That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    Thanks to the astonishing results it provides--glowing skin, a flatter stomach, enhanced immunity, and full-body detox--the practice of manually stimulating the lymphatic system has become one of the most popular wellness practices today. Lymphatic drainage works because the lymphatic system--a complex geography of rivers that snake throughout the body just beneath the surface of the skin--connects every other bodily system. When lymph flows, everything else flows, too.In this first-of-its-kind guide, veteran lymphatic drainage practitioner, educator, and advocate Lisa Levitt Gainsley explains how to maintain lymphatic health, sharing the five-minute self-massage techniques she originally developed for her high-powered Los Angeles clientele. These simple sequences are tailored to address a number of specific and common issues: bloating, headaches, digestive problems, immune health, anxiety, weight loss, acne, inflammation, and more.Whether you just want to look and feel your best or are facing a more serious health issue such as cancer treatment or recovery, The Book of Lymph offers educational and practical instruction to help you cultivate a body free of pain and lethargy, activate a calmer state of being, and boost overall glow--in just five minutes a day.

    An engineer by training, Bernstein pioneered blood glucose self-monitoring and the tight control of blood sugar that is now accepted as the standard treatment of diabetes.

    This encouraging change not only has benefited veterans but also provides a blueprint for salvaging America's own deeply troubled healthcare system. "Best Care Anywhere" shows how a government bureaucracy, working with little notice, is setting the standard for best practices and cost reduction while the private sector is lagging in both areas. Author Phillip Longman challenges conventional wisdom by explaining exactly how market forces work to lower quality and raise prices in the healthcare sector, and how U.S. medical practices have a weak basis in science. The book, expanded from a widely praised article in the "Washington Monthly," mixes hard facts with author Philip Longmans' compelling human story of the loss of his wife to cancer. Part manifesto, part moving memoir, "Best Care Anywhere" offers new hope for addressing a major problem of contemporary society that affects all of us.

     Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation? In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients—a Biotech Social Contract. Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including: Why doesn’t insurance make drugs affordable? How can we prevent price-jacking of older drugs? Why are drugs more expensive in America than elsewhere? How can we guarantee that all medicines eventually go generic so they are only temporarily expensive? What systemic failures led to the opioid crisis, and how can we prevent the next one? The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.

    Now she turns her investigative skills to a controversial case that exposed the increased suicide rates among adolescents taking antidepressants such as Paxil, Prozac, and Zoloft.Side Effects tells the tale of a gutsy assistant attorney general who, along with an unlikely whistle-blower at an Ivy League university, uncovered evidence of deception behind one of the most successful drug campaigns in history. Paxil was the world's bestselling antidepressant in 2002. Pediatric prescriptions soared, even though there was no proof that the drug performed any better than sugar pills in treating children and adolescents, and the real risks the drugs posed were withheld from the public. The New York State Attorney General's office brought an unprecedented lawsuit against giant manufacturer GlaxoSmithKline, the maker of Paxil, for consumer fraud. The successful suit launched a tidal wave of protest that changed the way drugs are tested, sold, and marketed in this country. With meticulous research, Alison Bass shows us the underbelly of the pharmaceutical industry. She lays bare the unhealthy ties between the medical establishment, big pharma, and the FDA—relationships that place vulnerable children and adults at risk every day.

    No matter what you’ve heard, there are always steps you can take to help your dog fight (and even beat) cancer. This scientifically researched guide is your complete reference for practical, evidence-based strategies that can optimize the life quality and longevity for your dog. No matter what diagnosis or stage of cancer your dog has, this book is packed with precious advice that can help now. Discover the Full Spectrum approach to dog cancer care: * Everything you need to know about conventional western veterinary treatments (surgery, chemotherapy and radiation) including how to reduce their side effects. * The most effective non-conventional options, including botanical nutraceuticals, supplements, nutrition, and mind-body medicine. * How to analyze the options and develop a specific plan for your own dog based on your dog’s type of cancer, your dog’s age, your financial and time budget, your personality, and many other personal factors. Imagine looking back at this time in your life, five years from now, and having not a single regret. You can help your dog fight cancer and you can honor your dog’s life by living each moment to the fullest, starting now. This book can help you as it has helped thousands of other dog lovers. THE AUTHORS Dr. Demian Dressler, DVM practices in Hawaii and is internationally recognized as "the dog cancer vet" Dr. Susan Ettinger, DVM is a veterinary oncologist and a diplomate of the American College of Internal Medicine who practices in New York. PRAISE FROM VETERINARIANS, AUTHORS & BOOK REVIEWERS"The future is upon us and this ground-breaking book is a vital cornerstone. In dealing with cancer, our worst illness, this Survival Guide is educational, logical, expansive, embracing, honest and so needed." -Dr. Marty Goldstein, DVMHolistic veterinarian and Host, Ask Martha Stewart’s Vet on Sirius Radio "The message of this book jumps off the written page and into the heart of every reader, and will become the at home bible for cancer care of dogs. The authors have given you a sensible and systematic approach that practicing veterinarians will cherish. I found the book inspiring and, clearly, it will become part of my daily approach to cancer therapy for my own patients." -Dr. Robert B. Cohen, VMD Bay Street Animal Hospital, New York "I wish that I had had The Dog Cancer Survival Guide when my dearly beloved Flat-coated Retriever, Odin, contracted cancer. It would have provided me alternative courses of action, as well as some well needed "reality checks" which were not available from conversations with my veterinarian. It should be on every dog owner’s book shelf--just in case..." -Dr. Stanley Coren, PhD, FRSC author of many books, including Born to Bark "A comprehensive guide that distills both alternative and allopathic cancer treatments in dogs...With the overwhelming amount of conflicting information about cancer prevention and treatment, this book provides a pet owner with an easy to follow approach to one of the most serious diseases in animals." -Dr. Barbara Royal, DVM The Royal Treatment Veterinary Center, Oprah Winfrey’s Chicago veterinarian "Picking up The Dog Cancer Survival Guide is anything but a downer: it's an 'empowerer.' It will make you feel like the best medical advocate for your dog. It covers canine cancer topics to an unprecedented depth and breadth from emotional coping strategies to prevention-in plain English.

