Here's the first in a new series of in-depth discussions on a variety of subjects relating to humanity's greatest endeavors.Around the table, Ricky Gervais, Steve Merchant, and the glabrous luminary Karl Pilkington.In this episode, MEDICINE, we explore the treatment of human ailments through history - from trepanation (or 'oles in the 'ed) in early tribal societies right through to the possible, if improbable, future of medical technology.Ricky Steve and Karl offer a uniquely ill-informed appraisal, from medicine's superstitious roots in shamanism, the beginnings of empiricism and on to today's holistic ideal.Areas of discussion include the dangers of leaving yoghurt pots in fridges; how over-enthusiastic janitors can stifle scientific progress; how hygiene impacts on immunity; Karl's ideas on empathic diagnosis; fruit-based contraception; the risks of eye surgery; the politics of treating obesity; conjugal care-workers; geriatric clinical trials; Karl's take on palliative care; and the inevitable anal-probing....

    Or a bad burrito. (He’s also eaten a 76-ounce steak, asserted that his wife’s post-pregnancy jeans were the best-fitting pants he ever wore, and was asked by his own childhood doctor if his “feminine shape” embarrassed him at the beach.) In Down Size, Ted takes readers on an inspiring, candid, and comical journey, exploring the art and science of weight loss throughhis own struggles as a pear-shaped man in a not-so-pear-shaped world, with research about food, exercise, and the psychology of losing weight. He reveals twelve truths about successful weight loss, in areas such as temptation, frustration, nutrition, and inspiration. Some truths:• Redefine the Definition of Data• Leave Behind Your Extra Gland• Think Process, Not Outcome• Train Shorter, Train Harder Combining science, personal stories, expert interviews, and advice, Down Size is an entertaining, field-tested, and research-based look at how men and women can finally find the body they want.

    Sidibe tells the engrossing, inspiring story of her first job as a phone sex “talker.” And she shares her unconventional (of course!) rise to fame as a movie star, alongside “a superstar cast of rich people who lived in mansions and had their own private islands and amazing careers while I lived in my mom's apartment.” Sidibe’s memoir hits hard with self-knowing dispatches on friendship, depression, celebrity, haters, fashion, race, and weight (“If I could just get the world to see me the way I see myself,” she writes, “would my body still be a thing you walked away thinking about?”). Irreverent, hilarious, and nontraditional, This Is Just My Face takes its place and fills a void on the shelf of writers from Mindy Kaling to David Sedaris to Lena Dunham.

    Now Whoopi speaks openly about why marriage isn't for everyone, how being alone can be satisfying, and how what's most important is understanding who you are and what makes you happy. Wise, funny, and conversation-starting, Whoopi's message is sure to resonate with the millions of people who struggle with relationships every day. Goldberg says: "I get to hear from a lot of different people about relationships, and this got me trying to figure out why the divorce rate is SO high. It occurred to me that as one who has done it badly often, I might have some insight. It's hard to really know the other person's agenda, but if someone says 'you complete me' ... RUN!!!"

    Kitchen Confidential reveals what Bourdain calls "twenty-five years of sex, drugs, bad behavior and haute cuisine."

    The GQ correspondent and Deadspin columnist’s stories about trying to raise a family have attracted millions of readers online. And now he’s finally bringing that unique voice to a memoir. In Someone Could Get Hurt, he reflects on his own parenting experiences to explore the anxiety, rationalizations, compromises, and overpowering love that come with raising children in contemporary America. In brutally honest and funny stories, Magary reveals how American mothers and fathers cope with being in over their heads (getting drunk while trick-or-treating, watching helplessly as a child defiantly pees in a hotel pool, engaging in role-play with a princess-crazed daughter), and how stepping back can sometimes make all the difference (talking a toddler down from the third story of a netted-in playhouse, allowing children to make little mistakes in the kitchen to keep them from making the bigger ones in life). It’s a celebration of all the surprises—joyful and otherwise—that come with being part of a real family. In the wake of recent bestsellers that expose how every other culture raises their children better, Someone Could Get Hurt offers a hilarious and heartfelt defense of American child rearing with a glimpse into the genuine love and compassion that accompany the missteps and flawed logic. It’s the story of head lice, almost-dirty words, and flat head syndrome, and a man trying to commit the ultimate act of selflessness in a selfish world.

