In The Woman with a Worm in Her Head, Dr. Pamela Nagami reveals-through real-life cases-the sobering facts about some of the world's most horrific diseases: the warning signs, the consequences, treatments, and most compellingly, what it feels like to make medical and ethical decisions that can mean the difference between life and death.Unfailingly precise, calmly instructive, and absolutely engrossing, The Woman with the Worm in Her Head offers both useful information and enjoyable reading.

    Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn't know it then, but dementia was starting to take hold. In 2014, at age fifty-eight, she was diagnosed with young-onset Alzheimer's.Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off. What lay ahead of her after the diagnosis was scary and unknowable, but Mitchell was determined and resourceful, and she vowed to outwit the disease for as long as she could.As Mitchell learned to embrace her new life, she began to see her condition as a gift, a chance to experience the world with fresh eyes and to find her own way to make a difference. Even now, her sunny outlook persists: She devotes her time to educating doctors, caregivers, and other people living with dementia, helping to reduce the stigma surrounding this insidious disease.Still living independently, Mitchell now uses Post-it notes and technology to remind her of her routines and has created a "memory room" where she displays photos--with labels--of her daughters, friends, and special places. It is a room where she feels calm and happy, especially on days when the mist descends.

    Dr. Manheimer describes the plights of twelve very different patients--from dignitaries at the nearby UN, to supermax prisoners at Riker's Island, to illegal immigrants, and Wall Street tycoons.Manheimer was not only the medical director of the country's oldest public hospital for over 13 years, but he was also a patient. As the book unfolds, the narrator is diagnosed with cancer, and he is forced to wrestle with the end of his own life even as he struggles to save the lives of others.

    As the cancer progressed and was treated, the author experienced behavioral and cognitive symptoms connected to a range of mental disorders, including her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, recalled her experience and, through her knowledge of neuroscience, identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist McArdle, shows that strength and courage but also a encouraging support network are vital to recovery

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Years of listening to other people's stories of going through tough times, hoping to overcome difficult odds, or trying to find a way to make a difference in the world brought Edward Grinnan to the undersanding that personal change is vital to achieving success. In each chaper of this book, he weaves the tales of other people with his own story to reveal how each of us can learn about the keys to powerful personal change. He shows these principles at work in his own personal struggle with alcoholism, and how he has learned through his own missteps to accept change and become the person he was meant to be.

     In this deeply funny (and, no kidding, wise and poignant) book, Rakoff examines the realities of our sunny,  gosh­ everyone-can-be-a-star contemporary culture and finds that, pretty much as a universal rule, the best is not yet to come, adversity will triumph, justice will not be served, and your dreams won’t come true. The book ranges from the personal to the universal, combining stories from Rakoff’s reporting and accounts of his own experi­ences: the moment when being a tiny child no longer meant adults found him charming but instead meant other children found him a fun target; the perfect late evening in Manhattan when he was young and the city seemed to brim with such pos­sibility that the street shimmered in the moonlight—as he drew closer he realized the streets actually flickered with rats in a feeding frenzy. He also weaves in his usual brand Oscar Wilde–worthy cultural criticism (the tragedy of Hollywood’s Walk of Fame, for instance). Whether he’s lacerating the musical Rent for its cutesy depic­tion of AIDS or dealing with personal tragedy, his sharp obser­vations and humorist’s flair for the absurd will have you positively reveling in the power of negativity.

    Of course, in middle school and high school, almost everyone is an outsider: the nerds, the new girls, the band geeks, the loners; even the "popular" cheerleaders. Alexandra Robbins' The Geeks Shall Inherit the Earth takes us inside the hallways of real schools to show us how shifting cliques and permanent marginalization affect children. Following individual students over the course of a year, she tracks the plight and possibilities of self-confessed nerds, freaks, punks, Goths, and weirdos. Her central message is heartening: Our increasingly homogenized society ultimately needs and welcomes the cafeteria fringe.

    We have an illusion that someone from the outside can heal us. If anybody can heal us, it is only ourselves. It will take centuries for science to learn the hopelessness of the attempt to push the everchanging human body into frames of scientific theories. But it is possible to know what we need to do here and now for our health. It is possible to learn to listen to our body's voice.

