An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    And you'll also learn the "rules of the game" - the forces that drive those particles and the ways in which they interact - that underlie the workings of the universe.The lectures have been designed to be enriching for everyone, regardless of scientific background or mathematical ability. Virtually all you'll need as you enter this fascinating world are your curiosity, common sense, and, as Professor Pollock notes, "an open mind for the occasional quantum weirdness." As you move through the lectures, you'll also gain a knowledge of how those particles fit into perhaps the greatest scientific theory of all time: the Standard Model of particle physics; a grasp of key terms like "gauge symmetry," "quantum chromodynamics," and "unified quantum field Theory;" and an appreciation of how particle physics fits in with other branches of physics - including cosmology and quantum mechanics - to create our overall understanding of nature.

    Dieting is the problem. A society that rejects anyone whose body shape or size doesn’t match an impossible ideal is the problem. A medical establishment that equates "thin" with "healthy" is the problem. Health at Every Size: The Surprising Truth About Your Weight by Linda Bacon, PhD, presents a well-researched, healthy-living manual that debunks the weight myths and translates the latest science into practical advice to help readers forever end their battle with weight.

    Food psychologist Brian Wansink revolutionizes our awareness of how much, what, and why we’re eating—often without realizing it. His findings will astound you. • Can the size of your plate really influence your appetite?• Why do you eat more when you dine with friends?• What “hidden persuaders” are used by restaurants and supermarkets to get us to overeat?• How does music or the color of the room influence how much—and how fast—we eat?• How can we “mindlessly” lose—instead of gain—up to twenty pounds in the coming year? Starting today, you can make more mindful, enjoyable, and healthy choices at the dinner table, in the supermarket, at the office—wherever you satisfy your appetite.

    Why We Eat (Too Much), combines case studies from his practice and the new science of metabolism to illuminate how our appetite really works.Debunking the great myths of the body, and systematically explaining why dieting is counter-productive, this unflinching book investigates every aspect of nutrition. From the difference between good and bad fats to the impact of genes and genetic mutation on our weight and what happens to our hormones long after a diet ends, Dr Jenkinson explores the fields of agriculture, pharma, anthropology and medicine to uncover the truth behind our bad food habits and the escalating obesity crisis.Joanna Blythman, author of Swallow This'Fascinating science' ITV 'Highly persuasive ... a radical approach to weight loss' Sunday Times'A compelling look at the science of appetite and metabolism' Vogue___________________________________________________________A practical, accessible guide to understanding the diet myth and the secret to lasting weight loss.

    Gilbert WelchRead Overdiagnosed: Making People Sick in the Pursuit of Health PDF from Beacon Press,H. Gilbert WelchDownload H. Gilbert Welch's PDF E-book Overdiagnosed: Making People Sick in the Pursuit of Health

    There are good reasons that language fascinates us so. It not only defines humans as a species, placing us head and shoulders above even the most proficient animal communicators, but it also beguiles us with its endless mysteries. For example: * How did different languages come to be? * Why isn’t there just a single language? * How does a language change, and when it does, is that change indicative of decay or growth? * How does a language become extinct? Dr. John McWhorter, one of America’s leading linguists and a frequent commentator on network television and National Public Radio, addresses these and other questions as he takes you on an in-depth, 36-lecture tour of the development of human language, showing how a single tongue spoken 150,000 years ago has evolved into the estimated 6,000 languages used around the world today.An accomplished scholar, Professor McWhorter is also a skilled popularizer, whose book The Power of Babel was called "startling, provocative, and remarkably entertaining," by the San Diego Union-Tribune.The London Times called him "a born teacher." And Steven Pinker, best known as the author of The Language Instinct, offered this praise for the book: "McWhorter’s arguments are sharply reasoned, refreshingly honest, and thoroughly original."Course Lecture Titles1. What Is Language? 2. When Language Began 3. How Language Changes—Sound Change 4. How Language Changes—Building New Material 5. How Language Changes—Meaning and Order 6. How Language Changes—Many Directions 7. How Language Changes—Modern English 8. Language Families—Indo-European 9. Language Families—Tracing Indo-European 10. Language Families—Diversity of Structures 11. Language Families—Clues to the Past 12. The Case Against the World’s First Language 13. The Case For the World’s First Language 14. Dialects—Subspecies of Species 15. Dialects—Where Do You Draw the Line? 16. Dialects—Two Tongues in One Mouth 17. Dialects—The Standard as Token of the Past 18. Dialects—Spoken Style, Written Style 19. Dialects—The Fallacy of Blackboard Grammar 20. Language Mixture—Words 21. Language Mixture—Grammar 22. Language Mixture—Language Areas 23. Language Develops Beyond the Call of Duty 24. Language Interrupted 25. A New Perspective on the Story of English 26. Does Culture Drive Language Change? 27. Language Starts Over—Pidgins 28. Language Starts Over—Creoles I 29. Language Starts Over—Creoles II 30. Language Starts Over—Signs of the New 31. Language Starts Over—The Creole Continuum 32. What Is Black English? 33. Language Death—The Problem 34. Language Death—Prognosis 35. Artificial Languages 36. Finale—Master Class

