Pharmaceutical breakthroughs such as anti­biotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on pre­scription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. Pharma introduces brilliant scientists, in-corruptible government regulators, and brave whistleblowers facing off against company exec­utives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers’ rise to power—revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. Pharma reveals how and why American drug com­panies have put earnings ahead of patients.

    Often they seem aloof, uncaring, and hurried. Of course, they’re not all like that, and most didn’t start out that way. Here are voices of third-year students just as they begin to take on clinical responsibilities. Their words focus on the odd transition students face when they must deal with real people in real time and in real crises and when they must learn to put aside their emotions to make quick, accurate, and sensitive decisions. Their decisions aren’t always right, and the consequences can be life-altering—for all involved. Moving, disturbing, and candid, their true stories show us a side of the profession that few ever see, or could even imagine. They show, often painfully, how medical students grow up, right at the bedside.

    Now the director of the Heart Failure Program at a Long Island hospital, Jauhar uses his own story as a scalpel to lay open the American health-care system.The patient is ill indeed. A perverse system forces doctors to prescribe unnecessary tests and participate in an elaborate system of cronyism just to cover costs and protect themselves from malpractice suits. Jauhar reports cases where a single patient might see fifteen specialists in one hospital stay, fail to receive a full picture of his actual condition, and leave with a bill for hundreds of thousands of dollars. Jauhar himself wrestles with his conscience as, struggling to make ends meet, he moonlights for a practitioner who charges exorbitant fees for tests of questionable value.Doctored is a cry for reform; a fascinating look at what really goes on in examining rooms, ORs, and your own doctor’s mind; and, most of all, a deeply personal and unsparing act of introspection by a physician who wants to return meaning and moral grounding to a noble profession that has lost its way. It is certain to kick off controversy and heated debate at a time when the dysfunctionalities of our health-care system remain at the top of the nation’s agenda.

    Uzzi Reiss shows the way for women who want to turn back the effects of time through natural hormone therapy, but who wonder: is it safe? Does it work? Is hormone therapy right for me?Natural Hormone Balance for Women is Dr. Reiss's breakthrough, step-by-step program for women who want to take control of their lives by restoring hormonal balance. This revolutionary, commonsense natural hormone replacement program is designed to meet the individual needs of most women looking to rejuvenate body and mind—and offers astounding benefits for women of all ages: More energy and stamina * Improved memory * Healthier, more youthful skin * Balanced moods * Less depression and anxiety * Stabilization of weight and more muscle definition * Better sleep patterns * PMS and menopausal symptoms reduced or eliminated * Enhanced sexuality Dr. Reiss takes the confusion out of the medical information you need to know. In clear, nontechnical language, he thoroughly explains: -the important difference between standard chemical hormone prescriptions and natural hormone replacements -which hormone replacements are best for you and how to adjust them to your maximum individual benefit -how to take hormones without worry -how to choose the most effective hormonal gel, cream, pill, or sublingual drops, and when to use them. Dr. Reiss has helped thousands of women transform their lives by achieving natural hormone balance. Now you can tap into the replenishing "fountain of youthfulness" that is not only essential for better life, but easier and safer to achieve than ever before.

    With extensive treatment of the heart of epidemiology-from study designs to descriptive epidemiology to quantitative measures-this reader-friendly text is accessible and interesting to a wide range of beginning students in all health-related disciplines. A unique focus is given to real-world applications of epidemiology and the development of skills that students can apply in subsequent course work and in the field. The text is also accompanied by a complete package of instructor and student resources available through a companion Web site.

