As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    Written in conjunction with Samuel Crowther, "My Life and Work" chronicles the rise and success of one of the greatest American entrepreneurs and businessmen. Henry Ford and the Ford Motor Company will forever be identified with early 20th century American industrialism. The innovations to business and direct impact on the American economy of Henry Ford and his company are immeasurable. His story is brilliantly chronicled in this classic American biography.

    Twice every three days another citizen is shot, stabbed, or bludgeoned to death. At the center of this hurricane of crime is the city's homicide unit, a small brotherhood of hard men who fight for whatever justice is possible in a deadly world.David Simon was the first reporter ever to gain unlimited access to a homicide unit, and this electrifying book tells the true story of a year on the violent streets of an American city. The narrative follows Donald Worden, a veteran investigator; Harry Edgerton, a black detective in a mostly white unit; and Tom Pellegrini, an earnest rookie who takes on the year's most difficult case, the brutal rape and murder of an eleven-year-old girl.Originally published fifteen years ago, Homicide became the basis for the acclaimed television show of the same name. This new edition--which includes a new introduction, an afterword, and photographs--revives this classic, riveting tale about the men who work on the dark side of the American experience.

    Suppose that different food inspectors give different ratings to indistinguishable restaurants — or that when a company is handling customer complaints, the resolution depends on who happens to be handling the particular complaint. Now imagine that the same doctor, the same judge, the same inspector, or the same company official makes different decisions, depending on whether it is morning or afternoon, or Monday rather than Wednesday. These are examples of noise: variability in judgments that should be identical.   In Noise, Daniel Kahneman, Cass R. Sunstein, and Olivier Sibony show how noise contributes significantly to errors in all fields, including medicine, law, economic forecasting, police behavior, food safety, bail, security checks at airports, strategy, and personnel selection. And although noise can be found wherever people make judgments and decisions, individuals and organizations alike are commonly oblivious to the role of chance in their judgments and in their actions.   Drawing on the latest findings in psychology and behavioral economics, and the same kind of diligent, insightful research that made Thinking, Fast and Slow and Nudge groundbreaking New York Times bestsellers, Noise explains how and why humans are so susceptible to noise in judgment — and what we can do about it.

    We watch him navigate a fraught relationship with a lonely uncle in jail who—as he degenerates into madness— continues to plead for the support of his conflicted nephew. And we cringe as he gets outed as a “moby” at a Tea Party rally. In moments like these, we can’t help but ask ourselves: How far would we go for our own family members, and when is someone simply too far gone to save? Are there truly “bad people,” and if so, should we change them? With a perfect combination of humor and pathos, these essays, peppered with Kreider’s signature cartoons, leave us with newfound wisdom and a unique prism through which to examine our own chaotic journeys through life.Uncompromisingly candid, sometimes mercilessly so, these comically illustrated essays are rigorous exercises in self-awareness and self-reflection. These are the conversations you have only with best friends or total strangers, late at night over drinks, near closing time.

    This has always been the case, no matter how often that certainty has failed. Though no generation believes there’s nothing left to learn, every generation unconsciously assumes that what has already been defined and accepted is (probably) pretty close to how reality will be viewed in perpetuity. And then, of course, time passes. Ideas shift. Opinions invert. What once seemed reasonable eventually becomes absurd, replaced by modern perspectives that feel even more irrefutable and secure—until, of course, they don’t.But What If We’re Wrong? visualizes the contemporary world as it will appear to those who'll perceive it as the distant past. Chuck Klosterman asks questions that are profound in their simplicity: How certain are we about our understanding of gravity? How certain are we about our understanding of time? What will be the defining memory of rock music, five hundred years from today? How seriously should we view the content of our dreams? How seriously should we view the content of television? Are all sports destined for extinction? Is it possible that the greatest artist of our era is currently unknown (or—weirder still—widely known, but entirely disrespected)? Is it possible that we “overrate” democracy? And perhaps most disturbing, is it possible that we’ve reached the end of knowledge?Kinetically slingshotting through a broad spectrum of objective and subjective problems, But What If We’re Wrong? is built on interviews with a variety of creative thinkers—George Saunders, David Byrne, Jonathan Lethem, Kathryn Schulz, Neil deGrasse Tyson, Brian Greene, Junot Díaz, Amanda Petrusich, Ryan Adams, Nick Bostrom, Dan Carlin, and Richard Linklater, among others—interwoven with the type of high-wire humor and nontraditional analysis only Klosterman would dare to attempt. It’s a seemingly impossible achievement: a book about the things we cannot know, explained as if we did. It’s about how we live now, once “now” has become “then.”

