Today, we hear stories of over-worked midwives and short-staffed hospitals, but the truth is that childbirth has never been easier. For our grandmothers, pregnancy was a journey into the unknown. Rather than ponder which pushchair to buy or fret over towelling versus disposable nappies, they worried about what lay ahead. Home births were often lonely affairs with the midwife or doctor only visiting when birth was imminent. During hospital births, medical staff rarely gave explanations and would push and prod with little offer of pain relief let alone sympathy. Standard care in labour was the O.B.E. - Oil, Bath and Enema. Nursing staff gave firm rules on how long to stay in bed, how to lie in bed and even when to go to the toilet. And life didn't get much easier after giving birth. Taking care of a home and baby was hard work when there were few washing machines, no disposable nappies and heating came from coal carried in from the back yard.

    A killer with little respect for class or wealth, cholera ravaged the squalid streets of Soho and rocked the great centers of Victorian power. In this gripping book, Sandra Hempel tells the story of John Snow, a reclusive doctor without money or social position, who—alone and unrecognized—had the genius to look beyond the conventional wisdom of his day and uncover the truth behind the pandemic. She describes how Snow discovered that cholera was spread through drinking water and how this subsequently laid the foundations for the modern, scientific investigation of today's fatal plagues. A dramatic account with a colorful cast of characters, The Strange Case of the Broad Street Pump features diversions into fascinating facets of medical and social history, such as Snow's tending of Queen Victoria in childbirth, Dutch microbiologist Leeuwenhoek's deliberate breeding of lice in his socks, Dickensian children's farms, and riotous nineteenth-century anesthesia parties. An afterword discusses the new threat of infectious diseases—including malaria, yellow fever, and cholera—with today's global warming. Copub: Granta

    The Cell: a Molecular Approach meets this challenge by providing students with not only the current information, but also with an introduction to the experimental nature of contemporary research. Designed for use in introductory cell biology courses, The Cell presents current, comprehensive science in a readable and cohesive text that students can master in the course of one semester. The new third edition of The Cell retains the organization, themes, and special features of earlier editions, but is updated to reflect scientific advances since publication of the second edition, including progress in genome sequencing, advances in understanding transcriptional regulation and mRNA processing, use of DNA microarrays in global studies of gene expression and cancer diagnostics, advances in nuclear transport and protein trafficking, progress in understanding the regulation of programmed cell death, potential medical applications of embryonic cells, and development of oncogene-targeted treatments. Key Experimental boxes in each chapter describe seminal experiments in modern cell biology, showing the detail and background to give students a sense of doing science. Molecular Medicine boxes relate basic science to clinical practice or potential and show the excitement of molecular discovery and solutions to disease. Chapter summaries are organized in outline form corresponding to the major sections and subsections of each chapter. This section-by-section format is coupled with a list of the key terms introduced in eachsection, providing a succinct but comprehensive review of the material. The full-color art program is both pedagogically and scientifically outstanding. In addition, each chapter includes a brief chapter outline, boldfaced key terms (also defined in the glossary), and many new chapter-end questions with answers in the back of the book. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. The book can be bundled for purchase with a special edition of Molecules, Cells, and Genes, a CD-ROM keyed to the textbook and combining the essential features of a Study Guide and Problems book.

    But what if science itself can’t be relied on?Medicine, education, psychology, health, parenting – wherever it really matters, we look to science for advice. Science Fictions reveals the disturbing flaws that undermine our understanding of all of these fields and more.While the scientific method will always be our best and only way of knowing about the world, in reality the current system of funding and publishing science not only fails to safeguard against scientists’ inescapable biases and foibles, it actively encourages them. From widely accepted theories about ‘priming’ and ‘growth mindset’ to claims about genetics, sleep, microbiotics, as well as a host of drugs, allergies and therapies, we can trace the effects of unreliable, overhyped and even fraudulent papers in austerity economics, the anti-vaccination movement and dozens of bestselling books – and occasionally count the cost in human lives.Stuart Ritchie was among the first people to help expose these problems. In this vital investigation, he gathers together the evidence of their full and shocking extent – and how a new reform movement within science is fighting back. Often witty yet deadly serious, Science Fictions is at the vanguard of the insurgency, proposing a host of remedies to save and protect this most valuable of human endeavours from itself.

