Best of
Genetics

2017

A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution


Jennifer A. Doudna - 2017
    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

DNA: The Story of the Genetic Revolution


James D. Watson - 2017
    Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact--practical, social, and ethical--on our society and our world.

DNA Is Not Destiny: The Remarkable, Completely Misunderstood Relationship between You and Your Genes


Steven J. Heine - 2017
    Yet cultural psychologist Steven J. Heine argues that, in trying to know who we are and where we come from, we’re likely to completely misinterpret what’s “in our DNA.” Heine’s fresh, surprising conclusions about the promise, and limits, of genetic engineering and DNA testing upend conventional thinking and reveal a simple, profound truth: your genes create life—but they do not control it.

Replacing Darwin: The New Origin of Species


Nathaniel T. Jeanson - 2017
    Since Darwin’s time, however, new fields of science have immerged that simply give us better answers to the question of origins. With a Ph.D. in cell and developmental biology from Harvard University, Dr. Nathaniel Jeanson is uniquely qualified to investigate what genetics reveal about origins. The Origins Puzzle Comes Together If the science surrounding origins were a puzzle, Darwin would have had fewer than 15% of the pieces to work with when he developed his theory of evolution. We now have a much greater percentage of the pieces because of modern scientific research. As Dr. Jeanson puts the new pieces together, a whole new picture emerges, giving us a testable, predictive model to explain the origin of species. A New Scientific Revolution Begins Darwin’s theory of evolution may be one of science’s “sacred cows,” but genetics research is proving it wrong. Changing an entrenched narrative, even if it’s wrong, is no easy task. Replacing Darwin asks you to consider the possibility that, based on genetics research, our origins are more easily understood in the context of . . . In the beginning . . . God, with the timeline found in the biblical narrative of Genesis. There is a better answer to the origins debate than what we have been led to believe. Let the revolution begin! About the Author Dr. Nathaniel Jeanson is a scientist and a scholar, trained in one of the most prestigious universities in the world. He earned his B.S. in Molecular Biology and Bioinformatics from the University of Wisconsin-Parkside and his PhD in Cell and Developmental Biology from Harvard University. As an undergraduate, he researched the molecular control of photosynthesis, and his graduate work involved investigating the molecular and physiological control of adult blood stem cells. His findings have been presented at regional and national conferences and have been published in peer-reviewed journals, such as Blood, Nature, and Cell. Since 2009, he has been actively researching the origin of species, both at the Institute for Creation Research and at Answers in Genesis.

