He chronicles the torture of finding a job before the internet when you had to talk on the phone all the time, and fantasizes, as we all do, about who to tell off when he finally wins an Oscar. As Gary himself says, "These are essays from my childhood and young adulthood about things that still annoy me."Original, brazen, and laugh out loud funny, Do You Mind if I Cancel? is something not to be missed.

    Parents and family members who never thought they could get inside the head of their autistic loved one, at last, have a way to break through to the curious, subtle, and complex life within.Using an alphabet grid to painstakingly construct words, sentences, and thoughts that he is unable to speak out loud, Naoki answers even the most delicate questions that people want to know. Questions such as: “Why do people with autism talk so loudly and weirdly?” “Why do you line up your toy cars and blocks?” “Why don’t you make eye contact when you’re talking?” and “What’s the reason you jump?” (Naoki’s answer: “When I’m jumping, it’s as if my feelings are going upward to the sky.”) With disarming honesty and a generous heart, Naoki shares his unique point of view on not only autism but life itself. His insights—into the mystery of words, the wonders of laughter, and the elusiveness of memory—are so startling, so strange, and so powerful that you will never look at the world the same way again.

    For decades, Herriot roamed the remote, beautiful Yorkshire Dales, treating every patient that came his way from smallest to largest, and observing animals and humans alike with his keen, loving eye.In All Creatures Great and Small, we meet the young Herriot as he takes up his calling and discovers that the realities of veterinary practice in rural Yorkshire are very different from the sterile setting of veterinary school. Some visits are heart-wrenchingly difficult, such as one to an old man in the village whose very ill dog is his only friend and companion, some are lighthearted and fun, such as Herriot's periodic visits to the overfed and pampered Pekinese Tricki Woo who throws parties and has his own stationery, and yet others are inspirational and enlightening, such as Herriot's recollections of poor farmers who will scrape their meager earnings together to be able to get proper care for their working animals. From seeing to his patients in the depths of winter on the remotest homesteads to dealing with uncooperative owners and critically ill animals, Herriot discovers the wondrous variety and never-ending challenges of veterinary practice as his humor, compassion, and love of the animal world shine forth.James Herriot's memoirs have sold 80 million copies worldwide, and continue to delight and entertain readers of all ages

    In other words, by all of us."--Dr. Bernie Siegel, author of Love, Medicine and MiraclesRule One for the neurologist in residence: "You ain't never the same when the air hits your brain." In this fascinating book, Dr. Frank Vertosick brings that fact to life through intimate portraits of patients and unsparing yet gripping descriptions of brain surgery.With insight, humor, and poignancy, Dr. Vertosick chronicles his remarkable evolution from naive young intern to world-class neurosurgeon, where he faced, among other challenges, a six week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22 caliber bullet lodged in his skull. In candid detail, WHEN THE AIR HITS YOUR BRAIN illuminates both the mysteries of the mind and the realities of the operating room."Riveting."--Publishers Weekly

    Brian Goldman is both an emergency room physician at Mount Sinai and a prominent medical journalist. Never one to shy away from controversy, Goldman specializes in kicking open the doors to the medical establishment, revealing what really goes on behind the scenes -- and in the minds of doctors and nurses.In The Night Shift, Goldman shares his experiences in the witching hours at Mount Sinai Hospital in downtown Toronto. We meet the kinds of patients who walk into an ER after midnight: late-night revellers injured on their way home after last call, teens assaulted in the streets by other teens and a woman who punches another woman out of jealousy over a man. But Goldman also reveals the emotional, heartbreaking side of everyday ER visits: adult children forced to make life and death decisions about critically ill parents, victims of sexual assault, and mentally ill and homeless patients looking for understanding and a quick fix in the twenty-four hour waiting room. Written with Goldman's trademark honesty and with surprising humour, The Night Shift is also a frank look at many issues facing the medical profession today, and offers a highly compelling inside view into an often shrouded world.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    You'd be wrong. When he buys a beach house on the Carolina coast, Sedaris envisions long, relaxing vacations spent playing board games and lounging in the sun with those he loves most. And life at the Sea Section, as he names the vacation home, is exactly as idyllic as he imagined, except for one tiny, vexing realization: it's impossible to take a vacation from yourself.With Calypso, Sedaris sets his formidable powers of observation toward middle age and mortality. Make no mistake: these stories are very, very funny--it's a book that can make you laugh 'til you snort, the way only family can. Sedaris's powers of observation have never been sharper, and his ability to shock readers into laughter unparalleled. But much of the comedy here is born out of that vertiginous moment when your own body betrays you and you realize that the story of your life is made up of more past than future.This is beach reading for people who detest beaches, required reading for those who loathe small talk and love a good tumor joke. Calypso is simultaneously Sedaris's darkest and warmest book yet--and it just might be his very best.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Brought up in Washington, DC, in an abusive family, she went to Harvard, where she met her husband. They stayed together through medical school until two months before she was scheduled to join the staff of a hospital in central Philadelphia, when he told her he couldn't move with her. Her marriage at an end, Harper began her new life in a new city, in a new job, as a newly single woman.In the ensuing years, as Harper learned to become an effective ER physician, bringing insight and empathy to every patient encounter, she came to understand that each of us is broken—physically, emotionally, psychically. How we recognize those breaks, how we try to mend them, and where we go from there are all crucial parts of the healing process.The Beauty in Breaking is the poignant true story of Harper's journey toward self-healing. Each of the patients Harper writes about taught her something important about recuperation and recovery. How to let go of fear even when the future is murky. How to tell the truth when it's simpler to overlook it. How to understand that compassion isn't the same as justice. As she shines a light on the systemic disenfranchisement of the patients she treats as they struggle to maintain their health and dignity, Harper comes to understand the importance of allowing ourselves to make peace with the past as we draw support from the present. In this hopeful, moving, and beautiful book, she passes along the precious, necessary lessons that she has learned as a daughter, a woman, and a physician.

