Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself.Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system.In Pain in America is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

    Dr. Gad Saad, the host of the YouTube show THE SAAD TRUTH, exposes the bad ideas—what he calls “idea pathogens”—that are killing common sense and rational debate. Incubated in our universities and spread through the tyranny of political correctness, these ideas are endangering our most basic freedoms—including freedom of thought and speech. The danger is grave, but as Dr. Saad shows, politically correct dogma is riddled with logical fallacies. We have powerful weapons to fight back with—if we have the courage to use them. A provocative guide to defending reason and intellectual freedom and a battle cry for the preservation of our fundamental rights.

    J. Hollingdale's distinguished translation, together with a new historical introduction by Richard Schacht. Subtitled "A Book for Free Spirits," Human, All Too Human marked for Nietzsche a new "positivism" and skepticism with which he challenged his previous metaphysical and psychological assumptions. Nearly all the themes of his later work are displayed here with characteristic perceptiveness and honesty--not to say suspicion and irony--in language of great brio. It remains one of the fundamental works for an understanding of his thought.

    But how did this come about? And what does it mean for the future?Populism and ultra-nationalism brought about the rise of Hitler and Mussolini in the 1930s. Now, as Trump sits in the White House, Britain negotiates its way out of the EU, and countries across Europe see substantial gains in support for the extreme Right, award-winning journalist, author, and historian Gwynne Dyer asks how we got here, and where we go next. Dyer examines the global challenges facing us all today and explains how they have contributed to a world of inequality, poverty, and joblessness, conditions which he argues inevitably lead to the rise of populism. The greatest threat to social and political stability lies in the rise of automation, which will continue to eliminate jobs, whether politicians admit that it is happening or not. To avoid a social and political catastrophe, we will have to find ways of putting real money into the pockets of those who have no work. But this is not a book without hope. Our capacity for overcoming the worst has been tested again and again throughout history, and we have always survived. To do so now, Dyer argues, we must embrace radical solutions to the real difficulties facing individuals, or find ourselves back in the 1930s with no way out.

    Contrasting the views of medical science with those of ordinary women from diverse social and economic backgrounds, anthropologist Emily Martin presents unique fieldwork on American culture and uncovers the metaphors of economy and alienation that pervade women's imaging of themselves and their bodies. A new preface examines some of the latest medical ideas about women's reproductive cycles.

    In Pittsburgh, a child welfare agency uses a statistical model to try to predict which children might be future victims of abuse or neglect.Since the dawn of the digital age, decision-making in finance, employment, politics, health and human services has undergone revolutionary change. Today, automated systems—rather than humans—control which neighborhoods get policed, which families attain needed resources, and who is investigated for fraud. While we all live under this new regime of data, the most invasive and punitive systems are aimed at the poor.In Automating Inequality, Virginia Eubanks systematically investigates the impacts of data mining, policy algorithms, and predictive risk models on poor and working-class people in America. The book is full of heart-wrenching and eye-opening stories, from a woman in Indiana whose benefits are literally cut off as she lays dying to a family in Pennsylvania in daily fear of losing their daughter because they fit a certain statistical profile.The U.S. has always used its most cutting-edge science and technology to contain, investigate, discipline and punish the destitute. Like the county poorhouse and scientific charity before them, digital tracking and automated decision-making hide poverty from the middle-class public and give the nation the ethical distance it needs to make inhumane choices: which families get food and which starve, who has housing and who remains homeless, and which families are broken up by the state. In the process, they weaken democracy and betray our most cherished national values.This deeply researched and passionate book could not be more timely.Naomi Klein: "This book is downright scary."Ethan Zuckerman, MIT: "Should be required reading."Dorothy Roberts, author of Killing the Black Body: "A must-read for everyone concerned about modern tools of inequality in America."Astra Taylor, author of The People's Platform: "This is the single most important book about technology you will read this year."

    What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

    It’s time we stand face-to-digital-face with the true powers and limitations of the algorithms that already automate important decisions in healthcare, transportation, crime, and commerce. Hello World is indispensable preparation for the moral quandaries of a world run by code, and with the unfailingly entertaining Hannah Fry as our guide, we’ll be discussing these issues long after the last page is turned.

    We donate our time and money to charities and causes we deem worthy, choose careers we consider meaningful, and patronize businesses and buy products we believe make the world a better place. Unfortunately, we often base these decisions on assumptions and emotions rather than facts. As a result, even our best intentions often lead to ineffective—and sometimes downright harmful—outcomes. How can we do better? While a researcher at Oxford, trying to figure out which career would allow him to have the greatest impact, William MacAskill confronted this problem head on. He discovered that much of the potential for change was being squandered by lack of information, bad data, and our own prejudice. As an antidote, he and his colleagues developed effective altruism, a practical, data-driven approach that allows each of us to make a tremendous difference regardless of our resources. Effective altruists believe that it’s not enough to simply do good; we must do good better. At the core of this philosophy are five key questions that help guide our altruistic decisions: How many people benefit, and by how much? Is this the most effective thing I can do? Is this area neglected? What would have happened otherwise? What are the chances of success, and how good would success be? By applying these questions to real-life scenarios, MacAskill shows how many of our assumptions about doing good are misguided. For instance, he argues one can potentially save more lives by becoming a plastic surgeon rather than a heart surgeon; measuring overhead costs is an inaccurate gauge of a charity’s effectiveness; and, it generally doesn’t make sense for individuals to donate to disaster relief. MacAskill urges us to think differently, set aside biases, and use evidence and careful reasoning rather than act on impulse. When we do this—when we apply the head and the heart to each of our altruistic endeavors—we find that each of us has the power to do an astonishing amount of good.

