It provides the background needed to understand related drugs currently on the market, as well as drugs yet to be released. In simplifying a complex subject, this text focuses on the essentials of pharmacology. Large print is used to show need-to-know information, and small print is used for nice to know material. At the end of each chapter, a summary of major nursing implications helps in applying the material to real-world situations. This edition includes a new companion CD-ROM featuring NCLEX(R) examination-style review questions, a variety of electronic calculators, and animations depicting drug mechanisms and effects.Uses a prototype drug approach that places a strong emphasis on understanding over memorization - equipping students with the knowledge to learn not only about related drugs currently on the market, but also about those drugs that will be released once the student begins practice.Summaries of Major Nursing Implications at the end of each chapter provide an in-depth look at assessment, implementation, and ongoing evaluations.Utilizes large print for essential information and small print for nice-to-know information to help both faculty and students focus their limited classroom and study time on understanding the essentials.Concise drug summary tables present detailed information on individual drugs, including class, generic and trade names, dosages, routes, and indications.Key Points at the end of each chapter summarize content in a bulleted format to help students review important concepts.Prototype drug discussions employ a clear and consistent format with separate headings for Mechanism of Action; Pharmacologic Effects; Pharmacokinetics; Therapeutic Uses; Adverse Effects; Drug Interactions; and Preparations, Dosage, and Administration.An attractive full-color design adds visual interest, highlights key information, and facilitates student learning.Drugs for Multiple Sclerosis and Drugs for Hemophilia chapters.Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia chapter covers newsworthy drugs such as Viagra and Levitra.Special Interest Topics boxes on current issues in pharmacology, such as Medication-Overuse Headache: Too Much of a Good Thing and Face Time with Botox.Adult Immunization appendix summarizes the latest information on immunizations.Numerous new illustrations show drug mechanisms and effects, and depict topics such as histologic changes in Alzheimer's disease and the movement of drugs following GI absorption.

    Starting with their roots in the Australian pub circuit, this book takes a thorough look at where the band came from, where they've been, and where they're going. Bon Scott and the Young brothers' earlier bands are discussed, as well as the trio's first collaboration, supplemented by rare photographs and interviews with more than 50 of the band's friends and colleagues. Previously unpublished details on Bon Scott's untimely death in 1980 and the strange circumstances around it are revealed, along with information on AC/DC's upcoming album, their first in five years.

    He's a genuine voice of the people, the bastard child of Woody Guthrie and James Brown, and an elder statesman who has inspired generations of bands. He's won twenty Grammy Awards, an Oscar, two Golden Globes, and is a member of two Halls of Fame.There are dozens of books about Springsteen. What's left to say? Nothing objective, perhaps. But when it comes to music, objectivity is highly overrated. Robert Wiersema has been a Springsteen fan since he was a teenager, following tours to see multiple shows in a row, watching set lists develop in real time via the Internet, ordering bootlegs from shady vendors in Italy. His attachment is deeper than fandom, though: he's grown up with Springsteen's songs as the soundtrack to his life, beginning with his youth in rural British Columbia and continuing on through dreams of escape, falling in love, and becoming a father.Walk Like a Man is the liner notes for a mix tape, a blend of biography, music criticism, and memoir. Like the best mix tapes, it balances joy and sorrow, laughter seasoning the dark-night-of-the-soul questions that haunt us all. Wiersema's book is the story of a man becoming a man (despite getting a little lost along the way), and of Springsteen's songs and life that have accompanied him on his journey.

    Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients, CoQ10, carnitine, ribose, have on the cardiovascular system. Readers will learn how these miraculous nutrients work throughout the body, essentially charging up every body cell to function at optimal capacity.

    It also contains one of the world's largest supplies of natural gas, a resource that has been dismissed as inaccessible until recently. Technological developments that combine horizontal drilling with hydraulic fracturing ("fracking") have removed physical and economic barriers to extracting hundreds of trillions of cubic feet of gas from bedrock deep below the Appalachian basin. Beginning in 2006, the first successful Marcellus gas wells by Range Resources, combined with a spike in the value of natural gas, spurred a modern-day gold rush a "gas rush" with profound ramifications for environmental policy, energy markets, political dynamics, and the lives of the people living in the Marcellus region. Under the Surface is the first book-length journalistic overview of shale gas development and the controversies surrounding it.Control over drilling rights is at stake in the heart of Marcellus country northeast Pennsylvania and central New York. The decisions by landowners to work with or against the companies and the resulting environmental and economic consequences are scrutinized by neighbors faced with similar decisions, by residents of cities whose water supply originates in the exploration area, and by those living across state lines with differing attitudes and policies concerning extraction industries. Wilber's evenhanded treatment gives a voice to all constituencies, including farmers and landowners tempted by the prospects of wealth but wary of the consequences, policymakers struggling with divisive issues, and activists coordinating campaigns based on their respective visions of economic salvation and environmental ruin. Wilber describes a landscape in which the battle over the Marcellus ranges from the very local yard signs proclaiming landowners' allegiances for or against shale gas development to often conflicting municipal, state, and federal legislation intended to accelerate, delay, or discourage exploration.For millions of people with a direct stake in shale gas exploration in the Marcellus or any number of other emerging shale resources in the United States and worldwide, or for those concerned about the global energy outlook, Under the Surface offers a worthwhile and engaging look at the issues.

