We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.

    The emphasis is, instead, on the myriad ways in which the universe presents itself to us--and how, as observers and participants in its processes, we respond to it. "Life, like a dome of many-colored glass," wrote Percy Bysshe Shelley, "stains the white radiance of eternity." The author seeks here to explore the variety that gives life its beauty.Taken from Dyson's recent public lectures--delivered to audiences with no specialized knowledge in hard sciences--the book begins with a consideration of the practical and political questions surrounding biotechnology. As he seeks how best to explain the place of life in the universe, Dyson then moves from the ethical to the purely scientific. The book concludes with an attempt to understand the implications of biology for philosophy and religion.The pieces in this collection touch on numerous disciplines, from astronomy and ecology to neurology and theology, speaking to the lay reader as well as to the scientist. As always, Dyson's view of human nature and behavior is balanced, and his predictions of a world to come serve primarily as a means for thinking about the world as it is today.

    Here and there, we can supplement these meager scraps by the use of biochemical markers or geochemical signatures that add useful information, but, even with such additional help, our reconstructions and our models of descent are often tentative. For the fossil record is, as we have seen, as biased as it is incomplete. But fragmentary, selective, and biased though it is, the fossil record, with all its imperfections, is still a treasure. Though whole chapters are missing, many pages lost, and the earliest pages so damaged as to be, as yet, virtually unreadable, this--the greatest biography of all--is one in whose closing pages we find ourselves.--from OriginsIn Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.Rhodes's accessible and extensively illustrated treatment of the origins narrative describes the nature of the search for prehistoric life, the significance of geologic time, the origin of life, the emergence and spread of flora and fauna, the evolution of primates, and the emergence of modern humans.

    Drawing on an awesome breadth of research, he shows how, long ago, the narrowness of the newly bipedal human female's pelvis and the increasing size of infants' heads precipitated a crisis for the species. Natural selection allowed for the adaptation of the human female to this environmental stress by reconfiguring her hormonal cycles, entraining them with the periodicity of the moon. The results, however, did much more than ensure our existence; they imbued women with the concept of time, and gave them control over sex--a power that males sought to reclaim. And the possibility of achieving immortality through heirs drove men to construct patriarchal cultures that went on to dominate so much of human history.From the nature of courtship to the evolution of language, Shlain's brilliant and wide-ranging exploration stimulates new ways of thinking about very old matters."A masterpiece of ideas and a unique contribution to our understanding of gender and history, sexuality and evolution." -- Jean Houston[Note: includes Reader's Guide]

    H. Freeman and Company.  Visit the  Life, Eighth Edition preview site.  LIFE HAS EVOLVED. . . from its original publication to this dramatically revitalized Eighth Edition. LIFE has always shown students how biology works, offering an engaging and coherent presentation of the fundamentals of biology by describing the landmark experiments that revealed them. This edition builds on those strengths and introduces several innovations.As with previous editions, the Eighth Edition will also be available in three paperback volumes:  • Volume I: The Cell and Heredity, Chapters 1-20  • Volume II: Evolution, Diversity and Ecology, Chapters 1, 21-33, 52-57  • Volume III: Plants and Animals, Chapters 1, 34-51

    In the clearest possible prose it differentiates the firmly established from the speculative and examines the claims of various fields such as string theory to approach a unified theory of everything. In doing so it challenges the orthodox consensus in those branches of cosmology, biology, and neuroscience that have ossified into dogma.Its striking analysis reveals underlying patterns of cooperation, complexification, and convergence that lead to the unique emergence in humans of a self-reflective consciousness that enables us to determine our future evolution.This groundbreaking book is destined to become a classic of scientific thinking.(67 black and white illustrations)

    When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water, turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.' Dr Ben Goldacre is the author of the Bad Science column in the Guardian. His book is about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads.

    Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining.

    A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?

    HOW RISKY IS IT, REALLY?International risk expert David Ropeik takes an in-depth look at our perceptions of risk and explains the hidden factors that make us unnecessarily afraid of relatively small threats and not afraid enough of some really big ones. This read is a comprehensive, accessible, and entertaining mixture of what's been discovered about how and why we fear — too much or too little. It brings into focus the danger of The Perception Gap: when our fears don't match the facts, and we make choices that create additional risks.This book will not decide for you what is really risky and what isn't. That's up to you. HOW RISKY IS IT, REALLY? will tell you how you make those decisions. Understanding how we perceive risk is the first step toward making wiser and healthier choices for ourselves as individuals and for society as a whole.TEST YOUR OWN "RISK RESPONSE" IN DOZENS OF SELF-QUIZZES!

    The result is a wealth of stimulating ideas set among clear explanations drawn from a revelatory decade in biology."—Andrew H. Knoll, author of Life on a Young Planet"Thought-provoking and lucidly written. . . . The Plausibility of Life will help readers understand not just the plausibility of evolution, but its remarkable, inventive powers." —Sean Carroll, author of Endless Forms Most Beautiful: The New Science of Evo Devo“Remarkably lucid and comprehensive, this new theoretical synthesis will . . . shift the grounds for debate in the controversy surrounding organic evolution.”—Booklist (starred review)

    Schein, Sloan Fellows Professor of Management Emeritus and Senior Lecturer, MIT In this astonishing, provocative, and solidly researched book, two Harvard Business School professors synthesize 200 years of thought along with the latest research drawn from the biological and social sciences to propose a new theory, a unified synthesis of human nature. Paul Lawrence and Nitin Nohria have studied the way people behave in that most fascinating arena of human behavior-the workplace-and from their work they produce a book that examines the four separate and distinct emotive drives that guide human behavior and influence the choices people make: the drives to acquire, bond, learn, and defend. They ultimately show that, just as advances in information technology have spurred the New Economy in the last quarter of the twentieth century, current advances in biology will be the key to understanding humans and organizations in the new millennium.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    To shape debates over health care, energy policy, space travel, and other vital issues, ordinary citizens must engage directly with research rather than relying on pundits’ and politicians’ interpretations. Otherwise, fringe opinions that have been discredited in the scientific community can take hold in the public imagination. At the same time, scientists must understand their roles as communicators and ambassadors as well as researchers.Rees not only diagnoses this central problem but also explains how scientists and the general public can deploy a global, long-term perspective to address the new challenges we face. In the process, he reveals critical shortcomings in our current system—for example, the tendency to be overly anxious about minor hazards while underrating the risk of potential catastrophes. Offering a strikingly clear portrait of the future of science, Rees tackles such diverse topics as the human brain, the possibility that humans will colonize other planets, and the existence of extraterrestrial life in order to distinguish between what scientists can hope to discover and what will always lie beyond our grasp.A fresh perspective on science’s significance and potential, From Here to Infinity will inspire and enlighten.