All the advances of modern life--the medical breakthroughs, the public health institutions, the rising standards of living--have given us each about twenty thousand extra days on average. There are few measures of human progress more astonishing than our increased longevity.This book is Steven Johnson's attempt to understand where that progress came from. How many of those extra twenty thousand days came from vaccines, or the decrease in famines, or seatbelts? What are the forces that now keep us alive longer? Behind each breakthrough lies an inspiring story of cooperative innovation, of brilliant thinkers bolstered by strong systems of public support and collaborative networks.But it is not enough simply to remind ourselves that progress is possible. How do we avoid decreases in life expectancy as our public health systems face unprecedented challenges? What current technologies or interventions that could reduce the impact of future crises are we somehow ignoring?

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    In fact, a plethora of parasites affect our behavior in ways we have barely begun to understand.  In this mind-bending book, McAuliffe reveals the eons-old war between parasites and other creatures that is playing out in our very own bodies. And more surprising still, she uncovers the decisive role that parasites may have played in the rise and demise of entire civilizations. Our obsession with cleanliness and our experience of disgust are both evolutionary tools for avoiding infection, but they evolved differently for different populations. Political, social, and religious differences among societies may be caused, in part, by the different parasites that prey on us. In the tradition of Jared Diamond’s Guns, Germs, and Steel and Neil Shubin’s Your Inner Fish, This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human.

    We are very pleased to be the first U.S. publisher to offer Ediths timeless watercolors.

    But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable?In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.

    Lesy has collected and arranged photographs taken between 1890 and 1910 by a Black River Falls photographer, Charles Van Schaik.

    

    Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    In an exhilarating, surprising exploration of our planet, Craig Childs takes readers on a firsthand journey through apocalypse, touching the truth behind the speculation. "Apocalyptic Planet" is a combination of science and adventure that reveals the ways in which our world is constantly moving toward its end and how we can change our place within the cycles and episodes that rule it. In this riveting narrative, Childs makes clear that ours is not a stable planet, that it is prone to sudden, violent natural disasters and extremes of climate. Alternate futures, many not so pretty, are constantly waiting in the wings. Childs refutes the idea of an apocalyptic end to the earth and finds clues to its more inevitable end in some of the most physically challenging places on the globe. He travels from the deserts of Chile, the driest in the world, to the genetic wasteland of central Iowa to the site of the drowned land bridge of the Bering Sea, uncovering the micro-cataclysms that predict the macro: forthcoming ice ages, super-volcanoes, and the conclusion of planetary life cycles. Childs delivers a sensual feast in his descriptions of the natural world and a bounty of unequivocal science that provides us with an unprecedented understanding of our future.

    Members of the phylum Mollusca are among the most ancient animals on the planet. Their shells provide homes for other animals, and across the ages, people have used shells not only as trinkets but also as a form of money, and as powerful symbols of sex and death, prestige and war.The science and natural history of shells are woven into a compelling narrative, revealing their cultural importance and the ways they have been used by humans over the millennia. (Seashells have even been tapped as a source of mind-bending drugs.) Marine biologist Helen Scales shows how seashells have been sculpted by the fundamental rules of mathematics and evolution; how they gave us color, gems, food, and new medicines.After surviving multiple mass extinctions millions of years ago, molluscs and their shells still face an onslaught of anthropogenic challenges, including climate change and corrosive oceans. But rather than dwelling on all that is lost, Scales emphasizes that seashells offer an accessible way to reconnect people with nature, helping to bridge the gap between ourselves and the living world. Spirals in Time: The Secret Life and Curious Afterlife of Seashells shows why nature matters, and reveals the hidden wonders that you can hold in the palm of your hand.

    Covering a wide array of artistic mediums, this fascinating collection also contains infographics about artistic movements throughout history, statistics about women's representation in museums, and notable works by women. Women in Art celebrates the success of the bold female creators who inspired the world and paved the way for the next generation of artists.

    In his groundbreaking Before the Dawn, Wade reveals humanity's origins as never before--a journey made possible only recently by genetic science, whose incredible findings have answered such questions as: What was the first human language like? How large were the first societies, and how warlike were they? When did our ancestors first leave Africa, and by what route did they leave? By eloquently solving these and numerous other mysteries, Wade offers nothing less than a uniquely complete retelling of a story that began 500 centuries ago.

    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    In Never Home Alone, biologist Rob Dunn introduces us to the nearly 200,000 species living with us in our own homes, from the Egyptian meal moths in our cupboards and camel crickets in our basements to the lactobacillus lounging on our kitchen counters. You are not alone. Yet, as we obsess over sterilizing our homes and separating our spaces from nature, we are unwittingly cultivating an entirely new playground for evolution. These changes are reshaping the organisms that live with us -- prompting some to become more dangerous, while undermining those species that benefit our bodies or help us keep more threatening organisms at bay. No one who reads this engrossing, revelatory book will look at their homes in the same way again.