The Other Brain: From Dementia to Schizophrenia, How New Discoveries about the Brain Are Revolutionizing Medicine and Science
R. Douglas Fields - 2008
The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.
How To: Absurd Scientific Advice for Common Real-World Problems
Randall Munroe - 2019
How To is a guide to the third kind of approach. It's full of highly impractical advice for everything from landing a plane to digging a hole.Bestselling author and cartoonist Randall Munroe explains how to predict the weather by analyzing the pixels of your Facebook photos. He teaches you how to tell if you're a baby boomer or a 90's kid by measuring the radioactivity of your teeth. He offers tips for taking a selfie with a telescope, crossing a river by boiling it, and powering your house by destroying the fabric of space-time. And if you want to get rid of the book once you're done with it, he walks you through your options for proper disposal, including dissolving it in the ocean, converting it to a vapor, using tectonic plates to subduct it into the Earth's mantle, or launching it into the Sun.By exploring the most complicated ways to do simple tasks, Munroe doesn't just make things difficult for himself and his readers. As he did so brilliantly in What If?, Munroe invites us to explore the most absurd reaches of the possible. Full of clever infographics and amusing illustrations, How To is a delightfully mind-bending way to better understand the science and technology underlying the things we do every day.
Calculus, Better Explained: A Guide To Developing Lasting Intuition
Kalid Azad - 2015
Learn the essential concepts using concrete analogies and vivid diagrams, not mechanical definitions. Calculus isn't a set of rules, it's a specific, practical viewpoint we can apply to everyday thinking. Frustrated With Abstract, Mechanical Lessons? I was too. Despite years of classes, I didn't have a strong understanding of calculus concepts. Sure, I could follow mechanical steps, but I had no lasting intuition. The classes I've seen are too long, taught in the wrong order, and without solid visualizations. Here's how this course is different: 1) It gets to the point. A typical class plods along, saving concepts like Integrals until Week 8. I want to see what calculus can offer by Minute 8. Each compact, tightly-written lesson can be read in 15 minutes. 2) Concepts are taught in their natural order. Most classes begin with the theory of limits, a technical concept discovered 150 years after calculus was invented. That's like putting a new driver into a Formula-1 racecar on day 1. We can begin with the easy-to-grasp concepts discovered 2000 years ago. 3) It has vivid analogies and visualizations. Calculus is usually defined as the "study of change"... which sounds like history or geology. Instead of an abstract definition, we'll see calculus a step-by-step viewpoint to explore patterns. 4) It's written by a human, for humans. I'm not a haughty professor or strict schoolmarm. I'm a friend who saw a fun way to internalize some difficult ideas. This course is a chat over coffee, not a keep-your-butt-in-your-seat lecture. The goal is to help you grasp the Aha! moments behind calculus in hours, not a painful semester (or a decade, in my case). Join Thousands Of Happy Readers Here's a few samples of anonymous feedback as people went through the course. The material covers a variety of levels, whether you're looking for intuitive appreciation or the specifics of the rules. "I've done all of this stuff before, and I do understand calculus intuitively, but this was the most fun I've had going through this kind of thing. The informal writing and multitude of great analogies really helps this become an enjoyable read and the rest is simple after that - you make this seem easy, but at the same time, you aren't doing it for us…This is what math education is supposed to be like :)" "I have psychology and medicine background so I relate your ideas to my world. To me the most useful idea was what each circle production feels like. Rings are natural growth…Slices are automatable chunks and automation cheapens production… Boards in the shape on an Arch are psychologically most palatable for work (wind up, hard part, home stretch). Brilliant and kudos, from one INTP to another." "I like how you're introducing both derivatives and integrals at the same time - it's really helps with understanding the relationship between them. Also, I appreciate how you're coming from such a different angle than is traditionally taken - it's always interesting to see where you decide to go next." "That was breathtaking. Seriously, mail my air back please, I've grown used to it. Beautiful work, thank you. Lesson 15 was masterful. I am starting to feel calculus. "d/dx is good" (sorry, couldn't resist!)."
