Paxil. Zoloft. Turn on your television and you are likely to see a commercial for one of the many selective serotonin reuptake inhibitors (SSRIs) on the market. We hear a lot about them, but do we really understand how these drugs work and what risks are involved for anyone who uses them?Let Them Eat Prozac explores the history of SSRIs from their early development to their latest marketing campaigns and the controversies that surround them. Initially, they seemed like wonder drugs for those with mild to moderate depression patients take just one daily dose, and unlike the tranquilizers that were popular in the 1960s, they supposedly did not lead to addiction. When Prozac was released in the late 1980s, David Healy was among the psychiatrists who prescribed it. But he soon observed that some of these patients became agitated and even attempted suicide. Studies were soon published, citing numerous cases in which patients became anxious and reported increased suicidal thoughts while taking Prozac. Could the new wonder drug actually be making patients worse?Healy draws on his own research and expertise to demonstrate the potential hazards associated with these drugs. He intersperses case histories with insider accounts of the research leading to the development and approval of SSRIs as a treatment for depression. Let Them Eat Prozac clearly demonstrates that the problems go much deeper than a disturbing side-effect of a particular drug. Current FDA regulations encourage drug companies to patent a specific compound and market it effectively to a large population on the basis of minimal effectiveness in a handful of trials.The pharmaceutical industry would like us to believe that SSRIs can safely treat depression, anxiety, and a host of other mental problems. But as Let Them Eat Prozac reveals, this "cure" may be worse than the disease.

    Traces the transformation in vocation and lifestyle in America during the twentieth century throught the experiences of a very diverse group of elderly men and women.

    And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

    

    His family broke down the door to find him unconscious on the floor. None of their lives were ever the same again. Christopher was diagnosed with epilepsy.A Smell of Burning tells the remarkable story of this strange and misunderstood disorder. How certain people, at a particular moment in their life, start to suffer seizures, often preceded by an aura, of which a smell of burning is one of the most common.For many years epilepsy was associated with mental illness or even possession by devils. People with epilepsy were forbidden to marry or have children. Many became victims of Nazi eugenics programmes. To this day many people with epilepsy – sixty million worldwide – still live in fear of exposure.Grant’s book traces the history of the condition and the pioneering doctors whose extraordinary breakthroughs finally helped gain an understanding of how the brain works. He tells the stories of famous people with epilepsy like Julius Caesar, Joan of Arc, Fyodor Dostoevsky and Vincent Van Gogh, and through the tragic tale of his brother, he considers the effect of epilepsy on his own life.

    Leonard G. Horowitz's national best-seller (that the New York Times refused to review) provides the first in-depth exploration into the origins of HIV and Ebola."Health professionals and those involved in infectious disease research will find Emerging Viruses startling: Harvard researcher Horowitz's studies gather evidence to conclude that AIDS and the Ebola viruses evolved during cancer virus experiments in which monkeys were infected with viral genes from other animals. Certain to spark controversy, this provides quite a different view of virus mutations and evolution." -- Midwest Book ReviewContents:The purpose of this bookAbbreviationsProloguePart I. Introduction and scientific background. * Chap. 1. The World Health Organization theory of AIDS * Chap. 2. WHO plays in the big leagues * Chap. 3. Cold war, biological weapons, and world health * Chap. 4. The road to Fort Detrick runs through Bethesda * Chap. 5. The emperor's new virus * Chap. 6. Gallo's research anthology: the AIDS buck and virus stops here * Chap. 7. An interview with Dr. Robert Strecker * Chap. 8. HIV-1, 2 and the big bangPart II. The political terrain. * Chap. 9. Early targeting of minority America * Chap. 10. African foreign policy and population control * Chap. 11. Henry Kissinger's new world order * Chap. 12. Silent coup in American intelligence * Chap. 13. USAID and New York blood * Chap. 14. Central West African vaccine trialsPart III. Covert operations. * Chap. 15. The CIA/Detrick operation * Chap. 16. Project MKNAOMI * Chap. 17. The CIA's human experiments * Chap. 18. Nazi roots of American Central Intelligence: the biological warfare industry * Chap. 19. The CIA in Africa * Chap. 20. ORTRAG: links to Nazis, NATO, NASA, the NCI and AIDS * Chap. 21. Marburg, Ebola and chilling propaganda in The Hot Zone * Chap. 22. The special virus cancer program * Chap. 23. The man-made origin of Marburg and Ebola * Chap. 24. Icing on the cake and conclusionsReferences and notesIndexAbout the author..

