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Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids by Richard Durbin
biology
science
bioinformatics
reference
Biochemistry
Jeremy M. Berg - 1975
In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design. Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas.
Data Mining: Practical Machine Learning Tools and Techniques
Ian H. Witten - 1999
This highly anticipated fourth edition of the most ...Download Link : readmeaway.com/download?i=0128042915 0128042915 Data Mining: Practical Machine Learning Tools and Techniques (Morgan Kaufmann Series in Data Management Systems) PDF by Ian H. WittenRead Data Mining: Practical Machine Learning Tools and Techniques (Morgan Kaufmann Series in Data Management Systems) PDF from Morgan Kaufmann,Ian H. WittenDownload Ian H. Witten's PDF E-book Data Mining: Practical Machine Learning Tools and Techniques (Morgan Kaufmann Series in Data Management Systems)
Convex Optimization
Stephen Boyd - 2004
A comprehensive introduction to the subject, this book shows in detail how such problems can be solved numerically with great efficiency. The focus is on recognizing convex optimization problems and then finding the most appropriate technique for solving them. The text contains many worked examples and homework exercises and will appeal to students, researchers and practitioners in fields such as engineering, computer science, mathematics, statistics, finance, and economics.
Computer Science Illuminated
Nell B. Dale - 2002
Written By Two Of Today'S Most Respected Computer Science Educators, Nell Dale And John Lewis, The Text Provides A Broad Overview Of The Many Aspects Of The Discipline From A Generic View Point. Separate Program Language Chapters Are Available As Bundle Items For Those Instructors Who Would Like To Explore A Particular Programming Language With Their Students. The Many Layers Of Computing Are Thoroughly Explained Beginning With The Information Layer, Working Through The Hardware, Programming, Operating Systems, Application, And Communication Layers, And Ending With A Discussion On The Limitations Of Computing. Perfect For Introductory Computing And Computer Science Courses, Computer Science Illuminated, Third Edition's Thorough Presentation Of Computing Systems Provides Computer Science Majors With A Solid Foundation For Further Study, And Offers Non-Majors A Comprehensive And Complete Introduction To Computing.
The Pragmatic Programmer: From Journeyman to Master
Andy Hunt - 1999
It covers topics ranging from personal responsibility and career development to architectural techniques for keeping your code flexible and easy to adapt and reuse. Read this book, and you'll learn how toFight software rot; Avoid the trap of duplicating knowledge; Write flexible, dynamic, and adaptable code; Avoid programming by coincidence; Bullet-proof your code with contracts, assertions, and exceptions; Capture real requirements; Test ruthlessly and effectively; Delight your users; Build teams of pragmatic programmers; and Make your developments more precise with automation. Written as a series of self-contained sections and filled with entertaining anecdotes, thoughtful examples, and interesting analogies,
The Pragmatic Programmer
illustrates the best practices and major pitfalls of many different aspects of software development. Whether you're a new coder, an experienced programmer, or a manager responsible for software projects, use these lessons daily, and you'll quickly see improvements in personal productivity, accuracy, and job satisfaction. You'll learn skills and develop habits and attitudes that form the foundation for long-term success in your career. You'll become a Pragmatic Programmer.
Numerical Recipes in C: The Art of Scientific Computing
William H. Press - 1988
In a self-contained manner it proceeds from mathematical and theoretical considerations to actual practical computer routines. With over 100 new routines bringing the total to well over 300, plus upgraded versions of the original routines, the new edition remains the most practical, comprehensive handbook of scientific computing available today.
Grokking Deep Learning
Andrew W. Trask - 2017
Loosely based on neuron behavior inside of human brains, these systems are rapidly catching up with the intelligence of their human creators, defeating the world champion Go player, achieving superhuman performance on video games, driving cars, translating languages, and sometimes even helping law enforcement fight crime. Deep Learning is a revolution that is changing every industry across the globe.Grokking Deep Learning is the perfect place to begin your deep learning journey. Rather than just learn the “black box” API of some library or framework, you will actually understand how to build these algorithms completely from scratch. You will understand how Deep Learning is able to learn at levels greater than humans. You will be able to understand the “brain” behind state-of-the-art Artificial Intelligence. Furthermore, unlike other courses that assume advanced knowledge of Calculus and leverage complex mathematical notation, if you’re a Python hacker who passed high-school algebra, you’re ready to go. And at the end, you’ll even build an A.I. that will learn to defeat you in a classic Atari game.
Introduction to Machine Learning with Python: A Guide for Data Scientists
Andreas C. Müller - 2015
If you use Python, even as a beginner, this book will teach you practical ways to build your own machine learning solutions. With all the data available today, machine learning applications are limited only by your imagination.You'll learn the steps necessary to create a successful machine-learning application with Python and the scikit-learn library. Authors Andreas Muller and Sarah Guido focus on the practical aspects of using machine learning algorithms, rather than the math behind them. Familiarity with the NumPy and matplotlib libraries will help you get even more from this book.With this book, you'll learn:Fundamental concepts and applications of machine learningAdvantages and shortcomings of widely used machine learning algorithmsHow to represent data processed by machine learning, including which data aspects to focus onAdvanced methods for model evaluation and parameter tuningThe concept of pipelines for chaining models and encapsulating your workflowMethods for working with text data, including text-specific processing techniquesSuggestions for improving your machine learning and data science skills
Database Systems: A Practical Approach to Design, Implementation and Management
Thomas M. Connolly - 1995
Meant for students and professionals, it includes explanations using case studies. The design methodology is divided into conceptual, logical, and physical.
