Its effects on our view of life have been wide and deep. One of the most world-shaking books ever published, Charles Darwin's On the Origin of Species, first appeared in print over 130 years ago, and it touched off a debate that rages to this day.Every modern evolutionist turns to Darwin's work again and again. Current controversies in the life sciences very often have as their starting point some vagueness in Darwin's writings or some question Darwin was unable to answer owing to the insufficient biological knowledge available during his time. Despite the intense study of Darwin's life and work, however, many of us cannot explain his theories (he had several separate ones) and the evidence and reasoning behind them, nor do we appreciate the modifications of the Darwinian paradigm that have kept it viable throughout the twentieth century.Who could elucidate the subtleties of Darwin's thought and that of his contemporaries and intellectual heirs--A. R. Wallace, T. H. Huxley, August Weismann, Asa Gray--better than Ernst Mayr, a man considered by many to be the greatest evolutionist of the century? In this gem of historical scholarship, Mayr has achieved a remarkable distillation of Charles Darwin's scientific thought and his enormous legacy to twentieth-century biology. Here we have an accessible account of the revolutionary ideas that Darwin thrust upon the world. Describing his treatise as "one long argument," Darwin definitively refuted the belief in the divine creation of each individual species, establishing in its place the concept that all of life descended from a common ancestor. He proposed the idea that humans were not the special products of creation but evolved according to principles that operate everywhere else in the living world; he upset current notions of a perfectly designed, benign natural world and substituted in their place the concept of a struggle for survival; and he introduced probability, chance, and uniqueness into scientific discourse.This is an important book for students, biologists, and general readers interested in the history of ideas--especially ideas that have radically altered our worldview. Here is a book by a grand master that spells out in simple terms the historical issues and presents the controversies in a manner that makes them understandable from a modern perspective.

    For many the topic was seen as being fact-rich but understanding-poor, smelly, and so far removed from the real world of events and pleasures that there seemed little point, except for the most introverted, in coming to terms with its grubby concepts, spells, recipes, and rules. Peter Atkins wants to change all that. In What is Chemistry? he encourages us to look at chemistry anew, through a chemist's eyes, to understand its central concepts and to see how it contributes not only towards our material comfort, but also to human culture. He shows how chemistry provides the infrastructure of our world, through the chemical industry, the fuels of heating, power generation, and transport, as well as the fabrics of our clothing and furnishings. By considering the remarkable achievements that chemistry has made, and examining its place between both physics and biology, Atkins presents a fascinating, clear, and rigorous exploration of the world of chemistry -- its structure, core concepts, and contributions.

    . . a great read,"" and that has been praised as ""a delightful dance through science"" ("New York Times "bestselling author Mark Hyman, M.D.) and as a ""remarkable and insightful book [that] offers you the chance to achieve the best health of your life"" (Mark Liponis, M.D., Medical Director, Canyon Ranch).Written by bestselling author Gene Stone, "The Secrets of People Who Never Get Sick "arose from his desire to discover what might actually prevent him from getting sick himself. This book, the result of that exploration, tells the stories of twenty-five people who each possess a different secret of excellent health--a secret that makes sense and that Stone discovered has a true scientific underpinning. There are food secrets--why to take garlic and vitamin C, eat more probiotics, becomea vegan, drink a tonic of brewer's yeast. Exercise secrets--the benefits of lifting weights, the power of stretching. Environmental secrets--living in a Blue Zone, understanding the value of germs. Emotional secrets--seek out and stay in touch with friends, cultivate your spirituality. Physical secrets--nap more, take cold showers in the morning. And the wisdom that goes back generations: Yes, chicken soup works.The stories make it personal, the research makes it real, and the do-it-yourself information shows how to integrate each secret into your own life, and become the next person who never gets sick.

    But what’s the best way to feed our all-important microbiome—and what is a microbiome, anyway? In this engaging and eye-opening book, science journalist Katherine Harmon Courage investigates these questions, presenting a deep dive into the ancient food traditions and the latest research for maintaining a healthy gut. Courage’s insights include: • Meet your microbiome: What it is, how it works, and why it’s essential for our immune system–and overall health • Gut-friendly food traditions: A guided tour of artisanal makers of yogurt, kimchi, kefir, kombucha, olives, cocoa, and other vibrant, ancient foods from around the world that feed our microbiome (along with simple recipes for curious at-home cooks) • Cutting-edge science: A first-hand look at some of the top lab facilities where microbiologists are working to better understand the human gut and how to feed it for good health Equal parts science explainer, culinary investigation, and global roadmap for healthy eating, Cultured offers a wealth of information for anyone interested in making smart food choices in our not-so-gut-friendly modern world.PRAISE“Deeply researched but conversational and even funny, Cultured is the guide we need to make sense of the hope and hype of microbiome science and what it means for our everyday lives.” –Maryn McKenna, author of Big Chicken, Superbug, and Beating Back the Devil“This enthralling book sounds the clarion call to end the senseless onslaught of warfare waged against our microbial symbionts. It is time to embrace the world within us and feed the ferment that keeps us happy and healthy.” –Ken Albala, Professor of History University of the Pacific

