The First Shots: The Epic Rivalries and Heroic Science Behind the Race to the Coronavirus Vaccine


Brendan Borrell - 2021
    Chaotic politics. Billionaire entrepreneurs. Award-winning journalist Brendan Borrell brings the defining story of our times alive through compulsively readable, first-time reporting on the players leading the fight against a vicious virus. The First Shots, soon to be the subject of an HBO limited series with superstar director and producer Adam McKay (Succession, Vice, The Big Short), draws on exclusive, high-level access to weave together the intense vaccine-race conflicts among hard-driving, heroic scientists and the epic rivalries among Washington power players that shaped 18 months of fear, resolve, and triumph. From infectious disease expert Michael Callahan, an American doctor secretly on the ground in Wuhan in January 2020 to gauge the terrifying ravages of Disease X; to Robert (Dr. Bob) Kadlec, one of Operation Warp Speed’s architects, whose audacious plans for the American people run straight into the buzz saw of the Trump White House factions; to Stéphane Bancel of upstart Moderna Therapeutics going toe-to-toe with pharma behemoth Pfizer, The First Shots lays bare, in a way we have not seen, the full stunning story behind the medical science “moon shot” of our lifetimes.

Future Crimes


Marc Goodman - 2015
    Hackers can activate baby monitors to spy on families, thieves are analyzing social media posts to plot home invasions, and stalkers are exploiting the GPS on smart phones to track their victims’ every move. We all know today’s criminals can steal identities, drain online bank accounts, and wipe out computer servers, but that’s just the beginning. To date, no computer has been created that could not be hacked—a sobering fact given our radical dependence on these machines for everything from our nation’s power grid to air traffic control to financial services.      Yet, as ubiquitous as technology seems today, just over the horizon is a tidal wave of scientific progress that will leave our heads spinning. If today’s Internet is the size of a golf ball, tomorrow’s will be the size of the sun. Welcome to the Internet of Things, a living, breathing, global information grid where every physical object will be online. But with greater connections come greater risks. Implantable medical devices such as pacemakers can be hacked to deliver a lethal jolt of electricity and a car’s brakes can be disabled at high speed from miles away. Meanwhile, 3-D printers can produce AK-47s, bioterrorists can download the recipe for Spanish flu, and cartels are using fleets of drones to ferry drugs across borders.     With explosive insights based upon a career in law enforcement and counterterrorism, Marc Goodman takes readers on a vivid journey through the darkest recesses of the Internet. Reading like science fiction, but based in science fact, Future Crimes explores how bad actors are primed to hijack the technologies of tomorrow, including robotics, synthetic biology, nanotechnology, virtual reality, and artificial intelligence. These fields hold the power to create a world of unprecedented abundance and prosperity. But the technological bedrock upon which we are building our common future is deeply unstable and, like a house of cards, can come crashing down at any moment.     Future Crimes provides a mind-blowing glimpse into the dark side of technological innovation and the unintended consequences of our connected world. Goodman offers a way out with clear steps we must take to survive the progress unfolding before us. Provocative, thrilling, and ultimately empowering, Future Crimes will serve as an urgent call to action that shows how we can take back control over our own devices and harness technology’s tremendous power for the betterment of humanity—before it’s too late.From the Hardcover edition.

The Patient Will See You Now: The Future of Medicine is in Your Hands


Eric J. Topol - 2015
    You'll make an appointment months in advance. You'll probably wait for several hours until you hear "the doctor will see you now"—but only for fifteen minutes! Then you'll wait even longer for lab tests, the results of which you'll likely never see, unless they indicate further (and more invasive) tests, most of which will probably prove unnecessary (much like physicals themselves). And your bill will be astronomical.In The Patient Will See You Now, Eric Topol, one of the nation’s top physicians, shows why medicine does not have to be that way. Instead, you could use your smartphone to get rapid test results from one drop of blood, monitor your vital signs both day and night, and use an artificially intelligent algorithm to receive a diagnosis without having to see a doctor, all at a small fraction of the cost imposed by our modern healthcare system.The change is powered by what Topol calls medicine's "Gutenberg moment." Much as the printing press took learning out of the hands of a priestly class, the mobile internet is doing the same for medicine, giving us unprecedented control over our healthcare. With smartphones in hand, we are no longer beholden to an impersonal and paternalistic system in which "doctor knows best." Medicine has been digitized, Topol argues; now it will be democratized. Computers will replace physicians for many diagnostic tasks, citizen science will give rise to citizen medicine, and enormous data sets will give us new means to attack conditions that have long been incurable. Massive, open, online medicine, where diagnostics are done by Facebook-like comparisons of medical profiles, will enable real-time, real-world research on massive populations. There's no doubt the path forward will be complicated: the medical establishment will resist these changes, and digitized medicine inevitably raises serious issues surrounding privacy. Nevertheless, the result—better, cheaper, and more human health care—will be worth it.Provocative and engrossing, The Patient Will See You Now is essential reading for anyone who thinks they deserve better health care. That is, for all of us.

