The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them


Euan Angus Ashley - 2021
    Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Save Your Gallbladder and what to do if you've already lost it


Sandra Cabot - 2013
    A book to help everyone affected by disease of the gallbladder or bile ducts.If you are having gallbladder problems, whether you have already lost it or not, this book tells you what to do. Gallbladder disease can be painful and frightening, which explains why many people are rushed off to surgery to have their gallbladder removed. Is this the best thing to do? Are we panicking? These decisions are complex and serious and thus it takes an expert in liver and gallbladder problems like Dr Sandra Cabot to help you make sense of it.Your gallbladder is precious and supports optimal digestion and absorption of nutrients and some people have complications after surgery, some people still have the same pain after surgery some people never feel well after having their gallbladder removed.Thankfully, Dr Cabot has written this book to help you and your doctor make the best decisions.In most cases there are safe natural alternatives that can help you to save your gallbladder, dissolve stones and restore healthy gallbladder and liver function.In this book you will find the following information:Types of gallbladder disorders covered in this bookRisk factors for gallbladder diseaseSymptoms of gallbladder dysfunctionSymptoms of a gallbladder attackThe natural treatment of gallstonesThe seven essential strategies for treating gallbladder disease1. Keep the bile fluid and keep it moving - ie. prevent bile stasis and bile sludge2. The best foods and herbs for the gallbladderRaw vegetable juice for the gallbladderGreen goodness soup for the gallbladderRaw beetroot salad for the gallbladder3. Keep your bowel moving and avoid constipation4. Take the right nutrients necessary for healthy bile5. Reduce cholesterol6. Avoid problem foods and fix your digestionCoeliac disease and gallstonesFood allergies and gallstones7. Eat the right fatsFirst aid remedies for easing the pain of a gallbladder attackTo flush or not to flush: when is it safe and appropriate to do a gallbladder flush?Safe and effective gallbladder flushGallbladder remedies cheat sheetsummary of the most important pointsBasic structure and function of the gallbladderWhat goes wrong - why do gallstones form?Thick and stagnant bile - a recipe for stone formationDiagnosis of gallbladder diseaseBlood testsWhat if it’s not your gallbladder after all?The conventional medical treatment of gallstonesNon-surgical medical treatments for gallstonesSometimes it has to go!Signs and symptoms that indicate your gallbladder should come outOther conditions affecting the gallbladder or bile ducts.95Gallbladder conditions during pregnancyHow to live well without a gallbladderStrategies for maintaining good health without a gallbladderRecipes and Food IdeasSuper Quick Shopping Listwww.sandracabot.comwww.liverdoctor.comwww.cabothealth.com.au

The Bipolar Handbook: Real-Life Questions with Up-to-Date Answers


Wes Burgess - 2006
    Wes Burgess, the diagnosis of bipolar disorder means hope-hope for the estimated ten million people who will develop the disorder during their lifetimes, and hope for the families and friends of people who suffer from it. Drawing upon the real questions asked by patients and families during his nearly twenty years as a bipolar specialist, The Bipolar Handbook comprehensively tackles every area of the disorder, from its causes to medical treatment and psychotherapy, to strategies for creating a healthy lifestyle, to the prevention of, coping with, and treatment of bipolar episodes. From the more than five hundred questions and answers, you'll learn: - what to expect when pursuing a diagnosis- how to choose the right doctor or specialist- how to get the disorder under control- what treatments and medication protocols are best for you- how to reduce stress to prevent manic and depressive episodes- what family members and friends can do to support you, and more Dr. Burgess also addresses unique lifestyle concerns facing bipolar individuals. Special chapters on practical strategies for career success, building healthy relationships, issues that specifically affect bipolar women, and coping techniques for families and friends further explore the impact of the disorder on daily life. The Bipolar Handbook's easy-to-access format and full chapter of resources, as well as diagnostic criteria from the American Psychiatric Association and the National Institute for Mental Health, make this a versatile guide-perfect for quick reference and in-depth discovery.

Orthomolecular Medicine for Everyone: Megavitamin Therapeutics for Families and Physicians


Abram Hoffer - 2008
    Explains the basics of orthomolecular medicine, plus megavitamin therapy for arthritis, cancer, behavioral problems, and more.

Meth A Memoir


Wayne Huffman - 2012
    Written from within the confines of prison walls, the author gives an unflinching look at a life surrounded by drugs and drug use. It is a no holds barred, no feelings spared story that drags you, kicking and screaming, through the inner realms of the meth world. As an addict and meth cook, the author knows that there are aspects to the meth lifestyle that can only be understood by experiencing it for yourself. To help you understand this sub-culture, and those who call that world home, the author will take you into the meth world as no one else has ever done before. Everyone in America is affected by meth in one way or another. That simple fact makes this book a MUST READ.

The Ice Age: a journey into crystal-meth addiction


Luke Williams - 2016
    Over the next three months, he was seduced by the drug and descended into psychosis.This confronting and illuminating story charts Luke's recovery from the drug, and his investigation into its usage and prevalence in Australia and the western world. In examining what led to his addiction, Luke also explores the social problems that surround ice, scrutinising whether its abuse is in fact an epidemic, with what we're experiencing now merely the tip of the proverbial iceberg, or yet another moral panic about the underclass. Luke traces the history of methamphetamine from its legal usage in the early 20th century to its contemporary relevance as one of the most foreboding and talked-about illicit drugs in the world. His search for answers sees him exploring meth labs, interviewing addicts and law-enforcement officials, and witnessing firsthand the effects of the drug on individuals, families, and the healthcare system.Combining memoir with reportage, The Ice Age is a vital, compelling first-person account, and an investigation into a drug that is fast becoming the subject of national discussion throughout the western world.