    How does life begin? What does it mean? What happens when we die? “All anyone can do is ask,” Lepore writes. “That's why any history of ideas about life and death has to be, like this book, a history of curiosity.” Lepore starts that history with the story of a seventeenth-century Englishman who had the idea that all life begins with an egg and ends it with an American who, in the 1970s, began freezing the dead. In between, life got longer, the stages of life multiplied, and matters of life and death moved from the library to the laboratory, from the humanities to the sciences. Lately, debates about life and death have determined the course of American politics. Each of these debates has a history. Investigating the surprising origins of the stuff of everyday life—from board games to breast pumps—Lepore argues that the age of discovery, Darwin, and the Space Age turned ideas about life on earth topsy-turvy. “New worlds were found,” she writes, and “old paradises were lost.” As much a meditation on the present as an excavation of the past, The Mansion of Happiness is delightful, learned, and altogether beguiling.

    Last Wish is an intimate, fiercely honest memoir of a daughter's struggle to come to terms with her terminally ill mother's decision to die. More than a examination of the ethical, spiritual, and technical aspects of assisted suicide, Last Wish is also a celebration of Rollin's imperfect family, a passionate testament to her mother's character and courage, and a compelling argument for the right of the terminally ill to a humane and dignified death. The PublicAffairs paperback edition includes a new foreword, questions for thought and discussion, and a helpful resource guide.

    As a lifelong member of "The Nerd Herd," as he calls it, Chris Hardwick has learned all there is to know about Nerds. Developing a system, blog, and podcasts, Hardwick shares hard-earned wisdom about turning seeming weakness into world-dominating strengths in the hilarious self-help book, "The Nerdist Way."From keeping their heart rate below hummingbird levels to managing the avalanche of sadness that is their in-boxes; from becoming evil geniuses to attracting wealth by turning down work, Hardwick reveals the secrets that can help readers achieve their goals by tapping into their true nerdtastic selves.Here Nerds will learn how to: Become their own time cop Tell panic attacks to go suck it Use incremental fitness to ward off predatorsA Nerd's brain is a laser-it's time they learn to point and fire!

    With his trademark humor and frankness, Alan Alda explains what makes the out-of-the-box techniques he developed after his years as the host of Scientific American Frontiers so effective. This book reveals what it means to be a true communicator, and how we can communicate better, in every aspect of our lives—with our friends, lovers, and families, with our doctors, in business settings, and beyond.

    But shuttling between the conference room at work and her couch in front of the TV at home, South couldn't help feeling that she was missing something intangible but essential. So she decided to go looking for it where so many have before: at sea.Six months later, she had quit her job, sold the house, graduated seamanship school and was living aboard a 40-foot, 30-ton steel trawler. Despite South's total lack of experience, the maiden voyage of the rechristened Bossanova was to be a journey up the eastern seaboard. Along with her crew (the dogs and her buddy John—her odd-couple opposite in politics, lifestyle and pretty much everything except a love of the open ocean), she set off on a fifteen-hundred mile odyssey from Florida to Maine. But what began as the fulfillment of an idle wish became a crash course in navigating the byways of the self.The Cure for Anything Is Salt Water traces South's voyage from the charming Americana of Florida's Intracoastal Waterway out into the often stormy waters of the Atlantic. As the trip progresses, South grapples not only with whatever Poseidon throws her way, but also with the ghosts of family and loves lost. For anyone with a secret dream that's gone unfulfilled, here is a reckoning—both funny and poignant—of what's really involved in casting off an old life and making a new one.

    The result of thorough research, keen insight, and unassailable common sense, Good Calories, Bad Calories immediately stirred controversy and acclaim among academics, journalists, and writers alike. Michael Pollan heralded it as “a vitally important book, destined to change the way we think about food.” Building upon this critical work in Good Calories, Bad Calories and presenting fresh evidence for his claim, Taubes now revisits the urgent question of what’s making us fat—and how we can change—in this exciting new book. Persuasive, straightforward, and practical, Why We Get Fat makes Taubes’s crucial argument newly accessible to a wider audience.Taubes reveals the bad nutritional science of the last century, none more damaging or misguided than the “calories-in, calories-out” model of why we get fat, and the good science that has been ignored, especially regarding insulin’s regulation of our fat tissue. He also answers the most persistent questions: Why are some people thin and others fat? What roles do exercise and genetics play in our weight? What foods should we eat, and what foods should we avoid? Packed with essential information and concluding with an easy-to-follow diet, Why We Get Fat is an invaluable key in our understanding of an international epidemic and a guide to what each of us can do about it.