Skunk Works: A Personal Memoir of My Years at Lockheed


Ben R. Rich - 1994
    As recounted by Ben Rich, the operation's brilliant boss for nearly two decades, the chronicle of Lockheed's legendary Skunk Works is a drama of cold war confrontations and Gulf War air combat, of extraordinary feats of engineering & achievement against fantastic odds. Here are up-close portraits of the maverick band of scientists & engineers who made the Skunk Works so renowned. Filled with telling personal anecdotes & high adventure, with narratives from the CIA & from Air Force pilots who flew the many classified, risky missions, this book is a portrait of the most spectacular aviation triumphs of the 20th century.

Zero: The Biography of a Dangerous Idea


Charles Seife - 2000
    For centuries, the power of zero savored of the demonic; once harnessed, it became the most important tool in mathematics. Zero follows this number from its birth as an Eastern philosophical concept to its struggle for acceptance in Europe and its apotheosis as the mystery of the black hole. Today, zero lies at the heart of one of the biggest scientific controversies of all time, the quest for the theory of everything. Elegant, witty, and enlightening, Zero is a compelling look at the strangest number in the universe and one of the greatest paradoxes of human thought.

Distrust That Particular Flavor


William Gibson - 2012
    "Wired" magazine sent him to Singapore to report on one of the world's most buttoned-up states. "The New York Times Magazine" asked him to describe what was wrong with the Internet. Rolling Stone published his essay on the ways our lives are all "soundtracked" by the music and the culture around us. And in a speech at the 2010 Book Expo, he memorably described the interactive relationship between writer and reader.These essays and articles have never been collected-until now. Some have never appeared in print at all. In addition, "Distrust That Particular Flavor" includes journalism from small publishers, online sources, and magazines no longer in existence. This volume will be essential reading for any lover of William Gibson's novels. "Distrust That Particular Flavor" offers readers a privileged view into the mind of a writer whose thinking has shaped not only a generation of writers but our entire culture.

The Hidden Life of Trees


Peter Wohlleben - 2015
    Much like human families, tree parents live together with their children, communicate with them, and support them as they grow, sharing nutrients with those who are sick or struggling and creating an ecosystem that mitigates the impact of extremes of heat and cold for the whole group. As a result of such interactions, trees in a family or community are protected and can live to be very old. In contrast, solitary trees, like street kids, have a tough time of it and in most cases die much earlier than those in a group.Drawing on groundbreaking new discoveries, Wohlleben presents the science behind the secret and previously unknown life of trees and their communication abilities; he describes how these discoveries have informed his own practices in the forest around him. As he says, a happy forest is a healthy forest, and he believes that eco-friendly practices not only are economically sustainable but also benefit the health of our planet and the mental and physical health of all who live on Earth.

The Search for Exoplanets: What Astronomers Know


Joshua N. Winn - 2015
    Thanks to advances in technology and clever new uses of existing data, now we know that planetary systems and possibly even a new Earth can be found throughout galaxies near and far.We are living during a new golden age of planetary discovery, with the prospect of finding many worlds like Earth. Most of the thousands of planets we've detected can't be imaged directly, but researchers are able to use subtle clues obtained in ingenious ways to assemble an astonishing picture of planetary systems far different from our own. We are in the midst of an astronomical revolution, comparable to the Copernican revolution that established our current view of the solar system - and we invite you to take part.Embark on this unrivaled adventure in 24 lectures by a veteran planet hunter. Designed for everyone from armchair explorers to serious skywatchers, The Search for Exoplanets follows the numerous twists and turns in the hunt for exoplanets - the false starts, the sudden breakthroughs, and the extraordinary discoveries. Explore systems containing super-Earths, mini-Neptunes, lava worlds, and even stranger worlds. You also get behind-the-scenes information on the techniques astronomers used to find evidence of planets at mind-boggling distances from our home base. Learn how astronomers determine how many planets are in a system as well as how large they are and the characteristics of their atmospheres. You will feel like Dr. Watson in the presence of Sherlock Holmes as Professor Winn extracts a wealth of information from a spectrum, a light graph, a diffraction pattern, and other subtle clues.©2015 The Teaching Company, LLC (P)2015 The Great Courses

