Embracing the unifying themes of 'symptom endophenotypes', dimensions of psychopathology that cut across syndromes, and 'symptoms and circuits', every aspect of the text has been updated to the frontiers of current knowledge, with the clarity of explanation and illustration that only Dr Stahl can bring. Integrating much of the basic neuroscience into the clinical chapters, and with major additions in the areas of psychosis, antipsychotics, antidepressants, impulsivity, compulsivity and addiction, this is the single most readily readable source of information on disease and drug mechanisms. This remains the essential text for all students and professionals in mental health seeking to understand and utilize current therapeutics, and to anticipate the future for novel medications.

    Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    Full of extraordinary facts and astonishing stories, The Body: A Guide for Occupants is a brilliant, often very funny attempt to understand the miracle of our physical and neurological make up.A wonderful successor to A Short History of Nearly Everything, this book will have you marvelling at the form you occupy, and celebrating the genius of your existence, time and time again.

    In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.

    It strikes a balance between theory and application by incorporating real-world examples; helping students visualize the three-dimensional atomic and molecular structures that are the basis of chemical activity; and developing problem-solving and critical thinking skills. Although the fifth edition incorporates many new features, such as macro to micro artwork, six new animations correlated to the text, and the addition of new hand-sketched worked examples, General Chemistry is still 200 to 300 pages shorter and much less expensive than other two-semester textbooks. Dr. Chang's concise-but-thorough approach will appeal to efficiency-minded instructors and value-conscious students.

     Unlike other hormone books on the market, Female Brain Gone Insane is less focused on physiological changes such as bone loss and weight gain and instead tackles the legitimate panic and distress women feel as they experience symptoms associated with emotional and intellectual turmoil, including mood swings, loss of concentration and/or memory, and mental acuteness, to name a few. Women who have asked 'Why do I feel like I am losing it? 'How can I cope with the emotional changes I am experiencing?' and 'Will I ever feel like myself again?' will find real and compassionate help in this emergency guidebook. What's even more unique, is the author's contention that changes in the brain that affect a woman's mood, memory, concentration, and acuteness may not always be a hormone imbalance caused by menopause or other female-specific issues, as doctors often misdiagnose, but imbalances induced by the stress and anxiety levels associated with our fast-paced lifestyles that affect us at a deeper level. Bottom line, the key to a woman's well being is balanced brain chemistry, and Female Brain Gone Insane offers customizable solutions for every woman. Without lumping all women into one category, Female Brain Gone Insane helps each woman identify the symptoms of her particular emotional and psychological problems---be they depression, panic attacks, memory loss, or even acting out of character, and then offers support, information, and treatment so that she can rebalance herself.  The core of the plan is to use bio-identical hormones (using the right hormone at the right time) and supplements carefully chosen to manipulate brain chemistry so that the body is happy again! Women will be liberated from their emotional turmoil with step-by-step, tailor-made rescue prescriptions based on the author's thriving practice of more than 3,000 satisfied patients. No more misdiagnoses or 'Band-aid' treatments such as antidepressants, birth-control pills, or even unnecessary surgeriesUnique philosophy, accompanied with a combination of bio-identical hormones, nutritional supplements, good food, including targeted amino acid therapy, and lifestyle changes allows women to truly manipulate and support their brain chemistry  Readers learn the basic science behind the intricate dance between their hormones and brain chemistry and are then encouraged to respect and identify their own emotional and physical symptomsIdentifies the underlying causes of emotional symptoms and addresses women's unique bio-chemical composition with a new and unconventional approach to integrating bio-identical hormones, targeted amino acid therapy, and other nutritional supplements.

    This thorough revision provides a survey by groups, emphasizing adaptive morphology and physiology, while covering anatomical ground plans and basic developmental patterns. New co-author Richard Fox brings to the revision his expertise as an ecologist, offering a good balance to Ruppert's background as a functional morphologist. Rich illustrations and extensive citations make the book extremely valuable as a teaching tool and reference source.

    With a name like Jackson (the twentieth most common American surname), she knew she must have more relatives and more family history out there, somewhere. Her first visit to the Boulder Genealogy Society brought her more questions than answers . . . but it also gave her a tantalizing peek into the fascinating (and enormous) community of family-tree huggers and after-hours Alex Haleys. In Shaking the Family Tree, Jackson dives headfirst into her family gene pool: flying cross-country to locate an ancient family graveyard, embarking on a weeklong genealogy Caribbean cruise, and even submitting her DNA for testing to try to find her Jacksons. And in the process of researching her own family lore (Who was Bullwhip Jackson?) she meets legions of other genealogy buffs who are as interesting as they are driven—from the boy who saved his allowance so he could order his great-grandfather’s death certificate to the woman who spends her free time documenting the cemeteries of Colorado ghost towns. Through Jackson’s research she connects with distant relatives, traces her roots back more than 250 years and in the process comes to discover—genetically, historically, and emotionally—the true meaning of “family” for herself.

