The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.

    Bryan Derrickson of Valencia Community College in Orlando, Florida joins Jerry Tortora as a co-author, bringing his background and expertise in physiology in balance with Jerry's focus on anatomy. The authors have maintained in the text the superb balance between structure and function and continue to emphasize the correlations between normal physiology and pathophysiology, normal anatomy and pathology, and homeostasis and homeostatic imbalances. The acclaimed illustration program is now even better thanks to the input of hundreds of professors and students and the re-development of many of the figures depicting the toughest topics for students to grasp. The eleventh edition now fully integrates this exceptional text with a host of innovative electronic media, setting the standard once again for a rewarding and successful classroom experience for both students and instructors.

    Sybil became both a pop phenomenon and a revolutionary force in the psychotherapy industry. The book rocketed multiple personality disorder (MPD) into public consciousness and played a major role in having the diagnosis added to the psychiatric bible, Diagnostic and Statistical Manual of Mental Disorders. But what do we really know about how Sybil came to be? In her news-breaking book Sybil Exposed, journalist Debbie Nathan gives proof that the allegedly true story was largely fabricated. The actual identity of Sybil (Shirley Mason) has been available for some years, as has the idea that the book might have been exaggerated. But in Sybil Exposed, Nathan reveals what really powered the legend: a trio of women—the willing patient, her ambitious shrink, and the imaginative journalist who spun their story into bestseller gold. From horrendously irresponsible therapeutic practices—Sybil’s psychiatrist often brought an electroshock machine to Sybil’s apartment and climbed into bed with her while administering the treatment— to calculated business decisions (under an entity they named Sybil, Inc., the women signed a contract designating a three-way split of profits from the book and its spin-offs, including board games, tee shirts, and dolls), the story Nathan unfurls is full of over-the-top behavior. Sybil’s psychiatrist, driven by undisciplined idealism and galloping professional ambition, subjected the young woman to years of antipsychotics, psychedelics, uppers, and downers, including an untold number of injections with Pentothal, once known as “truth serum” but now widely recognized to provoke fantasies. It was during these “treatments” that Sybil produced rambling, garbled, and probably “false-memory”–based narratives of the hideous child abuse that her psychiatrist said caused her MPD. Sybil Exposed uses investigative journalism to tell a fascinating tale that reads like fiction but is fact. Nathan has followed an enormous trail of papers, records, photos, and tapes to unearth the lives and passions of these three women. The Sybil archive became available to the public only recently, and Nathan examined all of it and provides proof that the story was an elaborate fraud—albeit one that the perpetrators may have half-believed. Before Sybil was published, there had been fewer than 200 known cases of MPD; within just a few years after, more than 40,000 people would be diagnosed with it. Set across the twentieth century and rooted in a time when few professional roles were available to women, this is a story of corrosive sexism, unchecked ambition, and shaky theories of psychoanalysis exuberantly and drastically practiced. It is the story of how one modest young woman’s life turned psychiatry on its head and radically changed the course of therapy, and our culture, as well.

    Extensively illustrated and user-friendly, the text offers examples pf how knowledge of biochemistry is essential for understanding the molecular basis of health and disease. The 26th edition also features expanded content on results of the Human Genome Project. Perfect as both text and USMLE review.

    But compulsions exist along a broad continuum, and at the opposite end of these mild forms exist life altering disorders. Sharon Begley’s meticulously researched book is the first of its kind to examine all of these behaviors—mild and extreme (OCD, hoarding, acquiring, exercise, even compulsions to do good)—together, as they should be, because while forms of compulsion may look incredibly different, these are actually all coping responses to varying degrees of anxiety. With a focus on personal stories of dozens of interviewees, Begley employs genuine compassion and gives meaningful context to their plight. Along the way she explores the role of compulsion in our fast paced culture, the brain science behind it, and strange manifestations of the behavior throughout history. Can’t Just Stop makes compulsion comprehensible and accessible, exploring how we can realistically grapple with it in ourselves and those we love.