    Lions, rhino, and buffalo roam the plains on either side. But I haven’t come to Kenya to spot wildlife. I’ve come to run.”   Whether running is your recreation, your religion, or just a spectator sport, Adharanand Finn’s incredible journey to the elite training camps of Kenya will captivate and inspire you. Part travelogue, part memoir, this mesmerizing quest to uncover the secrets of the world’s greatest runners—and put them to the test—combines practical advice, a fresh look at barefoot running, and hard-won spiritual insights.   As a boy growing up in the English countryside, Adharanand Finn was a natural runner. While other kids struggled, he breezed through schoolyard races, imagining he was one of his heroes: the Kenyan long-distance runners exploding into prominence as Olympic and world champions. But as he grew up, pursued a career in journalism, married and had children, those childhood dreams slipped away—until suddenly, in his mid-thirties, Finn realized he might have only one chance left to see how far his talents could take him.   Uprooting his family of five, including three small children, Finn traveled to Iten, a small, chaotic town in the Rift Valley province of Kenya—a mecca for long-distance runners thanks to its high altitude, endless running paths, and some of the top training schools in the world. Finn would run side by side with Olympic champions, young hopefuls, and barefoot schoolchildren . . . not to mention the exotic—and sometimes dangerous—wildlife for which Kenya is famous.   Here, too, he would meet a cast of colorful characters, including his unflappable guide, Godfrey Kiprotich, a former half marathon champion; Christopher Cheboiboch, one of the fastest men ever to run the New York City Marathon; and Japhet, a poor, bucktoothed boy with unsuspected reservoirs of courage and raw speed. Amid the daily challenges of training and of raising a family abroad, Finn would learn invaluable lessons about running—and about life.  Running with the Kenyans is more than one man’s pursuit of a lifelong dream. It’s a fascinating portrait of a magical country—and an extraordinary people seemingly born to run.

    Charting the most cutting-edge scientific breakthroughs, and marshalling his decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood and energy levels, regulate hormones, prevent cancer, Alzheimer's and diabetes, slow the effects of aging, and increase longevity. He also provides actionable steps towards getting a better night's sleep every night.

    Peter D'Adamo and Catherine Whitney reveal the simple secret to healthy, vigorous, and disease-free living: basing your diet on your blood type. If you've ever suspected that not everyone should eat the same thing or do the same exercise, you're right. In fact, what foods we absorb well and how our bodies handle stress differ with each blood type. Your blood type reflects your internal chemistry. It is the key that unlocks the mysteries of disease, longevity, fitness, and emotional strength. It determines your susceptibility to illness, the foods you should eat, and ways to avoid the most troubling health problems. In Eat Right 4 Your Type, Dr. D'Adamo draws on over fifteen years of research to reveal: - Which foods, spices, teas, and condiments help maintain optimal health and ideal weight - Which vitamins and supplements to emphasize or avoid - Whether your stress is relieved better through aerobics or meditation - Whether you should walk, swim or play tennis or golf as your mode of exercise - How knowing your blood type can help you avoid many common viruses and infections and fight back against life-threatening diseases - How to slow down the aging process by avoiding factors that cause rapid cell deterioration Whether your blood type is O, A, B, or AB, Eat Right 4 Your Type will help you design a total health program that's perfect for you. MORE THAN 7 MILLION COPIES SOLD WORLDWIDE!

