We've all done them. Whether it's a cup of coffee or a glass of wine, a cigarette or a sleeping pill. But how well do we understand the effects of the drugs we take - legal or illegal?Say Why to Drugs investigates the science behind recreational drugs- debunking common myths and misconceptions, as well as containing the most recent scientific research. Looking at a range of drugs, this book provides a clear understanding of how drugs work and what they're really doing to your mind and body. Along the way you will find out why ketamine is on the WHO's list of essential medicines, why some researchers hope MDMA could treat PTSD, and much more.Enlightening, entertaining, and thought-provoking, Say Why to Drugs is a compelling read that will surprise and educate proponents on both sides of the drugs debate.

    As he bent down to pick up his golf ball, something strange and massive happened inside his head; part of his brain seemed to unhinge, to split apart and float away. For an utterly inexplicable reason, a tiny blood vessel, thin as a thread, deep inside the folds of his gray matter had suddenly shifted ever so slightly, rubbing up against his acoustic nerve. Any noise now caused him excruciating pain. After months of seeking treatment to no avail, in desperation Sarkin resorted to radical deep-brain surgery, which seemed to go well until during recovery his brain began to bleed and he suffered a major stroke. When he awoke, he was a different man. Before the stroke, he was a calm, disciplined chiropractor, a happily married husband and father of a newborn son. Now he was transformed into a volatile and wildly exuberant obsessive, seized by a manic desire to create art, devoting virtually all his waking hours to furiously drawing, painting, and writing poems and letters to himself, strangely detached from his wife and child, and unable to return to his normal working life. His sense of self had been shattered, his intellect intact but his way of being drastically altered. His art became a relentless quest for the right words and pictures to unlock the secrets of how to live this strange new life. And what was even stranger was that he remembered his former self. In a beautifully crafted narrative, award-winning journalist and Pulitzer Prize finalist Amy Ellis Nutt interweaves Sarkin’s remarkable story with a fascinating tour of the history of and latest findings in neuroscience and evolution that illuminate how the brain produces, from its web of billions of neurons and chaos of liquid electrical pulses, the richness of human experience that makes us who we are. Nutt brings vividly to life pivotal moments of discovery in neuroscience, from the shocking “rebirth” of a young girl hanged in 1650 to the first autopsy of an autistic savant’s brain, and the extraordinary true stories of people whose personalities and cognitive abilities were dramatically altered by brain trauma, often in shocking ways. Probing recent revelations about the workings of creativity in the brain and the role of art in the evolution of human intelligence, she reveals how Jon Sarkin’s obsessive need to create mirrors the earliest function of art in the brain. Introducing major findings about how our sense of self transcends the bounds of our own bodies, she explores how it is that the brain generates an individual “self” and how, if damage to our brains can so alter who we are, we can nonetheless be said to have a soul. For Jon Sarkin, with his personality and sense of self permanently altered, making art became his bridge back to life, a means of reassembling from the shards of his former self a new man who could rejoin his family and fashion a viable life. He is now an acclaimed artist who exhibits at some of the country’s most prestigious venues, as well as a devoted husband to his wife, Kim, and father to their three children. At once wrenching and inspiring, this is a story of the remarkable human capacity to overcome the most daunting obstacles and of the extraordinary workings of the human mind.

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Cutting edge research in neuroscience suggests you can. In The Mindfulness Edge, you'll discover how a subtle inner shift, called mindfulness, can transform things that you already do every day into opportunities to become a better leader. This book brings together training programs presented to Fortune 500 companies, universities, and other organizations around the world to present a complete, self-guided process that enables you to systematically train to improve self-awareness and mental agility. Step-by-step guidance for applying mindfulness to break free from conditioned ways of behaving and making decisions gives you the keys to both better business acumen and emotional and social intelligence, which allows you to create and sustain high-performance team cultures. You’ll learn how to quickly and seamlessly integrate mindfulness training into your daily life and easy-to-understand insight into the neuroscience behind it. Every chapter includes review questions to reinforce covered material and accelerate progress toward mastering the most important element of professional and personal success: your mind. In this book, you'll learn how mindfulness training helps you:- Quickly improve business acumen and your impact on the bottom line- Become more innovative and attract/retain innovative team members- Develop the emotional intelligence essential for creating and sustaining a winning culture- Realize the extraordinary leadership presence that inspires greatness in others- Realize happiness during even the most simple, mundane moments of your dayWhether you’re brushing your teeth, waiting for the train, or walking to the office, The Mindfulness Edge will help you take advantage of each moment to gain a significant competitive edge and more fully enjoy your life.

