Book picks similar to
Neurobiology of Mental Illness by Eric J. Nestler


science
neuroscience
psychiatry
counseling-and-psychology

Projections: A Story of Human Emotions


Karl Deisseroth - 2021
    In Projections, he combines his groundbreaking access to the brain's inner circuitry with a deep empathy for his patients to examine what mental illness reveals about the mind and the origin of human feelings--how the broken can illuminate the unbroken. An internationally acclaimed professor of bioengineering and psychiatry at Stanford, Deisseroth's true passion is clinical psychiatry, and it is the stories of his patients that form the backbone of Projections. Through these case studies, he tells the larger story of how we can understand the physical and biological origins of human emotion in the brain. As such, he describes vividly how humans experience feelings both in the simple and ancient circuits of our brains and in the poignant moments of suffering in our daily lives. The stories of Deisseroth's patients are rich with humanity and shine an unprecedented light on the self and the ways in which it breaks down. A young woman with an eating disorder reveals how the mind can rebel against the brain's most primitive drives of hunger and thirst; while an older gentleman, smothered into silence by depression and dementia, illuminates how humans evolved to feel joy and its absence; and a lonely Uyghur woman far from home teaches the importance of rich social bonds. An illuminating and essential work, Projections transforms the way we understand the brain as a biological and as an emotional object.A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories“[A] scintillating and moving analysis of the human brain and emotions.”—Nature“Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate

The Boy Who Couldn't Stop Washing: The Experience and Treatment of Obsessive-Compulsive Disorder


Judith L. Rapoport - 1989
    Another sufferer must check her stove hundreds of times daily to make sure she has turned it off. And one woman, in an effort to ensure that her eyebrows are symmetrical, finally plucks out every hair. All of these people are suffering from Obsessive-Compulsive Disorder (OCD), an emotionally debilitating sickness that afflicts up to six million Americans. Cleaning, counting, washing, avoiding, checking—these are some of the pointless rituals that sufferers are powerless to stop. Now a distinguished psychiatrist and expert on OCD reveals exciting breakthroughs in diagnosis, successful new behaviorist therapies and drug treatments, as well as lists of resources and references. Drawing on the extraordinary experiences of her patients, Dr. Judith Rapoport unravels the mysteries surrounding this irrational disorder . . . and provides prescriptions for action that promise hope and help.

Patient H.M.: A Story of Memory, Madness, and Family Secrets


Luke Dittrich - 2016
    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

The Nocturnal Brain: Nightmares, Neuroscience, and the Secret World of Sleep


Guy Leschziner - 2019
    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

The Myth of Mental Illness: Foundations of a Theory of Personal Conduct


Thomas Szasz - 1961
    "Bold and often brilliant.”—Science "It is no exaggeration to state that Szasz's work raises major social issues which deserve the attention of policy makers and indeed of all informed and socially conscious Americans...Quite probably he has done more than any other man to alert the American public to the potential dangers of an excessively psychiatrized society.”—Edwin M. Schur, Atlantic

The Maudsley Prescribing Guidelines in Psychiatry


David M. Taylor - 1999
    Where do you look for information when transferring a patient from one drug to another? Where do you find a clear overview when dealing with a complex patient (e.g, with co-morbid epilepsy or liver disease or HIV infection)? Where can you seek advice on prescribing psychotropics during pregnancy? "The Maudsley Prescribing Guidelines in Psychiatry"! The leading clinical reference for handling prescribing problems as encountered in daily practice and for formulating prescribing policy.Evidence-based and written by expertsThis book is the essential guide for anyone responsible for prescribing, dispensing or administering drugs for patients with mental health disorders. All the evidence has been reviewed and summarized succinctly by an expert team of psychiatrists and pharmacists.New content and improved formatThis new edition makes greater use of tables and boxes to facilitate quick reference and includes new sections on cytochrome-mediated interactions and psychiatric side effects of non-psychotropic drugs.Clinically relevantChapters address plasma monitoring, schizophrenia, bipolar disorder, depression and anxiety, children and adolescents, substance abuse and special patient groups. Each section has a full reference list. The book covers prescribing drugs outside their licensed indications and their interaction with substances such as alcohol, nicotine and caffeine.Useful for all levels of experienceTrainees will gain important information regarding the rational, safe and effective use of medications for patients with mental illness. Experienced clinicians will find excellent guidance regarding more complex issues that they may not encounter regularly.Why the Maudsley Prescribing Guidelines in Psychiatry?Long recognized as an international trailblazer in mental health care, the Maudsley Hospital earned its reputation for excellence in both in-patient and community care. It is highly regarded for its research, and pioneered the use of clinical neuroscience. You can trust "The Maudsley Prescribing Guidelines in Psychiatry" to be scientifically sound and clinically effective.

The Executive Brain: Frontal Lobes and the Civilized Mind


Elkhonon Goldberg - 2001
    Crucial for all high-order functioning, it is only in humans that the frontal lobes are so highly developed. They hold the key to our judgment, our social and ethical behavior, our imagination, indeed, to our soul. The author shows how the frontal lobes enable us to engage in complex mental processes, how vulnerable they are to injury, and how devastating the effects of damage often are, leading to chaotic, disorganized, asocial, and even criminal behavior.Made up of fascinating case histories and anecdotes, Goldberg's book offers a panorama of state-of-the-art ideas and advances in cognitive neuroscience. It is also an intellectual memoir, filled with vignettes about the author's early training with the great Russian neuropsychologist A.R. Luria, Goldberg's escape from the Soviet Union, and his later interactions with patients and professionals around the world.