    We are now beginning to learn that many forms of psychotherapy, developed in the absence of any scientific understanding of the brain, are supported by neuroscientific findings.Louis Cozolino's The Neuroscience of Psychotherapy illustrates in a clearly written and accessible way how the brain's architecture is related to the problems, passions, and aspirations of human beings. As Cozolino so eloquently argues, all forms of psychotherapy-from psychoanalysis to behavioral interventions-are successful to the extent to which they enhance change in relevant neural circuits.Beginning with an overview of the intersecting fields of neuroscience and psychotherapy, this book delves into the brain's inner workings, from basic neuronal building blocks to complex systems of memory, language, and the organization of experience. It continues by explaining the development and organization of the healthy brain and the unhealthy brain. Common problems such as anxiety, trauma, and codependency are discussed from a scientific and clinical perspective. Cozolino concludes by introducing the emerging paradigm of the psychotherapist-as-neuroscientist and presents some practical applications of neuroscience to psychotherapy. Throughout the book, the science behind the brain's workings is applied to day-to-day experience and clinical practice.Written for psychotherapists and others interested in the relationship between brain and behavior, this book encourages us to consider the brain when attempting to understand human development, mental illness, and psychological health.

    A gifted writer, Vertosick shows us that intelligence - the ability to react to the outside world, to change behaviour, to survive - can be found wherever life exists. He demonstrates the keen intelligence of our immune system, how lowly bacteria mutate and outwit antibiotics, and how canny cancer cells elude our natural defences.

    And now he's showing the way to build the very foundation of well-being: Resilience. Today, people feel rattled by political and economic forces, and realize that they need to be able to rely on their own inner guidance systems in order to stay happy and calm. Not simply about weathering negative experiences, Resilient's groundbreaking program shows you how to harness the power of positive experiences in order to build an unshakeable core.In this succinct guide to lasting happiness, Dr. Hanson has distilled 40 years of clinical work and teaching into the tools that actually work. Each of these 12 tools grows a key inner strength for resilience, allowing you to enter a positive cycle in which resilience creates a sense of well-being, which creates even more resilience, and so on. Developed from his incredibly popular online course called The Foundations of Well-Being, this essential book offers everything you need to shore up these powerful inner strengths. In his inimitable friendly, warm, straightforward tone, Dr. Hanson shares stories, support, and simple thoughts and actions that lead to deeply rooted change. Here is the groundwork that will allow you to meet life with a whole heart.

    Hailed as the most outstanding book in the biomedical sciences when it was originally published in 1990, Manic-Depressive Illness was the first to survey this massive body of evidence comprehensively and to assess its meaning for both clinician and scientist. It also vividly portrayed the experience of manic-depressive illness from the perspective of patients, their doctors, and researchers. Encompassing an understanding about the illness as Kraeplin conceived of it- about its cyclical course and about the essential unity of its bipolar and recurrent unipolar forms- the book has become the definitive work on the topic, revered by both specialists and nonspecialists alike. Now, in this magnificent second edition, Drs. Frederick Goodwin and Kay Redfield Jamison bring their unique contribution to mental health science into the 21st century. In collaboration with a team of other leading scientists, a collaboration designed to preserve the unified voice of the two authors, they exhaustively review the biological and genetic literature that has dominated the field in recent years and incorporate cutting-edge research conducted since publication of the first edition. They also update their surveys of psychological and epidemiological evidence, as well as that pertaining to diagnostic issues, course, and outcome, and they offer practical guidelines for differential diagnosis and clinical management. The medical treatment of manic and depressive episodes is described, strategies for preventing future episodes are given in detail, and psychotherapeutic issues common in this illness are considered. Special emphasis is given to fostering compliance with medication regimens and treating patients who abuse drugs and alcohol or who pose a risk of suicide. This book, unique in the way that it retains the distinct perspective of its authors while assuring the maximum in-depth coverage of a vastly expanded base of scientific knowledge, will be a valuable and necessary addition to the libraries of psychiatrists and other physicians, psychologists, clinical social workers, neuroscientists, pharmacologists, and the patients and families who live with manic-depressive illness.

    Objects in harmonic motion have the ability to transfer some of their energy over large distances. Light Nature: This chapter covers the nature of light, polarization, and color.

