There's the pure and bounteous joy of the nail varnish museum. Not to mention the very best lies to tell if you find yourself on an Arctic cruise. She has words of advice for those fast approaching fifty. And she's here to tell you the secret secret truth about writers - well, this one anyway.You'll be wincing in recognition and scratching your head in incredulity, but like Marian herself you won't be able to stop laughing at the sheer delightful absurdity that is modern life - because each and every one of us is clearly making it up as we go along.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Animal combines autobiography and evolutionary history to create a funny, fascinating insight into the forces that mould and affect modern women.Animal is entertaining and informative, personal and universal – silly about lots of things and serious about some. It's a laugh-out-loud investigation to help us understand and forgive our animal urges and insecurities.

    When Matt Haig developed panic disorder, anxiety, and depression as an adult, it took him a long time to work out the ways the external world could impact his mental health in both positive and negative ways. Notes on a Nervous Planet collects his observations, taking a look at how the various social, commercial and technological "advancements" that have created the world we now live in can actually hinder our happiness. Haig examines everything from broader phenomena like inequality, social media, and the news; to things closer to our daily lives, like how we sleep, how we exercise, and even the distinction we draw between our minds and our bodies.

    A legion of dedicated fans had lost their idol; a devastated family had lost their Amy. With this difficult news came an outpouring of love and grief from her fans, along with troubling questions about Amy's very public struggles with drugs and alcohol, as people tried to understand how such a soulful singer had been silenced so young.Now, in this intimate and tender account, her father and confidant, Mitch, offers an inside view of Amy's life as she lived it, putting to rest once and for all the controversies that have long surrounded her. Sifting fact from fiction, he pre-sents a portrait of Amy unlike any other, detailing the events and the people that shaped her youth--from her mischievous childhood to her grandmother's Jazz Age stories, to her father singing Frank Sinatra around the house. Shedding light on Amy's musical coming-of-age, Mitch explores how she honed her distinctive sound, created her unforgettable look, and channeled her own life into hits such as "You Know I'm No Good," "Rehab," and "Back to Black"--some of the most memorable and personal pop music in years.While her beehive hair, larger-than-life voice, and outrageous personality made her famous, her life offstage made her infamous. Here Mitch holds nothing back about Amy's addiction to drugs and alcohol, mixing the painful with the poignant as he describes the realities of her dependencies and the toll they took on the family and friends who refused to give up on her. Revealing the truth about Amy's substance abuse and dispelling many of the tabloid-fueled rumors about her tumultuous marriage to Blake Fielder-Civil, Mitch exposes the years of behind-the-scenes drama that consumed his life and explains how, for those who knew Amy in her last months, the greatest tragedy of all was that she finally appeared to be conquering her demons.Filled with insights into Amy Winehouse's music, photographs from her life, and stories of the real woman behind the headlines, "Amy, My Daughter" is an emotional journey into music, addiction, and the unbreakable bond between a daughter and her father.

    As with other illnesses, the approaches most likely to work are based on science — not on faith, tradition, contrition, or wishful thinking. These facts are the foundation of Clean. The existing addiction treatments, including Twelve Step programs and rehabs, have helped some, but they have failed to help many more. To discover why, David Sheff spent time with scores of scientists, doctors, counselors, and addicts and their families, and explored the latest research in psychology, neuroscience, and medicine. In Clean, he reveals how addiction really works, and how we can combat it.“A guide for those affected by addiction, but also a manifesto . . . for America as it confronts its drug problem. [Sheff] has performed a vital service by compiling sensible advice on a subject for which sensible advice is in short supply.” — New York Times Book Review“As a journalist, father, and clear-eyed chronicler of addiction, David Sheff is without peer.” — Sanjay Gupta, M.D., chief medical correspondent, CNN

    You can’t help but fall for Chika. A page-turner that will no doubt become a classic.” --Mary Karr, author of The Liars’ Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom’s most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart.  Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika’s arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, “No one in Haiti can help you with.” Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika’s boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed—a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