    Deciding on exactly the right strategy in any particular situation can be very difficult. Perhaps this is why very few authors have attempted to analyze this game even though it is widely played. In 1989, the first edition of this text appeared. Many ideas, which were only known to a small, select group of players, were now made available to anyone who was striving to become an expert, and a major gap in the poker literature was closed. It is now a new century, and the authors have again moved the state of the art forward by adding over 100 pages of new material, including an extensive section on "loose games." Anyone who studies this text, is well disciplined, and gets the proper experience should become a significant winner. Some of the other ideas discussed in this 21st century edition include the cards that are out, the number of players in the pot, ante stealing, playing big pairs, playing little and medium pairs, playing three-flushes, playing three-straights, randomizing your play, fourth street, pairing your door card on fourth street, proper play on fifth, sixth, and seventh streets, defending against a possible ante steal, playing against a paired door card, scare card strategy, and buying a free card.

    Clear, concise language sets the record straight on a diverse range of topics as Lawrence Potter presents answers to fifty-seven questions about the world we live in, stretching from "What is jihad?" to "is fair trade a good thing?" and "Is there still a war in Chechnya?" . Important information including the latest research on environmental issues and the history behind current events worldwide is presented in enough detail to be useful without overwhelming readers with too much making for a balanced, informed reference guide.Also covering... What is the problem with plastic bags? What did Sadaam do to the Kurds? What is the difference between a sunni and a shia and is it possible that global warming is not taking place in a thoroughly updated new edition complete with a new chapter explaining the problem of Afghanistan

    It transcends the years, the standings, and all other distractions. And thanks to the countless remarkable football games between Michigan and Ohio State--and hundreds of thousands of devoted alumni and followers--the rivalry is now an enormous cultural event.

    The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Written with Barnard’s cooperation and with input from dozens of associates, drivers and rivals, this biography tells the entire story, both personal and professional, of a British design genius. Barnard’s technical achievements are explored in detail — and in accessible language — with special emphasis on his brilliant initiatives while at McLaren (the first carbon-fibre composite chassis) and Ferrari (the first semi-automatic gearbox). The Perfect Car is also a human-interest story, telling a tale of innovation under intense pressure while Barnard endeavoured to maintain a stable family life. This is a landmark book that will be relished by anyone interested in motorsport and design.

    

    TheCult of the Luxury Brand illuminates the mysterious inner workings of Asia’s love affair with luxury for business professionals and intrigued consumers alike.

    And, should you ever get to hold one, you will find the human heart to be rubbery and shockingly light.'What Could Possibly Go Wrong? is a report from the front line of emergency medicine, the first ever account of what it is like to work as an air ambulance doctor. Whether describing cutting through a patient's breastbone to plug a stab wound or barrel rolling a light aircraft at 5,000 feet, Tony Bleetman captures the sheer adrenaline of racing through the sky to save lives. You will learn how to land a helicopter on the side of a mountain, what it means to encounter death every day, and how to perform a tracheotomy in real life (clue: it doesn’t involve a ball-point pen).Funny, shocking and moving, What Could Possibly Go Wrong? is a glimpse at a world where the wrong decision can mean the difference between life and death.Originally published as You Can't Park There: The Highs and Lows of an Air Ambulance Doctor.

    By studying the physical astronomy of all the planets in the Solar System, we can attempt to understand their true nature. Ultimately, these lectures will bring us to a greater understanding of the Solar System's creation, which brings us again back to the beginning and what it means to us as we look outward from our rotating Earth.

    The legendary annihilation in 1883 of the volcano-island of Krakatoa — the name has since become a byword for a cataclysmic disaster — was followed by an immense tsunami that killed nearly forty thousand people. Beyond the purely physical horrors of an event that has only very recently been properly understood, the eruption changed the world in more ways than could possibly be imagined. Dust swirled round the planet for years, causing temperatures to plummet and sunsets to turn vivid with lurid and unsettling displays of light. The effects of the immense waves were felt as far away as France. Barometers in Bogotá and Washington, D.C., went haywire. Bodies were washed up in Zanzibar. The sound of the island's destruction was heard in Australia and India and on islands thousands of miles away. Most significant of all — in view of today's new political climate — the eruption helped to trigger in Java a wave of murderous anti-Western militancy among fundamentalist Muslims: one of the first outbreaks of Islamic-inspired killings anywhere. Simon Winchester's long experience in the world wandering as well as his knowledge of history and geology give us an entirely new perspective on this fascinating and iconic event as he brings it telling back to life.