    Richard Louis Miller discusses what is happening today in psychedelic medicine--and what will happen in the future--with top researchers and thinkers in this field, including Rick Doblin, Stanislav Grof, James Fadiman, Julie Holland, Dennis McKenna, David Nichols, Charles Grob, Phil Wolfson, Michael and Annie Mithoefer, Roland Griffiths, Katherine MacLean, and Robert Whitaker. Dr. Miller and his contributors cover the tumultuous history of early psychedelic research brought to a halt 50 years ago by the U.S. government as well as offering non-technical summaries of the most recent studies with MDMA, psilocybin, LSD, and ayahuasca. They explore the biochemistry of consciousness and the use of psychedelics for self-discovery and healing. They discuss the use of psilocybin for releasing fear in the terminally ill and the potential for MDMA-assisted psychotherapy in the treatment of PTSD. They examine Dr. Charles Grob’s research on the indigenous use and therapeutic properties of ayahuasca and Dr. Gabor Mate’s attempt to transport this plant medicine to a clinical setting with the help of Canada’s Department of National Health. Dr. Miller and his contributors explore the ongoing efforts to restore psychedelic therapies to the health field, the growing threat of overmedication by the pharmaceutical industry, and the links between psychiatric drugs and mental illness. They also discuss the newly shifting political climate and the push for new research, offering hope for an end to the War on Drugs and a potential renaissance of research into psychedelic medicines around the world.

    In Nobody’s Normal, anthropologist Roy Richard Grinker chronicles the progress and setbacks in the struggle against mental-illness stigma—from the eighteenth century, through America’s major wars, and into today’s high-tech economy.Grinker infuses the book with the personal history of his family’s four generations of involvement in psychiatry, including his grandfather’s analysis with Sigmund Freud, his own daughter’s experience with autism, and culminating in his research on neurodiversity. Drawing on cutting-edge science, historical archives, and cross-cultural research in Africa and Asia, Nobody’s Normal explains how we are transforming mental illness and offers a path to end the shadow of stigma. The preeminent historian of medicine, Sander Gilman, calls Nobody’s Normal “the most important work on stigma in more than half a century.”

    Three eminent psychiatrists tackle the difficult task of reconciling what artists and thinkers have known for thousands of years about the human heart with what has only recently been learned about the primitive functions of the human brain.A General Theory of Love demonstrates that our nervous systems are not self-contained: from earliest childhood, our brains actually link with those of the people close to us, in a silent rhythm that alters the very structure of our brains, establishes life-long emotional patterns, and makes us, in large part, who we are. Explaining how relationships function, how parents shape their child’s developing self, how psychotherapy really works, and how our society dangerously flouts essential emotional laws, this is a work of rare passion and eloquence that will forever change the way you think about human intimacy.

    Richard Restak, Brainis both a practical owner’s manual and a complete guide to the brain’s development and function. Its pages explore not only the brain’s physical form—its 100 billion nerve cells and near-infinite network of synapses—but also its interactions that regulate every thought and action. Brainfeatures the latest discoveries about improving and optimizing mental acuity right alongside sidebars on breakthrough moments in neuroscience. Explained here also are the physical, emotional, and psychological aspects of the brain, addressed in accessible, engaging language.Combining the latest advances in our understanding of the mind-body connection and ongoing research into such diseases as dementia, depression, and PTSD, Brainis an indispensable guide to mens sana in corpore sano—at every stage of life.

    Longer training, ever more advanced technologies—neither seems to prevent grievous errors. But in a hopeful turn, acclaimed surgeon and writer Atul Gawande finds a remedy in the humblest and simplest of techniques: the checklist. First introduced decades ago by the U.S. Air Force, checklists have enabled pilots to fly aircraft of mind-boggling sophistication. Now innovative checklists are being adopted in hospitals around the world, helping doctors and nurses respond to everything from flu epidemics to avalanches. Even in the immensely complex world of surgery, a simple ninety-second variant has cut the rate of fatalities by more than a third.In riveting stories, Gawande takes us from Austria, where an emergency checklist saved a drowning victim who had spent half an hour underwater, to Michigan, where a cleanliness checklist in intensive care units virtually eliminated a type of deadly hospital infection. He explains how checklists actually work to prompt striking and immediate improvements. And he follows the checklist revolution into fields well beyond medicine, from disaster response to investment banking, skyscraper construction, and businesses of all kinds.An intellectual adventure in which lives are lost and saved and one simple idea makes a tremendous difference, The Checklist Manifesto is essential reading for anyone working to get things right.