In this now-classic study, Michael Bliss unearths a wealth of material, ranging from scientists& unpublished memoirs to the confidential appraisals of insulin by members of the Nobel Committee. He also resolves a longstanding controversy dating to the awarding of the Nobel to F. G. Banting and J. J. R. Macleod for their work on insulin: because each insisted on sharing the credit with an additional associate, medical opinion was intensely divided over the allotment of credit for the discovery. Bliss also offers a wealth of new detail on such subjects as the treatment of diabetes before insulin and the life-and-death struggle to manufacture it.Bliss;s excellent account of the insulin story is a rare dissection of the anatomy of scientific discovery, and serves as a model of how rigorous historical method can correct the myths and legends sometimes perpetrated in the scientific literature.

    Hill provides an incisive analysis of everyday language to reveal the underlying racist stereotypes that continue to circulate in American culture.* Provides a detailed background on the theory of race and racism* Reveals how racializing discourse--talk and text that produces and reproduces ideas about races and assigns people to them--facilitates a victim-blaming logic* Integrates a broad and interdisciplinary range of literature, from sociology, social psychology, justice studies, critical legal studies, philosophy, literature, and other disciplines that have studied racism, as well as material from anthropology and sociolinguistics* Part of the "Blackwell Studies in Discourse and Culture Series"

    The crime resonated deeply with America's bitter history of violence against minorities, and something about Matt Shepard himself struck a chord with people across the nation. Although the details of the tragedy are familiar to most people, the complex and ever-shifting context of the killing is not. Losing Matt Shepard explores why the murder still haunts us--and why it should.Beth Loffreda is uniquely qualified to write this account. As a professor new to the state and a straight faculty advisor to the campus Lesbian Gay Bisexual Transgender Association, she is both an insider and outsider to the events. She draws upon her own penetrating observations as well as dozens of interviews with students, townspeople, police officers, journalists, state politicians, activists, and gay and lesbian residents to make visible the knot of forces tied together by the fate of this young man.This book shows how the politics of sexuality--perhaps now the most divisive issue in America's culture wars--unfolds in a remote and sparsely populated area of the country. Loffreda brilliantly captures daily life since October 1998 in Laramie, Wyoming--a community in a rural, poor, conservative, and breathtakingly beautiful state without a single gay bar or bookstore. Rather than focus only on Matt Shepard, she presents a full range of characters, including a panoply of locals (both gay and straight), the national gay activists who quickly descended on Laramie, the indefatigable homicide investigators, the often unreflective journalists of the national media, and even a cameo appearance by Peter, Paul, and Mary.Loffreda courses through a wide ambit of events: from the attempts by students and townspeople to rise above the anti-gay theatrics of defrocked minister Fred Phelps to the spontaneous, grassroots support for Matt at the university's homecoming parade, from the emotionally charged town council discussions about bias crimes legislation to the tireless efforts of the investigators to trace that grim night's trail of evidence. Charting these and many other events, Losing Matt Shepard not only recounts the typical responses to Matt's death but also the surprising stories of those whose lives were transformed but ignored in the media frenzy.

    Broch's characters—an apathetic man who can barely remember his own name (Broch mostly refers to him as A.); a high-school teacher and his lover who return from the brink of a suicide pact to carry on a dishonest relationship; Zerline, the lady's maid who enslaves her mistresses, prostitutes the young country girl Melitta to gentleman A., and metes out her own justice against the "empty wickedness" of her betters—are trapped in their indifference, prisoners of a sort of "wakeful somnolence." These men and women may mention the "imbecile Hitler," yet they prefer a nap or sexual encounter to any social action. In Broch's mind this kind of ethical perversity and political apathy paved the way for Nazism.Broch believed that writing can purify, and by revealing Germany's underlying guilt he hoped to purge indifference from his own and future generations. In The Guiltless, Broch captures how apathy and ennui?very human failings—evolve into something dehumanizing and dangerous.About the Translator:Ralph Manheim translated Hourglass by Danilo Kis and numerous works by Gunter Grass, including The Tin Drum. He has edited and translated novels and plays by Bertolt Brecht, Hermann Hesse, and Erich Maria Remarque.

    Three days later, her body, badly bruised and waterlogged, was found floating in the shallow waters of the Hudson River just a few feet from the Jersey shore. Her story, parlayed into a long celebrated unsolved mystery, became grist for penny presses, social reformers, and politicians alike, and an impetus for popular literature, including Edgar Allan Poe's pioneering detective story "The Mystery of Marie Roget."In The Mysterious Death of Mary Rogers, historian Amy Gilman Srebnick brilliantly recaptures the story of Mary Rogers, showing how Rogers represented an emerging class of women who took advantage of the greater economic and sexual opportunities available to them in urban America, and how her death became a touchstone for the voicing of mid-nineteenth century concerns over sexual license, the changing roles of women, law and order, and abortion. Rogers's death, first thought due to a murderous gang of rapists and later tacitly understood to be the result of an ill-performed abortion, quickly became a source of popular entertainment, a topic of political debate, and an inspiration to public policy. The incident and the city's response to it provides a fascinating window into the urban culture and consciousness of the mid-1800s. Indeed, in Rogers's name, and as a direct result of her death, two important pieces of legislation were passed in 1845: the New York City Police Reform Act which effectively modernized the city's system of policing, and the New York State law criminalizing abortion.The Mysterious Death of Mary Rogers tells a story of a death, but more importantly it also tells the story of a life--that of Mary Rogers--and of the complex urban social world of which she was a part. Like the city in which she lived, Mary Rogers was a source of wonder, mystery, and fear, provoking desire, and inspiring narrative.