The Forgotten Exodus: The Into Africa Theory of Human Evolution


Bruce R. Fenton - 2017
    Each clique of scientists has a part of the story correct, but new evidence shows they are all fundamentally wrong.On the one side, we have academics highlighting the astonishing fossil record of China with multiple sites now producing modern human fossils aged between 80 - 120 thousand years, or older. Several extremely ancient fossil finds in China, including Dali, Maba and Jinniushan, place archaic Homo sapiens in this region up to 260,000 years ago.On the other side, we have scientists pointing to Africa's impressive fossil record with its evidence of potential ancestors going back around 6 million years. The evidence of extreme genetic diversity among Africans and the discovery of 300,000-year-old archaic Homo sapiens fossils in Morocco tends to further support the idea that humans came out from Africa. We can understand why both sides are so sure of their positions, and why the debate continues. While leading academics focussed on their own agendas, they overlooked significant evidence. Between the two poles of Out of Africa and Out of Asia Theory, exists a 'Middle Way'. The Forgotten Exodus: The Into Africa Theory of Human Evolution, reveals that within the known fossil record, the current genetic studies and recent paleoclimate models there is compelling evidence for a superior theory of human origins, representing a paradigm displacement.The Into Africa Theory does not dispute the evidence placing the earliest hominins in Africa.However, it does not agree with the consensus view that Homo sapiens emerged there first and later migrated to Eurasia.The Into Africa Theory recognises the extraordinary evidence for critical stages in our development occurring in East and Southeast Asia. It is abundantly clear that as a new concerted effort to gather and evaluate fossil evidence begins in earnest we see astonishing new discoveries. The Into Africa Theorydisputes the claims of Out of Africa and Out of Asia(or Europe) adherents over the starting point for the migration which populated Eurasia approximately 60,000 years ago and identifies the actual location.Amazing facts that you will encounter:-Homo heidelbergensis was not ancestral to modern humans -Denisovan fossils in Siberia carried DNAfrom Australian Aboriginals-An Indonesian supervolcano brought about the end for multiple hominin species-Climate catastrophe locked humans in Africa from 73,000 to 59,000 years ago-There is no African fossil DNA over 10,000 years in age-While supposedly isolated, Aboriginal Australians interbred with Denisovans 44,000 years agoYou will gain access to a long-forgotten conversation involving the famous evolutionary scientists Allan Wilson and Rebecca Cann, in which they admitted that their data suggested Aboriginal Australians were ancestral to all modern humans.Learn why the appearance of the haplogroups foundational to Eurasians, L3 and CT, had to come from a population incursion rather than an in-situ mutation.Explore the cutting-edge scientific findings of 2016 and 2017 alongside a broad range of anomalies long suppressed or ignored in academic circles.The Forgotten Exodus' author Bruce R. Fenton began his journey towards a new understanding of human origins after an expedition to a mysterious megalithic complex in the Ecuadorian Amazon. The Information Systems professional and lifelong scholar of ancient cultures, found himself tracing the threads of the human story across six continents and through 6,000,000 years of history. You will come away with a unique view of humanity and a sense of excitement for revelations still set to arrive. This book reminds all of us that we have a collective ability to overcome enormous obstacles.

Evolution: The Human Odyssey


Scientific American - 2017
    Each new discovery adds to or revises our story and our understanding of how we came to be the way we are. In this eBook, The Human Odyssey, we explore the evolution of those characteristics that make us human. The first section, “Where We Came From,” looks at our family tree and why some branches survived and not others. Swings in climate are emerging as a factor in what traits succeeded and failed, as we see in “Climate Shocks;” meanwhile in “Human Hybrids,” DNA analyses show that Homo sapiens interbred with other human species, which played a key role in our survival. Section Two, “What Makes Us Special,” examines those traits that separate us from other primates. Recent data indicate that our hairless skin was important to the rise of other human features, and other research is getting closer to illuminating how humans became monogamous, as shown in “The Naked Truth” and “Powers of Two,” respectively. In the final section, “Where We Are Going,” we speculate on the future of human evolution in a world where advances in technology, medicine and other areas protect us from harmful factors like disease, causing some scientists to claim that humans are no longer subject to natural selection and our evolution has ceased. Far from that, in “Still Evolving,” author John Hawks discusses how humans have evolved rapidly over the past 30,000 years, as seen in relatively recent traits like blue eyes or lactose tolerance, why such rapid evolution has been possible and what future generations might look like. Like us, our story will continue to evolve.

Wildwood Academy


Jacqueline Silvester - 2017
    Once there, Nikka quickly falls in love with her bizarre classes, the jaw-dropping scenery and... two very different boys. However, Wildwood Academy has a dark and twisted secret, one that could cost Nikka the one thing she had never imagined she could lose, the one thing that money can’t buy. It is this very thing that Wildwood Academy was created to steal. Nikka can stay and lose everything, or she can risk death and run. ***About the Author*** Jacqueline has had a colourful and dual life thus far; she's lived in a refugee camp in Sweden, a castle in France, a village in Germany, and spent her formative years in between Los Angeles, London and New York. As a result, she speaks four languages. Jacqueline has a Bachelors in English Literature from the University Of Massachusetts, and a Masters in Screenwriting from Royal Holloway, University Of London. After graduating she wrote her first novel and began writing cartoon screenplays. The two years she spent in an arts boarding school in the woods have inspired the particular world described in her debut novel Wunderkids. She lives in London with her husband, her excessive YA collection and a hyper husky named Laika. Wunderkids has been translated into a number of languages and featured in Vogue magazine!