    In his first-ever series of essays, Al details his childhood in Brooklyn and Queens and his start on a local channel in Syracuse while still in college, before making the move back to his NYC hometown and prime-time weather casting. Al's trademark good humor and keen reportage have made him one of the country's most trusted faces on television, but in this book, Al gives readers an all-access pass to his life beyond the screen. From co-parenting with his award-winning journalist wife, Deborah Roberts, and starting up his own production company, to his latest stint on Broadway in Waitress, Al has built up a wealth of knowledge and guidance. He has plenty to say about the good times and the bad; being mentored by Willard Scott; what he's learned from working with news legends from Katie Couric and Bryant Gumbel to contemporaries like Savannah Guthrie, Hoda Kotb and Lester Holt; and moments where he held his tongue--and wishes he hadn't.A 13-time Emmy winner and New York Times bestselling author, Al knows how to tell a good story. This behind-the-scenes look at a career in the media, filled with missteps and successes, will leave you laughing out loud--and inspired.

    But a light so bright never really goes out, especially since, in her last few months, Keelin wrote a fantastic record of her life.Charting the twists and turns of both a remarkable career as an investigative journalist and a lengthy battle with cancer, in A Light That Never Goes Out Keelin reveals with real honesty what it's like to keep living your life and career - right up to becoming a co-anchor of RT�'s Six One News - while dealing with the challenges of cancer treatment.Written with the help of Alison Walsh and completed posthumously by Keelin's husband Conor Ferguson, A Light That Never Goes Out is a remarkable story of courage and resilience and a memorable reflection on how to live well, no matter what you're facing.

    Or, rather, to welcome him back. It had been thirty years since the Revolutionary War hero the Marquis de Lafayette had last set foot in the United States, and he was so beloved that 80,000 people showed up to cheer for him. The entire population of New York at the time was 120,000. Lafayette's arrival in 1824 coincided with one of the most contentious presidential elections in American history, Congress had just fought its first epic battle over slavery, and the threat of a Civil War loomed. But Lafayette, belonging to neither North nor South, to no political party or faction, was a walking, talking reminder of the sacrifices and bravery of the revolutionary generation and what they wanted this country to be. His return was not just a reunion with his beloved Americans, it was a reunion for Americans with their own astonishing singular past. Lafayette in the Somewhat United States is a humorous and insightful portrait of the famed Frenchman, the impact he had on our young country, and his ongoing relationship with some of the instrumental Americans of the time, including George Washington, Alexander Hamilton, Thomas Jefferson, and many more.

    In the rain.In this compelling memoir, comedian and actor Alan Davies recalls his boyhood with vivid insight and devastating humour. Shifting between his 1970s upbringing and his life today, Davies moves poignantly from innocence to experience to the clarity of hindsight, always with a keen sense of the absurd.From sibling dynamics, to his voiceless, misunderstood progression through school, sexuality and humiliating 'accidents', Davies inhabits his younger mind with spectacular accuracy, sharply evoking an era when Green Shield Stamps, Bob-a-Job week and Whizzer & Chips loomed large, a bus fare was 2p - and children had little power in the face of adult motivation. Here, there are often exquisitely tender recollections of the mother he lost at six years old, of a bereaved family struggling to find its way, and the kicks and confusion of adolescence.

    But Saturday Night Live, launched in 1975 and still thriving today, would change the face of television. It introduced brash new stars with names like Belushi, Radner, Chase, and Murray; trashed taboos that had inhibited TV for decades; and had such an impact on American life, laughter, and politics that even presidents of the United States had to take notice. Now, Pulitzer Prize-winner Tom Shales and bestselling author James Andrew Miller bring together stars, writers, guest hosts, contributors, and craftsmen for the first-ever oral history of Saturday Night Live, from 1974, when it was just an idea, through 2002, when it has long since become an institution. In their own words, dozens of personalities recall the backstage stories, behind-the-scenes gossip, feuds, foibles, drugs, sex, struggles, and calamities, including personal details never before revealed. Shales and Miller have interviewed a galaxy of stars, including Mike Myers, Chris Rock, Bill Murray, Tom Hanks, Adam Sandler, Chevy Chase, Will Ferrell, Dan Aykroyd, Steve Martin, Jon Lovitz, Jane Curtin, Billy Crystal, Martin Short, Dana Carvey, Tina Fey, Jimmy Fallon, Chris Kattan, Julia Louis-Dreyfus, Garrett Morris, Molly Shannon, Damon Wayans, Chris Elliott, Julia Sweeney, Norm Macdonald, and Paul Simon-plus writers like Al Franken, Conan O'Brien, Larry David, Rosie Shuster, Jack Handey, Robert Smigel, Don Novello, and others who got their big breaks as part of the SNL team. The Coneheads, the Blues Brothers, Buck-wheat, Wayne and Garth, Hans and Franz, the Cheerleaders, Todd DiLaMuca and Lisa Loopner, "Cheeseburger cheeseburger," Mango, the Church Lady, Ed Grimley-they're all here. And for every fabulous character on-screen there was an outrageous maverick, misfit, or rebel behind the scenes. Live from New York does what no other book about the show has ever done: It lets the people who were there tell the story in their own words, blunt and loving and uncensored.