Scale: The Universal Laws of Growth, Innovation, Sustainability, and the Pace of Life in Organisms, Cities, Economies, and Companies
Geoffrey B. West - 2017
The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.
Getting Started with SQL: A Hands-On Approach for Beginners
Thomas Nield - 2016
If you're a business or IT professional, this short hands-on guide teaches you how to pull and transform data with SQL in significant ways. You will quickly master the fundamentals of SQL and learn how to create your own databases.Author Thomas Nield provides exercises throughout the book to help you practice your newfound SQL skills at home, without having to use a database server environment. Not only will you learn how to use key SQL statements to find and manipulate your data, but you'll also discover how to efficiently design and manage databases to meet your needs.You'll also learn how to:Explore relational databases, including lightweight and centralized modelsUse SQLite and SQLiteStudio to create lightweight databases in minutesQuery and transform data in meaningful ways by using SELECT, WHERE, GROUP BY, and ORDER BYJoin tables to get a more complete view of your business dataBuild your own tables and centralized databases by using normalized design principlesManage data by learning how to INSERT, DELETE, and UPDATE records
Automate This: How Algorithms Came to Rule Our World
Christopher Steiner - 2012
It used to be that to diagnose an illness, interpret legal documents, analyze foreign policy, or write a newspaper article you needed a human being with specific skills—and maybe an advanced degree or two. These days, high-level tasks are increasingly being handled by algorithms that can do precise work not only with speed but also with nuance. These “bots” started with human programming and logic, but now their reach extends beyond what their creators ever expected. In this fascinating, frightening book, Christopher Steiner tells the story of how algorithms took over—and shows why the “bot revolution” is about to spill into every aspect of our lives, often silently, without our knowledge. The May 2010 “Flash Crash” exposed Wall Street’s reliance on trading bots to the tune of a 998-point market drop and $1 trillion in vanished market value. But that was just the beginning. In Automate This, we meet bots that are driving cars, penning haiku, and writing music mistaken for Bach’s. They listen in on our customer service calls and figure out what Iran would do in the event of a nuclear standoff. There are algorithms that can pick out the most cohesive crew of astronauts for a space mission or identify the next Jeremy Lin. Some can even ingest statistics from baseball games and spit out pitch-perfect sports journalism indistinguishable from that produced by humans. The interaction of man and machine can make our lives easier. But what will the world look like when algorithms control our hospitals, our roads, our culture, and our national security? What happens to businesses when we automate judgment and eliminate human instinct? And what role will be left for doctors, lawyers, writers, truck drivers, and many others? Who knows—maybe there’s a bot learning to do your job this minute.
iGenetics: A Molecular Approach
Peter J. Russell - 2001
Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics
Discovering Statistics Using R
Andy Field - 2012
Like its sister textbook, Discovering Statistics Using R is written in an irreverent style and follows the same ground-breaking structure and pedagogical approach. The core material is enhanced by a cast of characters to help the reader on their way, hundreds of examples, self-assessment tests to consolidate knowledge, and additional website material for those wanting to learn more.
Clean Code: A Handbook of Agile Software Craftsmanship
Robert C. Martin - 2007
But if code isn't clean, it can bring a development organization to its knees. Every year, countless hours and significant resources are lost because of poorly written code. But it doesn't have to be that way. Noted software expert Robert C. Martin presents a revolutionary paradigm with Clean Code: A Handbook of Agile Software Craftsmanship . Martin has teamed up with his colleagues from Object Mentor to distill their best agile practice of cleaning code on the fly into a book that will instill within you the values of a software craftsman and make you a better programmer but only if you work at it. What kind of work will you be doing? You'll be reading code - lots of code. And you will be challenged to think about what's right about that code, and what's wrong with it. More importantly, you will be challenged to reassess your professional values and your commitment to your craft. Clean Code is divided into three parts. The first describes the principles, patterns, and practices of writing clean code. The second part consists of several case studies of increasing complexity. Each case study is an exercise in cleaning up code - of transforming a code base that has some problems into one that is sound and efficient. The third part is the payoff: a single chapter containing a list of heuristics and "smells" gathered while creating the case studies. The result is a knowledge base that describes the way we think when we write, read, and clean code. Readers will come away from this book understanding ‣ How to tell the difference between good and bad code‣ How to write good code and how to transform bad code into good code‣ How to create good names, good functions, good objects, and good classes‣ How to format code for maximum readability ‣ How to implement complete error handling without obscuring code logic ‣ How to unit test and practice test-driven development This book is a must for any developer, software engineer, project manager, team lead, or systems analyst with an interest in producing better code.