    student, worked on a wartime project in microbiology professor Selman Waksman's lab, searching for an antibiotic to fight infections on the front lines and at home. In his eleventh experiment on a common bacterium found in farmyard soil, Schatz discovered streptomycin, the first effective cure for tuberculosis, one of the world's deadliest diseases.As director of Schatz's research, Waksman took credit for the discovery, belittled Schatz's work, and secretly enriched himself with royalties from the streptomycin patent filed by the pharmaceutical company Merck. In an unprecedented lawsuit, young Schatz sued Waksman, and was awarded the title of "co-discoverer" and a share of the royalties. But two years later, Professor Waksman alone was awarded the Nobel Prize. Schatz disappeared into academic obscurity.For the first time, acclaimed author and journalist Peter Pringle unravels the intrigues behind one of the most important discoveries in the history of medicine. The story unfolds on a tiny college campus in New Jersey, but its repercussions spread worldwide. The streptomycin patent was a breakthrough for the drug companies, overturning patent limits on products of nature and paving the way for today's biotech world. As dozens more antibiotics were found, many from the same family as streptomycin, the drug companies created oligopolies and reaped big profits. Pringle uses firsthand accounts and archives in the United States and Europe to reveal the intensely human story behind the discovery that started a revolution in the treatment of infectious diseases and shaped the future of Big Pharma.

     For several years, Andrew Marantz, a New Yorker staff writer, has been embedded in two worlds. The first is the world of social-media entrepreneurs, who, acting out of naïvete and reckless ambition, upended all traditional means of receiving and transmitting information. The second is the world of the people he calls "the gate crashers"—the conspiracists, white supremacists, and nihilist trolls who have become experts at using social media to advance their corrosive agenda. Antisocial ranges broadly—from the first mass-printed books to the trending hashtags of the present; from secret gatherings of neo-Fascists to the White House press briefing room—and traces how the unthinkable becomes thinkable, and then how it becomes reality. Combining the keen narrative detail of Bill Buford's Among the Thugs and the sweep of George Packer's The Unwinding, Antisocial reveals how the boundaries between technology, media, and politics have been erased, resulting in a deeply broken informational landscape—the landscape in which we all now live. Marantz shows how alienated young people are led down the rabbit hole of online radicalization, and how fringe ideas spread—from anonymous corners of social media to cable TV to the President's Twitter feed. Marantz also sits with the creators of social media as they start to reckon with the forces they've unleashed. Will they be able to solve the communication crisis they helped bring about, or are their interventions too little too late?

    A highly regarded scientist’s examination of the battle between evolution and intelligent design, and its implications for how science is practiced in America.

    The leading thinker on the topic of power, Pfeffer here distills his wisdom into an indispensable guide.” —Jim Collins, author of New York Times bestselling author Good to Great and How the Mighty FallSome people have it, and others don’t. Jeffrey Pfeffer explores why, in Power.One of the greatest minds in management theory and author or co-author of thirteen books, including the seminal business-school text Managing With Power, Jeffrey Pfeffer shows readers how to succeed and wield power in the real world.

    Reich makes the case for a generous, inclusive understanding of the American project, centering on the moral obligations of citizenship. Rooting his argument in everyday reality and common sense, Reich demonstrates the existence of a common good, and argues that it is this that defines a society or a nation. Societies and nations undergo virtuous cycles that reinforce and build the common good, as well as vicious cycles that undermine it. Over the course of the past five decades, Reich contends, America has been in a slowly accelerating vicious cycle--one that can and must be reversed. But first we need to weigh what really matters, and how we as a country should relate to honor, shame, patriotism, truth, and the meaning of leadership.Powerful, urgent, and utterly vital, this is a heartfelt missive from one of our foremost political thinkers: a fundamental statement about the purpose of society and a cri de coeur to save America's soul.

    In order for this to happen, the argument champions eating locally and sustainably and encourages those with the resources to grow their own food. Further examining the question of what to eat from the perspective of both human and environmental health, the account goes beyond health choices and discusses potential moral issues from eating—or not eating—animals. Through the deeply personal narrative of someone who practiced veganism for 20 years, this unique exploration also discusses alternatives to industrial farming, reveals the risks of a vegan diet, and explains why animals belong on ecologically sound farms.