    You've seen him on the street, in bars, on the subway, at restaurants: a twenty-something guy, nice suit, works in advertising. Regular. Ordinary. But when the ordinary person had two drinks, Augusten was circling the drain by having twelve; when the ordinary person went home at midnight, Augusten never went home at all. Loud, distracting ties, automated wake-up calls, and cologne on the tongue could only hide so much for so long. At the request (well, it wasn't really a request) of his employers, Augusten landed in rehab, where his dreams of group therapy with Robert Downey, Jr., are immediately dashed by the grim reality of fluorescent lighting and paper hospital slippers. But when Augusten is forced to examine himself, something actually starts to click, and that's when he finds himself in the worst trouble of all. Because when his thirty days are up, he has to return to his same drunken Manhattan life and live it sober. What follows is a memoir that's as moving as it is funny, as heartbreaking as it is real.

    Best-selling author and Rolling Stone columnist Rob Sheffield explores the music and artistry of the rock goddess who has kept generations of music lovers totally bewitched and spellbound, with such classic rock hits as "Rhiannon" and "Gypsy". With her recent induction into the Rock & Roll Hall of Fame (the only female artist to be honored for both her group and solo work), Nicks, who turns 70 this month, is being celebrated for living the seasons of her life with ferocious wit, fierce honesty, unstoppable talent, and a lot of rock & roll. Drawing from Rolling Stone magazine’s extensive archives, and his long time appreciation of Nicks, Sheffield shares the stories behind the best-selling records and the spitfire 1997 Fleetwood Mac reunion show that put the band back on top of the charts—and why Stevie Nicks still speaks to us today. A dynamic, revelatory sketch of the one-of-a-kind icon, The Wild Heart of Stevie Nicks is a portrait as revealing as it is dazzling, as human as it is pure magic

    Doubtfire—as a brilliant new chronicler of the experience that is growing up young and female.   Mara Wilson has always felt a little young and a little out of place: as the only child on a film set full of adults, the first daughter in a house full of boys, the sole clinically depressed member of the cheerleading squad, a valley girl in New York and a neurotic in California, and one of the few former child actors who has never been in jail or rehab. Tackling everything from how she first learned about sex on the set of Melrose Place, to losing her mother at a young age, to getting her first kiss (or was it kisses?) on a celebrity canoe trip, to not being “cute” enough to make it in Hollywood, these essays tell the story of one young woman’s journey from accidental fame to relative (but happy) obscurity. But they also illuminate a universal struggle: learning to accept yourself, and figuring out who you are and where you belong. Exquisitely crafted, revelatory, and full of the crack comic timing that has made Mara Wilson a sought-after live storyteller and Twitter star, Where Am I Now? introduces a witty, perceptive, and refreshingly candid new literary voice.

    Fortunately, many smart philosophers have been pondering this conundrum for millennia and they have guidance for us. With bright wit and deep insight, How to Be Perfect explains concepts like deontology, utilitarianism, existentialism, ubuntu, and more so we can sound cool at parties and become better people. Schur starts off with easy ethical questions like “Should I punch my friend in the face for no reason?” (No.) and works his way up to the most complex moral issues we all face. Such as: Can I still enjoy great art if it was created by terrible people? How much money should I give to charity? Why bother being good at all when there are no consequences for being bad? And much more. By the time the book is done, we’ll know exactly how to act in every conceivable situation, so as to produce a verifiably maximal amount of moral good. We will be perfect, and all our friends will be jealous. OK, not quite. Instead, we’ll gain fresh, funny, inspiring wisdom on the toughest issues we face every day.