Physics for Future Presidents: The Science Behind the Headlines


Richard A. Muller - 2006
    “A marvelously readable and level-headed explanation of basic science and how it relates to the issues.” —John Tierney, New York TimesThis is “must-have” information for all presidents—and citizens—of the twenty-first century: Is Iran’s nascent nuclear capability a genuine threat to the West? Are biochemical weapons likely to be developed by terrorists? Are there viable alternatives to fossil fuels that should be nurtured and supported by the government? Should nuclear power be encouraged? Can global warming be stopped?

Weird Life: The Search for Life That Is Very, Very Different from Our Own


David Toomey - 2013
    There were bacteria in volcanic hydrothermal vents on the ocean floor, single-celled algae in Antarctic ice floes, and fungi in the cooling pools of nuclear reactors.But might there be life stranger than the most extreme extremophile? Might there be, somewhere, another kind of life entirely? In fact, scientists have hypothesized life that uses ammonia instead of water, life based not in carbon but in silicon, life driven by nuclear chemistry, and life whose very atoms are unlike those in life we know. In recent years some scientists have begun to look for the tamer versions of such life on rock surfaces in the American Southwest, in a “shadow biosphere” that might impinge on the known biosphere, and even deep within human tissue. They have also hypothesized more radical versions that might survive in Martian permafrost, in the cold ethylene lakes on Saturn’s moon Titan, and in the hydrogen-rich atmospheres of giant planets in other solar systems. And they have imagined it in places off those worlds: the exotic ices in comets, the vast spaces between the stars, and—strangest of all—parallel universes.Distilling complex science in clear and lively prose, David Toomey illuminates the research of the biological avant-garde and describes the workings of weird organisms in riveting detail. His chapters feature an unforgettable cast of brilliant scientists and cover everything from problems with our definitions of life to the possibility of intelligent weird life. With wit and understanding that will delight scientists and lay readers alike, Toomey reveals how our current knowledge of life forms may account for only a tiny fraction of what’s really out there.

A Brief History of Everyone Who Ever Lived: The Stories in Our Genes


Adam Rutherford - 2016
    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

The Last Days of Night


Graham Moore - 2016
    Gas lamps still flicker in the city streets, but the miracle of electric light is in its infancy. The person who controls the means to turn night into day will make history--and a vast fortune. A young untested lawyer named Paul Cravath, fresh out of Columbia Law School, takes a case that seems impossible to win. Paul's client, George Westinghouse, has been sued by Thomas Edison over a billion-dollar question: Who invented the light bulb and holds the right to power the country? The case affords Paul entry to the heady world of high society--the glittering parties in Gramercy Park mansions, and the more insidious dealings done behind closed doors. The task facing him is beyond daunting. Edison is a wily, dangerous opponent with vast resources at his disposal--private spies, newspapers in his pocket, and the backing of J. P. Morgan himself. Yet this unknown lawyer shares with his famous adversary a compulsion to win at all costs. How will he do it?In obsessive pursuit of victory, Paul crosses paths with Nikola Tesla, an eccentric, brilliant inventor who may hold the key to defeating Edison, and with Agnes Huntington, a beautiful opera singer who proves to be a flawless performer on stage and off. As Paul takes greater and greater risks, he'll find that everyone in his path is playing their own game, and no one is quite who they seem.