The Calculus Wars: Newton, Leibniz, and the Greatest Mathematical Clash of All Time
Jason Socrates Bardi - 2006
But a dispute over its discovery sowed the seeds of discontent between two of the greatest scientific giants of all time - Sir Isaac Newton and Gottfried Wilhelm Leibniz." "Today Newton and Leibniz are generally considered the twin independent inventors of calculus. They are both credited with giving mathematics its greatest push forward since the time of the Greeks. Had they known each other under different circumstances, they might have been friends. But in their own lifetimes, the joint glory of calculus was not enough for either and each declared war against the other, openly and in secret." This long and bitter dispute has been swept under the carpet by historians - perhaps because it reveals Newton and Leibniz in their worst light - but The Calculus Wars tells the full story in narrative form for the first time. This history ultimately exposes how these twin mathematical giants were brilliant, proud, at times mad, and in the end completely human.
Standard Deviations: Flawed Assumptions, Tortured Data, and Other Ways to Lie with Statistics
Gary Smith - 2014
In Standard Deviations, economics professor Gary Smith walks us through the various tricks and traps that people use to back up their own crackpot theories. Sometimes, the unscrupulous deliberately try to mislead us. Other times, the well-intentioned are blissfully unaware of the mischief they are committing. Today, data is so plentiful that researchers spend precious little time distinguishing between good, meaningful indicators and total rubbish. Not only do others use data to fool us, we fool ourselves.With the breakout success of Nate Silver’s The Signal and the Noise, the once humdrum subject of statistics has never been hotter. Drawing on breakthrough research in behavioral economics by luminaries like Daniel Kahneman and Dan Ariely and taking to task some of the conclusions of Freakonomics author Steven D. Levitt, Standard Deviations demystifies the science behind statistics and makes it easy to spot the fraud all around.
Sir Cumference and the First Round Table: A Math Adventure
Cindy Neuschwander - 1997
King Arthur was a good ruler, but now he needs a good ruler. What would you do if the neighboring kingdom were threatening war? Naturally, you'd call your strongest and bravest knights together to come up with a solution. But when your conference table causes more problems than the threat of your enemy, you need expert help. Enter Sir Cumference, his wife Lady Di of Ameter, and their son Radius. With the help of the carpenter, Geo of Metry, this sharp-minded team designs the perfect table conducive to discussing the perfect plan for peace. The first in Sir Cumference series, SIR CUMFERENCE AND THE FIRST ROUND TABLE makes math fun and accessible for everyone.
Super Crunchers: Why Thinking-By-Numbers Is the New Way to Be Smart
Ian Ayres - 2007
In this lively and groundbreaking new book, economist Ian Ayres shows how today's best and brightest organizations are analyzing massive databases at lightening speed to provide greater insights into human behavior. They are the Super Crunchers. From internet sites like Google and Amazon that know your tastes better than you do, to a physician's diagnosis and your child's education, to boardrooms and government agencies, this new breed of decision makers are calling the shots. And they are delivering staggeringly accurate results. How can a football coach evaluate a player without ever seeing him play? Want to know whether the price of an airline ticket will go up or down before you buy? How can a formula outpredict wine experts in determining the best vintages? Super crunchers have the answers. In this brave new world of equation versus expertise, Ayres shows us the benefits and risks, who loses and who wins, and how super crunching can be used to help, not manipulate us.Gone are the days of solely relying on intuition to make decisions. No businessperson, consumer, or student who wants to stay ahead of the curve should make another keystroke without reading Super Crunchers.