The Postgenomic Condition: Ethics, Justice, and Knowledge after the Genome


Jenny Reardon - 2017
    Drawing on more than a decade of research—in molecular biology labs, commercial startups, governmental agencies, and civic spaces—Reardon demonstrates how the extensive efforts to transform genomics from high tech informatics practiced by a few to meaningful knowledge beneficial to all exposed the limits of long-cherished liberal modes of knowing and governing life. Those in the American South challenged the value of being included in genomics when no hospital served their community.  Ethicists and lawyers charged with overseeing Scottish DNA and data questioned how to develop a system of ownership for these resources when their capacity to create things of value—new personalized treatments—remained largely unrealized. Molecular biologists who pioneered genomics asked whether their practices of thinking could survive the deluge of data produced by the growing power of sequencing machines. While the media is filled with grand visions of precision medicine, The Postgenomic Condition shares these actual challenges of the scientists, entrepreneurs, policy makers, bioethicists, lawyers, and patient advocates who sought to leverage liberal democratic practices to render genomic data a new source of meaning and value for interpreting and caring for life. It brings into rich empirical focus the resulting hard on-the-ground questions about how to know and live on a depleted but data-rich, interconnected yet fractured planet, where technoscience garners significant resources, but deeper questions of knowledge and justice urgently demand attention.

The Aryan Invasion Myth: How 21st Century Science Debunks 19th Century Indology


A.L. Chavda - 2017
    These Indo-Aryans were of European origin (hence white-skinned), and spoke Vedic Sanskrit. They destroyed the indigenous Dravidian civilization, subjugated the natives, and forced them to migrate to India's South. First propounded by Max Müller, the AIT has been regarded as self-evident since the 19th century. The interrelated fields of population genetics, comparative genetics, archaeogenetics, genomics, and genotyping have made it possible to gain an unprecedented insight into the nature of human genetic diversity. These advances in genetics, as well as new archaeological investigations, are transforming our understanding of India'a ancient history. There is now overwhelming scientific evidence that proves that the Aryan Invasion Theory is a myth. It is fiction. It belongs in the Big League of unscientific theories (which some still believe in), alongside creationism, anti-evolutionism, the myth of Noah’s ark, and flat earth theory. Nevertheless, India's history textbooks continue to teach antiquated and unscientific 19th century concepts and ideas well into the 21st century. Indian academia's entrenched ancien régime has a vested interest in ensuring that the Aryan Invasion Theory remains the dominant narrative in India. Read on to find out why.

Life on Ice: A History of New Uses for Cold Blood


Joanna Radin - 2017
    These samples were believed to embody potentially invaluable biological information about genetic ancestry, evolution, microbes, and much more. Today, they persist in freezers as part of a global tissue-based infrastructure. In Life on Ice, Joanna Radin examines how and why these frozen blood samples shaped the practice known as biobanking.   The Cold War projects Radin tracks were meant to form an enduring total archive of indigenous blood before it was altered by the polluting forces of modernity. Freezing allowed that blood to act as a time-traveling resource. Radin explores the unique cultural and technical circumstances that created and gave momentum to the phenomenon of life on ice and shows how these preserved blood samples served as the building blocks for biomedicine at the dawn of the genomic age. In an era of vigorous ethical, legal, and cultural debates about genetic privacy and identity, Life on Ice reveals the larger picture—how we got here and the promises and problems involved with finding new uses for cold human blood samples.

Lewin's GENES XII (Lewins Genes)


Jocelyn E. Krebs - 2017
    Leading scientists provide revisions and updates in their individual field of study offering readers current data and information on the rapidly changing subjects in molecular biology.