    Gilbert WelchRead Overdiagnosed: Making People Sick in the Pursuit of Health PDF from Beacon Press,H. Gilbert WelchDownload H. Gilbert Welch's PDF E-book Overdiagnosed: Making People Sick in the Pursuit of Health

    The book's holistic perspective shows students how nursing care involves more than performing procedures. With a case-based approach to learning, the book offers numerous examples and opportunities for students to think critically. The Seventh Edition includes new features highlighting clinical questions and research, nursing advocacy, and health literacy, and also includes new information related to electronic medical records and documentation. With this textbook you'll find an integrated, cohesive, and student-focused suite of multimedia products to appeal to all types of learners, including a bound-in DVD-ROM and a companion website.

    In The YouTube Formula: How Anyone Can Unlock the Algorithm to Drive Views, Build an Audience, and Grow Revenue, the owner of the largest YouTube how-to channel provides the secrets to getting the results that every YouTube creator and strategist wants. Eves will reveal what readers can't get anywhere else: the inner workings of the YouTube algorithm that's responsible for determining success on the platform, and how creators can use it to their advantage.Full of actionable advice and concrete strategies, this book teaches readers how to:Launch a channel Create life-changing content Drive rapid view and subscriber growth Build a brand and increase engagement Improve searchability Monetize content and audience Replete with case studies and information from successful YouTube creators, The YouTube Formula is perfect for any creator, entrepreneur, social media strategist, and brand manager who hopes to see real commercial results from their work on the platform.

    James Hirsch’s myth-shattering blend of history, reportage, advocacy, and memoir will speak for, and to, the 20 million Americans who live with this disease. Cheating Destiny offers revealing views of the diabetic subculture, the urge toward secrecy that many diabetics feel, the glycemic rollercoaster they ride constantly, and the remarkable perseverance—even heroism—required for survival.Hirsch is uniquely qualified to write this book. An award-winning journalist and best-selling author, he has lived with type 1 diabetes for twenty-five years. His brother Irl, also a diabetic, is one of the country’s leading diabetologists. Most poignantly, he knows firsthand the toll diabetes can take on parents: his three-year-old son was diagnosed with the disease while Hirsch was writing this book.Hirsch draws on all this expertise to craft an incisive, surprising portrayal of the fascinating science behind the disease and the skyrocketing impact of diabetes on our economy and society. Most striking is his candid, authoritative writing about the psychological and emotional hurdles that diabetics confront every day. Anyone who lives with diabetes—or loves a diabetic—will find here an empowering voice of empathy.

    Barbara Ravage has fashioned an enlightening, invaluable book.” —Stewart O’Nan, author of The Circus Fire: A True Story of an American TragedyThough each of us is just a spark away from being a burn victim, the public knows little and understands less about the world that patients inhabit. Pulling the curtains back on this private and sterile environment, Burn Unit is a riveting account of the frontline efforts—both modern-day and historical—to save lives devastated by fire. With unflinching urgency, Barbara Ravage follows an extraordinary team of healers at Massachusetts General Hospital, the cradle of modern burn treatment and the site of one of the best burn units in the world. From Boston’s Cocoanut Grove fire of 1942 to the treatment of the victims of the Rhode Island nightclub fire in early 2003, we watch everyday heroes do their incredible but punishing work against the backdrop of history. Both a moving human drama and an engrossing scientific exploration of this little-known field of medicine, Burn Unit is an unforgettably powerful read.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    Our looks, longevity, as well as our physical and mental conditions result from the way we eat, breathe, and take care of all our physical and psychological needs. The question is not limited to nutrition only, as is the case of dieting programs.

    In Coming Apocalypse he explains how and why the 'crisis' developed and explains the sort of future we can expect now that lockdowns have destroyed the global economy and changed our way of life. Our world will never be as it was in January 2020. Dr Coleman explains what he believes we can expect.