    Paul Colinvaux takes a penetrating look at the science of ecology, bringing to his subject both profound knowledge and an enthusiasm that will encourage a greater understanding of the environment and of the efforts of those who seek to preserve it.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    In many circles this disease, still known as Yuppi Flu, is dismissed as a psychological aberration. For the nearly two million people who have endured its traumatic and very real debilitating physical effects, however, Chronic Fatigue Syndrome is no joke.

    Open Source has grabbed the computer industry's attention. Netscape has opened the source code to Mozilla; IBM supports Apache; major database vendors haved ported their products to Linux. As enterprises realize the power of the open-source development model, Open Source is becoming a viable mainstream alternative to commercial software.Now in Open Sources, leaders of Open Source come together for the first time to discuss the new vision of the software industry they have created. The essays in this volume offer insight into how the Open Source movement works, why it succeeds, and where it is going.For programmers who have labored on open-source projects, Open Sources is the new gospel: a powerful vision from the movement's spiritual leaders. For businesses integrating open-source software into their enterprise, Open Sources reveals the mysteries of how open development builds better software, and how businesses can leverage freely available software for a competitive business advantage.The contributors here have been the leaders in the open-source arena:Brian Behlendorf (Apache) Kirk McKusick (Berkeley Unix) Tim O'Reilly (Publisher, O'Reilly & Associates) Bruce Perens (Debian Project, Open Source Initiative) Tom Paquin and Jim Hamerly (mozilla.org, Netscape) Eric Raymond (Open Source Initiative) Richard Stallman (GNU, Free Software Foundation, Emacs) Michael Tiemann (Cygnus Solutions) Linus Torvalds (Linux) Paul Vixie (Bind) Larry Wall (Perl) This book explains why the majority of the Internet's servers use open- source technologies for everything from the operating system to Web serving and email. Key technology products developed with open-source software have overtaken and surpassed the commercial efforts of billion dollar companies like Microsoft and IBM to dominate software markets. Learn the inside story of what led Netscape to decide to release its source code using the open-source mode. Learn how Cygnus Solutions builds the world's best compilers by sharing the source code. Learn why venture capitalists are eagerly watching Red Hat Software, a company that gives its key product -- Linux -- away.For the first time in print, this book presents the story of the open- source phenomenon told by the people who created this movement.Open Sources will bring you into the world of free software and show you the revolution.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    The most up-to-date and beautifully illustrated text on the market, it has a strong molecular and cellular approach, firmly relating the molecular and cellular biological underpinnings of physiology to the study of human physiology and disease. Contributions from leading physiologists ensure authoritative, cutting-edge information, and thorough and consistent editing have produced a readable and student-friendly text.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

    In The Woman with a Worm in Her Head, Dr. Pamela Nagami reveals-through real-life cases-the sobering facts about some of the world's most horrific diseases: the warning signs, the consequences, treatments, and most compellingly, what it feels like to make medical and ethical decisions that can mean the difference between life and death.Unfailingly precise, calmly instructive, and absolutely engrossing, The Woman with the Worm in Her Head offers both useful information and enjoyable reading.

    Coated in red dust, the terrain is bewilderingly empty. And yet multiple spacecraft are circling Mars, sweeping over Terra Sabaea, Syrtis Major, the dunes of Elysium, and Mare Sirenum—on the brink, perhaps, of a staggering find, one that would inspire humankind as much as any discovery in the history of modern science.In this beautifully observed, deeply personal book, Georgetown scientist Sarah Stewart Johnson tells the story of how she and other researchers have scoured Mars for signs of life, transforming the planet from a distant point of light into a world of its own.Johnson’s fascination with Mars began as a child in Kentucky, turning over rocks with her father and looking at planets in the night sky. She now conducts fieldwork in some of Earth’s most hostile environments, such as the Dry Valleys of Antarctica and the salt flats of Western Australia, developing methods for detecting life on other worlds. Here, with poetic precision, she interlaces her own personal journey—as a female scientist and a mother—with tales of other seekers, from Percival Lowell, who was convinced that a utopian society existed on Mars, to Audouin Dollfus, who tried to carry out astronomical observations from a stratospheric balloon. In the process, she shows how the story of Mars is also a story about Earth: This other world has been our mirror, our foil, a telltale reflection of our own anxieties and yearnings.Empathetic and evocative, The Sirens of Mars offers an unlikely natural history of a place where no human has ever set foot, while providing a vivid portrait of our quest to defy our isolation in the cosmos.