    But what happens when we hit a wall and weight loss stalls, energy flags, or we're tired of restricted eating? We're not cavemen anymore, so why should we follow a strict caveman diet? In YOUR PERSONAL PALEO CODE, Chris Kresser uses the Paleo diet as a baseline from which you can tailor the ideal three-step program-Reset, Rebuild, Revive-to fit your lifestyle, body type, genetic blueprint, and individual needs. Kresser helps further personalize your prescription for specific health conditions, from heart disease and high blood pressure to thyroid disorders and digestive problems. Along with a 7-day meal plan and delectable, nutritious recipes, YOUR PERSONAL PALEO CODE offers natural solutions and an avalanche of groundbreaking advice on how to restore a healthy gut and immune system; how to eliminate toxins; which fats to eat liberally; how to choose the healthiest proteins; and much more. Best of all, you only have to follow the program 80% of the time; there's room to indulge in moderation while still experiencing dramatic results. Based on cutting-edge scientific research, YOUR PERSONAL PALEO CODE is designed to be flexible and user-friendly, with helpful charts, quizzes, and effective action steps to help you lose weight, reverse disease, and stay fit and healthy for life.

    And they'll guide you on making intelligent and educated decisions about food. They may be bitches, but they are skinny bitches. And you'll be one too--after you get with the program and start eating right.

    Start your day with her Fab Four Smoothies, including a Strawberry Shortcake Smoothie and a Mango Kale Madness Smoothie, which pack protein, fat, fiber, and carbs to balance your blood sugar and keep you full and happy. After breakfast, you’ll thrive with her Fab Four recipes, including Turkey-Stuffed Delicata Squash, Spicy Salmon Nori Burritos, and Anti-Inflammatory Detox Salad, which include the Fab Four food groups—protein, fat, fiber, and greens—that play a role in day-long satiety. Kelly also teaches you how to elongate your blood sugar curve to stay full and happy, and make yourself insulin aware.Kelly has studied the science behind familiar diets to understand how they trigger the body to lose pounds—and why they aren’t sustainable. Instead, she offers a better choice: her four-step Food Freedom program that helps you find your wellness balance between eating enough and deciding how you feel. Once you find your balance, you will lose weight, lose fat, increase lean muscle mass, and drop at least one size. You’ll also enjoy thicker, shinier hair; clear, glowing skin; a remarkable improvement in your overall appearance; reduced joint pain and other inflammations; increased energy; and better sleep.Filled with tips and resources on supplements and cleansing, dozens of delicious, healthy recipes and advice on how to adjust your eating when traveling and on vacation, Body Love is your one-stop resource to living clean and happy!

    The microbiome—the collective name for the trillions of bacteria that live in our gut—is today’s hottest medical news topic. Synthesizing the latest findings, Dr. Robynne Chutkan explains how the standard Western diet and lifestyle are starving our microbiome, depleting the “good bugs” that keep us healthy and encouraging overgrowth of exactly the wrong type of bacteria. The resulting imbalance makes us more prone to disease and obesity and negatively affects our metabolism, our hormones, our cravings, our immunity, and even our genes. But beyond the science, what sets this book apart is Dr. Chutkan’s powerful three-level program for optimizing your gut bacteria for good health.Dr. Chutkan shares:Why hand-sanitizing gels and antibiotics are stripping our bodies of their natural protective systemsEssential prebiotics and probioticsRecipes with ingredients that replenish the microbiome for each rehab levelCutting-edge research on the connection between the microbiome and the brainAn intro to the stool transplant, the superfix for a severely troubled microbiome Dr. Chutkan is one of the most recognizable gastroenterologists working in America today, and this is the first book to distill the research into a practical, effective plan for replenishing our microbiomes. The Microbiome Solution will bring welcome relief to the millions who want to grow a good “gut garden”—and enjoy healthier, happier lives.