Life's Greatest Secret: The Race to Crack the Genetic Code


Matthew Cobb - 2015
    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

A Many-Colored Glass (Page-Barbour Lectures)


Freeman Dyson - 2007
    The emphasis is, instead, on the myriad ways in which the universe presents itself to us--and how, as observers and participants in its processes, we respond to it. "Life, like a dome of many-colored glass," wrote Percy Bysshe Shelley, "stains the white radiance of eternity." The author seeks here to explore the variety that gives life its beauty.Taken from Dyson's recent public lectures--delivered to audiences with no specialized knowledge in hard sciences--the book begins with a consideration of the practical and political questions surrounding biotechnology. As he seeks how best to explain the place of life in the universe, Dyson then moves from the ethical to the purely scientific. The book concludes with an attempt to understand the implications of biology for philosophy and religion.The pieces in this collection touch on numerous disciplines, from astronomy and ecology to neurology and theology, speaking to the lay reader as well as to the scientist. As always, Dyson's view of human nature and behavior is balanced, and his predictions of a world to come serve primarily as a means for thinking about the world as it is today.

Psychology: A Concise Introduction


Richard A. Griggs - 2005
    At less than half the price of a standard textbook, it offers an affordable alternative.  A built-in Study Guide, written by the author, offers a practical suite of learning aids that foster review and self-assessment without the expense of a separate guide.

One Long Argument: Charles Darwin and the Genesis of Modern Evolutionary Thought


Ernst W. Mayr - 1991
    Its effects on our view of life have been wide and deep. One of the most world-shaking books ever published, Charles Darwin's On the Origin of Species, first appeared in print over 130 years ago, and it touched off a debate that rages to this day.Every modern evolutionist turns to Darwin's work again and again. Current controversies in the life sciences very often have as their starting point some vagueness in Darwin's writings or some question Darwin was unable to answer owing to the insufficient biological knowledge available during his time. Despite the intense study of Darwin's life and work, however, many of us cannot explain his theories (he had several separate ones) and the evidence and reasoning behind them, nor do we appreciate the modifications of the Darwinian paradigm that have kept it viable throughout the twentieth century.Who could elucidate the subtleties of Darwin's thought and that of his contemporaries and intellectual heirs--A. R. Wallace, T. H. Huxley, August Weismann, Asa Gray--better than Ernst Mayr, a man considered by many to be the greatest evolutionist of the century? In this gem of historical scholarship, Mayr has achieved a remarkable distillation of Charles Darwin's scientific thought and his enormous legacy to twentieth-century biology. Here we have an accessible account of the revolutionary ideas that Darwin thrust upon the world. Describing his treatise as "one long argument," Darwin definitively refuted the belief in the divine creation of each individual species, establishing in its place the concept that all of life descended from a common ancestor. He proposed the idea that humans were not the special products of creation but evolved according to principles that operate everywhere else in the living world; he upset current notions of a perfectly designed, benign natural world and substituted in their place the concept of a struggle for survival; and he introduced probability, chance, and uniqueness into scientific discourse.This is an important book for students, biologists, and general readers interested in the history of ideas--especially ideas that have radically altered our worldview. Here is a book by a grand master that spells out in simple terms the historical issues and presents the controversies in a manner that makes them understandable from a modern perspective.

Virus X


Frank Ryan - 1996
    But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

The End of Illness


David B. Agus - 2011
    David Agus tackles these fundamental questions and dismantles misperceptions about what “health” really means. Presenting an eye-opening picture of the human body and all the ways it works—and fails—Dr. Agus shows us how a new perspective on our individual health will allow us to achieve a long, vigorous life. Offering insights and access to powerful new technologies that promise to transform medicine, Dr. Agus emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that. A bold call for all of us to become our own personal health advocates, The End of Illness is a moving departure from orthodox thinking.

The Particles of the Universe


Jeff Yee - 2012
    Everything around us, including matter, is energy. A deep look into the mysteries of the subatomic world – the particles that make up the atom – provides answers to basic questions about how the universe works. To solve the future of mankind’s energy needs we need to understand the basic building blocks of the universe, including the atom and its parts. By exploring the subatomic world we’ll find more answers to our questions about time, forces like gravity and the matter that surrounds us. More importantly, we’ll find new ways to tap into the energy that exists around us to power our growing needs. In a new branch of particle physics, where tiny particles are thought of as energy waves, we find new answers that may help us in our quest to find alternative energy sources.

The Case Against Masks: Ten Reasons Why Mask Use Should be Limited


Judy Mikovits - 2020
    Judy Mikovits and Kent Heckenlively, this book reviews the evidence for and against widespread public masking as provided by the Centers for Disease Control and the Mayo Clinic, as well as top scientific publications such as the New England Journal of Medicine and The Lancet. This debate needs to take place without fear and paranoia. Important questions raised in this book are the affect of masks on oxygen and carbon dioxide levels, how SARS-CoV-2 spreads, the effectiveness of various types of masks, those who are most vulnerable to COVID-19, and whether our children should go back to school in the fall, and if so, what measures they should take.The authors' previous book, PLAGUE OF CORRUPTION, was the runaway science bestseller of 2020, and the authors bring that same passion and attention to detail to the mask question. As politicians and bureaucrats of all stripes are weighing in on this question, with some placing their cities and states under mandatory masking provisions, we need to understand the science behind their decisions. Are such measures a reasonable response to current circumstances, or is it a dramatic overreach, which in many cases might make the situation even worse? America desperately needs this public conversation to take place with the best science we have available. As Americans have always done during difficult times, we must summon the courage to have these challenging conversations.

