The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    This book is the most engaging, focused and applied HRM text on the market.

    This well presented book guides the reader through the ins and outs of clicker training with graphic step by step illustrations that are ideal for beginners and intermediate clicker trainers. These books will show you the clicker way to train your dog to: Sit to greet people instead of jumping up Walk on the lead without pulling Come when called - everytime Stay home alone quietly Find the right place to "go" Play hide and seek and other fun games and tricks

    Pleasant Animal Shelter"Benjamin writes with love and sensitivity about caring for pets 'adopted' from a shelter."--Publishers Weekly"...a solid training program...a great book."--Job Michael Evans, Dog Fancy"Why a book like this has never before been written is beyond me. It is an invaluable guide to rehabilitating those myriad unfortunate dogs which have either never had a home or have been shuttled from one owner to another, losing confidence, trust and self-esteem every step of the way. It is an absolute must for every owner who wants his second-hand dog to regain the ability to become the warm, loving companion every dog should be."--Kenneth A. Marden, President, The American Kennel Club"...Carol Lea Benjamin has written a witty, sound and thoroughly appropriate book on the extraordinary advantages that each of us who has second-hand pets knows first-hand. If you're thinking about sharing your life with a pet or with another pet, read this book first!"--John F. Kullberg, President, ASPCA

    It uses a taxonomic approach for the study of pathogens.

    The mosquito has become resistant to DDT; malaria is on the rise; although tapeworms rarely turn up any longer in the most lovingly prepared New York City gefilte fish, a worm may inhabit your sashimi; some strains of gonorrhea actually thrive on penicillin; there is even a parasite for the higher tax brackets—the "nymph of Nantucket"; and there are new ailments—legionnaire's disease, Lassa fever, and new strains of influenza.In the long run, one might bet on the insects and the germs. Meanwhile Dr. Robert Desowitz has written a delightful and instructive book.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    For each body system, broad coverage of anatomy, physiology, pathology, diagnostic procedures, treatment procedures, and pharmacology is provided. The author emphasizes both terms built from Latin and Greek word parts, and modern English terms, helping students develop a full working word part vocabulary they can use to interpret any new term. This edition contains many new terms, and has been reorganized for more efficient learning. To eliminate confusion, Word Building tables have been removed from each chapter and the terms have been distributed throughout the pathology, diagnostic procedure, and treatment procedure tables, where they are more immediately relevant to students. Note: This ISBN is just the standalone book, if the customer wants the book/access card order the ISBN below; 133962032 / 9780133962031 Medical Terminology: A Living Language PLUS MyMedicalTerminologyLab with Pearson etext -- Access Card Package Package consists of: 0132843471 / 9780132843478 Medical Terminology: A Living Language 0133936236 / 9780133936230 MyMedicalTerminologyLab with Pearson etext - Access Card - Medical Terminology A Living Language

    It's a hard-bound, 898-page, full-color feast for the senses. Completists will get lost in thousands of freshly-manicured setlists, song histories, and charts. Prose junkies will binge on hundreds of evocative show reviews and fan stories. Photophiles will gape at 128 pages of dazzling Phish photography - most of which has never been published. And poster collectors, get ready: The Phish Companion's eight chapters are anchored by stunning original works from Welker, Masthay, Helton, and more - each of whom was commissioned to freely interpret a period of Phish. No need to wait in line before "doors" for this art. If that's not enough, the net proceeds of your purchase will benefit music education programs via grants from The Mockingbird Foundation. We firmly believe that music is not extracurricular, and we have seen first-hand how your generosity changes lives. Yes, the Phish story is one of epic sweep, but it's also personal. It's about the feeling that overtakes you when the lights go down and the roar comes up. Feel the feeling, right at your fingertips. Read The Book.

    It can be slipped into a drink, smeared onto the tip of an arrow or the handle of a door, even filtered through the air we breathe. But how exactly do these poisons work to break our bodies down, and what can we learn from the damage they inflict?In a blend of popular science, medical history, and true crime, Dr. Neil Bradbury explores the morbidly captivating method of murder from a cellular level. Alongside real-life accounts of murderers and their crimes—some notorious, some forgotten, some still unsolved—are the stories of the poisons involved: eleven molecules of death that work their way through the human body and, paradoxically, illuminate the way in which our bodies function.Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin & tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom.

    Written in a concise, bulleted outline format, this well-illustrated text offers 500 USMLE-style review questions, answers, and explanations and features comprehensive content and upgraded USMLE Step 1 information.