The Trouble with Physics: The Rise of String Theory, the Fall of a Science and What Comes Next
Lee Smolin - 2006
For more than two centuries, our understanding of the laws of nature expanded rapidly. But today, despite our best efforts, we know nothing more about these laws than we knew in the 1970s. Why is physics suddenly in trouble? And what can we do about it?One of the major problems, according to Smolin, is string theory: an ambitious attempt to formulate a “theory of everything” that explains all the particles and forces of nature and how the universe came to be. With its exotic new particles and parallel universes, string theory has captured the public’s imagination and seduced many physicists.But as Smolin reveals, there’s a deep flaw in the theory: no part of it has been tested, and no one knows how to test it. In fact, the theory appears to come in an infinite number of versions, meaning that no experiment will ever be able to prove it false. As a scientific theory, it fails. And because it has soaked up the lion’s share of funding, attracted some of the best minds, and effectively penalized young physicists for pursuing other avenues, it is dragging the rest of physics down with it.With clarity, passion, and authority, Smolin charts the rise and fall of string theory and takes a fascinating look at what will replace it. A group of young theorists has begun to develop exciting ideas that, unlike string theory, are testable. Smolin not only tells us who and what to watch for in the coming years, he offers novel solutions for seeking out and nurturing the best new talent—giving us a chance, at long last, of finding the next Einstein.
Book of Proof
Richard Hammack - 2009
It is a bridge from the computational courses (such as calculus or differential equations) that students typically encounter in their first year of college to a more abstract outlook. It lays a foundation for more theoretical courses such as topology, analysis and abstract algebra. Although it may be more meaningful to the student who has had some calculus, there is really no prerequisite other than a measure of mathematical maturity. Topics include sets, logic, counting, methods of conditional and non-conditional proof, disproof, induction, relations, functions and infinite cardinality.
What Intelligence Tests Miss: The Psychology of Rational Thought
Keith E. Stanovich - 2009
However, such critiques imply that though intelligence tests may miss certain key noncognitive areas, they encompass most of what is important in the cognitive domain. In this book, Keith E. Stanovich challenges this widely held assumption.Stanovich shows that IQ tests (or their proxies, such as the SAT) are radically incomplete as measures of cognitive functioning. They fail to assess traits that most people associate with “good thinking,” skills such as judgment and decision making. Such cognitive skills are crucial to real-world behavior, affecting the way we plan, evaluate critical evidence, judge risks and probabilities, and make effective decisions. IQ tests fail to assess these skills of rational thought, even though they are measurable cognitive processes. Rational thought is just as important as intelligence, Stanovich argues, and it should be valued as highly as the abilities currently measured on intelligence tests.
Rationality: From AI to Zombies
Eliezer Yudkowsky - 2015
Real rationality, of the sort studied by psychologists, social scientists, and mathematicians. The kind of rationality where you make good decisions, even when it's hard; where you reason well, even in the face of massive uncertainty; where you recognize and make full use of your fuzzy intuitions and emotions, rather than trying to discard them. In "Rationality: From AI to Zombies," Eliezer Yudkowsky explains the science underlying human irrationality with a mix of fables, argumentative essays, and personal vignettes. These eye-opening accounts of how the mind works (and how, all too often, it doesn't!) are then put to the test through some genuinely difficult puzzles: computer scientists' debates about the future of artificial intelligence (AI), physicists' debates about the relationship between the quantum and classical worlds, philosophers' debates about the metaphysics of zombies and the nature of morality, and many more. In the process, "Rationality: From AI to Zombies" delves into the human significance of correct reasoning more deeply than you'll find in any conventional textbook on cognitive science or philosophy of mind. A decision theorist and researcher at the Machine Intelligence Research Institute, Yudkowsky published earlier drafts of his writings to the websites Overcoming Bias and Less Wrong. "Rationality: From AI to Zombies" compiles six volumes of Yudkowsky's essays into a single electronic tome. Collectively, these sequences of linked essays serve as a rich and lively introduction to the science—and the art—of human rationality.