    In such a scenario, it makes sense to focus on the most identifiable and urgent problems, right? Actually, it doesn't. In his classic essay "The Usefulness of Useless Knowledge," Abraham Flexner, the founding director of the Institute for Advanced Study in Princeton and the man who helped bring Albert Einstein to the United States, describes a great paradox of scientific research. The search for answers to deep questions, motivated solely by curiosity and without concern for applications, often leads not only to the greatest scientific discoveries but also to the most revolutionary technological breakthroughs. In short, no quantum mechanics, no computer chips.This brief book includes Flexner's timeless 1939 essay alongside a new companion essay by Robbert Dijkgraaf, the Institute's current director, in which he shows that Flexner's defense of the value of "the unobstructed pursuit of useless knowledge" may be even more relevant today than it was in the early twentieth century. Dijkgraaf describes how basic research has led to major transformations in the past century and explains why it is an essential precondition of innovation and the first step in social and cultural change. He makes the case that society can achieve deeper understanding and practical progress today and tomorrow only by truly valuing and substantially funding the curiosity-driven "pursuit of useless knowledge" in both the sciences and the humanities.

    The adjective 'medieval' has become a synonym for brutality and uncivilized behavior. Yet without the work of medieval scholars there could have been no Galileo, no Newton and no Scientific Revolution. In God's Philosophers, James Hannam debunks many of the myths about the Middle Ages, showing that medieval people did not think the earth is flat, nor did Columbus 'prove' that it is a sphere; the Inquisition burnt nobody for their science nor was Copernicus afraid of persecution; no Pope tried to ban human dissection or the number zero. God's Philosophers is a celebration of the forgotten scientific achievements of the Middle Ages - advances which were often made thanks to, rather than in spite of, the influence of Christianity and Islam. Decisive progress was also made in technology: spectacles and the mechanical clock, for instance, were both invented in thirteenth-century Europe. Charting an epic journey through six centuries of history, God's Philosophers brings back to light the discoveries of neglected geniuses like John Buridan, Nicole Oresme and Thomas Bradwardine, as well as putting into context the contributions of more familiar figures like Roger Bacon, William of Ockham and Saint Thomas Aquinas.

    In the United States, fat is seen as repulsive, funny, ugly, unclean, obscene, and above all as something to lose. Bodies Out of Bounds challenges these dominant perceptions by examining social representations of the fat body. The contributors to this collection show that what counts as fat and how it is valued are far from universal; the variety of meanings attributed to body size in other times and places demonstrates that perceptions of corpulence are infused with cultural, historical, political, and economic biases. The exceptionally rich and engaging essays collected in this volume question discursive constructions of fatness while analyzing the politics and power of corpulence and addressing the absence of fat people in media representations of the body.The essays are widely interdisciplinary; they explore their subject with insight, originality, and humor. The contributors examine the intersections of fat with ethnicity, race, queerness, class, and minority cultures, as well as with historical variations in the signification of fat. They also consider ways in which "objective" medical and psychological discourses about fat people and food hide larger agendas. By illustrating how fat is a malleable construct that can be used to serve dominant economic and cultural interests, Bodies Out of Bounds stakes new claims for those whose body size does not adhere to society's confining standards.

    Warnings that depressive disorder is a leading cause of worldwide disability have been accompanied by a massive upsurge in the consumption of antidepressant medication, widespread screening for depression in clinics and schools, and a push to diagnose depression early, on the basis of just a few symptoms, in order to prevent more severe conditions from developing.In The Loss of Sadness, Allan V. Horwitz and Jerome C. Wakefield argue that, while depressive disorder certainly exists and can be a devastating condition warranting medical attention, the apparent epidemic in fact reflects the way the psychiatric profession has understood and reclassified normal human sadness as largely an abnormal experience. With the 1980 publication of the landmark third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), mental health professionals began diagnosing depression based on symptoms—such as depressed mood, loss of appetite, and fatigue—that lasted for at least two weeks. This system is fundamentally flawed, the authors maintain, because it fails to take into account the context in which the symptoms occur. They stress the importance of distinguishing between abnormal reactions due to internal dysfunction and normal sadness brought on by external circumstances. Under the current DSM classification system, however, this distinction is impossible to make, so the expected emotional distress caused by upsetting events—for example, the loss of a job or the end of a relationship—could lead to a mistaken diagnosis of depressive disorder. Indeed, it is this very mistake that lies at the root of the presumed epidemic of major depression in our midst.