    It's about learning to eat properly for your health." -Vitor Belfort, UFC two-time world champion"Mike Dolce's the best in the business."-Chael Sonnen, UFC world title contender"Mike Dolce's knowledge of nutrition and strength & conditioning has led him to be one of the most highly sought-after coaches in the sport." -Joshua Carey, Bleacher Report"You can learn a lot from this man right here." -Ariel Helwani, AOL's MMAFighting.comABOUT THE DOLCE DIET: LIVING LEANCalled "the patron saint of weight cutting," Mike Dolce has coordinated the high-profile weight loss for many of the world's top athletes, including...* Quinton "Rampage" Jackson, UFC / Pride FC world champion* Vitor "The Phenom" Belfort, UFC two-time world champion* Thiago "Pitbull" Alves, UFC world title contender* Chael Sonnen WEC / UFC world title contender* Gray "Bully" Maynard, UFC world title contender* Nate "Rock" Quarry, UFC world title contender* Mike "Quicksand" Pyle, WEC world champion* Jay "Thorobred" Hieron, IFL world championAs well as fan favorites...* Michael "The Count" Bisping, The Ultimate Fighter 3 winner* Jake "Juggernaut" Ellenberger, UFC veteran* Ed "Shortfuse" Herman, The Ultimate Fighter 3 runner-up* Chris "The Crippler" Leben, UFC veteran* Duane "BANG" Ludwig, UFC & K-1 veteranand many more!For the first time in print, Mike Dolce shares the same the principles, recipes, and strength-training workouts he uses in MMA's elite fight camps and how they can be used by YOU!INSIDE you will learn:* Recipes used in MMA's top fight camps with gluten-free & vegan options* Easy to follow sample meal plans with gluten-free & vegan options* Strength & Conditioning exercises with instructions & photos* Workout plans used by today's top athletesWHAT PEOPLE ARE SAYING ABOUT THE DOLCE DIETThe Dolce Diet, three words about Living Lean: 1. Simple 2. Inspirational 3. Effective. Thank you, Mike Dolce! You've made staying in shape easy! ~STEWART M. The Dolce Diet, Love it! My Little-Boy-2-B has been on it for 5.5 months! This diet is truly amazing for moms pre & post baby! Yes, The DolceDiet is prego friendly! Plenty of the RIGHT kind of food that tastes great! ~THE H2H WAITRESSStarted two weeks ago. Lost 13 pounds so far. Yea! Love the recipes! So do my kids! Thank you! ~DAWN H.Body fat down 4% in 2 months?! Yessss! #LIVING LEAN ~MOLLY C.The Dolce Diet, started 410, down 50 lbs. so far. ~ JOSH W.The Dolce Diet, 13 lbs. lost in 4 weeks! People are asking what I'm doing...Telling them LIVING LEAN! ~MIKE S.Real talk! The Dolce Diet is the Einstein, da Vinci and Jesus of losing weight all wrapped up in one...gluten free wrap that is. ~MIKEY F.Another 5 (lbs. lost) on The Dolce Diet. 25 pounds down in 2 weeks, 100 to go! #LivingLean! ~JOHN P.

    But as animals can only be spied on by getting quite close Heinrich adopts ravens, thereby becoming a "raven father," as well as observing them in their natural habitat, studying their daily routines, and in the process painting a vivid picture of the world as lived by the ravens. At the heart of this book are Heinrich's love and respect for these complex and engaging creatures, and through his keen observation andanalysis, we become their intimates too.Throughout history there has existed an extraordinary relationship between humans and ravens. Ravens, like early humans, are scavengers on the kills of great carnivores. As scavengers, ravens were associated with hunters they found in the north: wolves and, later, men. The trinity of wolf, man, and raven in the hunt is an extremely ancient one. In considering the appeal of the raven, Bernd Heinrich suspects that a meeting of the minds might reside in that hunting trinity.Heinrich's passion for ravens has led him around the world in his research. Mind of the Raven takes you on an exotic journey--from New England to Germany, Montana to Baffin Island in the high Arctic--offering dazzling accounts of how science works in the field, filtered through the eyes of a passionate observer of nature.Heinrich has a true gift; through his stories, his beautiful writing, illustrations, and photography, the ravens come alive. Each new discovery and insight into their behavior is thrilling to read. just as the title promises, the reader is given a rare glimpse into the mind of these wonderful creatures.Following the dictum of Leonardo da Vinci--"It is not enough to believe what you see. YOU Must also understand what you see"--Bernd Heinrich enables us to see the natural world through the eyes of a scientist. At once lyrical and scientific, Mind of the Raven is bound to be a modern classic.

    To meet it, you need a fully integrated text and supplements package that sets the stage for a perfectly choreographed learning experience.

    We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.