The Water Secret: The Cellular Breakthrough to Look and Feel 10 Years Younger


Howard Murad - 2010
    Howard Murad, M.D., FAAD is one today's foremost authorities on health and skincare, and his philosophies have helped men and women around the world look and feel as young and healthy as possible. With The Water Secret, Dr. Murad shares a new, scientifically proven strategy, cultivated over years of practice and treating over 50,000 patients, to help you look and feel better from the inside out.The Water Secret will:• Reveal groundbreaking secrets to help you take years off your looks, feel better and healthier• Debunk health myths through cutting-edge research and tell the truth about how inflammation, hydration, and other factors really affect your health• Explain how damaged cells that leak water can sabotage your looks• Introduces an integrated, multidisciplinary "Inclusive Health" approach to help optimize cellular strength• Give you a complete 10-step action plan with recipes and meal plans to start you on the path to clear skin, fewer wrinkles, more energy, and better overall healthDiscover The Water Secret and learn to take control of the process of aging by improving the health of every cell in the body. Begin the program and you will see and feel the difference your healthy new lifestyle will make in as soon as one week!

Cell's Design


Fazale Rana - 2008
    Destined to be a landmark apologetic work, The Cell's Design explores the full scientific and theological impact of these discoveries. Instead of focusing on the inability of natural processes to generate life's chemical systems (as nearly all apologetics works do), Fazale Rana makes a positive case for life's supernatural basis by highlighting the many biochemical features that reflect the Creator's hallmark signature.This breakthrough work extends the case for design beyond irreducible complexity. These never-before-discussed evidences for design will evoke awe and amazement at God's creative majesty in the remarkable elegance of the cell's chemistry.

Revolution in a Bottle: From Worm Poop to a Garbage Empire That Is Redefining Green Business


Tom Szaky - 2009
    calls "The coolest little startup in America." While a freshman at Princeton, Tom Szaky co- founded a company that recycles garbage into worm poop, liquefies it, then packages it in used soda bottles, creating TerraCycle Plant Food. Five years later, this all-natural, highly effective fertilizer is available in every Home Depot, Target,Wal?Mart, and more than 3000 other locations. It's a thrilling entrepreneurial success story-and just the beginning of what makes Revolution in a Bottle fascinating. Szaky argues for a new approach to business, an "ecocapitalism" based on a "triple bottom line." Every business, he says, should aspire to be good for people, good for the environment, and (last but definitely not least) good for profits. He shows how the first two goals can help the third. Many companies brag about being environmentally-friendly. But no one does it as effectively as TerraCycle. Now they're also reusing garbage to create new products, from bird feeders to tote bags, and even engaging major companies like Kraft and General Mills to sponsor their waste streams. In the spirit of TerraCycle, this book will be printed on 100% recycled materials. About the Cover: This may look like a book jacket, but it's actually your very own upcycling container. Tom Szaky, founder of TerraCycle, is dedicated to eliminating the concept of waste. His firm works with other companies to collect and reuse nonrecyclable packaging and upcycle it into eco-friendly affordable products. And they want your help. One such company is Bear Naked(r), an all-natural food and lifestyle brand that has partnered with Terra-Cycle to operate the Bear Naked(r) Bag Brigade. This free program makes a donation to a school or nonprofit for every bag a participant collects. Now you can join in by using your book jacket as an envelope. See the back flap for instructions-it's easy. Then fill it with a used Bear Naked(r) granola bag and drop it in a mailbox to become a part of TerraCycle's eco- revolution! Bear Naked(r) will even donate $1 to plant a tree in American Forests, up to $5,000. Offer expires 12/31/09 or after the first 25,000 copies are sold, whichever comes first.

Fragile Species


Lewis Thomas - 1992
    The author of The Lives of a Cell and The Medusa and the Snail now raises challenging questions about some of the major issues of our time—AIDS, drug abuse, and aging.With extraordinary perception, author Lewis Thomas discusses topics such as evolutionary biology, the development of language, the therapeutic aspects of medicine, and his love for his profession.

Psycho Kitty?


Pam Johnson-Bennett - 1998
    Johnson-Bennett shares real cases to illustrate various problems and explains how she arrives at an appropriate solution through behavior modification. Her method requires a positive approach to correcting the behavior rather than punishment. She also uses interactive toys, which she believes helps not only to correct the behavior problem, but also to put the cat/owner relationship back in sync.

Rhythms of Life: The Biological Clocks that Control the Daily Lives of Every Living Thing


Russell Foster - 2004
    They discuss how scientists are working out the clockwork mechanisms and what governs them, and they describe how organisms measure different intervals of time, how they are adapted to various cycles, and how light coordinates the time within to the external world. They review problems that can be caused by malfunctioning biological clocks—including jet lag, seasonal affective disorder, and depression. And they warn that although new drugs are being promoted to allow us to stay awake for longer periods, a 24/7 lifestyle can have a harmful impact on our health, both as individuals and as a society.

The Deeper Genome: Why There Is More to the Human Genome Than Meets the Eye


John Parrington - 2015
    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.