As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Cory Franklin. Filled with stories of strange medical cases and unforgettable patients culled from a thirty-year career in medicine, Cook County ICU offers readers a peek into the inner workings of a hospital. Author Dr. Cory Franklin, who headed the hospital’s intensive care unit from the 1970s through the 1990s, shares his most unique and bizarre experiences, including the deadly Chicago heat wave of 1995, treating some of the first AIDS patients in the country before the disease was diagnosed, the nurse with rare Munchausen syndrome, the first surviving ricin victim, and the famous professor whose Parkinson’s disease hid the effects of the wrong medication. Surprising, darkly humorous, heartwarming, and sometimes tragic, these stories provide a big-picture look at how the practice of medicine has changed over the years, making it an enjoyable read for patients, doctors, and anyone with an interest in medicine.

    The bedrock, the topsoil, and everything in between that generates the health of your local watershed. In his new book, Nick takes a humorous, inspiring, and elucidating trip to America's trails, farms, and frontier to celebrate the people, landscape, and stories, both historical and fresh, that have made it great.The seeds of this book were planted in 2019, when Nick took two memorable journeys with friends--a hiking trip to Glacier National Park with his friends Jeff Tweedy and George Saunders, as well as an extended visit to his friend James Rebanks, the author of A Shepherd's Life and English Pastoral. He followed that up with an excursion that could only have come about in 2020--Nick and his wife, Megan Mullally, bought an Airstream trailer to drive across the US in late 2020. All three journeys inspired some "deep-ish thinking from Nick, about the history and philosophy of our relationship with nature in our national parks, in our farming, and in our wildlife; what we mean when we talk about conservation; the importance of outdoor recreation; and the healthy building of both local and national communities across party lines, all subjects very close to Nick's heart.With witty, heartwarming stories, and a keen insight into the problems we all confront, this is both a ramble through and celebration of the land we all love.

    In this deeply personal show, the legendary Peabody Award-winning journalist takes audiences through the most pivotal moments of his life, from surviving a debilitating illness as a child in Depression-era Texas to covering monumental moments in American history such as the Civil Rights movement, the assassination of JFK, and Watergate. An intimate evening of candid commentary, memories, and laughter, Stories of a Lifetime is a celebration of the power of a free press and reminder of why it’s more important now than ever.©2020 Dan Rather (P)2020 AO Media LLC

    An exhilarating account of Sapolsky’s twenty-one-year study of a troop of rambunctious baboons in Kenya, A Primate’s Memoir interweaves serious scientific observations with wry commentary about the challenges and pleasures of living in the wilds of the Serengeti — for man and beast alike. Over two decades, Sapolsky survives culinary atrocities, gunpoint encounters, and a surreal kidnapping, while witnessing the encroachment of the tourist mentality on the farthest vestiges of unspoiled Africa. As he conducts unprecedented physiological research on wild primates, he becomes evermore enamored of his subjects — unique and compelling characters in their own right — and he returns to them summer after summer, until tragedy finally prevents him.By turns hilarious and poignant, A Primate’s Memoir is a magnum opus from one of our foremost science writers.

     Desert Notebooks examines how the unprecedented pace of destruction to our environment and an increasingly unstable geopolitical landscape have led us to the brink of a calamity greater than any humankind has confronted before. As inhabitants of the Anthropocene, what might some of our own histories tell us about how to confront apocalypse? And how might the geologies and ecologies of desert spaces inform how we see and act toward time--the pasts we have erased and paved over, this anxious present, the future we have no choice but to build? Ehrenreich draws on the stark grandeur of the desert to ask how we might reckon with the uncertainty that surrounds us and fight off the crises that have already begun.In the canyons and oases of the Mojave and in Las Vegas's neon apocalypse, Ehrenreich finds beauty, and even hope, surging up in the most unlikely places, from the most barren rocks, and the apparent emptiness of the sky. Desert Notebooks is a vital and necessary chronicle of our past and our present--unflinching, urgent--yet timeless and profound.