    No new cells. No major changes. If you grew up depressed, angry, sad, aggressive, or nasty, you'd be that way for life. And, as you grew older, there'd be nowhere to go but down, as disease, age, or injury wiped out precious, irreplaceable brain cells. But over the past five, ten, twenty years, all that's changed. Using fMRI and PET scanning technology, neuroscientists can now look deep inside the human brain and they've discovered that it's amazingly flexible, resilient, and plastic. Pictures of the Mind: What the New Neuroscience Tells Us About Who We Are shows you what they've discovered and what it means to all of us. Through author Miriam Boleyn-Fitzgerald's masterfully written narrative and use stunning imagery, you'll watch human brains healing, growing, and adapting to challenges. You'll gain powerful new insights into the interplay between environment and genetics, begin understanding how people can influence their own intellectual abilities and emotional makeup, and understand the latest stunning discoveries about coma and "locked-in" syndrome. You'll learn about the tantalizing discoveries that may lead to cures for traumatic brain injury, stroke, emotional disorders, PTSD, drug addiction, chronic pain, maybe even Alzheimer's. Boleyn-Fitzgerald shows how these discoveries are transforming our very understanding of the "self," from an essentially static entity to one that can learn and change throughout life and even master the art of happiness.

    Jack Kruse gives us his first book, Epi-paleo Rx: The Prescription for Disease Reversal and Optimal Health. Kruse, who used his findings to lose 140 pounds and pack on muscle, takes the reader through his prescriptions for obesity, diabetes, heart disease, osteoporosis, autoimmunity, brain health, and aging. The material weaves together surprises from our Ice Age origins with the new science of epigenetics, or the effect of diet and environment on gene expression.A champion of “biohacking,” the art of tinkering with one’s own biology, Kruse pounces on his own profession’s ineptness when it comes to chronic conditions and urges readers to take health care into their own hands. He discusses which labs to order and why, why your doctor is obligated to write you a prescription you don’t need, the vital roles daylight and darkness play in metabolism, and the optimal diet for different stages of health and different times of year. Perhaps Kruse’s more fascinating contributions to Paleo literature are his findings on cold therapy—the effect of cold environments, immersion in cold water, and ice pack therapy on disease reversal, pain, and optimal living. Kruse explains how our origins as cold-adapted mammals hold the key to disease reversal, using a shocking biohack to prove his theory.The Epi-paleo Rx is the result of Kruse’s abundant research and clinical application in his practice as a neurosurgeon. Kruse questions conventional wisdom about human metabolism and chronic disease, arguing science has incomplete information when it comes to insulin resistance, diabetes, obesity, and their related illnesses. By examining the human body through the prism of our early beginnings and the science of epigenetics, we find each of us already possesses the “owner’s manual” to reverse disease and live optimally.

    The ability to put ourselves in somebody else's shoes, to see the world through somebody else's eyes . . .' Barack ObamaEmpathy is the power of understanding others, imaginatively entering into their feelings. It is a fundamental human attribute, without which mutually co-operative societies cannot function. In a revolutionary development, we now know who has it, who lacks it and why. Via the MRI scanner we are mapping the human brain. This is a new frontier that reveals a host of beneficial ideas for childcare, teens challenged by the internet, the justice system, decent healthcare, tackling racism and resolving conflicts. In this wide-ranging and accessible book full of entertaining stories that are underlined by the latest scientific research, Peter Bazalgette also mounts a passionate defence of arts and popular culture as a means of bridging the empathy gap. As the world's population expands, consuming the planet's finite resources, as people haunted by poverty and war are on the move and as digital communications infinitely complicate our social interactions, we find our patience and our sympathy constantly challenged. Here is the antidote.Culminating in a passionate manifesto on empathy, The Empathy Instinct is what makes us human and what can make us better humans.

    As a result, many stroke survivors are treated with outdated or ineffective therapies. Stronger After Stroke puts the power of recovery in the reader’s hands by providing easy instructions for reaching the highest possible level of healing. Written for stroke survivors, their caregivers, and their loved ones, the book presents a new approach that is startling in its simplicity: stroke survivors recover by using the same learning techniques that anyone uses to master anything. Basic concepts are covered, including repetition of task-specific movements, proper scheduling of practice, challenges at each stage of recovery, and setting goals and recognizing achievements. Stronger After Stroke bridges the gap between stroke survivors and what they desperately need: easily understandable and scientifically accurate information on how to achieve optimal rehabilitation.

    But how the mind works remains one of humankind's greatest mysteries. With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think? Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world—to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure. Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.

