleman delineates the five crucial skills of emotional intelligence, and shows how they determine our success in relationships, work, and even our physical well-being. What emerges is an entirely new way to talk about being smart. The best news is that "emotional literacy" is not fixed early in life. Every parent, every teacher, every business leader, and everyone interested in a more civil society, has a stake in this compelling vision of human possibility.From the Trade Paperback edition.

    An experienced therapist offers groundbreaking and compassionate techniques for helping chronically inflexible children, who suffer from excessively immoderate tempers, showing how brain-based deficits contribute to these problems and offering positive and constructive ways to calm things down.

    But if you or someone you love is struggling with the frantic highs and crushing lows of this illness, there are still many hurdles to surmount at home, at work, and in daily life.*How can you learn to distinguish between the early warning signs of mood swings and the normal ups and downs of life? *What medications are available, and what are their side effects? *What should you do when you find yourself escalating into mania or descending into depression? *How can you get the help and support you need from family members and friends? *How can you tell your coworkers about your illness without endangering your career? In this comprehensive guide, Dr. David J. Miklowitz offers straight talk that can help you tackle these and related questions, take charge of your illness, and reclaim your life. A leading researcher and clinical specialist who knows what works, Dr. Miklowitz supplies proven tools to help you achieve balance--and free yourself from the emotional and financial havoc that result when symptoms rule your life--without sacrificing your right to rich and varied emotional experiences.This essential resource will help you and your family members come to terms with the diagnosis, recognize early warning signs of manic or depressive episodes, cope with triggers of mood swings, resolve medication problems, and learn to collaborate effectively with doctors and therapists. You'll learn specific ways to ask for support and help from your family and friends--and what to do when their "caring" feels like "controlling." For times when the going gets tough, a wealth of examples of how others have dealt with similar challenges offer new perspectives and new solutions.Whether you have recently been diagnosed with bipolar disorder, are considering seeking help for the first time, or have been in treatment for years, this empowering book is designed to help put you--not your illness--back in charge of your life.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.