    Chelsea Handler, 1.5 oz. Nora Ephron, finish with a twist of Tina Fey, and you get Ali in Wonderland, the uproarious, revealing, and heartfelt memoir from acclaimed actress and comedian Ali Wentworth. Whether spilling secrets about her quintessentially WASPy upbringing (and her delicious rebellion against it), reminiscing about her Seinfeld “Schmoopie” days and her appearances on The Oprah Winfrey Show, The View, and The Tonight Show with Jay Leno, or baring the details of starting a family alongside husband George Stephanopoulos, one thing is for sure—Ali has the unsurpassable humor and warmth of a born storyteller with a story to tell: the quirky, flavorful, surprising, and sometimes scandalous Ali in Wonderland.“Ali Wentworth is funny and warm and crazy all at once. Like Barbara Eden. But on something. Like crystal meth.” —Alec Baldwin

    But for many years Maeve was a journalist, writing for The Irish Times.From 'The Student Train' to 'Plane Bores', 'Bathroom Joggers' to 'When Beckett met Binchy', these articles have all the warmth, wit and humanity of her fiction. Arranged in decades, from the 1960s to the 2000s, and including Maeve's first and last ever piece of writing for The Irish Times, the columns also give a fascinating insight into the author herself.With an introduction written by her husband, the writer Gordon Snell, this collection of timeless writing reminds us of why the leading Irish writer was so universally loved.

    Her compelling and demanding collection The Death of Adam—in which she reflected on her Presbyterian upbringing, investigated the roots of Midwestern abolitionism, and mounted a memorable defense of Calvinism—is respected as a classic of the genre, praised by Doris Lessing as “a useful antidote to the increasingly crude and slogan-loving culture we inhabit.” In this new collection she returns to the themes which have preoccupied her work: the role of faith in modern life, the inadequacy of fact, the contradictions inherent in human nature. Clear-eyed and forceful as ever, Robinson demonstrates once again why she is regarded as a modern rhetorical master.

    But no matter where she was transplanted--no matter how awkward the fit or forbidding the landscape--she was able to turn to our world's fierce and funny creatures for guidance."What the peacock can do," she tells us, "is remind you of a home you will run away from and run back to all your life." The axolotl teaches us to smile, even in the face of unkindness; the touch-me-not plant shows us how to shake off unwanted advances; the narwhal demonstrates how to survive in hostile environments. Even in the strange and the unlovely, Nezhukumatathil finds beauty and kinship. For it is this way with wonder: it requires that we are curious enough to look past the distractions in order to fully appreciate the world's gifts.Warm, lyrical, and gorgeously illustrated by Fumi Nakamura, World of Wonders is a book of sustenance and joy.

    Widely known for his roles in the films Big Fan and Ratatouille, as well as the television hit The King of Queens, Patton Oswalt—a staple of Comedy Central—has been amusing audiences for decades. Now, with Zombie Spaceship Wasteland, he offers a fascinating look into his most unusual, and lovable, mindscape. Oswalt combines memoir with uproarious humor, from snow forts to Dungeons & Dragons to gifts from Grandma that had to be explained. He remem­bers his teen summers spent working in a movie Cineplex and his early years doing stand-up. Readers are also treated to several graphic elements, includ­ing a vampire tale for the rest of us and some greeting cards with a special touch. Then there’s the book’s centerpiece, which posits that before all young creative minds have anything to write about, they will home in on one of three story lines: zom­bies, spaceships, or wastelands. Oswalt chose wastelands, and ever since he has been mining our society’s wasteland for perversion and excess, pop culture and fatty foods, indie rock and single-malt scotch. Zombie Spaceship Wasteland is an inventive account of the evolution of Patton Oswalt’s wildly insightful worldview, sure to indulge his legion of fans and lure many new admirers to his very entertaining “wasteland.”