    Because of his studies of the Eskimos, his discoveries of land, the application of new ideas and new methods of exploration, Stefansson was considered the foremost polar explorer of his day, and one of the few great explorers of all time. During a period of three or four years Mr. Stefansson has produced a creditable list of books about the Arctic. In some respects his service in publishing the results of his Northern studies has differed from that of earlier explorers. He has challenged our preconceptions about the Arctic. “Hunters of the Great North” gives details of Northern life such as have doubtless come within the experience of all Arctic explorers, but which are new to the average American reader. In short, it is an elementary text-book of the Arctic. Stefansson lived among the Eskimos of the Mackenzie River, studying their language and adopting their mode of life, and spending ten winters and thirteen summers in the polar regions. Among Stefannson's most famous discovery was that of a race of blond Eskimo on Coronation Gulf. Stefansson writes: "In the present book I have tried by means of diaries and memory to go back to the vivid impressions of my first year among the Eskimos for the story of what I saw and heard." In describing his confrontation with a polar bear, Stefansson writes: “I heard behind me a noise like the spitting of a cat or the hiss of a goose. I looked back and saw, about twenty feet away and almost above me, a polar bear. I had overestimated the bear's distance from shore, and had passed the spot where he lay. From his eye and attitude, as well as the story his trail told afterward there was no doubting his intentions: the hiss was merely his way of saying, "Watch me do it!" Or at least that is how I interpreted it; possibly the motive was chivalry, and the hiss was his way of saying Garde!” Contents I. PREPARATIONS FOR A LIFEWORK OF EXPLORATION II. DOWN THE MACKENZIE RIVER THROUGH 2000 MILES OF INDIAN COUNTRY III. FIRST IMPRESSIONS OF THE ESKIMOS IV. CAPTAIN KLINKENBERG—SEA WOLF AND DISCOVERER V. THE WHALING FLEET SAILS AWAY VI. LEARNING TO LIVE AS AN ESKIMO—ON A DIET OF FISH WITHOUT SALT VII. HOW AN ESKIMO SAILED THROUGH THE STORM VIII. AN AUTUMN JOURNEY THROUGH ARCTIC MOUNTAINS IX. THE SUN GOES AWAY FOR THE WINTER X. LOST IN THE MACKENZIE DELTA XI. AN ARCTIC CHRISTMAS WITH AN ENGLISH COUNTRY GENTLEMAN XII. THE LIFE AT TUKTUYAKTOK XIII. LEARNING TO BUILD A SNOWHOUSE AND TO BE COMFORTABLE IN ONE XIV. TRAVELS AFTER THE SUN CAME BACK XV. WE GO IN SEARCH OF OUR OWN EXPEDITION XVI. A SPRING JOURNEY IN AN ESKIMO SKIN BOAT XVII. A RACE OVER THE ARCTIC MOUNTAINS IN SUMMER XVIII. ON A RAFT DOWN THE PORCUPINE RIVER SHORT STORIES OF ADVENTURE I. HOW I LEARNED TO HUNT CARIBOU II. HOW I LEARNED TO HUNT SEALS III. HOW WE HUNT POLAR BEARS

    This all-purpose CCNA study guide methodically covers all the objectives of the ICND1 (100-101) and ICND2 (200-101) exams as well as providing additional insight for those taking CCNA Composite (200-120) exam. It thoroughly examines operation of IP data networks, LAN switching technologies, IP addressing (IPv4/IPv6), IP routing technologies, IP services, network device security, troubleshooting, and WAN technologies.Valuable study tools such as a companion test engine that includes hundreds of sample questions, a pre-assessment test, and multiple practice exams. Plus, you'll also get access to hundreds of electronic flashcards, author files, and a network simulator.CCNA candidates may choose to take either the ICND1(100-101) and ICND2 (200-101) exams or the CCNA Composite exam (200-120); this study guide covers the full objectives of all three Written by bestselling Sybex study guide author Todd Lammle, an acknowledged authority on all things Cisco Covers essential Cisco networking topics such as operating an IP data network, IP addressing, switching and routing technologies, troubleshooting, network device security, and much more Includes a comprehensive set of study tools including practice exams, electronic flashcards, comprehensive glossary of key terms, videos, and a network simulator that can be used with the book's hands-on labs Bonus Content: Access to over 40 MicroNugget videos from CBT Nuggets CCNA Routing and Switching Study Guide prepares you for CCNA certification success.

    "A graphic account of what it's like when a doctor crosses to the other side of the table and becomes a patient himself."—Parade Magazine

    