The Smallest Lights in the Universe: A Memoir


Sara Seager - 2020
    But with the unexpected death of her husband, her life became an empty, lightless space. Suddenly she was the single mother of two young boys, a widow at forty, clinging to three crumpled pages of instructions her husband had written for things like grocery shopping--things he had done while she did pioneering work as a planetary scientist at MIT. She became painfully conscious of her Asperger's, which before losing her husband had felt more like background noise. She felt, for the first time, alone in the universe.In this probing, invigoratingly honest memoir, Seager tells the story of how, as she stumblingly navigated the world of grief, she also kept looking for other worlds. She continues to develop groundbreaking projects, such as the Starshade, a sunflower-shaped instrument that, when launched into space, unfurls itself so as to block planet-obscuring starlight, and she takes solace in the alien beauty of exoplanets. At the same time, she discovers what feels every bit as wondrous: other people, reaching out across the space of her grief. Among them are the Widows of Concord, a group of women offering consolation and advice; and her beloved sons, Max and Alex. Most unexpected of all, there is another kind of one-in-a-billion match with an amateur astronomer.Equally attuned to the wonders of deep space and human connection, The Smallest Lights in the Universe is its own light in the dark.

The Master Switch: The Rise and Fall of Information Empires


Tim Wu - 2010
    With all our media now traveling a single network, an unprecedented potential is building for centralized control over what Americans see and hear. Could history repeat itself with the next industrial consolidation? Could the Internet—the entire flow of American information—come to be ruled by one corporate leviathan in possession of “the master switch”? That is the big question of Tim Wu’s pathbreaking book.As Wu’s sweeping history shows, each of the new media of the twentieth century—radio, telephone, television, and film—was born free and open. Each invited unrestricted use and enterprising experiment until some would-be mogul battled his way to total domination. Here are stories of an uncommon will to power, the power over information: Adolph Zukor, who took a technology once used as commonly as YouTube is today and made it the exclusive prerogative of a kingdom called Hollywood . . . NBC’s founder, David Sarnoff, who, to save his broadcast empire from disruptive visionaries, bullied one inventor (of electronic television) into alcoholic despair and another (this one of FM radio, and his boyhood friend) into suicide . . . And foremost, Theodore Vail, founder of the Bell System, the greatest information empire of all time, and a capitalist whose faith in Soviet-style central planning set the course of every information industry thereafter.Explaining how invention begets industry and industry begets empire—a progress often blessed by government, typically with stifling consequences for free expression and technical innovation alike—Wu identifies a time-honored pattern in the maneuvers of today’s great information powers: Apple, Google, and an eerily resurgent AT&T. A battle royal looms for the Internet’s future, and with almost every aspect of our lives now dependent on that network, this is one war we dare not tune out.Part industrial exposé, part meditation on what freedom requires in the information age, The Master Switch is a stirring illumination of a drama that has played out over decades in the shadows of our national life and now culminates with terrifying implications for our future.

The Unthinkable: Who Survives When Disaster Strikes - and Why


Amanda Ripley - 2008
    Today, nine out of ten Americans live in places at significant risk of earthquakes, hurricanes, tornadoes, terrorism, or other disasters. Tomorrow, some of us will have to make split-second choices to save ourselves and our families. How will we react? What will it feel like? Will we be heroes or victims? Will our upbringing, our gender, our personality–anything we’ve ever learned, thought, or dreamed of–ultimately matter?    Amanda Ripley, an award-winning journalist for Time magazine who has covered some of the most devastating disasters of our age, set out to discover what lies beyond fear and speculation. In this magnificent work of investigative journalism, Ripley retraces the human response to some of history’s epic disasters, from the explosion of the Mont Blanc munitions ship in 1917–one of the biggest explosions before the invention of the atomic bomb–to a plane crash in England in 1985 that mystified investigators for years, to the journeys of the 15,000 people who found their way out of the World Trade Center on September 11, 2001. Then, to understand the science behind the stories, Ripley turns to leading brain scientists, trauma psychologists, and other disaster experts, formal and informal, from a Holocaust survivor who studies heroism to a master gunfighter who learned to overcome the effects of extreme fear. Finally, Ripley steps into the dark corners of her own imagination, having her brain examined by military researchers and experiencing through realistic simulations what it might be like to survive a plane crash into the ocean or to escape a raging fire.     Ripley comes back with precious wisdom about the surprising humanity of crowds, the elegance of the brain’s fear circuits, and the stunning inadequacy of many of our evolutionary responses. Most unexpectedly, she discovers the brain’s ability to do much, much better, with just a little help.The Unthinkable escorts us into the bleakest regions of our nightmares, flicks on a flashlight, and takes a steady look around. Then it leads us home, smarter and stronger than we were before.