The circumstances of her disappearance are far from ordinary, a fact that only fellow student Melissa Lopez appears to appreciate. Motivated by an unexplained and disturbing voicemail message from Anna on the night of her disappearance, Melissa's curiosity quickly turns into a deeper investigation, an obsession even, which she chronicles as a regular podcast - the very recordings that you are about to listen to. She quickly discovers that Anna was a loner with hearing difficulties and had disappeared for a week earlier in the year, only to return with perfect hearing, but with increasingly unstable

    In this book, he expands the points he has made, and claims that this debate is not so much about religion versus science, as about the nature of science itself. With infectious enthusiasm, he reveals the mechanics of evolutionary theory, explains how it is rooted in the testable and verifiable scientific method, and why it is therefore a sound explanation of our beginning. He argues passionately that to continue to assert otherwise, to continue to insist that creationism has a place in the science classroom is harmful not only to our children, but to the future of the greater world as well.

    At the time, Curie was in the throes of a scandal in France over her affair with Paul Langevin, which threatened to overshadow the accomplishment of her second Nobel Prize.Performed by Kate Mulgrew and Francesca Faridany, this play by Lauren Gunderson is an ode to two remarkable women who, despite tremendous personal and professional obstacles, continued to devote their lives to scientific innovation and social change.Playwright Lauren Gunderson was awarded a commission through the Audible Emerging Playwrights Fund, an initiative dedicated to developing innovative original plays driven by language and voice. As an Audible commissioned playwright, she received funding and creative support to develop The Half-Life of Marie Curie.Directed by Gaye Taylor UpchurchSound design by Darron L West

    The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.Sulfa saved millions of lives—among them those of Winston Churchill and Franklin Delano Roosevelt Jr.—but its real effects are even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold; transformed the way doctors treated patients; and ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness. A strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel. For thousands of years, humans had sought medicines with which they could defeat contagion, and they had slowly, painstakingly, won a few battles: some vaccines to ward off disease, a handful of antitoxins. A drug or two was available that could stop parasitic diseases once they hit, tropical maladies like malaria and sleeping sickness. But the great killers of Europe, North America, and most of Asia—pneumonia, plague, tuberculosis, diphtheria, cholera, meningitis—were caused not by parasites but by bacteria, much smaller, far different microorganisms. By 1931, nothing on earth could stop a bacterial infection once it started. . . .But all that was about to change. . . . —from The Demon Under the Microscope

    

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    That judgment, implausible even to a casual fan, also contradicted the opinion of a growing cadre of neuroscientists who worked in vain to convince the NFL that it was facing a deadly new scourge: A chronic brain disease that was driving an alarming number of players -- including some of the all-time greats -- to madness.League of Denial reveals how the NFL, over a period of nearly two decades, sought to cover up and deny mounting evidence of the connection between football and brain damage.Comprehensively, and for the first time, award-winning ESPN investigative reporters Mark Fainaru-Wada and Steve Fainaru tell the story of a public health crisis that emerged from the playing fields of our 21st century pastime. Everyone knew that football is violent and dangerous. But what the players who built the NFL into a $10 billion industry didn’t know – and what the league sought to shield from them – is that no amount of padding could protect the human brain from the force generated by modern football; that the very essence of the game could be exposing these players to brain damage.In a fast-paced narrative that moves between the NFL trenches, America’s research labs and the boardrooms where the NFL went to war against science, League of Denial examines how the league used its power and resources to attack independent scientists and elevate its own flawed research -- a campaign with echoes of Big Tobacco’s fight to deny the connection between smoking and lung cancer. It chronicles the tragic fates of players like Hall of Fame Pittsburgh Steelers center Mike Webster, who was so disturbed at the time of his death he fantasized about shooting NFL executives; and former Chargers great Junior Seau, whose diseased brain became the target of an unseemly scientific battle between researchers and the NFL. Based on exclusive interviews, previously undisclosed documents and private emails, this is the story of what the NFL knew and when it knew it – questions at the heart of crisis that threatens football, from the highest levels all the way down to Pop Warner.

    Tell Me Where It Hurts: A Day of Humor, Healing, and Hope in My Life as an Animal Surgeon

    Fortunately, many smart philosophers have been pondering this conundrum for millennia and they have guidance for us. With bright wit and deep insight, How to Be Perfect explains concepts like deontology, utilitarianism, existentialism, ubuntu, and more so we can sound cool at parties and become better people. Schur starts off with easy ethical questions like “Should I punch my friend in the face for no reason?” (No.) and works his way up to the most complex moral issues we all face. Such as: Can I still enjoy great art if it was created by terrible people? How much money should I give to charity? Why bother being good at all when there are no consequences for being bad? And much more. By the time the book is done, we’ll know exactly how to act in every conceivable situation, so as to produce a verifiably maximal amount of moral good. We will be perfect, and all our friends will be jealous. OK, not quite. Instead, we’ll gain fresh, funny, inspiring wisdom on the toughest issues we face every day.