    Soon after the World Trade Center towers fell, leaving ashes floating over journalist Lee Smith’s Brooklyn neighborhood, he left for Cairo to find out “why the Arabs hate us.” He spent eight years reporting from Cairo, Beirut, and Jerusalem and discovered that the anger and disorder in the Middle East are not caused by a clash of civilizations between East and West, as is so often contended. Instead, he found a clash among Arab civilizations that led him to reassess America’s efforts to bring a “freedom agenda” to the Arab world. In The Strong Horse, Lee Smith offers paradigm-shifting insight into how the Arab world works and what America’s role should be in that world today.The Strong Horse combines evocative reporting with brilliant analysis that gracefully overturns many of the myths held about the region. Perhaps the most important myth that hobbles policy in the Middle East is the idea that the turmoil there is the legacy of Western interference. In fact, Smith shows, violence has been the only currency of power in the region for centuries. Another myth is that dictators are the main cause of widespread oppression in countries like Egypt, Saudi Arabia, and Syria. Yet Smith finds that much of the repression that stagnates Arab society happens at the level of the family where rigorous redlines of social and religious behavior are enforced. What’s more, in a region seething with minorities, with no liberal tradition, no reverence for individual rights, and no tolerance for difference, authoritarian regimes exist because the alternative, as has been seen most recently in Lebanon and Iraq, is endless sectarian violence. In The Strong Horse, Smith reveals the Arab world to be defined by a tribal culture where support goes to “the strong horse.” Technology and democracy will not transform the Arab world, Smith convincingly demonstrates. Rather, Arab peoples and governments naturally align themselves with the strongest power, even when that power is the United States or Israel. Smith’s groundbreaking book redefines America’s role in the Middle East as “benevolent strong horse” and offers an important corrective to our understanding of the Arab world.

    Then a new movement-mystical, materialistic, and virulently anti-Christian-began to spread among them like wildfire. The foreigners laughed at the peasants' martial-arts routines and nicknamed them "the Boxers"-never imagining that the group, with the backing of China's empress dowager, would soon terrorize the world...This acclaimed account of the Boxer Rebellion, by an Oxford-trained historian, is an important new addition to every shelf of high-quality, highly accessible history.

    Webb. The Man Who Ran the Moon explores a time when Webb and an elite group of charismatic business associates took control of America's Apollo moon project, sometimes with disturbing results. In 1967, NASA was rocked by disaster and Apollo was grounded. Webb was savaged in a Congressional investigation. Not just a matter of broken hardware, there were accusations of corruption at the heart of America's space effort. Some of Webb's political allies had been caught up in the biggest scandal ever to hit Washington prior to Watergate. The backwash unfairly tainted NASA's chief. By the time of the first triumphant lunar landing, Webb had resigned and his name had all but been forgotten. But he's the man who got us to the moon, and the power base he forged in the 1960s has kept NASA on a solid footing to this day. Washington insiders now acknowledge Webb as one of the greatest leaders in modern American history. No space boss since his time has wielded so much power and such a powerful story.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied. Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself. Elderhood is for anyone who is, in the author's own words, "an aging, i.e., still-breathing human being."

    Thompson and P. J. O’Rourke so much fun” (The Washington Post). Bringing together Taibbi’s most incisive and hilarious work from his “Road Work” column in Rolling Stone, Smells Like Dead Elephants shines an unflinching spotlight on the corruption, dishonesty, and sheer laziness of our leaders. Taibbi has plenty to say about George W. Bush, Jack Abramoff, Tom DeLay, and all the rest, but he doesn’t just hit inside the Beltway. He gets involved in the action, infiltrating Senator Conrad Burns’s birthday party under disguise as a lobbyist for a fictional oil firm that wants to drill in the Grand Canyon. He floats into apocalyptic post-Katrina New Orleans in a dinghy with Sean Penn. He goes to Iraq as an embedded reporter, where he witnesses the mind-boggling dysfunction of our occupation and spends three nights in Abu Ghraib prison. And he reports from two of the most bizarre and telling trials in recent memory: California v. Michael Jackson and the evolution-vs.-intelligent-design trial in Harrisburg, Pennsylvania. Equally funny and shocking, this is excellent work from one of our most entertaining writers.

    Reay Tannahill's scholarly, yet accessible study ranges from the earliest form of contraception (one Egyptian concoction included crocodile dung) to some latter- day misconceptions about it- like the men who joined their lovers in taking the pill 'just to be on the safe side.' It surveys all manner of sexual practice, preference and position (the acrobatic 'wheelbarrow' position, the strenuous 'hovering butterflies' position...) and draws on souces as diverse as THE ADMIRABLE DISCOURSES OF THE PLAIN GIRL, the EXHIBTION OF FEMALE FLAGELLANTS, IMPORTANT MATTERS OF THE JADE CHAMBER and THE ROMANCE OF CHASTISEMENT. Whether writing on androgyny, courtly love, flagellation or zoophilia, Turkish eunuch's Greek dildoes, Taoist sex manuals or Japanses geisha girls, Reay Tannahill is consistently enlightening and entertaining.

    In Germs, three veteran reporters draw on top sources inside and outside the U.S. government to lay bare Washington's secret strategies for combating this deadly threat.Featuring an inside look at how germ warfare has been waged throughout history and what form its future might take (and in whose hands), Germs reads like a gripping detective story told by fascinating key figures: American and Soviet medical specialists who once made germ weapons but now fight their spread, FBI agents who track Islamic radicals, the Iraqis who built Saddam Hussein's secret arsenal, spies who travel the world collecting lethal microbes, and scientists who see ominous developments on the horizon. With clear scientific explanations and harrowing insights, Germs is a masterfully written—and timely—work of investigative journalism.

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?