    There, the vending machines were stocked with painkillers, and the staff turnover was dizzying. In the new year, she traveled to North Carolina to work at a call center, a place where even bathroom breaks were timed to the second. And finally, Guendelsberger was hired at a San Francisco McDonald's, narrowly escaping revenge-seeking customers who pelted her with condiments.Across three jobs, and in three different parts of the country, Guendelsberger directly took part in the revolution changing the U.S. workplace. On the Clock takes us behind the scenes of the fastest-growing segment of the American workforce to understand the future of work in America--and its present. Until robots pack boxes, resolve billing issues, and make fast food, human beings supervised by AI will continue to get the job done. Guendelsberger shows us how workers went from being the most expensive element of production to the cheapest--and how low-wage jobs have been remade to serve the ideals of efficiency, at the cost of humanity.On the Clock explores the lengths that half of Americans will go to to make a living, offering not only a better understanding of the modern workplace, but also surprising solutions to make work more humane.

    Odessa is not known to be a town big on dreams, but the Panthers help keep the hopes and dreams of this small, dusty town going. Socially and racially divided, its fragile economy follows the treacherous boom-bust path of the oil business.In bad times, the unemployment rate barrels out of control; in good times, its murder rate skyrockets. But every Friday night from September to December, when the Permian High School Panthers play football, this West Texas town becomes a place where dreams can come true. With frankness and compassion, Bissinger chronicles one of the Panthers' dramatic seasons and shows how single-minded devotion to the team shapes the community and inspires-and sometimes shatters-the teenagers who wear the Panthers' uniforms. Includes Reader's Group Guide inside. Now a major motion picture starring Billy Bob Thorton.

    That’s a mistake, Tim Harford says in The Data Detective. We shouldn’t be suspicious of statistics—we need to understand what they mean and how they can improve our lives: they are, at heart, human behavior seen through the prism of numbers and are often “the only way of grasping much of what is going on around us.” If we can toss aside our fears and learn to approach them clearly—understanding how our own preconceptions lead us astray—statistics can point to ways we can live better and work smarter.As “perhaps the best popular economics writer in the world” (New Statesman), Tim Harford is an expert at taking complicated ideas and untangling them for millions of readers. In The Data Detective, he uses new research in science and psychology to set out ten strategies for using statistics to erase our biases and replace them with new ideas that use virtues like patience, curiosity, and good sense to better understand ourselves and the world. As a result, The Data Detective is a big-idea book about statistics and human behavior that is fresh, unexpected, and insightful.

    At nineteen, Jake Adelstein went to Japan in search of peace and tranquility. What he got was a life of crime . . . crime reporting, that is, at the prestigious Yomiuri Shinbun. For twelve years of eighty-hour workweeks, he covered the seedy side of Japan, where extortion, murder, human trafficking, and corruption are as familiar as ramen noodles and sake. But when his final scoop brought him face to face with Japan’s most infamous yakuza boss—and the threat of death for him and his family—Adelstein decided to step down . . . momentarily. Then, he fought back.In Tokyo Vice, Adelstein tells the riveting, often humorous tale of his journey from an inexperienced cub reporter—who made rookie mistakes like getting into a martial-arts battle with a senior editor—to a daring, investigative journalist with a price on his head. With its vivid, visceral descriptions of crime in Japan and an exploration of the world of modern-day yakuza that even few Japanese ever see, Tokyo Vice is a fascination, and an education, from first to last.

