For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    In existence for some hundred million years, it was discovered only recently. Exploring its evolution, its daily existence, and its journey from ticks to mice to deer to humans, Karlen lucidly examines the life and world of this recently prominent germ. He also describes how it attacks the human body, and how by changing the environment, people are now much more likely to come into contact with it. Charming and thorough and smart, this book is a wonderfully written biography of your not so typical biographical subject.

    Harlen Bretz walked the dry scabland channels of eastern Washington in the 1920s, it dawned on him that he was viewing a landscape sculpted by water. Lots of water. A flood of catastrophic proportions. Glacial Lake Missoula and Its Humongous Floods tells the gripping tale of a huge Ice Age lake that drained suddenly--not just once but repeatedly--and reshaped the landscape of the Northwest. The narrative follows the path of the floodwaters as they raged from western Montana across the Idaho Panhandle, then scoured through eastern Washington and down the Columbia Gorge to the Pacific Ocean. This is also the story of geologists grappling with scientific controversy--"of how personalities, pride, and prejudice sometimes superseded scientific evidence."

    Its geology, its unique flora and fauna, and its striking role in human history intersect in surprising and dynamic ways. This book is the most wide-ranging and beautifully illustrated book available on the famous islands. Not since Darwin’s Naturalist’s Voyage has a book combined so much scientific and historic information with firsthand accounts that bring the Galápagos to life.Galápagos: The Islands That Changed the World describes how tragedy and murderous pirates curtailed settlement of the islands and how the islands’ pristine nature, spectacular geology, and defining isolation inspired Darwin’s ideas about evolution. The book explores the diverse land and marine habitats that shelter Galápagos species and considers the islands’ importance today as a frontier for science and a refuge for true wilderness. The book’s extensive gazetteer provides details about endemic plants and animals as well as travel advice about visitors’ sites, diving, photography, when to go, and what to take. Vividly illustrated throughout, this guide is an indispensable reference for natural history enthusiasts, armchair travelers, and island visitors alike.

    • Does Ecstasy cause brain damage? • Why is crack more addictive than cocaine? • What questions regarding drugs are legal to ask in a job interview? • When does marijuana possession carry a greater prison sentence than murder?Illegal Drugs is the first comprehensive reference to offer timely, pertinent information on every drug currently prohibited by law in the United States.  It includes their histories, chemical properties and effects, medical uses and recreational abuses, and associated health problems, as well as addiction and treatment information.Additional survey chapters discuss general and historical information on illegal drug use, the effect of drugs on the brain, the war on drugs, drugs in the workplace, the economy and culture of illegal drugs, and information on thirty-three psychoactive drugs that are legal in the United States, from caffeine, alcohol and tobacco to betel nuts and kava kava.This book is a must-have resource for students, parents, health care workers, law enforcement officers, and anyone else who needs accurate information about drugs.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    one in 25 of the people around you is a psychopath, hiding and living a secret life. Psychopaths take what they want, using their charm and wits. They feel only the emotions of a predator. In this book Pieter Hintjens decodes the mystery of the psychopath. Why do such people exist? How do they operate? And most critical of all, can we learn to avoid them, or escape them? The answers will enlighten you. This book delivers practical tools and techniques to survive the most difficult people.

    Top magazines including Fortune and Industry Week have repeatedly named it one of America's best companies to work for.In Science Lessons, Gordon Binder—CEO and chairman during 1988-2000—describes Amgen's climb to success. Revealing the highs and lows it experienced in the race to develop blockbuster drugs, he takes readers from the time Amgen had just three months of capital in the bank and no viable products in the pipeline to its spectacular success. The turning point? The 1989 launch of Epogen, which dramatically helped kidney dialysis patients suffering from debilitating anemia. Other landmark drugs, including Neupogen, would follow.Through engaging anecdotes and cogent insights, Binder weaves a fascinating tale while offering his unique brand of practical management advice. Using the principals of the scientific method, he shares his recommendations for tackling pressing business challenges—such as managing creative employees, navigating the IPO process, and protecting intellectual property.This colorful first-person account showcases the visionary science and daring business strategy that made Amgen great—offering valuable lessons for all companies.