    Written in two distinctive styles, it reflects the larger-than-life personalities of its authors, Jack and Michael Whitehall.'This book is a portrait of the pretty odd relationship I have with my elderly father. It's given me an opportunity to share memories of him losing his temper with foreigners on holidays, being rude to my mother's family at Christmas and failing epically during the fathers' race at my prep school. He's also written some stories about me, but can I just say, before you read anything, that I recall being a calm, well-behaved and learned child, not the intellectually subnormal, mal-coordinated dipshit that he paints me as. Nor am I, as he suggests inside, a sex addict, a flasher or a Scientologist.' - Jack'How dare Jack refer to me as elderly! People always tell me how young I look for my age. In this book, I have at last been able to recount the many occasions when I have been let down by my only son. He failed on the stage, the sports field and he even screwed up the interview for his first boarding school by pretending he had mental health issues. Despite being practically illiterate, he tells stories about me, strewn with grammatical errors and peppered with endless exaggerations and lies. I was a kind, doting father, who guided his son through his formative years with love, care and respect.' - Michael'I'm not your only son, what about Barnaby?''Oh yes, I forgot about Barnaby.'Packed with anecdotes, some embarrassing and indiscreet, many warm and touching, Him & Me is lavishly illustrated with family photographs and Jack's original illustrations. Friends, relatives, neighbours, teachers, actors, none are safe once Jack and Michael have opened up the Whitehall archives and shared their hilarious memories with us.

    Most of the time this math works quietly behind the scenes . . . until it doesn't. All sorts of seemingly innocuous mathematical mistakes can have significant consequences.Math is easy to ignore until a misplaced decimal point upends the stock market, a unit conversion error causes a plane to crash, or someone divides by zero and stalls a battleship in the middle of the ocean.Exploring and explaining a litany of glitches, near misses, and mathematical mishaps involving the internet, big data, elections, street signs, lotteries, the Roman Empire, and an Olympic team, Matt Parker uncovers the bizarre ways math trips us up, and what this reveals about its essential place in our world. Getting it wrong has never been more fun.

    Like an overstuffed stocking on Christmas morning, NPR Holiday Favorites is full of unexpected pleasures and evergreen delights.• David Sedaris contributes his now classic “Santaland Diaries,” his account of his experiences playing Santa’s little helper at Macy’s in New York.• Susan Stamberg sneaks her mother-in-law’s recipe for cranberry relish onto the air—again.• Storyteller Kevin Kling finds an invitation to participate in a production of The Nutcracker too tempting to resist.• Ghanian-born commentator Meri Danquah shares her thoughts on Kwanzaa.• Cowboy poet Baxter Black describes a Christmas cookie with “the denseness of an anvil and the half-life of a radial tire.”• Robert Siegel goes in search of the correct spelling for December’s Jewish holiday.• The Thanksgiving tables are turned on unsuspecting Bostonians in “When Turkeys Attack.”And more...

    His memoir is a reflection on his diverse collection of experiences, both hilarious and heartbreaking.Short takes us through his career, from his early years with Second City Toronto and "Saturday Night Live" to his movie, stage, and television stardom. He recalls how he developed some of his enduring characters manic man-child Ed Grimley, elderly Tin Pan Alley songmith Irving Cohen, slimy lawyer Nathan Thurm, and the blubbery and bizarrely insensitive Jiminy Glick. Here, too, are his movie and television appearances, from the classic " Three Amigos!" to his Emmy-nominated role in "Damages," as well as his stage productions, including his Tony Award winning performance in "Little Me." Throughout, such friends and luminaries as Steve Martin, Tom Hanks, John Candy, Gilda Radner, Lorne Michaels, Nora Ephron, Frank Sinatra, and others share the spotlight.This deeply private man brings us into the circle of his family life, from raising his children to the legendary parties he and his wife hosted in their Los Angeles home. He recounts the pain of losing a brother and both parents by the time he was twenty and of the devastating death of Nancy, his wife of thirty years, in 2010. Despite the hardships, Short s life has been full of laughter, and he remains perennially upbeat. In this wise and entertaining memoir, he shares his irrepressible joy."

    It’s the perfect listen to devour as you’re strolling through the farmer’s market, washing the dishes, or planning your next dinner party.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.