    Select a topic for entirely strategic reasons. Choose the coolest supervisor. Write only to deadlines. Expect people to hold your hand. Become “that” student. When it comes to a masters or PhD program, most graduate students don’t deliberately set out to  fail. Yet, of the nearly 500,000 people who start a graduate program each year, up to half will never complete their degree. Books abound on acing the admissions process, but there is little on what to do once the acceptance letter arrives. Veteran graduate directors Kevin D. Haggerty and Aaron Doyle have set out to demystify the world of advanced education. Taking a wry, frank approach, they explain the common mistakes that can trip up a new graduate student and lay out practical advice about how to avoid the pitfalls. Along the way they relate stories from their decades of mentorship and even share some slip-ups from their own grad experiences. The litany of foul-ups is organized by theme and covers the grad school experience from beginning to end: selecting the university and program, interacting with advisors and fellow students, balancing personal and scholarly lives, navigating a thesis, and creating a life after academia. Although the tone is engagingly tongue-in-cheek, the lessons are crucial to anyone attending or contemplating grad school. 57 Ways to Screw Up in Grad School allows you to learn from others’ mistakes rather than making them yourself.

    There are classical logic puzzles, lateral thinking puzzles, “who am I?” riddles, mathematical brain teasers, word ladders, ditloids, and a large selection of illustrated pen and paper, coins, cups, and toothpicks puzzles (please view the preview of this book for a full listing). This is the first time a collection of such breadth has been compiled and formatted especially for Kindle devices. The puzzles have been carefully organized into 25 chapters, and each question is hyperlinked to its solution, to provide utmost ease of navigation. Alongside the world’s most famous riddles, are some lesser known gems, and some brand new puzzles, in print here for the first time. Our aim was to create a definitive compendium of riddles and puzzles to bring enjoyment to people of all ages. We hope you will enjoy unraveling them as much as we enjoyed creating and editing them. Here are a handful of sample riddles: Outside the Box Riddles: You need to divide a round birthday cake into eight pieces, so each of your guests will have something to eat. How can you do this by making only three straight cuts with a knife, and without moving any of the pieces? The king’s two bodyguards developed an ingenious method for assuring the king’s safety. With the king standing between them, they would face in opposite directions; one looking to the west and the other to the east, but at the same time, and without the use of any reflective surfaces, they would both be able to observe the king clearly. How was this possible? Pure Logic Riddles: There are two glasses. One contains water, and the other contains an equal quantity of wine. A teaspoon of water is removed and mixed into the glass of wine. A teaspoon of the wine-water mixture is then removed and mixed into the glass of water. Which of the mixtures is now purer? The sorcerer’s tower was enchanted in such a way that it was able to build itself. Bricks, slates, tiles, and panes of glass, all flew to it of their own accord and danced into position. The tower doubled in size every day until after 100 days it reached a height that provided fine views over the entire realm. How many days did the tower take to reach half its full height? Lateral Thinking Puzzles: Five men are going to church. It starts to rain, and four of the men begin to run. When they arrive at the church, the four men who ran are soaking wet, whereas the fifth man, who didn’t run, is completely dry. How is this possible? Think Twice Riddles: If you are running a race, and you overtake the person in second place, what place do you move into? Word Riddles: SOS is read the same forwards, backwards, and even upside-down. What four-letter word also shares these properties? Number Puzzlers: How many letters are there in the answer to this question? You have an opportunity to buy a hen. In fact, you have been offered a choice between two quite remarkable animals. One of the hens produces six dozen dozen eggs per month, and the other produces a half dozen dozen. Admittedly, both seem impressive. Does it matter which hen you choose? Traditional Poetic Riddles: Five creatures cross a field of snow; But leave a single track behind Whose loops and bows are soon, I know, Unravelled by the mind. Coins, Cups, and Toothpicks Illustrated Riddles: A coin is dropped into an empty bottle and a cork is then inserted in the neck of the bottle. How is it possible to remove the coin without taking out the cork, or breaking the bottle?