    He finds that nothing can capture a person’s attention as strongly as mystery, and that mystery is the key principle in how humans view and understand the world. Whenever patterns are broken, we are hard-wired to find out why. Without our curiosity driving us to pursue new discoveries and solve stubborn problems, we would never have achieved the breakthroughs that have revolutionized human medicine, technology—and culture. From Shakespeare’s plays to the earliest works of the detective genre, our entertainment and media have continually reinvented successful forms of mystery to hook audiences. Here, Lehrer interviews individuals in unconventional fields—from dedicated small-business owners to innovative schoolteachers—who use mystery to challenge themselves and to motivate others to reach to new heights. He also examines the indelible role of mystery in our culture, revealing how the magical world of Harry Potter triggers the magic of dopamine in our brains, why the baseball season is ten times longer than the football season, and when the suspect is introduced in each episode of Law & Order. Fascinating, illuminating, and fun, Mystery explores the many surprising ways in which embracing a sense of awe and curiosity can enrich our lives.

    Your level of vitality is directly connected to your brain. When your brain thrives, growing and making new connections, you are invigorated, infused with a new sense of aliveness and possibility, capable of infinitely new ways of moving, thinking, and feeling. Combining cutting-edge neuroscience, the work of Dr. Moshe Feldenkrais, and her own method based on more than thirty years of experience working with thousands of people around the world, Anat Baniel has defined the Nine Essentials your brain needs to flourish. In this breakthrough book, she offers specific, practical advice for incorporating those Essentials into everything you do to achieve immediate and powerful benefits.In Move Into Life, you’ll:•Learn the Nine Essentials your brain requires to thrive, including movement with attention, subtlety, and variation•Experience simple, safe physical and mental exercises that satisfy those needs and thus awaken your vitality •Discover why and how these methods work• Find easy ways of incorporating the Essentials into your daily life so every activity–from washing the dishes to working at your desk, from interacting with your loved ones to your golf game–brings you renewed vitalityEndorsed by leading physicians, scientists, and transformational teachers, the Anat Baniel Method will help you enjoy renewed energy and stamina. You’ll be lighter on your feet. Your memory will be better. Thinking and problem solving will become easier. If you are active in a sport, yoga, or work out at the gym, you will notice yourself performing better and with greater ease and fewer injuries. Most important, you will experience yourself moving more fully into your life.

    Because of that, we can fundamentally change the way our brains work--for the better. Sort Your Brain Out shows you how to re-wire your brain to be more creative, make better decisions, improve your mood and memory, manage stress, and stave off senility. The book explains how the brain works and what you can do every day to subtly alter your behaviours, beliefs, and motivations to create positive change in your life and health.Presents tools and exercises for maximizing your brain power Written by brain scientist and television personality Dr. Jack Lewis and motivational speaker Adrian Webster Includes brain-powered self-help advice that will improve your mood, help you deal with stress, and be better and smarter at work or in your everyday life In Sort Your Brain Out, you'll discover how to shape and control the most adaptable organ in your body to think more creatively, keep your memory sharp, and live a better life on a daily basis.

    Although people with autism live in the same physical world and deal with the same `raw material' their perceptual world turns out strikingly different from that of non-autistic people. It is widely reported that autistic people have `unusual' sensory perceptual experiences that may involve hypo- and hypersensitivity, fluctuation between different `volumes' of perception and difficulty interpreting a sense.In this book, Olga Bogdashina attempts to define the role of sensory perceptual problems in autism identified by autistic individuals themselves. Often ignored by many professionals, this is one of the main problems highlighted by autistic individuals. This book singles out possible patterns of sensory experiences in autism and the cognitive differences caused by them. The final chapters are devoted to assessment and intervention issues with practical recommendations for selecting appropriate methods and techniques to eliminate the problems and enhance the strengths.Sensory Perceptual Issues in Autism and Asperger Syndrome is vital to teachers and other professionals working with autistic individuals to fully comprehend sensory perceptual differences in autism. This book will help readers select appropriate methods for dealing with autistic individuals. In addition, parents of autistic individuals and autistic individual themselves will find the information will enable them to initiate relevant strategies and environmental changes to facilitate more effective learning.

    This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory.The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.

    STILL ALICE An accomplished professor diagnosed with Alzheimer’s disease learns that she is more than what she can remember. Now a major motion picture from Sony Pictures Classics. LEFT NEGLECTED A busy multitasking mother in her thirties learns to pay attention to what matters most in life after a car crash leaves her with a traumatic brain injury and a bizarre neurological condition called Left Neglect.