    Although it has a long history, the recent discovery (1992) of the body's widespread endocannabinoid system (ECS) has thrust cannabis back into the limelight again as a viable medicine. In 2012 over 2.5 million prescriptions were written for medical marijuana in the United States. CBD and THC are both cannabinoids found in cannabis. However, while THC produces a “high” in the user, CBD does not. And now legal CBD-rich hemp oil is available over-the-counter in all 50 states, without a prescription. It was discovered that the Hemp Family of plants (cannabis, marijuana) is loaded with cannabinoids that stimulate our ECS receptor sites. These sites are found in the brain, organs, glands, connective tissue and immune cells and plays regulatory roles in many physiological processes including appetite, pain-sensation, mood and memory. The primary purpose of this system revolves around maintaining balance in the body. Cannabinoids found in all varieties of cannabis work in harmony with the cannabinoids we naturally produce when our system is functioning properly. It is now coming to light that we may very well be “Endocannabinoid Deficient” and supplementing with Cannabidiol, known as CBD, may provide just what we’re missing to restore optimum health. The health benefits of cannabidiol (CBD) from natural hemp oil is this book's primary focus. It explores the similarities, differences, uses and benefits of hemp, cannabis and medical marijuana along with the interplay of THC and CBD. Their 480 other components are also discussed, such as terpenoids, flavonoids, enzymes, vitamins, etc. Make no mistake about it, the endocannabinoid system, although newly discovered, is just as important as any other bodily system, like the muscular, cardiac, circulatory or digestive system. The ECS requires its own specialized medicine as found in the Hemp Family of plants, which is also known as cannabis, and which includes all strains of marijuana. Here is a list of conditions known and/or being researched that may be helped by cannabinoid therapeutics and supplementation: Acne ADD/ADHD Addiction AIDS ALS (Lou Gehrig's Disease) Alzheimer’s Anorexia Antibiotic Resistance Anxiety Atherosclerosis Arthritis Asthma Autism Bipolar Cancer Colitis/Crohn’s Depression Diabetes Endocrine Disorders Epilepsy/Seizure Fibromyalgia Glaucoma Heart Disease Huntington’s Inflammation Irritable Bowel Kidney Disease Liver Disease Metabolic Syndrome Migraine Mood Disorders Motion Sickness Multiple Sclerosis Nausea Neurodegeneration Neuropathic Pain Obesity OCD Osteoporosis Parkinson’s Prion/Mad Cow Disease PTSD Rheumatism Schizophrenia Sickle Cell Anemia Skin Conditions Sleep Disorders Spinal Cord Injury Stress Stroke/TBI 10% of the proceeds from sales of this book will be donated to the American Cannabis Nurses Association in an effort to bring together nurses, to share, integrate and one day certify nurses in the science of endocannabinoid therapeutics in nursing practice.

    At once a riveting story of the birth of an enterprise—ala Tracy Kidder’s The Soul of a New Machine—and a inspiring tale of the indomitable human spirit in the vein of Erin Brockovich and A Civil Action, The Cure is a testament to ingenuity, unflagging will, and unconquerable love.

    But Max Leonard, himself an accomplished amateur cyclist, does not forget the pain, the glory, the sweat, and the tears that go into these grueling climbs.  After all, cycling up a mountain is hard.  So hard that, to many, it can seem absurd. But for others, climbing a mountain gracefully (and beating your competitors up the slope) represents the pinnacle of cycling achievement. It is where legends are forged.Many books tell you where the mountains are, or how long and how high. None of them ask why. Why are mountain ranges professional cycling’s Coliseum? Why do amateurs also make pilgrimages to these high, remote roads? Why are the roads even there in the first place to lure us on to these obsession inducing climbs?   Just why are mountains so enthralling? “This is real cycling, where the glory is and where dreams come true,” according to Bradley Wiggins. Mountains are where cycling's greatest heroes have made their names. Every amateur rider wishes they could climb better, too.  Are all these people addicted to the pain? To the achievement? Or to the allure of the peaks? Some spend their weekends and holidays cycling up mountains from start to finish. But how does a rider push themselves beyond their limits to get up a 10% gradient on pedal power alone? What is happening when they do?A Higher Calling explores the central place of mountains in the folklore of road cycling. Blending adventure and travel writing with the rich narrative of racing, Max Leonard takes the reader from the battles that created the Alpine roads to the shepherds tending their flocks on the peaks, and to a Grand Tour climax on the “highest road in Europe.” And he tells stories of courage and sacrifice, war and love, obsession and even elephants, along the way.

    Touch it and you die. Every politician knows this truism, which is why no one wants to debate it. Privately, many of them understand that the health care system, which costs about $200 billion a year in public and private money, cannot continue as it is—increasingly ill-adapted to an aging population with public costs growing faster than government revenues. In Chronic Condition, Jeffrey Simpson meets health care head on and explores the only four options we have to end this growing crisis: cuts in spending, tax increases, privatization, and reaping savings through increased efficiency. He examines the tenets of the Medicare system that Canadians cling to so passionately. Here, he finds that many other countries have more extensive public health systems, and Canadian health care produces only average value for money. In fact, our rigid system for some health care needs and a costly system for other needs—drugs, dentistry, and home care—is really the worst of both worlds. Chronic Condition breaks the silence about the huge changes and real choices that Canadians face.

    The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    But that picture is vastly incomplete. In this eye-opening book, physician Rishi Manchanda says that our health may depend even more on our social and environmental settings than it does on our most cutting-edge medical care. Manchanda argues that that the future of our health care depends on growing a new generation of health care practitioners. We need doctors who look upstream for the sources of our problems, rather than simply go for quick-hit symptomatic relief. These upstreamists, as he calls them, are doctors and nurses on the frontlines of medicine who see that health (like sickness) is more than a chemical equation that can be balanced with pills and procedures administered within clinic walls. They see that health begins in our everyday lives, in the places where we live, work, eat, and play. If our high-cost, sick-care system is to become a high-value, health care system, the upstreamists will show us the way. (Description taken from TED Library: http://www.ted.com/pages/tedbooks_lib...)