    

    A longtime sufferer of depression, in 2007 he enrolled himself in a clinical trial for major depression (after his initial application for a minor depression trial was rejected). He wrote about his experience in a Harper’s magazine piece, which received a tremendous response from readers..• “Am I happy enough?”: This has been a pivotal question since America’s inception. Am I not happy enough because I am depressed? is a more recent version. Greenberg shows how depression has been manufactured—not as an illness, but as an idea about our suffering, its source, and its relief. He challenges us to look at depression in a new way..• A nation of depressives: In the twenty years since their introduction, antidepressants have become staples of our medicine chests—upwards of 30 million Americans are taking them at an annual cost of more than $10 billion. Even more important, Greenberg argues, it has become common, if not mandatory, to think of our unhappiness as a disease that can, and should, be treated by medication. Manufacturing Depression tells the story of how we got to this peculiar point in our history. .

    Now updated and expanded for the information age, this "A-Plus" read includes areas such as how to create a work environment, excel in class, use the library, do online research, and much more.

    Some chapters have been rewritten, making topics such as conjugation and nucleophilic substitution more accessible. Problems are provided which challenge the readers' understanding. read.

    'A focused snapshot of a brave new world.' - Nature In 2018 the world woke up to gene editing with a storm of controversy over twin girls born in China with genetic changes deliberately introduced by scientists – changes they will pass on to their own offspring. Genetic modification (GM) has been with us for 45 years now, but the new system known as CRISPR or gene editing can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago. But is it ethical to change the genetic material of organisms in a way that might be passed on to future generations? If a person is suffering from a lethal genetic disease, is it unethical to deny them this option? Who controls the application of this technology, when it makes ‘biohacking’ – perhaps of one’s own genome – a real possibility?Nessa Carey’s book is a thrilling and timely snapshot of a cutting-edge technology that will radically alter our futures and the way we prevent disease.

    hopeful news [for those] suffering from functional bowel disease.”  — New York Times Book ReviewDr. Gershon’s groundbreaking book fills the gap between what you need to know—and what your doctor has time to tell you.Dr. Michael Gershon has devoted his career to understanding the human bowel (the stomach, esophagus, small intestine, and colon). His thirty years of research have led to an extraordinary rediscovery: nerve cells in the gut that act as a brain. This "second brain" can control our gut all by itself. Our two brains—the one in our head and the one in our bowel—must cooperate. If they do not, then there is chaos in the gut and misery in the head—everything from "butterflies" to cramps, from diarrhea to constipation. Dr. Gershon's work has led to radical new understandings about a wide range of gastrointestinal problems including gastroenteritis, nervous stomach, and irritable bowel syndrome.The Second Brain represents a quantum leap in medical knowledge and is already benefiting patients whose symptoms were previously dismissed as neurotic or "it's all in your head."

    EMERGENCY 24/7: Nurses of the Emergency Room, portrays thirty-one nurses, each with a distinctive voice and unique view of what really goes on behind the closed doors of the secret and chaotic world of the emergency room. Also included are the moment-by-moment chronicles of eleven nurses who worked in New York City and Washington, D.C., on September 11, 2001. These compelling accounts give new perspectives on the horrors and heroics of that tragic day. Ranging from inspiring to heart-rending to outrageously funny, these gripping narratives make EMERGENCY 24/7 a fascinating and provocative book—a fitting tribute to the frontline nurses.

    Perfect to keep in scrub pockets, lab coats or white coats.

    That substance is vitamin D3. While it is called a vitamin, D3 is really a hormone. It was first used to treat a childhood bone disease called rickets. And, nearly all the research on the benefits of vitamin D3 has been done at doses that are 80 times lower than the optimal doses described in this book. This ground-breaking book is your opportunity to regain your health quickly, safely and easily. In The Optimal Dose, he reveals how vitamin D3 saved his own life when all else failed and explains how this essential vitamin is key to finding answers to your own health questions and challenges.