    With plenty of engaging material, practice questions, and practical ideas, this updated edition contains everything your students need to succeed in Cambridge IGCSE biology.

    Through applications to criminal investigations, clear explanations of the techniques, and the abilities and limitations of modern crime labs, Criminalistics covers the comprehensive realm of forensics. The book strives to make the technology of the modern crime laboratory clear to the non-scientist. Combining case stories with applicable technology, Criminalistics captures the excitement of forensic science investigations. Familiarizes readers with the most current technologies in forensic analysis. KEY Aims at making the subject of forensic science comprehensible to a wide variety of readers who are planning on being aligned with the forensic science profession.

    Each case includes an extended discussion, definition of terms, clinical pearls, and USMLE format review questions. This interactive learning system helps you to understand essential concepts instead of memorizing facts.

    In clear, lively, warm prose, this edition continues the title's integration of gender, culture, and ethnicity. By the end, readers will learn how to interpret research and to address and resolve controversies. MyPsychLab is an integral part of the Wade/Tavris/Garry program. Engaging activities and assessments provide a teaching and learning system that helps students think like a psychologist. With MyPsychLab, students can watch videos on psychological research and applications, participate in virtual classic experiments, and develop critical thinking skills through writing. "Invitation to Psychology, "5/e is available in a new DSM-5 Updated edition. To learn more, click here. This title is available in a variety of formats - digital and print. Pearson offers its titles on the devices students love through Pearson's MyLab products, CourseSmart, Amazon, and more.

    The book guides genealogists in understanding various tests and determining what DNA segments came from which ancestor. The book explains how DNA testing helps when written records stop and discusses how testing proves or disprove oral family history. Learn which tests help adoptees; understand why you resemble your relatives and how testing can connect you with cousins you never knew. Discover how to encourage potential cousins to test and learn guidelines for becoming a project administrator, genetic genealogy speaker or facilitator for your genealogical society’s DNA interest group. A Genetic Genealogy Handbook: The Basics and Beyond helps experienced and fledgling researchers become genetic genealogists able to use DNA testing to resolve genealogical roadblocks."

    The Cell: a Molecular Approach meets this challenge by providing students with not only the current information, but also with an introduction to the experimental nature of contemporary research. Designed for use in introductory cell biology courses, The Cell presents current, comprehensive science in a readable and cohesive text that students can master in the course of one semester. The new third edition of The Cell retains the organization, themes, and special features of earlier editions, but is updated to reflect scientific advances since publication of the second edition, including progress in genome sequencing, advances in understanding transcriptional regulation and mRNA processing, use of DNA microarrays in global studies of gene expression and cancer diagnostics, advances in nuclear transport and protein trafficking, progress in understanding the regulation of programmed cell death, potential medical applications of embryonic cells, and development of oncogene-targeted treatments. Key Experimental boxes in each chapter describe seminal experiments in modern cell biology, showing the detail and background to give students a sense of doing science. Molecular Medicine boxes relate basic science to clinical practice or potential and show the excitement of molecular discovery and solutions to disease. Chapter summaries are organized in outline form corresponding to the major sections and subsections of each chapter. This section-by-section format is coupled with a list of the key terms introduced in eachsection, providing a succinct but comprehensive review of the material. The full-color art program is both pedagogically and scientifically outstanding. In addition, each chapter includes a brief chapter outline, boldfaced key terms (also defined in the glossary), and many new chapter-end questions with answers in the back of the book. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. The book can be bundled for purchase with a special edition of Molecules, Cells, and Genes, a CD-ROM keyed to the textbook and combining the essential features of a Study Guide and Problems book.

    In this Very Short Introduction, eminent biologist and popular science writer Dorothy Crawford offers a fascinating portrait of these infinitesimally small but often highly dangerous creatures. Crawford first relates how viruses were discovered and she unravels the intricate structures of tiny parasites that are by far the most abundant life forms on the planet. Analyzing the threat of viral infections, Crawford recounts stories of renowned killer viruses such as Ebola and rabies as well as the less known bat-borne Nipah and Hendra viruses. She identifies wild animals as the source of the most recent pandemics, detailing the reasons behind the present increase in potentially fatal infections, and evaluating the evidence that suggests that long term viruses can eventually lead to cancer. Finally, Crawford looks to the future to ask whether we can ever live in harmony with viruses, and considers ways to prevent the emergence of new and devastating viruses.