    Ross A. Slotten signed more death certificates in Chicago—and, by inference, the state of Illinois—than anyone else. As a family physician, he was trained to care for patients from birth to death, but when he completed his residency in 1984, he had no idea that many of his future patients would be cut down in the prime of their lives. Among those patients were friends, colleagues, and lovers, shunned by most of the medical community because they were gay and HIV positive. Slotten wasn’t an infectious disease specialist, but because of his unique position as both a gay man and a young physician, he became an unlikely pioneer, swept up in one of the worst epidemics in modern history.Plague Years is an unprecedented first-person account of that epidemic, spanning not just the city of Chicago but four continents as well. Slotten provides an intimate yet comprehensive view of the disease’s spread alongside heartfelt portraits of his patients and his own conflicted feelings as a medical professional, drawn from more than thirty years of personal notebooks. In telling the story of someone who was as much a potential patient as a doctor, Plague Years sheds light on the darkest hours in the history of the LGBT community in ways that no previous medical memoir has.

    Merry Wiesner has updated and expanded her prize-winning study; she has added new sections on topics such as sexuality, masculinity, the impact of colonialism, and women's role as consumers. Other themes investigated include the female life cycle, literacy, women's economic role, artistic creation, female piety--and witchcraft--and the relationship between gender and power. Accessible, engrossing, and lively, this book will be of central importance for those interested in gender history, early modern Europe, and comparative history.

    He drops out of architecture school and decides to travel to Vals in the Swiss Alps, home to a thermal springs complex located deep inside a mountain. The complex, designed by architect Peter Zumthor, had been the subject of Pierre's thesis. The mountain holds many mysteries; it was said to have a mouth that periodically swallowed people up. Pierre, sketchbook in hand, is drawn to the enigmatic powers of the mountain and its springs, and attempts to uncover the truth behind them in the secret rooms he discovers deep within the complex. But he finds his match in a man named Valeret who is similarly obsessed, and who'd like nothing more than to eliminate his competitor.Gorgeously illustrated, Swimming in Darkness is an intriguing, noirish graphic novel about uncovering the powerful secrets of the natural world.

    . . . And we are trying to do what’s right even when Donald Trump won’t.”—An anonymous senior administrative official in an op-ed published in a New York Times op-ed, September 5, 2018 Every president faces criticism and caricature. Donald Trump, however, is unique in that he is routinely characterized in ways more suitable for a toddler. What’s more, it is not just Democrats, pundits, or protestors who compare the president to a child; Trump’s staffers, subordinates, and allies on Capitol Hill also describe Trump like a small, badly behaved preschooler.            In April 2017, Daniel W. Drezner began curating every example he could find of a Trump ally describing the president like a toddler. So far, he’s collected more than one thousand tweets—a rate of more than one a day. In The Toddler-in-Chief, Drezner draws on these examples to take readers through the different dimensions of Trump’s infantile behavior, from temper tantrums to poor impulse control to the possibility that the President has had too much screen time. How much damage can really be done by a giant man-baby? Quite a lot, Drezner argues, due to the winnowing away of presidential checks and balances over the past fifty years. In these pages, Drezner follows his theme—the specific ways in which sharing some of the traits of a toddler makes a person ill-suited to the presidency—to show the lasting, deleterious impact the Trump administration will have on American foreign policy and democracy.            The “adults in the room” may not be able to rein in Trump’s toddler-like behavior, but, with the 2020 election fast approaching, the American people can think about whether they want the most powerful office turned into a poorly run political day care facility. Drezner exhorts us to elect a commander-in-chief, not a toddler-in-chief. And along the way, he shows how we must rethink the terrifying powers we have given the presidency.

    Children have trouble waiting for anything. (“Are we there yet?”) Boredom is often connected to our sense of time passing (or not passing). As people grow older, time seems to speed up, the years flitting by without a pause. How does our sense of time come about? In Felt Time, Marc Wittmann explores the riddle of subjective time, explaining our perception of time—whether moment by moment, or in terms of life as a whole. Drawing on the latest insights from psychology and neuroscience, Wittmann offers a new answer to the question of how we experience time.Wittmann explains, among other things, how we choose between savoring the moment and deferring gratification; why impulsive people are bored easily, and why their boredom is often a matter of time; whether each person possesses a personal speed, a particular brain rhythm distinguishing quick people from slow people; and why the feeling of duration can serve as an “error signal,” letting us know when it is taking too long for dinner to be ready or for the bus to come. He considers the practice of mindfulness, and whether it can reduce the speed of life and help us gain more time, and he describes how, as we grow older, subjective time accelerates as routine increases; a fulfilled and varied life is a long life. Evidence shows that bodily processes—especially the heartbeat—underlie our feeling of time and act as an internal clock for our sense of time. And Wittmann points to recent research that connects time to consciousness; ongoing studies of time consciousness, he tells us, will help us to understand the conscious self.

    The selections in this anthology show how Orwell developed as writer and as thinker; inevitably, too, they reflect and illuminate the history of the time of troubles in which he lived and worked. “A magnificent tribute to the probity, consistency and insight of Orwell’s topical writings” (Alfred Kazin). Introduction by Richard H. Rovere.