What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound:• A figure skater whose body has become a ticking time-bomb • A salesman who drives around and around a traffic rotary, unable to get off • A college quarterback who can't stop calling the same play • A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive • A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth livingHow does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance.

    In Emotions Revealed, he assembles his research and theories to provide a comprehensive look at the evolutionary roots of human emotions, including anger, sadness, fear, disgust, and happiness. Drawing on decades of fieldwork, Ekman shows that emotions are deeply embedded in the human species. In the process, he answers such questions as: What triggers emotions and can we stop them? How does our body signal to others whether we are slightly sad or anguished, peeved or enraged? Can we learn to distinguish between a polite smile and the genuine thing? Can we ever truly control our emotions? Unique exercises and photographs help readers identify emotions in themselves and others. Emotions Revealed is a practical, mind-opening, and potentially life-changing exploration of science and self. c

    Molecular Cell Biology stands out from its peers in this course in that it provides a clear introduction to the techniques and experiments of scientists past and present, not just an "encyclopedia" of information.  This experimental emphasis, together with a solid pedagogical framework in the chapters, provides the clearest, most cutting-edge text available.

    Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Includes tables to compare different agents within a given class of drugs. For use as a review for Boards, self-testing, or reference. Previous edition: c1997.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    The book features case discussions, USMLE-style questions, and a USMLE-style practice exam.

    Simply put, beliefs come first and explanations for beliefs follow. The brain, Shermer argues, is a belief engine. From sensory data flowing in through the senses, the brain naturally begins to look for and find patterns, and then infuses those patterns with meaning. Our brains connect the dots of our world into meaningful patterns that explain why things happen, and these patterns become beliefs. Once beliefs are formed the brain begins to look for and find confirmatory evidence in support of those beliefs, which accelerates the process of reinforcing them, and round and round the process goes in a positive-feedback loop of belief confirmation. Shermer outlines the numerous cognitive tools our brains engage to reinforce our beliefs as truths.Interlaced with his theory of belief, Shermer provides countless real-world examples of how this process operates, from politics, economics, and religion to conspiracy theories, the supernatural, and the paranormal. Ultimately, he demonstrates why science is the best tool ever devised to determine whether or not a belief matches reality.

    This amazing organ has unique powers to make predictions about the future, form relationships with other people, adapt to rapidly changing circumstances, and so much more. We all have a basic conception of how our brains function, but when did you last dive into the fascinating world of neuroscience to truly understand the inner workings of your mind? For decades, the field of neuroscience has been in a near-constant state of disruptive transformation, as we continually learn more about our incredible brains. Thanks to rapid advances in technology and in our understanding of the brain, today’s neuroscience research goes far beyond trying to understand how the brain works, and into the search for proven ways to optimize brain performance. In Your Best Brain, Professor John J. Medina - an award-winning scientist, New York Times best-selling author, and leading advocate for brain research - delivers 24 exciting lectures that probe the origins of consciousness, memory, emotion, attention, intelligence, and beyond. He focuses on five key areas of study in neuroscience: the brain’s physical structure and function, and how it enabled us to become the planet’s apex predator; the ways in which the brain processes information, and how that relates to intelligence; the intricacies of emotions and socialization, and how empathy is a vital survival mechanism; how our brains develop and change throughout our lifetimes; and how we can best use and expand our cerebral processing performance. After gaining a thorough understanding of the science behind your best brain, you’ll learn scientifically proven methods for improving your memory, boosting your creativity, and keeping your mind sharp for years to come.

    Marieb and Katja Hoehn have produced the most accessible, comprehensive, up-to-date, and visually stunning anatomy & physiology textbook on the market. Marieb draws on her career as an A&P professor and her experience as a part-time nursing student, while Hoehn relies on her medical education and classroom experience to explain concepts and processes in a meaningful and memorable way. The most significant revision to date, the Eighth Edition makes it easier for you to learn key concepts in A&P. The new edition features a whole new art program that is not only more visually dynamic and vibrant than in previous editions but is also much more pedagogically effective for today's students, including new Focus figures, which guide you through the toughest concepts in A&P. The text has been edited to make it easier than ever to study from and navigate, with integrated objectives, new concept check questions, and a new design program.

    Looks at enduring myths such as "Do we only use 10% of our brain?," "Pregnant women lose their mind," "Right-brained people are more creative" and many more. Delves into myths relating to specific brain disorders, including epilepsy, autism, dementia, and others. Written engagingly and accessibly for students and lay readers alike, providing a unique introduction to the study of the brain. Teaches readers how to spot neuro hype and neuro-nonsense claims in the media.

    Told here for the first time, the dramatic tale of how the secrets of the brain were discovered in seventeenth-century England unfolds against a turbulent backdrop of civil war, the Great Fire of London, and plague. At the beginning of that chaotic century, no one knew how the brain worked or even what it looked like intact. But by the century's close, even the most common conceptions and dominant philosophies had been completely overturned, supplanted by a radical new vision of man, God, and the universe. Presiding over the rise of this new scientific paradigm was the founder of modern neurology, Thomas Willis, a fascinating, sympathetic, even heroic figure at the center of an extraordinary group of scientists and philosophers known as the Oxford circle. Chronicled here in vivid detail are their groundbreaking revelations and the often gory experiments that first enshrined the brain as the physical seat of intelligence -- and the seat of the human soul. Soul Made Flesh conveys a contagious appreciation for the brain, its structure, and its many marvelous functions, and the implications for human identity, mind, and morality.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Embracing the unifying themes of 'symptom endophenotypes', dimensions of psychopathology that cut across syndromes, and 'symptoms and circuits', every aspect of the text has been updated to the frontiers of current knowledge, with the clarity of explanation and illustration that only Dr Stahl can bring. Integrating much of the basic neuroscience into the clinical chapters, and with major additions in the areas of psychosis, antipsychotics, antidepressants, impulsivity, compulsivity and addiction, this is the single most readily readable source of information on disease and drug mechanisms. This remains the essential text for all students and professionals in mental health seeking to understand and utilize current therapeutics, and to anticipate the future for novel medications.