Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    It provides students who lack a strong science background the ideal balance of reliable nutrition information and practical consumer-oriented knowledge.

    This guidebook is not meant to replace a Lonely Planet/Frommers/Rough Guide, but rather to compliment them. In NZ Frenzy you'll find info about all the South's must-see spots, plus detailed info about the lesser-known and unheralded off-the-beaten-path wonder spots. This guidebook goes WAY beyond the vague outdoor info in the mainstream travel guidebooks. NZ Frenzy is about giving you the details you'll need to find the "real" NZ, the one without lines of tour buses, the one without brochures of pay-to-see commercialized natural "attractions". NZ Frenzy, unlike any of the other mainstream guidebooks, will deliver you to the New Zealand that you've been planning for and fantasizing about. I guarantee it. Please read the reviews of NZ Frenzy North Island to see what travelers think of my info. Are you going to NZ to be a tourist at touristy crowded places or do you want to find the "Real" New Zealand that you'll tell stories about?? When you have an NZ Frenzy in hand, you'll leave the other guidebooks in the glove box and you'll leave the tourists behind!! The South Island has natural wonders beyond compare, but the mainstream media only promotes the commercialized stuff. Don't waste your precious time while in NZ waiting in line at the tourist visitor centers...get NZ Frenzy and go experience the Real New Zealand, the Fabled New Zealand. You can have the trip of a lifetime, you will have the trip of a lifetime!!

    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..

    The Wright Brothers is an historical narrative that draws on extensive archival materials, personal journals, and public records to tell the story of the Wright brothers as men of incredible character and determination along the road towards their significant contributions to aviation history. The summary parallels the structure of the book which is divided into three parts. The first part explores the period of the boys’ childhood through their work on flight testing various models of gliders. The second part picks up with the addition of the engine to the Wright planes and traces the brother’s work through the early stages of powered flight, roughly 1903 to 1908. Part three follows the brothers, now globally famous, through the years when they captured the most attention for their accomplishments. A central aspect of this historical account is the development of Orville and Wilbur Wright as individuals who showed fierce determination in the face of relentless setbacks. It also sheds light on their private nature and their deep bond as brothers. McCullough is a two time winner of the Pulitzer Prize for other historical works, Truman and John Adams. He also won the National Book Award twice and is a recipient of the Presidential Medal of Freedom. His educational background includes a degree in English Literature from Yale University. He is also a well-known narrator, as well as previous host of American Experience. Read more....

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    

    It's for the woman who doesn't want to trade in her champagne for skinny jeans. It's for the woman who is done with dieting, and ready to start paying attention to her health before that number on the scale. It's for the woman who is ready to stop letting her weight define her, and is ready to understand why it always did. This is not a diet book. This is a lifestyle guide. This book will change the way you view your weight and yourself forever. You will walk away feeling empowered, inspired, and downright sexy (and probably craving a glass of bubbly). You will learn how to celebrate yourself and your body. You will learn to make your health a priority, always. And most importantly – you will learn to love yourself, exactly as you are. So get ready to embark on a complete dieting and lifestyle overhaul, sister. You are now on The Champagne Diet! "The Champagne Diet will resonate with every woman with it’s realistic and simple approach to dieting. Alwill delivers a personal, relatable, and funny guide to shedding pounds without deprivation." - Kim Barnouin Co-Author, Skinny Bitch

    Featuring a wide array of distinguished voices, including Peter Kramer, Kay Redfield Jamison, Robert Coles, Lauren Slater, Sandeep Jauhar, and Perri Klass, these original stories create a vivid mural of the medical world and provide invaluable insight for both doctors in training and longtime physicians. Becoming a Doctor portrays the broad arc of a doctor’s life, from a medical student’s uneasy first encounter with a cadaver and her realization that the experience’s redemption will lie ahead in the lives saved, to a resident’s reliance on dance during her grueling year in an inner-city hospital, and a veteran doctor’s profound ruminations on what it means to really listen to a patient’s story.

    Too bad. Because medicine isn't an industry, it's practically witchcraft. Despite the growth of big pharma, HMOs, and hospital chains, medicine remains the isolated work of individual doctors—and the system is going broke fast.So why is Andy Kessler—the man who told you outrageous stories of Wall Street analysts gone bad in Wall Street Meat and tales from inside a hedge fund in Running Money—poking around medicine for the next big wave of technology?It's because he smells change coming. Heart attacks, strokes, and cancer are a huge chunk of medical spending, yet there's surprisingly little effort to detect disease before it's life threatening. How lame is that—especially since the technology exists today to create computer-generated maps of your heart and colon?Because it's too expensive—for now. But Silicon Valley has turned computing, telecom, finance, music, and media upside down by taking expensive new technologies and making them ridiculously cheap. So why not the $1.8 trillion health care business, where the easiest way to save money is to stop folks from getting sick in the first place?Join Kessler's bizarre search for the next big breakthrough as he tries to keep from passing out while following cardiologists around, cracks jokes while reading mammograms, and watches twitching mice get injected with radioactive probes. Looking for a breakthrough, Kessler even selflessly pokes, scans, and prods himself.CT scans of your heart will identify problems before you have a heart attack or stroke; a nanochip will search your blood for cancer cells--five years before they grow uncontrollably and kill you; and baby boomers can breathe a little easier because it's all starting to happen now.Your doctor can't be certain what's going on inside your body, but technology will. Embedding the knowledge of doctors in silicon will bring a breakout technology to health care, and we will soon see an end of medicine as we know it.

    This is the memoir of Joan, who started nursing in the 1940s and whose experiences took her into the Yorkshire mining pits and through the tumult of the 1984-85 miners’ strike.Joan Hart always knew what she wanted to do with her life. Born in South Yorkshire in 1932, she started her nursing training when she was 16, the youngest age girls could do so at the time. She continued working after she married and her work took her to London and Doncaster, caring for children and miners.When she took a job as a pit nurse in Doncaster in 1974, she found that in order to be accepted by the men under her care, she would have to become one of them. Most of the time rejecting a traditional nurse’s uniform and donning a baggy miner’s suit, pit boots, a hardhat and a headlamp, Joan resolved always to go down to injured miners and bring them out of the pit herself.Over 15 years Joan grew to know the miners not only as a nurse, but as a confidante and friend. She tended to injured miners underground, rescued men trapped in the pits, and provided support for them and their families during the bitter miners’ strike which stretched from March 1984 to 1985.Moving and uplifting, this is a story of one woman’s life, marriage and work; it is guaranteed to make readers laugh, cry, and smile.

    From humorous fishing excursions and frightening bear encounters to snow blinding blizzards and quirky characters, they come face to face with the unpredictable Mother Nature and learn the value of friendship, survival, and solitude in a picturesque but harsh life by the sea. Packed with adventures, challenges, and true Alaskan lifestyle.

    The See and Say pronunciation system makes pronouncing unfamiliar terms easy. Because word parts are integral to learning medical terminology, mastery of these "building blocks" is emphasized in every chapter. Organized by body system, chapters begin with an overview of the structures and functions of that system so you can relate these to the specialists, pathology, diagnostic, and treatment procedures that follow. Learning Exercises in each chapter offer a variety of formats that require written answers. Writing terms reinforces learning and provides practice to help master spelling and enhance comprehension.