Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

     Drawing from a lifetime of lessons learned, seven-time Emmy winner Betty White's wit and wisdom take center stage as she tackles topics like friendship, romantic love, aging, television, fans, love for animals, and the brave new world of celebrity. If You Ask Me mixes her thoughtful observations with humorous stories from a seven- decade career in Hollywood. Longtime fans and new fans alike will relish Betty's candid take on everything from her rumored crush on Robert Redford (true) to her beauty regimen ("I have no idea what color my hair is and I never intend to find out") to the Facebook campaign that helped persuade her to host Saturday Night Live despite her having declined the hosting job three times already. Featuring all-new material, with a focus on the past fifteen years of her life, If You Ask Me is funny, sweet, and to the point-just like Betty White.

    A sensational disappearance that made headlines around the world. A quest for truth that leads to death, madness or disappearance for those who seek to solve it. The Lost City of Z is a blockbuster adventure narrative about what lies beneath the impenetrable jungle canopy of the Amazon.After stumbling upon a hidden trove of diaries, New Yorker writer David Grann set out to solve "the greatest exploration mystery of the 20th century": What happened to the British explorer Percy Fawcett & his quest for the Lost City of Z?In 1925, Fawcett ventured into the Amazon to find an ancient civilization, hoping to make one of the most important discoveries in history. For centuries Europeans believed the world's largest jungle concealed the glittering kingdom of El Dorado. Thousands had died looking for it, leaving many scientists convinced that the Amazon was truly inimical to humans. But Fawcett, whose daring expeditions inspired Conan Doyle's The Lost World, had spent years building his scientific case. Captivating the imagination of millions round the globe, Fawcett embarked with his 21-year-old son, determined to prove that this ancient civilisation--which he dubbed Z--existed. Then his expedition vanished. Fawcett's fate, & the tantalizing clues he left behind about Z, became an obsession for hundreds who followed him into the uncharted wilderness. For decades scientists & adventurers have searched for evidence of Fawcett's party & the lost City of Z. Countless have perished, been captured by tribes or gone mad. As Grann delved ever deeper into the mystery surrounding Fawcett's quest, & the greater mystery of what lies within the Amazon, he found himself, like the generations who preceded him, being irresistibly drawn into the jungle's green hell. His quest for the truth & discoveries about Fawcett's fate & Z form the heart of this complexly enthralling narrative.

    But along the way, the feminist pioneer's searing dissents and steely strength have inspired millions. Notorious RBG: The Life and Times of Ruth Bader Ginsburg, created by the young lawyer who began the Internet sensation and an award-winning journalist, takes you behind the myth for an intimate, irreverent look at the justice's life and work. As America struggles with the unfinished business of gender equality and civil rights, Ginsburg stays fierce. And if you don't know, now you know.

    It continued in Moscow, where Browder made his fortune heading the largest investment fund in Russia after the Soviet Union's collapse. But when he exposed the corrupt oligarchs who were robbing the companies in which he was investing, Vladimir Putin turned on him and, in 2005, had him expelled from Russia. In 2007, a group of law enforcement officers raided Browder's offices in Moscow and stole $230 million of taxes that his fund's companies had paid to the Russian government. Browder's attorney Sergei Magnitsky investigated the incident and uncovered a sprawling criminal enterprise. A month after Sergei testified against the officials involved, he was arrested and thrown into pre-trial detention, where he was tortured for a year. On November 16, 2009, he was led to an isolation chamber, handcuffed to a bedrail, and beaten to death by eight guards in full riot gear. Browder glimpsed the heart of darkness, and it transformed his life: he embarked on an unrelenting quest for justice in Sergei's name, exposing the towering cover-up that leads right up to Putin. A financial caper, a crime thriller, and a political crusade, Red Notice is the story of one man taking on overpowering odds to change the world.

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    <br><br>Part Tuscan idyll and part cautionary tale, Wendy Laird’s latest Kindle Single tells the flip-side story of expat existence, what it takes to make it happen, and how a life on a well-mapped trajectory can veer off course in the process. Laird’s beautiful prose and acerbic wit keep the book, if not her own agenda, on the right track.

    Fans around the world are drawn to Her Grace’s voice, her wit, her life-affirming love for all humanity, and the fun and friendship of the community that’s sprung up around her.