Weekends at Bellevue: Nine Years on the Night Shift at the Psych E.R.


Julie Holland - 2009
    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

Cure: A Journey into the Science of Mind Over Body


Jo Marchant - 2016
    Recently, however, serious scientists from a range of fields have been uncovering evidence that our thoughts, emotions and beliefs can ease pain, heal wounds, fend off infection and heart disease and even slow the progression of AIDS and some cancers.In Cure, award-winning science writer Jo Marchant travels the world to meet the physicians, patients and researchers on the cutting edge of this new world of medicine. We learn how meditation protects against depression and dementia, how social connections increase life expectancy and how patients who feel cared for recover from surgery faster. We meet Iraq war veterans who are using a virtual arctic world to treat their burns and children whose ADHD is kept under control with half the normal dose of medication. We watch as a transplant patient uses the smell of lavender to calm his hostile immune system and an Olympic runner shaves vital seconds off his time through mind-power alone.Drawing on the very latest research, Marchant explores the vast potential of the mind's ability to heal, lays out its limitations and explains how we can make use of the findings in our own lives. With clarity and compassion, Cure points the way towards a system of medicine that treats us not simply as bodies but as human beings.

Visual Intelligence: How We Create What We See


Donald D. Hoffman - 1998
    Hoffman aptly demonstrates the mysterious constructive powers of our eye-brain machines using lots of simple drawings and diagrams to illustrate basic rules of the visual road. Many of the examples are familiar optical illusions--perspective-confounding cubes, a few lines that add up to a more complex shape than seems right. Hoffman also takes a cue from Oliver Sacks, employing anecdotes about people with various specific visual malfunctions to both further his mechanical explanation of visual intelligence and drive home how important this little-understood aspect of cognition can be in our lives. An especially intriguing example involves a boy, blind from birth, who is surgically given the power to see. At first, he is completely unable to visually distinguish objects familiar by touch, such as the cat and the dog. Other poignant examples show clearly how image construction is normally linked to our emotional well-being and sense of place. Visual Intelligence is a fascinating, confounding look (as it were) at an aspect of human physiology and psychology that very few of us think about much at all. --Therese Littleton

Clinical Psychopharmacology Made Ridiculously Simple


John D. Preston - 1990
    Pocket-sized text provides an overview of clinical psychopharmacology. Surveys psychotropic medications focusing on diagnostic findings. Discusses medications for depression, bipolar illness, anxiety disorders, psychotic disorders, and cites real-life case examples. Previous edition: c2003. Softcover.Current edition is a 2011 update (i.e. copyright 2011Thanks...John Preston...author

My Stroke of Insight: A Brain Scientist's Personal Journey


Jill Bolte Taylor - 2006
    Through the eyes of a curious scientist, she watched her mind deteriorate whereby she could not walk, talk, read, write, or recall any of her life. Because of her understanding of the brain, her respect for the cells in her body, and an amazing mother, Jill completely recovered. In My Stroke of Insight, she shares her recommendations for recovery and the insight she gained into the unique functions of the two halves of her brain. When she lost the skills of her left brain, her consciousness shifted away from normal reality where she felt "at one with the universe." Taylor helps others not only rebuild their brains from trauma, but helps those of us with normal brains better understand how we can consciously influence the neural circuitry underlying what we think, how we feel and how we react to life's circumstances.

The Examined Life: How We Lose and Find Ourselves


Stephen Grosz - 2012
    These beautifully rendered tales illuminate the fundamental pathways of life from birth to death.A woman finds herself daydreaming as she returns home from a business trip; a young man loses his wallet. We learn, too, from more extreme examples: the patient who points an unloaded gun at a police officer, the compulsive liar who convinces his wife he's dying of cancer. The stories invite compassionate understanding, suggesting answers to the questions that compel and disturb us most about love and loss, parents and children, work and change. The resulting journey will spark new ideas about who we are and why we do what we do.

When the Air Hits Your Brain: Tales of Neurosurgery


Frank T. Vertosick Jr. - 1996
    In other words, by all of us."--Dr. Bernie Siegel, author of Love, Medicine and MiraclesRule One for the neurologist in residence: "You ain't never the same when the air hits your brain." In this fascinating book, Dr. Frank Vertosick brings that fact to life through intimate portraits of patients and unsparing yet gripping descriptions of brain surgery.With insight, humor, and poignancy, Dr. Vertosick chronicles his remarkable evolution from naive young intern to world-class neurosurgeon, where he faced, among other challenges, a six week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22 caliber bullet lodged in his skull. In candid detail, WHEN THE AIR HITS YOUR BRAIN illuminates both the mysteries of the mind and the realities of the operating room."Riveting."--Publishers Weekly

Left Brain, Right Brain: Perspectives from Cognitive Neuroscience


Sally P. Springer - 1950
    It reviews the historical context from which the field emerged, focusing on behavioural implications, and intergrating new developments in cognitive neuroscience. The authors cover current neuroimaging techniques such as PET, SPECT, EEG and MEG. This edition has been updated to incorporate present thinking within hemispheric asymmetry.