Defeating the Ministers of Death: The compelling story of vaccination, one of medicine's greatest triumphs


David Isaacs - 2020
    In 1919, Spanish flu killed over 50 million people, more than died in both world wars combined. In 1950, an estimated 50 million people caught smallpox worldwide, of whom 10 million died. In 1980, before measles vaccine was widely used, an estimated 2.6 million children died of measles every year. Today we are hostage to a new pandemic disease -the seemingly unstoppable COVID-19.Less than 100 years ago, losing a child to an infection like diphtheria or polio was a dreaded but almost inevitable sorrow faced by all parents, from the richest to the poorest. Today, these killer diseases are almost never seen in industrialised countries, thanks to the development of vaccines. Immunisation has given modern parents peace of mind their ancestors could not imagine.The history of vaccination is rich with trial, error, sabotage and success. It encompasses the tragedy of lives lost, the drama of competition and discovery, the culpability of botched testing, and the triumph of effective, lifelong immunity. Yet with the eradication in the first world of some of humanity's deadliest foes, complacency in some quarters has set in. COVID-19 has us again racing for a vaccine. The story of past achievements and failures helps us keep the race - and the hope - in perspective.This is a book for everyone who wants to understand our past - and cares about our future.PRAISE'Anyone who has doubts about the life-saving miracle of vaccination should read this' Steven Carroll, Sydney Morning Herald'An entertaining and engaging work that is sure to delight general readers' Australian Book Review'The ideal handbook for pregnant women, parents, travellers, childcare and aged-care workers, GPs and anyone with an interest in public health' The Australian'Isaacs explores the understanding of immunity as it develops from the fifth century BC to the present day and thrills us with the progressive successes of each of the 14 vaccines which a child routinely receives today ... The work is authoritative, beguiling, amusing, instructive and inspirational. It deserves a wide readership, including infectious disease experts, other health professionals and, most assuredly, a diversity of lay people' Sir Gustav Nossal, immunologist and director of The Walter and Eliza Institute of Medical Research, Melbourne, 1965-1996'A rollicking story of human endeavour, error, misinformation, success and failure ... and more than a glimpse of why we need to continue to research, evaluate, educate and fund vaccines to prevent disease' Fiona Stanley, Distinguished Research Professor, University of Western Australia'Effortlessly accessible, Defeating the Ministers of Death brilliantly reveals the people behind the most important public health intervention in history' Professor Andrew J Pollard, Department of Paediatrics, University of Oxford'This book is an unflinching look at the triumphs and inevitable tragedies in the war against infectious diseases. Nonfiction is at its best when it reads like fiction. And David Isaacs has written a page turner' Paul A. Offit, MD, author of Bad Advice: Or Why Celebrities, Politicians, and Activists Aren't Your Best Source of Health Information

The Nocturnal Brain: Nightmares, Neuroscience, and the Secret World of Sleep


Guy Leschziner - 2019
    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

The Brain's Way of Healing: Remarkable Discoveries and Recoveries from the Frontiers of Neuroplasticity


Norman Doidge - 2015
    His revolutionary new book shows, for the first time, how the amazing process of neuroplastic healing really works. It describes natural, non-invasive avenues into the brain provided by the forms of energy around us—light, sound, vibration, movement—which pass through our senses and our bodies to awaken the brain’s own healing capacities without producing unpleasant side effects. Doidge explores cases where patients alleviated years of chronic pain or recovered from debilitating strokes or accidents; children on the autistic spectrum or with learning disorders normalizing; symptoms of multiple sclerosis, Parkinson’s disease, and cerebral palsy radically improved, and other near-miracle recoveries. And we learn how to vastly reduce the risk of dementia with simple approaches anyone can use. For centuries it was believed that the brain’s complexity prevented recovery from damage or disease. The Brain’s Way of Healing shows that this very sophistication is the source of a unique kind of healing. As he did so lucidly in The Brain That Changes Itself, Doidge uses stories to present cutting-edge science with practical real-world applications, and principles that everyone can apply to improve their brain’s performance and health.

Why We Get Sick: The New Science of Darwinian Medicine


Randolph M. Nesse - 1994
    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

How Doctors Think


Jerome Groopman - 2007
    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic


Ben Westhoff - 2019
    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

The Cost of Cutting: A Surgeon Reveals the Truth Behind a Multibillion-Dollar Industry


Paul A. Ruggieri - 2014
    Ruggieri reveals little-known truths about his profession—and the hidden flaws of our healthcare system—in this compelling and troubling account of real patients, real doctors, and how money influences medical decisions behind the scenes. Even many well-informed patients have no idea what may be contributing to the cost of their surgery. With up-to-date research and stories from his practice, Ruggieri shows how business arrangements among hospitals, insurance companies, and surgeons affect who gets treatment—and whether they get the right treatment. Pulling back the curtain from the hospital bed, he explains how to safeguard one’s own health (and finances), and how America can make surgery more affordable for all without sacrificing quality care.

Selling Sickness: How the World's Biggest Pharmaceutical Companies are Turning Us All into Patients


Ray Moynihan - 2005
    Suggesting he would like Merck to be more like the maker of Wrigley's chewing gum, the CEO said it had long been his dream to make drugs for healthy people, to "sell to everyone." That dream now drives the marketing machinery of the most profitable industry on earth. From award-winning Ray Moynihan,—one of the world's top medical journalists—Selling Sickness reveals how widening the boundaries of illness and lowering the threshold for treatments is creating millions of new patients and billions in new profits. This in turn is driving up personal drug bills and threatening to bankrupt national health systems all over the world. As more and more ordinary life is "medicalized," the industry moves ever closer to being able to "sell to everyone."

Surgery, The Ultimate Placebo: A Surgeon Cuts through the Evidence


Ian Harris - 2016
    In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.