Logicomix: An Epic Search for Truth
Apostolos Doxiadis - 2009
This graphic novel recounts the spiritual odyssey of philosopher Bertrand Russell. In his agonized search for absolute truth, he crosses paths with thinkers like Gottlob Frege, David Hilbert & Kurt Gödel, & finds a passionate student in Ludwig Wittgenstein. But his most ambitious goal—to establish unshakable logical foundations of mathematics—continues to loom before him. Thru love & hate, peace & war, he persists in the mission threatening to claim both his career & happiness, finally driving him to the brink of insanity. This story is at the same time a historical novel & an accessible explication of some of the biggest ideas of mathematics & modern philosophy. With rich characterizations & atmospheric artwork, it spins the pursuit of such ideas into a satisfying tale. Probing, layered, the book throws light on Russell’s inner struggles while setting them in the context of the timeless questions he tried to answer. At its heart, Logicomix is a story about the conflict between ideal rationality & the flawed fabric of reality.
How to Create a Mind: The Secret of Human Thought Revealed
Ray Kurzweil - 2012
In How to Create a Mind, Kurzweil presents a provocative exploration of the most important project in human-machine civilization—reverse engineering the brain to understand precisely how it works and using that knowledge to create even more intelligent machines.Kurzweil discusses how the brain functions, how the mind emerges from the brain, and the implications of vastly increasing the powers of our intelligence in addressing the world’s problems. He thoughtfully examines emotional and moral intelligence and the origins of consciousness and envisions the radical possibilities of our merging with the intelligent technology we are creating.Certain to be one of the most widely discussed and debated science books of the year, How to Create a Mind is sure to take its place alongside Kurzweil’s previous classics which include Fantastic Voyage: Live Long Enough to Live Forever and The Age of Spiritual Machines.
Poincare's Prize: The Hundred-Year Quest to Solve One of Math's Greatest Puzzles
George G. Szpiro - 2007
Amazingly, the story unveiled in it is true.In the world of math, the Poincaré Conjecture was a holy grail. Decade after decade the theorem that informs how we understand the shape of the universe defied every effort to prove it. Now, after more than a century, an eccentric Russian recluse has found the solution to one of the seven greatest math problems of our time, earning the right to claim the first one-million-dollar Millennium math prize.George Szpiro begins his masterfully told story in 1904 when Frenchman Henri Poincaré formulated a conjecture about a seemingly simple problem. Imagine an ant crawling around on a large surface. How would it know whether the surface is a flat plane, a round sphere, or a bagel- shaped object? The ant would need to lift off into space to observe the object. How could you prove the shape was spherical without actually seeing it? Simply, this is what Poincaré sought to solve.In fact, Poincaré thought he had solved it back at the turn of the twentieth century, but soon realized his mistake. After four more years' work, he gave up. Across the generations from China to Texas, great minds stalked the solution in the wilds of higher dimensions. Among them was Grigory Perelman, a mysterious Russian who seems to have stepped out of a Dostoyevsky novel. Living in near poverty with his mother, he has refused all prizes and academic appointments, and rarely talks to anyone, including fellow mathematicians. It seemed he had lost the race in 2002, when the conjecture was widely but, again, falsely reported as solved. A year later, Perelman dropped three papers onto the Internet that not only proved the Poincaré Conjecture but enlightened the universe of higher dimensions, solving an array of even more mind-bending math with implications that will take an age to unravel. After years of review, his proof has just won him a Fields Medal--the 'Nobel of math'--awarded only once every four years. With no interest in fame, he refused to attend the ceremony, did not accept the medal, and stayed home to watch television.Perelman is a St. Petersburg hero, devoted to an ascetic life of the mind. The story of the enigma in the shape of space that he cracked is part history, part math, and a fascinating tale of the most abstract kind of creativity.
The Bell Curve: Intelligence and Class Structure in American Life
Richard J. Herrnstein - 1994
The controversial book linking intelligence to class and race in modern society, and what public policy can do to mitigate socioeconomic differences in IQ, birth rate, crime, fertility, welfare, and poverty.