    As a wildlife biologist and conservationist, Galante devotes his life to studying, rediscovering, and protecting our planet’s amazing lifeforms. Part memoir, part biological adventure, Still Alive celebrates the beauty and determined resiliency of our world, as well as the brave conservationists fighting to save it.  In his debut book, Galante takes readers on an exhilarating journey to the most remote and dangerous corners of the world. He recounts miraculous rediscoveries of species that were thought to be extinct and invites readers into his wild life: from his upbringing amidst civil unrest in Zimbabwe to his many globetrotting adventures, including suspenseful run-ins with drug cartels, witch doctors, and vengeful government officials.  He shares all of the life-threatening bites, fights, falls, and jungle illnesses. He also investigates the connection between wildlife mistreatment and human safety, particularly in relation to COVID-19.  Still Alive is much more than just a can’t-put-down adventure story bursting with man-eating crocodiles, long-forgotten species rediscovered, and near-death experiences. It is an impassioned, informative, and undeniably inspiring examination of the importance of wildlife conservation today and how every individual can make a difference.

    Tennessee schoolteacher John Scopes brought the question of teaching evolution in schools to every dinner table, and it remains an essential topic in any course on American History, the History of Education, and Religious History. This volume’s lively interpretative introduction provides an analysis of the trial and its impact on the moral fiber of the country and the educational system, and examines the race and gender issues that shook out of the debate. The editor has excerpted the crucial exchanges from the trial transcript itself, and includes these along with reactions to the trial, taken from newspaper reports, letters, and magazine articles. Telling political cartoons and evocative photographs add a colorful dimension to this collection, while a chronology of events, questions for consideration, and a bibliography provide strong pedagogical support.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    Touching the Wild is the enchanting story about one man who has lived with a herd of mule deer in the Wind River mountains of Wyoming for almost seven years. Why, you may ask, would a person choose to do such a thing? His response: how could you not? For Joe Hutto, close proximity to wild things is irresistible. In Illumination in the Flatwoods he unveiled the secret lives of the wild turkey to great critical acclaim. In Touching the Wild he turns his acute sense of wonder and affinity to one of the West's quintessential big game animals: the mule deer, a species in peril due to environmental factors. Wily, thoughtful creatures, mule deer are not inclined to make foolish friendships with their primary predator-man. But due to the intense curiosity of one small doe, and the resulting introduction to an entire herd, Joe Hutto has been allowed unprecedented access and insight into the minds and behavior of this special animal.Spending every day among the herd, he develops uncanny connections with the deer, learning individual and group dynamics as well, unveiling just how much we have in common with these delicate beings. Each season brings new joy as fawns are born and heartache as matriarchs pass away, or hunting takes its toll, or a fawn is orphaned. But what overwhelmingly emerges from Touching the Wild is the enormous respect Hutto has for all wild things and the recognition that we have so much to learn from them about their world, ourselves, and the fragile planet we share. Throughout the book are gorgeous full-color photos.

    But events conspired to fling Carter Niemeyer westward and straight into the jaws of wolves. From his early years wrangling ornery federal trappers, eagles and grizzlies, to winning a skinning contest that paved the way for wolf reintroduction in the Northern Rockies, Carter Niemeyer reveals the wild and bumpy ride that turned a trapper - a killer - into a champion of wolves.

    Meet the Crazy Ones who created Silicon Valley – the hippies who started the Homebrew Computer Club; the young ad executive who first sketched out Apple’s iconic logo; the engineers who met lying down in a cardboard geodesic dome at Stanford University. From Steve Wozniak, who built the first breakthrough Apple computers, to Jony Ive, the young Brit who imagined the iPod - the designers and programmers, the geeks, creatives and dreamers, they are all here.And at the centre of it all, a bearded and barefoot Steve Jobs, whose singular vision would will Apple Inc. into a future that it would come to own …

    Worms are the latest (as well as, of course, perhaps the oldest!) trend in earth-friendly gardening, and in this handy guide, the authors of DEAD SNAILS LEAVE NO TRAILS demystify the world of worm wrangling, with everything you need to know to build your own worm bin, make your garden worm-friendly, pamper your soil, and much much more.