    She knew the change wouldn't be easy but she never expected to find herself an overweight, depressed, middle-aged mother of three who was drinking more than a bottle of wine a day, and spending her evenings Googling 'Am I an alcoholic?' This book is the bravely honest story of a year in Clare's life. A year that started with her quitting booze and then being given the devastating diagnosis of breast cancer. By the end of the year she is booze-free and cancer-free, she no longer has a wine belly, is two stone lighter and with a life that is so much richer, healthier and more rewarding than ever before. She has a happier family and a more positive outlook. Sober Diaries is an upbeat, funny and positive look at how to live life to the full. Interwoven within Clare's own very personal and brilliantly comic story is research and advice as she discovers the answers to questions like: How do I know if I'm drinking too much? How will I cope at parties? What do I say to friends and family? How do I cope with cravings? If I stop drinking will I lose weight? What if my partner still drinks? And many more.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    The memoir of a woman, tricked and trapped into sexual slavery as a young teenager.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    Dr. Eben Alexander was one of those scientists. A highly trained neurosurgeon, Alexander knew that NDEs feel real, but are simply fantasies produced by brains under extreme stress.Then, Dr. Alexander’s own brain was attacked by a rare illness. The part of the brain that controls thought and emotion—and in essence makes us human—shut down completely. For seven days he lay in a coma. Then, as his doctors considered stopping treatment, Alexander’s eyes popped open. He had come back.Alexander’s recovery is a medical miracle. But the real miracle of his story lies elsewhere. While his body lay in coma, Alexander journeyed beyond this world and encountered an angelic being who guided him into the deepest realms of super-physical existence. There he met, and spoke with, the Divine source of the universe itself.Alexander’s story is not a fantasy. Before he underwent his journey, he could not reconcile his knowledge of neuroscience with any belief in heaven, God, or the soul. Today Alexander is a doctor who believes that true health can be achieved only when we realize that God and the soul are real and that death is not the end of personal existence but only a transition.This story would be remarkable no matter who it happened to. That it happened to Dr. Alexander makes it revolutionary. No scientist or person of faith will be able to ignore it. Reading it will change your life.

      A brilliant stylist known for an uncompromising honesty that challenges conventional wisdom at every turn, Krauthammer has for decades daz­zled readers with his keen insight into politics and government. His weekly column is a must-read in Washington and across the country. Now, finally, the best of Krauthammer’s intelligence, erudition and wit are collected in one volume.   Readers will find here not only the country’s leading conservative thinker offering a pas­sionate defense of limited government, but also a highly independent mind whose views—on feminism, evolution and the death penalty, for example—defy ideological convention. Things That Matter also features several of Krautham­mer’s major path-breaking essays—on bioeth­ics, on Jewish destiny and on America’s role as the world’s superpower—that have pro­foundly influenced the nation’s thoughts and policies. And finally, the collection presents a trove of always penetrating, often bemused re­flections on everything from border collies to Halley’s Comet, from Woody Allen to Win­ston Churchill, from the punishing pleasures of speed chess to the elegance of the perfectly thrown outfield assist.   With a special, highly autobiographical in­troduction in which Krauthammer reflects on the events that shaped his career and political philosophy, this indispensible chronicle takes the reader on a fascinating journey through the fashions and follies, the tragedies and triumphs, of the last three decades of American life.

    A long-buried personal sadness is enfolding her—and her career is stalled—when she stumbles upon an unusual group of immigrants living in rural California. She follows them on their annual return to the remote Azorean islands in the Atlantic Ocean, where bulls run down village streets, volcanoes are active, and the people celebrate festas to ease their saudade, a longing so deep that the Portuguese word for it can’t be fully translated.Years later, California is in a terrible drought, the wildfires seem to never end, and Diana finds herself still dreaming of those islands and the chuva—a rain so soft you don’t notice when it begins or ends.With her troublesome Labrador retriever, Murphy, in tow, Diana returns to the islands of her dreams only to discover that there are still things she longs for—and one of them may be a most unexpected love.

    But in her mother, a would-be artist burdened by the endless arrival of new babies, young Kate saw the consequences of a dream deferred. Determined to pursue her own no matter the cost, at 18 she left her small Midwestern town for New York, where, studying with the legendary Stella Adler, she learned the lesson that would define her as an actress: "Use it," Adler told her. Whatever disappointment, pain, or anger life throws in your path, channel it into the work.It was a lesson she would need. At twenty-two, just as her career was taking off, she became pregnant and gave birth to a daughter. Having already signed the adoption papers, she was allowed only a fleeting glimpse of her child. As her star continued to rise, her life became increasingly demanding and fulfilling, a whirlwind of passionate love affairs, life-saving friendships, and bone-crunching work. Through it all, Mulgrew remained haunted by the loss of her daughter, until, two decades later, she found the courage to face the past and step into the most challenging role of her life, both on and off screen.We know Kate Mulgrew for the strong women she's played--Captain Janeway on Star Trek; the tough-as-nails "Red" on Orange is the New Black. Now, we meet the most inspiring and memorable character of all: herself. By turns irreverent and soulful, laugh-out-loud funny and heart-piercingly sad, BORN WITH TEETH is the breathtaking memoir of a woman who dares to live life to the fullest, on her own terms.