    Tracy Kidder got a preview of this world in the late 1970s when he observed the engineers of Data General design and build a new 32-bit minicomputer in just one year. His thoughtful, prescient book, The Soul of a New Machine, tells stories of 35-year-old "veteran" engineers hiring recent college graduates and encouraging them to work harder and faster on complex and difficult projects, exploiting the youngsters' ignorance of normal scheduling processes while engendering a new kind of work ethic.These days, we are used to the "total commitment" philosophy of managing technical creation, but Kidder was surprised and even a little alarmed at the obsessions and compulsions he found. From in-house political struggles to workers being permitted to tease management to marathon 24-hour work sessions, The Soul of a New Machine explores concepts that already seem familiar, even old-hat, less than 20 years later. Kidder plainly admires his subjects; while he admits to hopeless confusion about their work, he finds their dedication heroic. The reader wonders, though, what will become of it all, now and in the future. —Rob Lightner

    Seismic shifts during a single generation have created a country of winners and losers, allowing unprecedented freedom while rending the social contract, driving the political system to the verge of breakdown, and setting citizens adrift to find new paths forward. In The Unwinding, George Packer, author of The Assassins' Gate: America in Iraq, tells the story of the United States over the past three decades in an utterly original way, with his characteristically sharp eye for detail and gift for weaving together complex narratives.The Unwinding journeys through the lives of several Americans, including Dean Price, the son of tobacco farmers, who becomes an evangelist for a new economy in the rural South; Tammy Thomas, a factory worker in the Rust Belt trying to survive the collapse of her city; Jeff Connaughton, a Washington insider oscillating between political idealism and the lure of organized money; and Peter Thiel, a Silicon Valley billionaire who questions the Internet's significance and arrives at a radical vision of the future. Packer interweaves these intimate stories with biographical sketches of the era's leading public figures, from Newt Gingrich to Jay-Z, and collages made from newspaper headlines, advertising slogans, and song lyrics that capture the flow of events and their undercurrents.The Unwinding portrays a superpower in danger of coming apart at the seams, its elites no longer elite, its institutions no longer working, its ordinary people left to improvise their own schemes for success and salvation. Packer's novelistic and kaleidoscopic history of the new America is his most ambitious work to date.One of the iTunes Bookstore's "Ten Books You Must Read This Summer"

    By telling the story of her life and the lives of the people she loves, Smarsh challenges us to look more closely at the class divide in our country and examine the myths about people thought to be less because they earn less. Her personal history affirms the corrosive impact intergenerational poverty can have on individuals, families, and communities, and she explores this idea as lived experience, metaphor, and level of consciousness. Smarsh was born a fifth generation Kansas wheat farmer on her paternal side and the product of generations of teen mothers on her maternal side. Through her experiences growing up as the daughter of a dissatisfied young mother and raised predominantly by her grandmother on a farm thirty miles west of Wichita, we are given a unique and essential look into the lives of poor and working class Americans living in the heartland. Combining memoir with powerful analysis and cultural commentary, Heartland is an uncompromising look at class, identity, and the particular perils of having less in a country known for its excess.

    Gawky, socially awkward and totally unqualified, his first reaction to this exciting opportunity was panic. But he'd always been drawn to off-beat characters, so maybe his enthusiasm would carry the day. Or, you know, maybe it wouldn't...In Gotta Get Theroux This, Louis takes the reader on a joyous journey through his life and unexpectedly successful career. Nervously accepting the BBC's offer of his own series, he went on to create an award-winning documentary style that has seen him immersed in worlds as diverse as racist US militias and secretive pro-wrestlers, the violent gangs of Johannesburg and extreme drinkers in London.Arguably his biggest challenge was corralling celebrities in his When Louis Met series, with Jimmy Savile proving most elusive. Blindsided when the revelations about Savile came to light, Louis was to reflect again on the nature of evil he had spent decades uncovering.Filled with wry observation, larger-than-life characters, and self-deprecating humour, this is Louis at his insightful and honest best.