Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.

    William Herring, MD, a skilled radiology teacher, masterfully covers everything you need to know to effectively interpret medical images. Learn the latest on ultrasound, MRI, CT, and more, in a time-friendly format with brief, bulleted text and abundant high-quality images. Then ensure your mastery of the material with additional online content, bonus images, and self-assessment exercises at www.studentconsult.com.

    Book by Weinberg, Robert A.

    In addition to offering traditional methods for assessing and grading skeletal muscle function, the book provides a comprehensive section on muscle anatomy and innervations that rounds out the testing chapters by linking muscle topography and function. This edition includes a new DVD of tests and procedures video clips that supplement the tests explained in the book.

    In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design.  Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas.

    Featuring a wide array of distinguished voices, including Peter Kramer, Kay Redfield Jamison, Robert Coles, Lauren Slater, Sandeep Jauhar, and Perri Klass, these original stories create a vivid mural of the medical world and provide invaluable insight for both doctors in training and longtime physicians. Becoming a Doctor portrays the broad arc of a doctor’s life, from a medical student’s uneasy first encounter with a cadaver and her realization that the experience’s redemption will lie ahead in the lives saved, to a resident’s reliance on dance during her grueling year in an inner-city hospital, and a veteran doctor’s profound ruminations on what it means to really listen to a patient’s story.

    With the authority of a scholar and the sparkle of an old-time storyteller, Dr. Volney Steele takes the reader from rotgut whiskey to modern anesthetics, from castor oil to antibiotics, and from barroom surgery to modern hospital operations. Dr. Steele wrote Bleed, Blister, and Purge "to shed light on and celebrate the dedication and humanitarianism of those many physicians, nurses, shamans, and people of sound practical sense who saw their patients--often friends and family--through the adversities that bedeviled them."

    Some chapters have been rewritten, making topics such as conjugation and nucleophilic substitution more accessible. Problems are provided which challenge the readers' understanding. read.

    Paul A. Ruggieri has seen the good, the bad, and the ugly of his profession. In Confessions of a Surgeon, he pushes open the doors of the O.R. and reveals the inscrutable place where lives are improved, saved, and sometimes lost. He shares the successes, failures, remarkable advances, and camaraderie that make it exciting. He uncovers the truth about the abusive, exhaustive training and the arduous devotion of his old-school education. He explores the twenty-four-hour challenges that come from patients and their loved ones; the ethics of saving the lives of repugnant criminals; the hot-button issues of healthcare, lawsuits, and reimbursements; and the true cost of running a private practice. And he explains the influence of the white coat code of silence and why patients may never know what really transpires during surgery. Ultimately, Dr. Ruggieri lays bare an occupation that to most is as mysterious and unfamiliar as it is misunderstood. His account is passionate, illuminating, and often shocking-an eye-opening, never- before-seen look at real life, and death, in the O.R.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Gerber, bestselling author of The E-Myth Revisited shares his powerful insights to lead independent physicians to successful practices and enriched lives.Michael Gerber has dedicated much of his professional life to the study of entrepreneurship and business dynamics. His E-Myth Academy is renown in the entrepreneurial world for its business insight and guidance as well as its inspirational advice.In the E-Myth Physician, bestselling author Gerber returns to his roots in order to provide indispensable advice to doctors who own and run their own practices. Gerber provides excellent business insights into topics such as streamlining systems, effective small-business management practices, healthy patient relations and managing cash flow, all with the goal of freeing physicians from the daily grind of running a business and leading them to a happier and more productive life while doing the job they love - practising medicine.

    It is also no secret that these nineteenth-century gynecologists performed experimental caesarean sections, ovariotomies, and obstetric fistula repairs primarily on poor and powerless women. Medical Bondage breaks new ground by exploring how and why physicians denied these women their full humanity yet valued them as "medical superbodies" highly suited for medical experimentation.In Medical Bondage, Cooper Owens examines a wide range of scientific literature and less formal communications in which gynecologists created and disseminated medical fictions about their patients, such as their belief that black enslaved women could withstand pain better than white "ladies." Even as they were advancing medicine, these doctors were legitimizing, for decades to come, groundless theories related to whiteness and blackness, men and women, and the inferiority of other races or nationalities. Medical Bondage moves between southern plantations and northern urban centers to reveal how nineteenth-century American ideas about race, health, and status influenced doctor-patient relationships in sites of healing like slave cabins, medical colleges, and hospitals. It also retells the story of black enslaved women and of Irish immigrant women from the perspective of these exploited groups and thus restores for us a picture of their lives.

    It presents positioning and projection information in an easy-to-read, bulleted format on one side of the page spread, with corresponding positioning photos, radiographic images and anatomical drawings on the other side. Expert content covers pathology, geriatric and pediatric patient populations, survey information, and 100 new positioning photographs for the latest in radiographic positioning. The 6th edition contains a new chapter on digital imaging, and digital imaging information is incorporated where appropriate throughout the book. New photographs and redrawn illustrations create a consistent, visual appearance throughout the book.- Characterized by a clear, easy-to-follow organization that features one projection per page. Positioning and projection information is presented in an easy-to-read bulleted format on the left side of the page, and positioning photos, radiographic images and anatomical drawings are aligned on the right. This show and tell style helps students visualize anatomy and understand positioning.- Includes about 200 of the most commonly requested projections. Competency in performing these projections is necessary for all entry-level practitioners. By contrast, Merrill's Atlas includes over 400 projections and much more information on advanced imaging.- Critique Radiographs provide the basis of classroom or lab discussion. The WB/LM contains questions specific to these radiographs.- Pathologic Indications in appropriate chapters - Introducing pathology with positioning helps students understand the whole patient and improves their ability to produce radiographs that make diagnosis easy for the physician.- Pediatric Applications in appropriate chapters prepare technologists to deal competently with the special needs of their pediatric patients.- Geriatric Applications in appropriate chapters - Important information for technologists to understand the varying needs of their patient base.- Alternative Modalities or procedures inform students of which projections can better demonstrate certain anatomical parts or pathology, or which may be necessary if patient is unable to cooperate fully.- Radiographic Criteria on positioning pages help students develop a routine for evaluating radiographic quality.- Pathology Demonstrated provides students with a larger frame of reference, and therefore a greater understanding, of each projectionA new chapter on digital imaging discusses basic principles, applications, and image quality - digital imaging information essential for making appropriate positioning adjustments - to ensure readers are prepared to encounter new technology in clinical practice.Content updates include a totally new section on surgical radiography, new sections in all chapters on digital imaging considerations, an expanded section on bone densitometry, and a new introduction to positron emission tomography (PET).Updated and revised chapters cover angiography and interventional procedures, and computed tomography.More than 150 new positioning photos, in addition to many updated images, complement the new material.

    Fully revised and featuring lots of new material, this fourth edition provides an unparalleled introduction to 2,000 years of Christian thought. A fully revised new edition of the bestselling introductory textbook in Christian theologyFeatures new sections on monastic schools of theology, the English Reformation, and Radical OrthodoxyIncludes increased discussion of women in the early Church, feminist theology, Eastern Orthodox theology and history, and Catholic teachings on the Doctrine of the ChurchIncorporates user-friendly key terms sections, and study questionsSupported by a website at www.blackwellpublishing.com/mcgrath, containing additional lecturer resources.