    The colorful characters she meets while delivering babies all over London--from the plucky, warm-hearted nuns with whom she lives to the woman with twenty-four children who can't speak English to the prostitutes and dockers of the city's seedier side--illuminate a fascinating time in history. Beautifully written and utterly moving, The Midwife will touch the hearts of anyone who is, and everyone who has, a mother.

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    Paul A. Ruggieri has seen the good, the bad, and the ugly of his profession. In Confessions of a Surgeon, he pushes open the doors of the O.R. and reveals the inscrutable place where lives are improved, saved, and sometimes lost. He shares the successes, failures, remarkable advances, and camaraderie that make it exciting. He uncovers the truth about the abusive, exhaustive training and the arduous devotion of his old-school education. He explores the twenty-four-hour challenges that come from patients and their loved ones; the ethics of saving the lives of repugnant criminals; the hot-button issues of healthcare, lawsuits, and reimbursements; and the true cost of running a private practice. And he explains the influence of the white coat code of silence and why patients may never know what really transpires during surgery. Ultimately, Dr. Ruggieri lays bare an occupation that to most is as mysterious and unfamiliar as it is misunderstood. His account is passionate, illuminating, and often shocking-an eye-opening, never- before-seen look at real life, and death, in the O.R.

    Afraid of looking like an idiot? Alexandra Petri lost Jeopardy! by answering “Who is that dude?” on national TV. Afraid of bad jokes? Alexandra Petri won an international pun championship.Petri has been a debutante, reenacted the Civil War, and fended off suitors at a Star Wars convention while wearing a Jabba the Hutt suit. One time, she let some cult members she met on the street baptize her, just to be polite. She’s a connoisseur of the kind of awkwardness that most people spend whole lifetimes trying to avoid. If John Hodgman and Amy Sedaris had a baby…they would never let Petri babysit it.But Petri is here to tell you: Everything you fear is not so bad. Trust her. She’s tried it. And in the course of her misadventures, she’s learned that there are worse things out there than awkwardness—and that interesting things start to happen when you stop caring what people think.

    They fell in love at eighteen, married at twenty-four, and were living their dream life in San Francisco. When Giulia was twenty-seven, she suffered a terrifying and unexpected psychotic break that landed her in the psych ward for nearly a month. One day she was vibrant and well-adjusted; the next she was delusional and suicidal, convinced that her loved ones were not safe.Eventually, Giulia fully recovered, and the couple had a son. But, soon after Jonas was born, Giulia had another breakdown, and then a third a few years after that. Pushed to the edge of the abyss, everything the couple had once taken for granted was upended.A story of the fragility of the mind, and the tenacity of the human spirit, My Lovely Wife in the Psych Ward is, above all, a love story that raises profound questions: How do we care for the people we love? What and who do we live for? Breathtaking in its candor, radiant with compassion, and written with dazzling lyricism, Lukach’s is an intensely personal odyssey through the harrowing years of his wife’s mental illness, anchored by an abiding devotion to family that will affirm readers’ faith in the power of love.

    Though he grew up in a large Irish-Catholic family, Jim was satisfied with the nomadic, nocturnal life of a standup comedian, and was content to be "that weird uncle who lives in an apartment by himself in New York that everyone in the family speculates about." But all that changed when he married and found out his wife, Jeannie "is someone who gets pregnant looking at babies."Five kids later, the comedian whose riffs on everything from Hot Pockets to Jesus have scored millions of hits on YouTube, started to tweet about the mistakes and victories of his life as a dad. Those tweets struck such a chord that he soon passed the million followers mark. But it turns out 140 characters are not enough to express all the joys and horrors of life with five kids, so hes' now sharing it all in Dad Is Fat.From new parents to empty nesters to Jim's twenty-something fans, everyone will recognize their own families in these hilarious takes on everything from cousins ("celebrities for little kids") to growing up in a big family ("I always assumed my father had six children so he could have a sufficient lawn crew") to changing diapers in the middle of the night ("like The Hurt Locker but much more dangerous") to bedtime (aka "Negotiating with Terrorists").Dad is Fat is sharply observed, explosively funny, and a cry for help from a man who has realized he and his wife are outnumbered in their own home.