    As First Lady of the United States of America—the first African American to serve in that role—she helped create the most welcoming and inclusive White House in history, while also establishing herself as a powerful advocate for women and girls in the U.S. and around the world, dramatically changing the ways that families pursue healthier and more active lives, and standing with her husband as he led America through some of its most harrowing moments. Along the way, she showed us a few dance moves, crushed Carpool Karaoke, and raised two down-to-earth daughters under an unforgiving media glare. In her memoir, a work of deep reflection and mesmerizing storytelling, Michelle Obama invites readers into her world, chronicling the experiences that have shaped her—from her childhood on the South Side of Chicago to her years as an executive balancing the demands of motherhood and work, to her time spent at the world’s most famous address. With unerring honesty and lively wit, she describes her triumphs and her disappointments, both public and private, telling her full story as she has lived it—in her own words and on her own terms. Warm, wise, and revelatory, Becoming is the deeply personal reckoning of a woman of soul and substance who has steadily defied expectations—and whose story inspires us to do the same.

    But even before that, she stood out in her conservative oil town. She was a tomboy who was also intellectually curious and artistic. By the time she reached high school, she had drawn the scorn of her peers for her embrace of the Beats and her racially progressive views. Her parents doted on her in many ways, but were ultimately put off by her repeated acts of defiance. Janis Joplin has passed into legend as a brash, impassioned soul doomed by the pain that produced one of the most extraordinary voices in rock history. But in these pages, Holly George-Warren provides a revelatory and deeply satisfying portrait of a woman who wasn’t all about suffering. Janis was a perfectionist: a passionate, erudite musician who was born with talent but also worked exceptionally hard to develop it. She was a woman who pushed the boundaries of gender and sexuality long before it was socially acceptable. She was a sensitive seeker who wanted to marry and settle down—but couldn’t, or wouldn’t. She was a Texan who yearned to flee Texas but could never quite get away—even after becoming a countercultural icon in San Francisco. Written by one of the most highly regarded chroniclers of American music history, and based on unprecedented access to Janis Joplin’s family, friends, band mates, archives, and long-lost interviews, Janis is a complex, rewarding portrait of a remarkable artist finally getting her due.

    The book soared to the top of bestseller lists internationally, igniting global conversations about women and ambition. Sandberg packed theatres, dominated opinion pages, appeared on every major television show and on the cover of Time magazine, and sparked ferocious debate about women and leadership. Ask most women whether they have the right to equality at work and the answer will be a resounding yes, but ask the same women whether they'd feel confident asking for a raise, a promotion, or equal pay, and some reticence creeps in. The statistics, although an improvement on previous decades, are certainly not in women's favour – of 197 heads of state, only twenty-two are women. Women hold just 20 percent of seats in parliaments globally, and in the world of big business, a meagre eighteen of the Fortune 500 CEOs are women. In Lean In, Sheryl Sandberg – Facebook COO and one of Fortune magazine's Most Powerful Women in Business – draws on her own experience of working in some of the world's most successful businesses and looks at what women can do to help themselves, and make the small changes in their life that can effect change on a more universal scale.

    Jenny Lawson realized that the most mortifying moments of our lives—the ones we’d like to pretend never happened—are in fact the ones that define us. Lawson takes readers on a hilarious journey recalling her bizarre upbringing in rural Texas, her devastatingly awkward high school years, and her relationship with her long-suffering husband, Victor. Chapters include: “Stanley the Magical, Talking Squirrel”; “A Series of Angry Post-It Notes to My Husband”; “My Vagina Is Fine. Thanks for Asking”; “And Then I Snuck a Dead Cuban Alligator on an Airplane.” Pictures with captions (no one would believe these things without proof) accompany the text.

    This feeling only deepened when his family moved from Japan to North Korea when Ishikawa was just thirteen years old, and unwittingly became members of the lowest social caste. His father, himself a Korean national, was lured to the new Communist country by promises of abundant work, education for his children, and a higher station in society. But the reality of their new life was far from utopian.In this memoir translated from the original Japanese, Ishikawa candidly recounts his tumultuous upbringing and the brutal thirty-six years he spent living under a crushing totalitarian regime, as well as the challenges he faced repatriating to Japan after barely escaping North Korea with his life. A River in Darkness is not only a shocking portrait of life inside the country but a testament to the dignity—and indomitable nature—of the human spirit