    #1 NEW YORK TIMES BESTSELLEREveryone’s favorite Idiot Girl, Laurie Notaro, is just trying to find the right fit, whether it’s in the adorable blouse that looks charming on the mannequin but leaves her in a literal bind or in her neighborhood after she’s shamefully exposed at a holiday party by delivering a low-quality rendition of “Jingle Bells.” Notaro makes misstep after riotous misstep as she shares tales of marriage and family, including stories about the dog-bark translator that deciphers Notaro’s and her husband’s own “woofs” a little too accurately, the emails from her mother with “FWD” in the subject line (“which in email code means Forecasting World Destruction”), and the dead-of-night shopping sprees and Devil Dog–devouring monkeyshines of a creature known as “Ambien Laurie.” At every turn, Notaro’s pluck and irresistible candor set the New York Times bestselling author on a journey that’s laugh-out-loud funny and utterly unforgettable.

    The GQ correspondent and Deadspin columnist’s stories about trying to raise a family have attracted millions of readers online. And now he’s finally bringing that unique voice to a memoir. In Someone Could Get Hurt, he reflects on his own parenting experiences to explore the anxiety, rationalizations, compromises, and overpowering love that come with raising children in contemporary America. In brutally honest and funny stories, Magary reveals how American mothers and fathers cope with being in over their heads (getting drunk while trick-or-treating, watching helplessly as a child defiantly pees in a hotel pool, engaging in role-play with a princess-crazed daughter), and how stepping back can sometimes make all the difference (talking a toddler down from the third story of a netted-in playhouse, allowing children to make little mistakes in the kitchen to keep them from making the bigger ones in life). It’s a celebration of all the surprises—joyful and otherwise—that come with being part of a real family. In the wake of recent bestsellers that expose how every other culture raises their children better, Someone Could Get Hurt offers a hilarious and heartfelt defense of American child rearing with a glimpse into the genuine love and compassion that accompany the missteps and flawed logic. It’s the story of head lice, almost-dirty words, and flat head syndrome, and a man trying to commit the ultimate act of selflessness in a selfish world.

    facilities. For Hargrove, becoming an orca trainer fulfilled a childhood dream. However, as his experience with the whales deepened, Hargrove came to doubt that their needs could ever be met in captivity. When two fellow trainers were killed by orcas in marine parks, Hargrove decided that SeaWorld's wildly popular programs were both detrimental to the whales and ultimately unsafe for trainers.After leaving SeaWorld, Hargrove became one of the stars of the controversial documentary Blackfish. The outcry over the treatment of SeaWorld's orca has now expanded beyond the outlines sketched by the award-winning documentary, with Hargrove contributing his expertise to an advocacy movement that is convincing both federal and state governments to act.In Beneath the Surface, Hargrove paints a compelling portrait of these highly intelligent and social creatures, including his favorite whales Takara and her mother Kasatka, two of the most dominant orcas in SeaWorld. And he includes vibrant descriptions of the lives of orcas in the wild, contrasting their freedom in the ocean with their lives in SeaWorld.Hargrove's journey is one that humanity has just begun to take-toward the realization that the relationship between the human and animal worlds must be radically rethought.

    Our books shape us, define us, enchant us, and even sometimes infuriate us. Our books are a part of who we are as people, and we can't imagine life without them.I'd Rather Be Reading is the perfect literary companion for everyone who feels that way. In this collection of charming and relatable reflections on the reading life, beloved blogger and author Anne Bogel leads readers to remember the book that first hooked them, the place where they first fell in love with reading, and all of the moments afterward that helped make them the reader they are today. Known as a reading tastemaker through her popular podcast What Should I Read Next?, Bogel invites book lovers into a community of like-minded people to discover new ways to approach literature, learn fascinating new things about books and publishing, and reflect on the role reading plays in their lives.The perfect gift for the bibliophile in everyone's life, I'd Rather Be Reading will command an honored place on the overstuffed bookshelves of any book lover.